EM doc | Resuscitationist | Medical Educator | EMRAP Managing Editor
He/Him/His
Instagram: @EMSwami
Anand Swaminathan is an Indian-American researcher and academic. He is the Robert C. Goizueta Chair of Organization and Management and Associate Dean of the Ph.D. program at the Emory University Goizueta School of Business. Previously, he held academic appointments at the University of Michigan School of Business and the University of California, Davis. .. more
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-Age-adjust(PMID: 24439717) + YEARS(PMID 28549662) incr threshold w/o incr miss rate
-Lancet Study(PMID: 41135553) simplifies: If PE isn’t most likely dx, double threshold
-0% miss rate w/ 19% decr CT
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-Large, midline vertical incision
-Palpate cricothyroid membrane w/ finger of nondominant hand
-Scalpel through membrane, drag laterally, flip and drag laterally
-Scalpel out, finger in
-Bougie in guided by finger
-6-0 ETT over bougie
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-HyperK
-Beta blocker/CCB tox (can occur outside overdose)
-Clonidine or digoxin tox
-Blood in belly (vagal stim)
-Neurogenic shock
-Severe hypothyroid
-HyperMg
-Inferior MI
-Advanced AV blocks
-BRASH Syndrome
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-paralysis: even 30 sec of apnea can drop pH precipitously
-paralysis duration after intubation won't allow overbreathing
-If pt truly tiring, pulling extra breaths from vent gonna be huge challenge
My exp: these pts do poorly w/ intubation. Check out this article: PMID: 26759664
-No diff 28d mortality
-Incr HD collapse w/ ketamine (driven by incr/new pressors)
-Not clear why (More aggressive resus in etomidate group?)
-Forces us to reconsider our induction agent choice
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Reposted by Anand Swaminathan
here’s what you need to know about medetomidine in the illicit opioid supply
LOV-ED (PMID: 28259481): decr in ARDS + vent assoc conditions w/ lung protective ventilation protocol in ED (14.7% to 7.3% NNT = 14)
Bottom Line: ED vent choices matter. TV 6-8 cc/kg IBW
+ titrate FiO2 + PEEP together
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#1: Full: Volume expansion
#2: Fast: Tachycardia helpful as increases cardiac output
#3: Squeezed: Use vasoactives to ensure adequate SVR + contractility (epi if bradycardic)
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PE should be strongly considered even if STEMI pattern
Avoid premature closure + consider alternative diagnoses
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Goal: mimic pre-intubation respiratory parameters
-Prior to intubation, pt tachypneic + hyperperpneic to blow down CO2
-Set RR high (may be 30+). Can get RR + TV off of NIV that you use for preox
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Classic signs/sx insenstitive: ~ 50% w/o HTN, ~15% w/ pulse deficit, 20% w/ normal CXR
Keys to make dx:
High risk features: family hx sudden death, connective tissue disorders
History: sudden/max/severe onset of pain
Sx above + below diaphragm
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Rx: Cefazolin 1 gm IV
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-Hyperperpnea drives CO2 down supporting pH
-Removing resp drive will drop pH ➡️ HD collapse
-Mech vent challenging as must mimic preintubation parameters
-Use NIV to support work of breathing instead
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-Long differential w/ some special considerations
-Unique: Uremic encephalopathy, dialysis disequilibrium syndrome, med accumulation
-More common: Electrolyte abnormalities, hypoglycemia, infections/sepsis, spontaneous ICH (poor plt fxn)
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Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
So tired of having this conversation
Reposted by Anand Swaminathan
Please step away from the FFP
EVERY guideline & article agrees that FFP shouldn't be given for pre-procedure coag optimization (even high-risk procedures)
Plt & fibrinogen are more controversial
Discussion emcrit.org/ibcc/cirrhos... #EMIMCC
-Focus resuscitative efforts on the mother. The better we resus mom, the better the outcome for both
-Access: 2 IV above the diaphragm
-Displace the uterus (Push to L lateral). Tilting can make resus more challenging
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It found a 68% reduction in suicidality for trans youth getting HRT.
It also found only 7 of more than 400 stopped taking HRT... and of those that did, 4 still identified as gender-diverse.
Transgender care saves lives.
Displacement, Obstruction, Patient factors (ie PE, PTX), Equipment Issues, Stacked Breaths.
Address all of these factors in parallel
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-Markedly lowers risk of getting COVID/Flu (doesn't eliminate completely)
-Reduces severity of illness
-Reduces likelihood of hospitalization in older, immunocompromised people
-Reduces the risk of transmission to others
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I wouldn’t do pushes but isotonic bicarbonate infusion would be great
-Restore volume, incr kidney perfusion leading to incr urine output + K elimination
-0.9% saline: pH 5.5, big Cl load. Worsen acidosis leading incr serum K
-LR superior: small amount of K in it won’t raise serum K. Won’t contribute to acidosis
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Reposted by Anand Swaminathan
This aligns nicely with recommendations from Canada's National Advisory Committee on Immunization. 🇨🇦
Link: tinyurl.com/yuwmmtt4 by Hansen et al.
We have octreotide which is very underwhelming
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Finer point: administration of metaclopramide + erythromycin
Promotility agents which help empty the stomach of blood, improve the view for endoscopist
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