Abigail Mackey
@abigailmackey1.bsky.social
Clinical Professor of Muscle Physiology and Regeneration after Traumatic Soft-tissue Injury @ismcopenhagen.bsky.social
https://orcid.org/0000-0002-2017-4580
#MyoBlue
https://orcid.org/0000-0002-2017-4580
#MyoBlue
Pinned
Our 2026 PhD course is now open for registration🤩
@ismcopenhagen.bsky.social
Copenhagen, 5-7 October 2026
Musculoskeletal tissue regeneration – mechanisms and clinical perspectives
Exciting topics and expert teachers - come join us!
phdcourses.ku.dk/DetailKursus...
@ismcopenhagen.bsky.social
Copenhagen, 5-7 October 2026
Musculoskeletal tissue regeneration – mechanisms and clinical perspectives
Exciting topics and expert teachers - come join us!
phdcourses.ku.dk/DetailKursus...
Reposted by Abigail Mackey
Big congrats to Max Ravn Merkel who successfully defended his PhD today on the topic of tendinopathy, backed by a strong team of supervisors and challenged by sharp opponents Profs Paul Ackermann 🇸🇪 and Jess Snedeker🇨🇭
🙌🥳🙌
🙌🥳🙌
January 7, 2026 at 6:32 PM
Big congrats to Max Ravn Merkel who successfully defended his PhD today on the topic of tendinopathy, backed by a strong team of supervisors and challenged by sharp opponents Profs Paul Ackermann 🇸🇪 and Jess Snedeker🇨🇭
🙌🥳🙌
🙌🥳🙌
Reposted by Abigail Mackey
Spinal motor neurons in dazzling detail. ✨
Each green dot is a spinal motor neuron - crucial but rare cells making up just 1% of neurons in the spinal cord. In diseases like ALS, they are selectively damaged, making them of special interest to neuroscientists.
#neuroskyence #FluorescenceFriday
Each green dot is a spinal motor neuron - crucial but rare cells making up just 1% of neurons in the spinal cord. In diseases like ALS, they are selectively damaged, making them of special interest to neuroscientists.
#neuroskyence #FluorescenceFriday
December 12, 2025 at 6:19 PM
Spinal motor neurons in dazzling detail. ✨
Each green dot is a spinal motor neuron - crucial but rare cells making up just 1% of neurons in the spinal cord. In diseases like ALS, they are selectively damaged, making them of special interest to neuroscientists.
#neuroskyence #FluorescenceFriday
Each green dot is a spinal motor neuron - crucial but rare cells making up just 1% of neurons in the spinal cord. In diseases like ALS, they are selectively damaged, making them of special interest to neuroscientists.
#neuroskyence #FluorescenceFriday
Reposted by Abigail Mackey
🚨This morning’s good news is that Max Merkel’s paper Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response is now online! 🥳🎅🎄
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response
Human participants with early- or chronic-stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are....
advanced.onlinelibrary.wiley.com
December 13, 2025 at 6:27 AM
🚨This morning’s good news is that Max Merkel’s paper Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response is now online! 🥳🎅🎄
advanced.onlinelibrary.wiley.com/doi/10.1002/...
advanced.onlinelibrary.wiley.com/doi/10.1002/...
💪🧠Thrilled to be awarded this grant to study how exercise supports the motoneurone-muscle interaction during ageing - with awesome collaborators @kevinmurachphd.bsky.social and Kristine Freude
@ismcopenhagen.bsky.social
🙏@lundbeckfonden.bsky.social
lundbeckfonden.com/en/exercise-...
@ismcopenhagen.bsky.social
🙏@lundbeckfonden.bsky.social
lundbeckfonden.com/en/exercise-...
Exercise to maintain and repair the ageing motoneurone-muscle axis
Has received a Professorship grant of DKK 20,000,000 from the Lundbeck Foundation.
lundbeckfonden.com
December 8, 2025 at 2:08 PM
💪🧠Thrilled to be awarded this grant to study how exercise supports the motoneurone-muscle interaction during ageing - with awesome collaborators @kevinmurachphd.bsky.social and Kristine Freude
@ismcopenhagen.bsky.social
🙏@lundbeckfonden.bsky.social
lundbeckfonden.com/en/exercise-...
@ismcopenhagen.bsky.social
🙏@lundbeckfonden.bsky.social
lundbeckfonden.com/en/exercise-...
