🌟 Our research success!
The article about the record-breaking molecular photoswitch by Petr Kovaříček’s team (UCT Prague) and colleagues at IOCB Prague has been selected for the Most Popular Articles Collection of 2025 by the Journal of Materials Chemistry C! 🔬
The article about the record-breaking molecular photoswitch by Petr Kovaříček’s team (UCT Prague) and colleagues at IOCB Prague has been selected for the Most Popular Articles Collection of 2025 by the Journal of Materials Chemistry C! 🔬
January 12, 2026 at 9:26 AM
🌟 Our research success!
The article about the record-breaking molecular photoswitch by Petr Kovaříček’s team (UCT Prague) and colleagues at IOCB Prague has been selected for the Most Popular Articles Collection of 2025 by the Journal of Materials Chemistry C! 🔬
The article about the record-breaking molecular photoswitch by Petr Kovaříček’s team (UCT Prague) and colleagues at IOCB Prague has been selected for the Most Popular Articles Collection of 2025 by the Journal of Materials Chemistry C! 🔬
Thrilled to report another milestone: 900 nm photoswitching enables NIR-light detection and reversible invisible writing of high-contrast 2D and 3D displays! Check out our newest molecular photoswitch PBFT (peri-benzo[a]fluoranthenethioindigo) at ChemRxiv - doi.org/10.26434/che...
January 6, 2026 at 9:41 PM
Thrilled to report another milestone: 900 nm photoswitching enables NIR-light detection and reversible invisible writing of high-contrast 2D and 3D displays! Check out our newest molecular photoswitch PBFT (peri-benzo[a]fluoranthenethioindigo) at ChemRxiv - doi.org/10.26434/che...
#OPENACCESS: Cardiac action potential generation mechanisms via an intramembrane photoswitch. A simulation study. Ludovica Cestariolo, Chiara Florindi, Chiara Bertarelli, Antonio Zaza, Guglielmo Lanzani, Francesco Lodola, and Jose F. Rodriguez Matas. buff.ly/DGDX6Kr
Mechanically gated currents in mouse sensory neurons lacking PIEZO2
Touch sensation starts with the opening of mechanically gated activated ion channels at neuroglial endings of mechanoreceptors in the skin. The function of around half of low-threshold…
www.cell.com
December 30, 2025 at 3:02 PM
#OPENACCESS: Cardiac action potential generation mechanisms via an intramembrane photoswitch. A simulation study. Ludovica Cestariolo, Chiara Florindi, Chiara Bertarelli, Antonio Zaza, Guglielmo Lanzani, Francesco Lodola, and Jose F. Rodriguez Matas. buff.ly/DGDX6Kr
Hi! This is our first post on Bluesky, so we appreciate your help with a like and repost! Our team is thrilled to share our latest photoswitch work, revealing unique amino DASA features. Learn more, free of charge, at Chem. Sci.: pubs.rsc.org/en/content/articlelanding/2026/sc/d5sc07740k
December 16, 2025 at 5:49 PM
Hi! This is our first post on Bluesky, so we appreciate your help with a like and repost! Our team is thrilled to share our latest photoswitch work, revealing unique amino DASA features. Learn more, free of charge, at Chem. Sci.: pubs.rsc.org/en/content/articlelanding/2026/sc/d5sc07740k
Our new paper "A Versatile Strategy for Light-Driven Active Transport of Ions" is now online in @angewandtechemie.bsky.social!
shorturl.at/jr1wY
We used an azobenzene photoswitch to transport ions against their concentration gradients from one aqueous compartment to the other. This was achieved
shorturl.at/jr1wY
We used an azobenzene photoswitch to transport ions against their concentration gradients from one aqueous compartment to the other. This was achieved
December 10, 2025 at 10:43 AM
Our new paper "A Versatile Strategy for Light-Driven Active Transport of Ions" is now online in @angewandtechemie.bsky.social!
shorturl.at/jr1wY
We used an azobenzene photoswitch to transport ions against their concentration gradients from one aqueous compartment to the other. This was achieved
shorturl.at/jr1wY
We used an azobenzene photoswitch to transport ions against their concentration gradients from one aqueous compartment to the other. This was achieved
💡 Ready to light up your project?
Burkhard König et al. explain the important terminology and discuss the synthesis, switching mechanisms & properties of 7 #photoswitch classes. Check out the full tutorial review & start switching!
🔗 https://tinyurl.com/36tdmj92
@uniregensburg.bsky.social
#BJOC 💎🔓
Burkhard König et al. explain the important terminology and discuss the synthesis, switching mechanisms & properties of 7 #photoswitch classes. Check out the full tutorial review & start switching!
