AccidentalPsychiatrist
@accidentalpsych.bsky.social
Reposted by AccidentalPsychiatrist
Saffron beat placebo in mild, subclinical #depression, largest trial yet of this low-cost herb (n=202, effect size 0.44)
Saffron has multiple RCTs in depression, but most from Iran; this (industry sponsored) one is not:
ncbi.nlm.nih.gov/pubmed/40414301
How to use:
chrisaikenmd.com/supplements
Saffron has multiple RCTs in depression, but most from Iran; this (industry sponsored) one is not:
ncbi.nlm.nih.gov/pubmed/40414301
How to use:
chrisaikenmd.com/supplements
June 3, 2025 at 11:43 PM
Saffron beat placebo in mild, subclinical #depression, largest trial yet of this low-cost herb (n=202, effect size 0.44)
Saffron has multiple RCTs in depression, but most from Iran; this (industry sponsored) one is not:
ncbi.nlm.nih.gov/pubmed/40414301
How to use:
chrisaikenmd.com/supplements
Saffron has multiple RCTs in depression, but most from Iran; this (industry sponsored) one is not:
ncbi.nlm.nih.gov/pubmed/40414301
How to use:
chrisaikenmd.com/supplements
Reposted by AccidentalPsychiatrist
Reposted by AccidentalPsychiatrist
Hey remember when people said “we need a domestic terrorism statute” and people like me said “that would be super ripe for abuse for whatever lunatic is in power, would you want Trump to have that power” and you sneered at “slippery slope thinking”? Yeah, I remember, dipshit.
President Trump says that he is going to label incidents of violence/vandalism at Tesla dealerships as “domestic terrorism.”
March 11, 2025 at 9:56 PM
Hey remember when people said “we need a domestic terrorism statute” and people like me said “that would be super ripe for abuse for whatever lunatic is in power, would you want Trump to have that power” and you sneered at “slippery slope thinking”? Yeah, I remember, dipshit.
Reposted by AccidentalPsychiatrist
Besides antidepressants, what works in mild depression?
Therapy, exercise, probiotics, omega3, St Johns Wort, Rhodiola rosea, lavender, lemon balm, electroacupuncture stimulation:
www.ncbi.nlm.nih.gov/pubmed/40014...
How to use supplements in #depression:
chrisaikenmd.com/supplements
#psychiatry
Therapy, exercise, probiotics, omega3, St Johns Wort, Rhodiola rosea, lavender, lemon balm, electroacupuncture stimulation:
www.ncbi.nlm.nih.gov/pubmed/40014...
How to use supplements in #depression:
chrisaikenmd.com/supplements
#psychiatry
March 9, 2025 at 7:30 PM
Besides antidepressants, what works in mild depression?
Therapy, exercise, probiotics, omega3, St Johns Wort, Rhodiola rosea, lavender, lemon balm, electroacupuncture stimulation:
www.ncbi.nlm.nih.gov/pubmed/40014...
How to use supplements in #depression:
chrisaikenmd.com/supplements
#psychiatry
Therapy, exercise, probiotics, omega3, St Johns Wort, Rhodiola rosea, lavender, lemon balm, electroacupuncture stimulation:
www.ncbi.nlm.nih.gov/pubmed/40014...
How to use supplements in #depression:
chrisaikenmd.com/supplements
#psychiatry
Reposted by AccidentalPsychiatrist
Part of the lesson here is that Trumpists, like many bullies, don’t handle it well if you stand up to them rather than caving. If Trump or Vance or their supporters had any character this petulant display and Zelenskyy’s defiance would be humiliating to them.
Zelenskyy gives a thumbs up after getting berated by a visibly agitated Trump
February 28, 2025 at 5:57 PM
Part of the lesson here is that Trumpists, like many bullies, don’t handle it well if you stand up to them rather than caving. If Trump or Vance or their supporters had any character this petulant display and Zelenskyy’s defiance would be humiliating to them.
Reposted by AccidentalPsychiatrist
Donald Trump has disgraced the United States of America in countless ways since he first entered political life ten years ago.
But he had never disgraced the nation as badly as he did today.
He has brought shame on this country to an extent I had never thought possible. And he has only just begun.
But he had never disgraced the nation as badly as he did today.
He has brought shame on this country to an extent I had never thought possible. And he has only just begun.
February 28, 2025 at 9:41 PM
Donald Trump has disgraced the United States of America in countless ways since he first entered political life ten years ago.
But he had never disgraced the nation as badly as he did today.
He has brought shame on this country to an extent I had never thought possible. And he has only just begun.
But he had never disgraced the nation as badly as he did today.
He has brought shame on this country to an extent I had never thought possible. And he has only just begun.