Reposted by Abigail Mackey
📣Latest from the PowerLab 🚨
journals.physiology.org/doi/abs/10.1...
In this study we show that Eccentric overload training provided a more robust stimulus for longitudinal muscle remodelling than conventional resistance training.
journals.physiology.org/doi/abs/10.1...
In this study we show that Eccentric overload training provided a more robust stimulus for longitudinal muscle remodelling than conventional resistance training.
December 5, 2025 at 3:35 PM
📣Latest from the PowerLab 🚨
journals.physiology.org/doi/abs/10.1...
In this study we show that Eccentric overload training provided a more robust stimulus for longitudinal muscle remodelling than conventional resistance training.
journals.physiology.org/doi/abs/10.1...
In this study we show that Eccentric overload training provided a more robust stimulus for longitudinal muscle remodelling than conventional resistance training.
Reposted by Abigail Mackey
Big Bones Mean Big Muscles: An MRI-Based Dataset of Muscle-Bone-Body Size Relationships Across 70 Human Muscles of the Upper Limb, Trunk, and Lower Limb
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
Big Bones Mean Big Muscles: An MRI-Based Dataset of Muscle-Bone-Body Size Relationships Across 70 Human Muscles of the Upper Limb, Trunk, and Lower Limb | Journal of Applied Physiology | American Phys...
Body sizes and shapes vary widely, even among healthy adults, resulting in diverse muscle sizes, strengths, and performance capacities. This study developed an AI (artificially intelligent) algorithm ...
journals.physiology.org
December 5, 2025 at 6:13 PM
Big Bones Mean Big Muscles: An MRI-Based Dataset of Muscle-Bone-Body Size Relationships Across 70 Human Muscles of the Upper Limb, Trunk, and Lower Limb
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
Reposted by Abigail Mackey
Allison M. Owen et al. present this #TopicalReview examining therapeutic and pathological actions for fibro-adipogenic progenitors following #musculoskeletal injury 🏋️ 🔬
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
December 4, 2025 at 2:04 PM
Allison M. Owen et al. present this #TopicalReview examining therapeutic and pathological actions for fibro-adipogenic progenitors following #musculoskeletal injury 🏋️ 🔬
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
This was a fun team effort with @grithhojfeldt.bsky.social Christian Hoegsbjerg, Arvind von Keudell👏 covering the full spectrum of human skeletal muscle regenerative capacity 💪 from sports🏃♀️to trauma 🏥 settings. Lots more work to do in this field!
@ismcopenhagen.bsky.social
@ismcopenhagen.bsky.social
December 5, 2025 at 5:40 PM
This was a fun team effort with @grithhojfeldt.bsky.social Christian Hoegsbjerg, Arvind von Keudell👏 covering the full spectrum of human skeletal muscle regenerative capacity 💪 from sports🏃♀️to trauma 🏥 settings. Lots more work to do in this field!
@ismcopenhagen.bsky.social
@ismcopenhagen.bsky.social
Reposted by Abigail Mackey
Yesterday, Christian Couppé defended his doctorate of medical science (DMSc) investigating the Effects of Loading on Human Tendon in Health & Disease. Big thanks to the opponents Taija Finni & @larslandersen.bsky.social, chair Per Hölmich, & Jørn Wulff Helge for leading the ceremony 🥳 Congrats!
November 29, 2025 at 7:05 AM
Yesterday, Christian Couppé defended his doctorate of medical science (DMSc) investigating the Effects of Loading on Human Tendon in Health & Disease. Big thanks to the opponents Taija Finni & @larslandersen.bsky.social, chair Per Hölmich, & Jørn Wulff Helge for leading the ceremony 🥳 Congrats!
Reposted by Abigail Mackey
Two guest lecturers today! Håvard Visnes and Taija Finni give us new perspectives on the treatment of tendon ruptures, tendinopathy and ACL injuries.
November 27, 2025 at 5:32 PM
Two guest lecturers today! Håvard Visnes and Taija Finni give us new perspectives on the treatment of tendon ruptures, tendinopathy and ACL injuries.