🔗 https://tinyurl.com/36tdmj92
@uniregensburg.bsky.social
#BJOC 💎🔓
November 27, 2025 at 2:02 PM
💡 Ready to light up your project?
Burkhard König et al. explain the important terminology and discuss the synthesis, switching mechanisms & properties of 7 #photoswitch classes. Check out the full tutorial review & start switching!
🔗 https://tinyurl.com/36tdmj92
@uniregensburg.bsky.social
#BJOC 💎🔓
Burkhard König et al. explain the important terminology and discuss the synthesis, switching mechanisms & properties of 7 #photoswitch classes. Check out the full tutorial review & start switching!
🔗 https://tinyurl.com/36tdmj92
@uniregensburg.bsky.social
#BJOC 💎🔓
📢Our team will be advertising a number of fully-funded positions in the coming months (new photoswitch-based projects)💡🚨 Applicants from the 🇪🇺 and 🇨🇳 are encouraged. More info will be coming soon and advertised on our website imineswitch.com
#photoswitch #imine
#photoswitch #imine
Greenfield Group — University of St Andrews
imineswitch.com
November 14, 2025 at 12:32 PM
📢Our team will be advertising a number of fully-funded positions in the coming months (new photoswitch-based projects)💡🚨 Applicants from the 🇪🇺 and 🇨🇳 are encouraged. More info will be coming soon and advertised on our website imineswitch.com
#photoswitch #imine
#photoswitch #imine
#OpenAccess article by Ronald K. Castellano 𝘦𝘵 𝘢𝘭.
#UniversityofFlorida #UF
The current work introduces a novel photoswitch system combining an electron-rich [2.2]pCp moiety with an electron-deficient RCN unit, as a planar chiral “push–pull” architecture.
🔗 doi.org/10.1039/D5QO01401H
#UniversityofFlorida #UF
The current work introduces a novel photoswitch system combining an electron-rich [2.2]pCp moiety with an electron-deficient RCN unit, as a planar chiral “push–pull” architecture.
🔗 doi.org/10.1039/D5QO01401H
[2.2]Paracyclophane–dicyanorhodanine conjugates as planar chiral molecular photoswitches
(Chir)optical molecular photoswitches have garnered significant attention for their applications in asymmetric synthesis, supramolecular chemistry, and the materials sciences. The planar chirality and...
doi.org
November 14, 2025 at 4:01 AM
#OpenAccess article by Ronald K. Castellano 𝘦𝘵 𝘢𝘭.
#UniversityofFlorida #UF
The current work introduces a novel photoswitch system combining an electron-rich [2.2]pCp moiety with an electron-deficient RCN unit, as a planar chiral “push–pull” architecture.
🔗 doi.org/10.1039/D5QO01401H
#UniversityofFlorida #UF
The current work introduces a novel photoswitch system combining an electron-rich [2.2]pCp moiety with an electron-deficient RCN unit, as a planar chiral “push–pull” architecture.
🔗 doi.org/10.1039/D5QO01401H
Re-ver-si-ble CPL inversion promoted by light and heat!
This collaborative work between the @feringalab.bsky.social and our group, the PulSAr team @univangers.bsky.social, is now online on ChemArXiv.
Special congrats to Louis and Eric!
chemrxiv.org/engage/chemr...
#motor #PDI #PBI #Photoswitch
This collaborative work between the @feringalab.bsky.social and our group, the PulSAr team @univangers.bsky.social, is now online on ChemArXiv.
Special congrats to Louis and Eric!
chemrxiv.org/engage/chemr...
#motor #PDI #PBI #Photoswitch
October 15, 2025 at 8:05 PM
Re-ver-si-ble CPL inversion promoted by light and heat!
This collaborative work between the @feringalab.bsky.social and our group, the PulSAr team @univangers.bsky.social, is now online on ChemArXiv.
Special congrats to Louis and Eric!
chemrxiv.org/engage/chemr...
#motor #PDI #PBI #Photoswitch
This collaborative work between the @feringalab.bsky.social and our group, the PulSAr team @univangers.bsky.social, is now online on ChemArXiv.
Special congrats to Louis and Eric!
chemrxiv.org/engage/chemr...