Reposted by AccidentalPsychiatrist
The Trumpists will LOVE the international condemnation of this farce. They’re fundamentally trolls: “oh seems like you’re triggered.”
March 1, 2025 at 12:33 AM
The Trumpists will LOVE the international condemnation of this farce. They’re fundamentally trolls: “oh seems like you’re triggered.”
Reposted by AccidentalPsychiatrist
Today was a grim, terrible day for the United States and the cause of democracy. Putin, along with other dictators around the world, can finally look at Trump with confidence and think: one of us.
www.theatlantic.com/ideas/archiv...
www.theatlantic.com/ideas/archiv...
It Was an Ambush
Today marked one of the grimmest days in the history of American diplomacy.
www.theatlantic.com
March 1, 2025 at 12:56 AM
Today was a grim, terrible day for the United States and the cause of democracy. Putin, along with other dictators around the world, can finally look at Trump with confidence and think: one of us.
www.theatlantic.com/ideas/archiv...
www.theatlantic.com/ideas/archiv...
Reposted by AccidentalPsychiatrist
I have covered presidential politics for 40 years. This was the most juvenile display by a President and Vice President I have ever seen. Other presidents treated their enemies with more respect. This is a low point and a dark day for the US. Totally embarrassing.
February 28, 2025 at 7:00 PM
I have covered presidential politics for 40 years. This was the most juvenile display by a President and Vice President I have ever seen. Other presidents treated their enemies with more respect. This is a low point and a dark day for the US. Totally embarrassing.
Reposted by AccidentalPsychiatrist
the old joke
interviewer: can you explain this year long gap in employment?
candidate: Twitter
interviewer you worked at Twitter?
candidate: No
interviewer: can you explain this year long gap in employment?
candidate: Twitter
interviewer you worked at Twitter?
candidate: No
February 28, 2025 at 5:35 PM
the old joke
interviewer: can you explain this year long gap in employment?
candidate: Twitter
interviewer you worked at Twitter?
candidate: No
interviewer: can you explain this year long gap in employment?
candidate: Twitter
interviewer you worked at Twitter?
candidate: No
Reposted by AccidentalPsychiatrist
These morons fired people who protect nuclear weapons without thinking about it. Thank you, Trump voters.
Trump administration wants to un-fire nuclear safety workers but can’t figure out how to reach them
www.nbcnews.com/politics/nat...
www.nbcnews.com/politics/nat...
Trump administration wants to un-fire nuclear safety workers but can’t figure out how to reach them
The individuals, who work in an agency that oversees the nation's nuclear stockpile, had been fired on Thursday and lost access to their federal government email accounts.
www.nbcnews.com
February 15, 2025 at 7:42 PM
These morons fired people who protect nuclear weapons without thinking about it. Thank you, Trump voters.
Reposted by AccidentalPsychiatrist
Reposted by AccidentalPsychiatrist
Mania speeds up the sense of time, while #depression slows it down.
The result: people with #bipolar to overestimate passage of time in mania (and underestimate in depression), concludes new review:
pubmed.ncbi.nlm.nih.gov/39846127
#psychiatry #pmhnp #bipolardisorder #psychology
The result: people with #bipolar to overestimate passage of time in mania (and underestimate in depression), concludes new review:
pubmed.ncbi.nlm.nih.gov/39846127
#psychiatry #pmhnp #bipolardisorder #psychology
February 15, 2025 at 4:39 PM
Mania speeds up the sense of time, while #depression slows it down.
The result: people with #bipolar to overestimate passage of time in mania (and underestimate in depression), concludes new review:
pubmed.ncbi.nlm.nih.gov/39846127
#psychiatry #pmhnp #bipolardisorder #psychology
The result: people with #bipolar to overestimate passage of time in mania (and underestimate in depression), concludes new review:
pubmed.ncbi.nlm.nih.gov/39846127
#psychiatry #pmhnp #bipolardisorder #psychology
Reposted by AccidentalPsychiatrist
when will yale law school answer for its sins
February 10, 2025 at 7:28 PM
when will yale law school answer for its sins
Reposted by AccidentalPsychiatrist
Antipsychotics with D3 partial agonism ranked by efficacy in #depression (ABC!):
1. Aripiprazole
2. Brexpiprazole
3. Cariprazine
pubmed.ncbi.nlm.nih.gov/38639435
Optimal doses in graph. I agree, but pure D3 agonist pramipexole works with less medical/neuro risk.
#psychiatry #pmhnp #mentalhealth
1. Aripiprazole
2. Brexpiprazole
3. Cariprazine
pubmed.ncbi.nlm.nih.gov/38639435
Optimal doses in graph. I agree, but pure D3 agonist pramipexole works with less medical/neuro risk.
#psychiatry #pmhnp #mentalhealth
December 24, 2024 at 12:23 AM
Antipsychotics with D3 partial agonism ranked by efficacy in #depression (ABC!):
1. Aripiprazole
2. Brexpiprazole
3. Cariprazine
pubmed.ncbi.nlm.nih.gov/38639435
Optimal doses in graph. I agree, but pure D3 agonist pramipexole works with less medical/neuro risk.
#psychiatry #pmhnp #mentalhealth
1. Aripiprazole
2. Brexpiprazole
3. Cariprazine
pubmed.ncbi.nlm.nih.gov/38639435
Optimal doses in graph. I agree, but pure D3 agonist pramipexole works with less medical/neuro risk.
#psychiatry #pmhnp #mentalhealth
Reposted by AccidentalPsychiatrist
Pindolol is the only med w/ controlled-evidence in treatment-resistant #panic. That trial was small and 25 yr old, so nice to see it revisited in this case report (2.5mg TID):
www.psychiatrist.com/pcc/pindolol...
Learn more in TR-#anxiety podcast
www.thecarlatreport.com/blogs/2-the-...
#psychiatry
www.psychiatrist.com/pcc/pindolol...
Learn more in TR-#anxiety podcast
www.thecarlatreport.com/blogs/2-the-...
#psychiatry
December 22, 2024 at 5:21 PM
Pindolol is the only med w/ controlled-evidence in treatment-resistant #panic. That trial was small and 25 yr old, so nice to see it revisited in this case report (2.5mg TID):
www.psychiatrist.com/pcc/pindolol...
Learn more in TR-#anxiety podcast
www.thecarlatreport.com/blogs/2-the-...
#psychiatry
www.psychiatrist.com/pcc/pindolol...
Learn more in TR-#anxiety podcast
www.thecarlatreport.com/blogs/2-the-...
#psychiatry
Reposted by AccidentalPsychiatrist
Do antidepressants augment mood stabilizers in #bipolar #depression? Yes, but benefit is very small (effect size=0.2 in this analysis):
pubmed.ncbi.nlm.nih.gov/38056138
Weigh that against risks (rapid cycling, mania, mixity), and they are a far cry from first line in #bipolardisorder
#psychiatry
pubmed.ncbi.nlm.nih.gov/38056138
Weigh that against risks (rapid cycling, mania, mixity), and they are a far cry from first line in #bipolardisorder
#psychiatry
December 19, 2024 at 10:08 PM
Do antidepressants augment mood stabilizers in #bipolar #depression? Yes, but benefit is very small (effect size=0.2 in this analysis):
pubmed.ncbi.nlm.nih.gov/38056138
Weigh that against risks (rapid cycling, mania, mixity), and they are a far cry from first line in #bipolardisorder
#psychiatry
pubmed.ncbi.nlm.nih.gov/38056138
Weigh that against risks (rapid cycling, mania, mixity), and they are a far cry from first line in #bipolardisorder
#psychiatry
Reposted by AccidentalPsychiatrist
Some high stats from the US:
> 1 in 4 women and 1 in 10 men have sought treatment for #depression
statista.com/statistics/1...
This reflects treatment seeking, not necessarily medication taking.
#psychiatry #bipolar #mentalhealth #psychology
> 1 in 4 women and 1 in 10 men have sought treatment for #depression
statista.com/statistics/1...
This reflects treatment seeking, not necessarily medication taking.
#psychiatry #bipolar #mentalhealth #psychology
December 18, 2024 at 7:05 PM
Some high stats from the US:
> 1 in 4 women and 1 in 10 men have sought treatment for #depression
statista.com/statistics/1...
This reflects treatment seeking, not necessarily medication taking.
#psychiatry #bipolar #mentalhealth #psychology
> 1 in 4 women and 1 in 10 men have sought treatment for #depression
statista.com/statistics/1...
This reflects treatment seeking, not necessarily medication taking.
#psychiatry #bipolar #mentalhealth #psychology
Reposted by AccidentalPsychiatrist
Metaanalysis of meds in #bulimia finds few winners. Topiramate looks good, along with the FDA-approved fluoxetine (Prozac, 60mg)
pubmed.ncbi.nlm.nih.gov/38042827
Topiramate dose = 100-200mg, sometimes 600, start 25mg/d and raise slowly every 7 days
#psychiatry #eatingdisorders
pubmed.ncbi.nlm.nih.gov/38042827
Topiramate dose = 100-200mg, sometimes 600, start 25mg/d and raise slowly every 7 days
#psychiatry #eatingdisorders
December 16, 2024 at 12:51 AM
Metaanalysis of meds in #bulimia finds few winners. Topiramate looks good, along with the FDA-approved fluoxetine (Prozac, 60mg)
pubmed.ncbi.nlm.nih.gov/38042827
Topiramate dose = 100-200mg, sometimes 600, start 25mg/d and raise slowly every 7 days
#psychiatry #eatingdisorders
pubmed.ncbi.nlm.nih.gov/38042827
Topiramate dose = 100-200mg, sometimes 600, start 25mg/d and raise slowly every 7 days
#psychiatry #eatingdisorders
Reposted by AccidentalPsychiatrist
Childhood #ADHD can turn into #schizophrenia, and this study of 211,705 identifies who is at risk. Those with multiple comorbidities, particularly #autism, intellectual disability, tics, #depression, and #bipolar
pubmed.ncbi.nlm.nih.gov/38032637
Stimulants and psychosis don't mix
pubmed.ncbi.nlm.nih.gov/38032637
Stimulants and psychosis don't mix
December 12, 2024 at 4:42 AM
Childhood #ADHD can turn into #schizophrenia, and this study of 211,705 identifies who is at risk. Those with multiple comorbidities, particularly #autism, intellectual disability, tics, #depression, and #bipolar
pubmed.ncbi.nlm.nih.gov/38032637
Stimulants and psychosis don't mix
pubmed.ncbi.nlm.nih.gov/38032637
Stimulants and psychosis don't mix
Reposted by AccidentalPsychiatrist
someBODY
once told me
luigi mangione
once told me
luigi mangione
December 11, 2024 at 2:43 AM
someBODY
once told me
luigi mangione
once told me
luigi mangione
Reposted by AccidentalPsychiatrist
How does ECT compare to TMS in depression?
2.5x higher response rates (38% vs 15%) in crossover study of 138 patients (each pt got both treatments):
pubmed.ncbi.nlm.nih.gov/38048154
#ECT (but not #TMS) is particularly effective for psychotic #depression.
#psychiatry #mentalhealth
2.5x higher response rates (38% vs 15%) in crossover study of 138 patients (each pt got both treatments):
pubmed.ncbi.nlm.nih.gov/38048154
#ECT (but not #TMS) is particularly effective for psychotic #depression.
#psychiatry #mentalhealth
December 11, 2024 at 3:54 AM
How does ECT compare to TMS in depression?
2.5x higher response rates (38% vs 15%) in crossover study of 138 patients (each pt got both treatments):
pubmed.ncbi.nlm.nih.gov/38048154
#ECT (but not #TMS) is particularly effective for psychotic #depression.
#psychiatry #mentalhealth
2.5x higher response rates (38% vs 15%) in crossover study of 138 patients (each pt got both treatments):
pubmed.ncbi.nlm.nih.gov/38048154
#ECT (but not #TMS) is particularly effective for psychotic #depression.
#psychiatry #mentalhealth
Reposted by AccidentalPsychiatrist
Tea improves #depression, cognition, #anxiety, #sleep through
> L-theanine, GABA, arginine, catechins, theaflavins, theacrine
#Tea is an antioxidant, neuroprotective, monoaminergic, microbiome-boosting, #stress hormone-regulating brain superfood. From:
pubmed.ncbi.nlm.nih.gov/39593401
> L-theanine, GABA, arginine, catechins, theaflavins, theacrine
#Tea is an antioxidant, neuroprotective, monoaminergic, microbiome-boosting, #stress hormone-regulating brain superfood. From:
pubmed.ncbi.nlm.nih.gov/39593401
December 11, 2024 at 3:56 AM
Tea improves #depression, cognition, #anxiety, #sleep through
> L-theanine, GABA, arginine, catechins, theaflavins, theacrine
#Tea is an antioxidant, neuroprotective, monoaminergic, microbiome-boosting, #stress hormone-regulating brain superfood. From:
pubmed.ncbi.nlm.nih.gov/39593401
> L-theanine, GABA, arginine, catechins, theaflavins, theacrine
#Tea is an antioxidant, neuroprotective, monoaminergic, microbiome-boosting, #stress hormone-regulating brain superfood. From:
pubmed.ncbi.nlm.nih.gov/39593401
Reposted by AccidentalPsychiatrist
Hey, my speciality is personality disorders and that can definitely be a sign, but there’s also other factors such as unstable relationships, lack of self, and self harm. Get properly diagnosed, there are good treatments for it.
December 7, 2024 at 10:43 PM
Hey, my speciality is personality disorders and that can definitely be a sign, but there’s also other factors such as unstable relationships, lack of self, and self harm. Get properly diagnosed, there are good treatments for it.
Reposted by AccidentalPsychiatrist
It took the NYPD three days to find the backpack left within walking distance of the shooting
December 7, 2024 at 12:43 AM
It took the NYPD three days to find the backpack left within walking distance of the shooting