In the snowy north❄️🇫🇮 today presenting our work on muscle memory in ageing and tissue injury, and learning about inter-individual variation🧠 Thank you Juha Ahtiainen and Mike Roberts for the invitation to this very interesting meeting🙏 Great to see old and new friends too🤗
@ismcopenhagen.bsky.social
@ismcopenhagen.bsky.social
November 20, 2025 at 2:34 PM
In the snowy north❄️🇫🇮 today presenting our work on muscle memory in ageing and tissue injury, and learning about inter-individual variation🧠 Thank you Juha Ahtiainen and Mike Roberts for the invitation to this very interesting meeting🙏 Great to see old and new friends too🤗
@ismcopenhagen.bsky.social
@ismcopenhagen.bsky.social
Reposted by Abigail Mackey
Our review on all things muscle in CP is now published in Dev Med Child Neurology. Massive effort by Sebastian Edman with great support from Eva Ponten, Sudarshan Dayanidhi and @ferdinandvw.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy
Cerebral palsy, caused by non-progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellul...
onlinelibrary.wiley.com
November 15, 2025 at 10:33 AM
Our review on all things muscle in CP is now published in Dev Med Child Neurology. Massive effort by Sebastian Edman with great support from Eva Ponten, Sudarshan Dayanidhi and @ferdinandvw.bsky.social
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Abigail Mackey
New results presented at this morning's meeting by Birgitte Hougs Kjær from her impressive #PASEtrial testing treatment options for patients with chronic rotator cuff tendinopathy👏👏
November 13, 2025 at 4:57 PM
New results presented at this morning's meeting by Birgitte Hougs Kjær from her impressive #PASEtrial testing treatment options for patients with chronic rotator cuff tendinopathy👏👏
Reposted by Abigail Mackey
Recruiting a comp PDRA for the lab 🚨
Working on multiple projects using integrated multi omics in bulk & single cell level
Passion for data, coding, bioinformatics & keen to lead our labs comp workflow
12 months in first instance but extendable for further 19 months
my.corehr.com/pls/coreport...
Working on multiple projects using integrated multi omics in bulk & single cell level
Passion for data, coding, bioinformatics & keen to lead our labs comp workflow
12 months in first instance but extendable for further 19 months
my.corehr.com/pls/coreport...
my.corehr.com
November 10, 2025 at 5:23 PM
Recruiting a comp PDRA for the lab 🚨
Working on multiple projects using integrated multi omics in bulk & single cell level
Passion for data, coding, bioinformatics & keen to lead our labs comp workflow
12 months in first instance but extendable for further 19 months
my.corehr.com/pls/coreport...
Working on multiple projects using integrated multi omics in bulk & single cell level
Passion for data, coding, bioinformatics & keen to lead our labs comp workflow
12 months in first instance but extendable for further 19 months
my.corehr.com/pls/coreport...
Reposted by Abigail Mackey
Day 2 of the Matrix Biology PhD course and we’re in the new Fælleshuset building starting our group work brain storming. Thanks to @douglaspdyer.bsky.social and @tranejoan.bsky.social for laying the foundations of ECM biology in yesterday’s lectures!
November 6, 2025 at 7:54 AM
Day 2 of the Matrix Biology PhD course and we’re in the new Fælleshuset building starting our group work brain storming. Thanks to @douglaspdyer.bsky.social and @tranejoan.bsky.social for laying the foundations of ECM biology in yesterday’s lectures!
Reposted by Abigail Mackey
Upcoming Postdoc Position! With Chris Nelson’s lab at U of A, we are looking for a fully supported 2-year postdoc to work on muscle gene editing and detection of gene doping in vivo. If interested, email myself and Chris: kmurach@uark.edu and nelsonc@uark.edu #myoblue
November 5, 2025 at 3:06 PM
Upcoming Postdoc Position! With Chris Nelson’s lab at U of A, we are looking for a fully supported 2-year postdoc to work on muscle gene editing and detection of gene doping in vivo. If interested, email myself and Chris: kmurach@uark.edu and nelsonc@uark.edu #myoblue
Reposted by Abigail Mackey
New month, new mesh! 🕸️🍂October newsletter is out; Latest on career opportunities, publications, upcoming events, initiatives💥A spotlight interview with P. Rosales that explores how funding cuts affects researchers📝Plus our monthly poll🗳️
November 4, 2025 at 11:51 AM
New month, new mesh! 🕸️🍂October newsletter is out; Latest on career opportunities, publications, upcoming events, initiatives💥A spotlight interview with P. Rosales that explores how funding cuts affects researchers📝Plus our monthly poll🗳️
Reposted by Abigail Mackey
Top Cited Review Article: Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
Michael D. Roberts, et al.