#motor #PDI #PBI #Photoswitch
🔦 Light Switch for Proteases💡
Controlling proteins with a light dimmer: This allows protein functions to be precisely modulated. Read more here 👉 doi.org/10.1039/D5CB00069F #Photoswitch #Photoresponsive #Taspase1 #ProteinManipulation
Controlling proteins with a light dimmer: This allows protein functions to be precisely modulated. Read more here 👉 doi.org/10.1039/D5CB00069F #Photoswitch #Photoresponsive #Taspase1 #ProteinManipulation
Photoresponsive molecular tweezers modulate Taspase 1 activity
Light serves as an exceptional stimulus for the precise spatiotemporal regulation of protein activity and protein–protein interactions. Here, we introduce a light-responsive supramolecular ligand syst...
doi.org
October 8, 2025 at 10:40 AM
🔦 Light Switch for Proteases💡
Controlling proteins with a light dimmer: This allows protein functions to be precisely modulated. Read more here 👉 doi.org/10.1039/D5CB00069F #Photoswitch #Photoresponsive #Taspase1 #ProteinManipulation
Controlling proteins with a light dimmer: This allows protein functions to be precisely modulated. Read more here 👉 doi.org/10.1039/D5CB00069F #Photoswitch #Photoresponsive #Taspase1 #ProteinManipulation
#research
How to (not) Evaluate a Photoswitch Performance; Benchmarking of Methods Used for Processing Kinetic Data on an Example of Arylazopyrazole Z-Isomer Half-Life (Hruzíková et al.)–ChemMethods: doi.org/10.1002/cmtd...
@iocbprague.bsky.social @chemistryeurope.bsky.social
How to (not) Evaluate a Photoswitch Performance; Benchmarking of Methods Used for Processing Kinetic Data on an Example of Arylazopyrazole Z-Isomer Half-Life (Hruzíková et al.)–ChemMethods: doi.org/10.1002/cmtd...
@iocbprague.bsky.social @chemistryeurope.bsky.social
October 6, 2025 at 1:25 PM
#research
How to (not) Evaluate a Photoswitch Performance; Benchmarking of Methods Used for Processing Kinetic Data on an Example of Arylazopyrazole Z-Isomer Half-Life (Hruzíková et al.)–ChemMethods: doi.org/10.1002/cmtd...
@iocbprague.bsky.social @chemistryeurope.bsky.social
How to (not) Evaluate a Photoswitch Performance; Benchmarking of Methods Used for Processing Kinetic Data on an Example of Arylazopyrazole Z-Isomer Half-Life (Hruzíková et al.)–ChemMethods: doi.org/10.1002/cmtd...
@iocbprague.bsky.social @chemistryeurope.bsky.social
New in Chemical Science!
"Aryl azopyrroles as visible light photoswitchable TRPA1 ligands" by Pui-Ying Lam (Medical College of Wisconsin) and Matthew Fuchter (Imperial College London, Oxford University) et al. @fuchtermatt.bsky.social
Read it here: doi.org/10.1039/D5SC...
"Aryl azopyrroles as visible light photoswitchable TRPA1 ligands" by Pui-Ying Lam (Medical College of Wisconsin) and Matthew Fuchter (Imperial College London, Oxford University) et al. @fuchtermatt.bsky.social
Read it here: doi.org/10.1039/D5SC...
October 2, 2025 at 3:42 PM
New in Chemical Science!
"Aryl azopyrroles as visible light photoswitchable TRPA1 ligands" by Pui-Ying Lam (Medical College of Wisconsin) and Matthew Fuchter (Imperial College London, Oxford University) et al. @fuchtermatt.bsky.social
Read it here: doi.org/10.1039/D5SC...
"Aryl azopyrroles as visible light photoswitchable TRPA1 ligands" by Pui-Ying Lam (Medical College of Wisconsin) and Matthew Fuchter (Imperial College London, Oxford University) et al. @fuchtermatt.bsky.social
Read it here: doi.org/10.1039/D5SC...
🔓Take a look in our Photoswitches & Photopharmacology collection at a #OpenAccess paper from Kimio Sumaru, Kingo Uchida & co. on using a diarylethene photoswitch for photo-controllable cytotoxicity in cell culture #orgchem
📍AIST, Ryukoku University
📍AIST, Ryukoku University
Photo-controllable cytotoxicity in cell culture using a diarylethene photoswitch
For diarylethene (DAE) derivatives, whose dark cytotoxicity varies greatly depending on their isomerization state, we observe that the non-toxic open-ring isomer taken up by cells is converted to a…
pubs.rsc.org
September 25, 2025 at 8:48 AM
🔓Take a look in our Photoswitches & Photopharmacology collection at a #OpenAccess paper from Kimio Sumaru, Kingo Uchida & co. on using a diarylethene photoswitch for photo-controllable cytotoxicity in cell culture #orgchem
📍AIST, Ryukoku University
📍AIST, Ryukoku University
🧲 Read: A research team has created and described a new type of photoswitch. The molecule, a thienyl-based acylhydrazone, undergoes an unprecedented "closed-to-open-shell" transformation, where light converts it into a stable diradical.
phys.org/news/2025-09...
phys.org/news/2025-09...
Chemists create light-switchable magnets that remain active for hours
A research team from the University of Chemistry and Technology, Prague (UCT Prague) and the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) has created…
phys.org
September 19, 2025 at 5:56 PM
🧲 Read: A research team has created and described a new type of photoswitch. The molecule, a thienyl-based acylhydrazone, undergoes an unprecedented "closed-to-open-shell" transformation, where light converts it into a stable diradical.
phys.org/news/2025-09...
phys.org/news/2025-09...
A Prague research team created a light‑activated molecule that stays magnetic for over six hours and can be produced for about 1,000 Czech crowns per kilogram. Read more: https://getnews.me/light-switchable-magnets-with-hours-long-magnetic-state-developed/ #photoswitch #magnetism
September 19, 2025 at 11:03 AM
A Prague research team created a light‑activated molecule that stays magnetic for over six hours and can be produced for about 1,000 Czech crowns per kilogram. Read more: https://getnews.me/light-switchable-magnets-with-hours-long-magnetic-state-developed/ #photoswitch #magnetism
🔬💡 Scientists from UCT Prague and IOCB have developed a photoswitch that rewrites the rules of photochemistry – its so-called triplet state lasts hours instead of milliseconds!
September 9, 2025 at 7:43 AM
🔬💡 Scientists from UCT Prague and IOCB have developed a photoswitch that rewrites the rules of photochemistry – its so-called triplet state lasts hours instead of milliseconds!
📢New perspective on light responsive imine-based systems out now in @chemicalscience.rsc.org with @jiarongwu.bsky.social 💡🚨🔦 This is part of the 2025 Leading Investigators Collection, Thank you to the reviewers for input 🙏 #hot #photoswitch #imine imineswitch.com
doi.org/10.1039/D5SC...
doi.org/10.1039/D5SC...
September 8, 2025 at 11:07 AM
📢New perspective on light responsive imine-based systems out now in @chemicalscience.rsc.org with @jiarongwu.bsky.social 💡🚨🔦 This is part of the 2025 Leading Investigators Collection, Thank you to the reviewers for input 🙏 #hot #photoswitch #imine imineswitch.com
doi.org/10.1039/D5SC...
doi.org/10.1039/D5SC...
Researchers use EOM-EA-CCSD in Q-Chem to study the chirality-induced spin-selectivity (CISS) effect in a chiral molecule that can also act as a photoswitch, providing useful fundamental insights into CISS: doi.org/10.1021/acs....
Try Q-Chem: q-chem.com/try/
Try Q-Chem: q-chem.com/try/
Ultrafast Transversal CISS Effect Observed in a Chiral Photoswitching Molecule
Progress in the fundamental understanding of the chirality-induced spin-selectivity (CISS) effect is hindered by complexity of the systems that have been characterized experimentally. With the goal of...
doi.org
September 3, 2025 at 9:40 PM
Researchers use EOM-EA-CCSD in Q-Chem to study the chirality-induced spin-selectivity (CISS) effect in a chiral molecule that can also act as a photoswitch, providing useful fundamental insights into CISS: doi.org/10.1021/acs....
Try Q-Chem: q-chem.com/try/
Try Q-Chem: q-chem.com/try/
The team rationally designed a bridged bicyclic diene (BBD) photoswitch, strategically introducing substituents to promote hydrogen bonding and electronic effects.
August 13, 2025 at 7:01 PM
The team rationally designed a bridged bicyclic diene (BBD) photoswitch, strategically introducing substituents to promote hydrogen bonding and electronic effects.
🎬 Episode 17 of #SpotOnScience is out!
In this episode, Jeannette Gebel from the Institute of Innate Immunity is talking about her recent publication about a novel photoswitch that can enhance gene expression in mammalian cells.
Now available on Youtube: www.youtube.com/watch?v=-yR_...
In this episode, Jeannette Gebel from the Institute of Innate Immunity is talking about her recent publication about a novel photoswitch that can enhance gene expression in mammalian cells.
Now available on Youtube: www.youtube.com/watch?v=-yR_...
Spot on Science, Episode#17, Jeannette Gebel / Optogenetic enhancement of protein bioproduction
YouTube video by Exzellenzcluster ImmunoSensation
www.youtube.com
August 12, 2025 at 8:19 AM
🎬 Episode 17 of #SpotOnScience is out!
In this episode, Jeannette Gebel from the Institute of Innate Immunity is talking about her recent publication about a novel photoswitch that can enhance gene expression in mammalian cells.
Now available on Youtube: www.youtube.com/watch?v=-yR_...
In this episode, Jeannette Gebel from the Institute of Innate Immunity is talking about her recent publication about a novel photoswitch that can enhance gene expression in mammalian cells.
Now available on Youtube: www.youtube.com/watch?v=-yR_...
This study investigates the photophysics of a rhodanine-based photoswitch using ultrafast spectroscopy and quantum chemical calculations. Contrary to closely related photoswitches, the rhodanine compound exhibits a complex, multi-state relaxation pathway.
August 8, 2025 at 10:59 AM
This study investigates the photophysics of a rhodanine-based photoswitch using ultrafast spectroscopy and quantum chemical calculations. Contrary to closely related photoswitches, the rhodanine compound exhibits a complex, multi-state relaxation pathway.
Uncover the complex photophysics of a rhodanine photoswitch - a promising molecule for photonics and pharmaceuticals. Discover an unexpected triplet-mediated isomerization pathway that ch...
🧵 Thread below
Full analysis: https://helixbrief.com/article/67927bc9-ca99-432a-9b51-31dd9b502855
🧵 Thread below
Full analysis: https://helixbrief.com/article/67927bc9-ca99-432a-9b51-31dd9b502855
August 8, 2025 at 10:59 AM
Uncover the complex photophysics of a rhodanine photoswitch - a promising molecule for photonics and pharmaceuticals. Discover an unexpected triplet-mediated isomerization pathway that ch...
🧵 Thread below
Full analysis: https://helixbrief.com/article/67927bc9-ca99-432a-9b51-31dd9b502855
🧵 Thread below
Full analysis: https://helixbrief.com/article/67927bc9-ca99-432a-9b51-31dd9b502855
🔓Don't miss the recent #OpenAccess article by Lauren Hatcher and colleagues at Cardiff University School of Chemistry and @diamondlightsource.bsky.social on Controlled microcrystallization for in situ photocrystallography: optimizing crystal size and habit.💎👇
🔗 doi.org/10.1039/D5CE... 🧪
🔗 doi.org/10.1039/D5CE... 🧪
July 23, 2025 at 3:53 PM
🔓Don't miss the recent #OpenAccess article by Lauren Hatcher and colleagues at Cardiff University School of Chemistry and @diamondlightsource.bsky.social on Controlled microcrystallization for in situ photocrystallography: optimizing crystal size and habit.💎👇
🔗 doi.org/10.1039/D5CE... 🧪
🔗 doi.org/10.1039/D5CE... 🧪
New featured paper from @moth-poulsen.bsky.social (@upc.edu):
New high-throughput platform for photoswitch charactarisation using UV-Vis, LEDs & Python. Cuts material use, boosts reproducibility. Validated several photoswitch classes. #chemistry #photoswitches #openscience
doi.org/10.1039/D5DD...
New high-throughput platform for photoswitch charactarisation using UV-Vis, LEDs & Python. Cuts material use, boosts reproducibility. Validated several photoswitch classes. #chemistry #photoswitches #openscience
doi.org/10.1039/D5DD...
July 11, 2025 at 9:23 AM
New featured paper from @moth-poulsen.bsky.social (@upc.edu):
New high-throughput platform for photoswitch charactarisation using UV-Vis, LEDs & Python. Cuts material use, boosts reproducibility. Validated several photoswitch classes. #chemistry #photoswitches #openscience
doi.org/10.1039/D5DD...
New high-throughput platform for photoswitch charactarisation using UV-Vis, LEDs & Python. Cuts material use, boosts reproducibility. Validated several photoswitch classes. #chemistry #photoswitches #openscience
doi.org/10.1039/D5DD...
This week’s #ChemSciPicks is "Stimuli-Responsive Photoswitch-Actinide Binding: A Match Made in MOFs" by @shustovalab.bsky.social (University of South Carolina, United States) et al.
Read the paper here for free: doi.org/10.1039/D5SC...
#ChemSky
Read the paper here for free: doi.org/10.1039/D5SC...
#ChemSky
July 10, 2025 at 9:00 AM
This week’s #ChemSciPicks is "Stimuli-Responsive Photoswitch-Actinide Binding: A Match Made in MOFs" by @shustovalab.bsky.social (University of South Carolina, United States) et al.
Read the paper here for free: doi.org/10.1039/D5SC...
#ChemSky
Read the paper here for free: doi.org/10.1039/D5SC...
#ChemSky