https://ow.ly/moMh50Xe5nU
#hypertrophy #myofiber
Michael D. Roberts, et al.
https://ow.ly/moMh50Xe5nU
#hypertrophy #myofiber
October 31, 2025 at 5:00 PM
Top Cited Review Article: Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
Michael D. Roberts, et al.
https://ow.ly/moMh50Xe5nU
#hypertrophy #myofiber
Michael D. Roberts, et al.
https://ow.ly/moMh50Xe5nU
#hypertrophy #myofiber
Reposted by Abigail Mackey
A heavy lift from a literal strongman, PhD candidate PJ Koopmans “The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus” 💪🏻 www.biorxiv.org/content/10.1...
www.biorxiv.org
October 30, 2025 at 11:16 AM
A heavy lift from a literal strongman, PhD candidate PJ Koopmans “The Age-Dependent Resident Myonuclear Multi-Omic Response to a Skeletal Muscle Hypertrophic Stimulus” 💪🏻 www.biorxiv.org/content/10.1...
Reposted by Abigail Mackey
Our tendon enthusiasts @ccstorytime.bsky.social & @annesofieagergaard.bsky.social are in Nanjing, China for an international meeting focused on orthopedic surgery and sports medicine talking about their approach with circadian rhythms and exercise-based treatment on tackling tendinopathy ⏰🏋️♀️ #tendon
October 31, 2025 at 5:17 AM
Our tendon enthusiasts @ccstorytime.bsky.social & @annesofieagergaard.bsky.social are in Nanjing, China for an international meeting focused on orthopedic surgery and sports medicine talking about their approach with circadian rhythms and exercise-based treatment on tackling tendinopathy ⏰🏋️♀️ #tendon
Reposted by Abigail Mackey
Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28...
@jphysiol.bsky.social
@jphysiol.bsky.social
NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training-induced changes in muscle morphology, function and gene networks relative to placebo ingestion...
doi.org
October 27, 2025 at 2:10 PM
Hopefully of interest to scientists and exercise practitioners with and interest in muscle mass and functional gains in human volunteers. doi.org/10.1113/JP28...
@jphysiol.bsky.social
@jphysiol.bsky.social
Reposted by Abigail Mackey
Manuscript now accepted! 🥳 @steffendanielle.bsky.social @valerioizzi.bsky.social @abigailmackey1.bsky.social @ismcopenhagen.bsky.social
Spatially distinct ECM-producing fibroblasts and myonuclei orchestrate early adaptation to mechanical loading in the human muscle-tendon unit
Spatially distinct ECM-producing fibroblasts and myonuclei orchestrate early adaptation to mechanical loading in the human muscle-tendon unit
October 15, 2025 at 3:59 PM
Manuscript now accepted! 🥳 @steffendanielle.bsky.social @valerioizzi.bsky.social @abigailmackey1.bsky.social @ismcopenhagen.bsky.social
Spatially distinct ECM-producing fibroblasts and myonuclei orchestrate early adaptation to mechanical loading in the human muscle-tendon unit
Spatially distinct ECM-producing fibroblasts and myonuclei orchestrate early adaptation to mechanical loading in the human muscle-tendon unit
Reposted by Abigail Mackey
From the team, Bjørk Wulff West Helge & Kenneth Mertz presented data from our studies on ultrarunners & bodybuilders show the impact of extreme training volume and severe energy restriction 🏃♀️💪 (2/2)
October 13, 2025 at 8:04 AM
From the team, Bjørk Wulff West Helge & Kenneth Mertz presented data from our studies on ultrarunners & bodybuilders show the impact of extreme training volume and severe energy restriction 🏃♀️💪 (2/2)
Reposted by Abigail Mackey
Some interesting data from postdoc Nate Serrano: “Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle” www.biorxiv.org/content/10.1...
Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle
Non-peripheral myonuclei are characteristic of skeletal muscle pathology and severe injury but also appear after exercise and with aging. Displaced myonuclei are typically attributed to the activity o...
www.biorxiv.org
October 12, 2025 at 11:50 AM
Some interesting data from postdoc Nate Serrano: “Displaced myonuclei are attributable to both resident myonuclear migration and stem cell fusion during mechanical loading in adult skeletal muscle” www.biorxiv.org/content/10.1...
Reposted by Abigail Mackey
Looking for a PhD ? Don’t miss ⬇️
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
October 4, 2025 at 9:31 AM
Looking for a PhD ? Don’t miss ⬇️
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases