Chemical Science
@chemicalscience.rsc.org
Flagship journal for @rsc.org, open access with no publication fee, all topics in chemistry. chemicalscience-rsc@rsc.org
Celebrating our 15th year in 2025! 🌐 Website: rsc.li/chemscience
Celebrating our 15th year in 2025! 🌐 Website: rsc.li/chemscience
Professor Louise Berben (UC Davis) features in our latest Reviewer Spotlight. Find out what advice she has regarding reviewing and preparing a paper in our blogpost here: blogs.rsc.org/sc/202...
January 8, 2026 at 2:32 PM
Professor Louise Berben (UC Davis) features in our latest Reviewer Spotlight. Find out what advice she has regarding reviewing and preparing a paper in our blogpost here: blogs.rsc.org/sc/202...
Reposted by Chemical Science
New paper out in @chemicalscience.rsc.org. Collaboration with Anita Jones @edinburghchem.bsky.social and Byron Purse @byronpurse.bsky.social. Great work from Alix Bailie, Henry Sansom and Filippos Stefanou. @uofgchem.bsky.social doi.org/10.1039/D5SC...
Two-photon excitation enables single-molecule detection of a fluorescent base analogue in DNA with high photostability
Fluorescent modification of nucleic acids using nucleobase analogues provides unique capabilities for imaging nucleic acids in cells and monitoring their conformational changes upon interaction with o...
doi.org
January 7, 2026 at 3:23 PM
New paper out in @chemicalscience.rsc.org. Collaboration with Anita Jones @edinburghchem.bsky.social and Byron Purse @byronpurse.bsky.social. Great work from Alix Bailie, Henry Sansom and Filippos Stefanou. @uofgchem.bsky.social doi.org/10.1039/D5SC...
Reposted by Chemical Science
Excited to share our new @chemicalscience.rsc.org paper! We show that the fluorescent DNA base analogue ABN performs exceptionally under two-photon excitation, enabling single-molecule detection with >10× brightness vs other analogues and improved photostability. pubs.rsc.org/en/content/a...
Two-photon excitation enables single-molecule detection of a fluorescent base analogue in DNA with high photostability
Fluorescent modification of nucleic acids using nucleobase analogues provides unique capabilities for imaging nucleic acids in cells and monitoring their conformational changes upon interaction with o...
pubs.rsc.org
January 7, 2026 at 11:49 PM
Excited to share our new @chemicalscience.rsc.org paper! We show that the fluorescent DNA base analogue ABN performs exceptionally under two-photon excitation, enabling single-molecule detection with >10× brightness vs other analogues and improved photostability. pubs.rsc.org/en/content/a...
🔥 New and HOT in Chemical Science!
“Unveiling hydrogen-source-dominated CO2 electroreduction activity on nitrogen-doped carbon nanotubes” by Liu Deng, Shanyong Chen and You-Nian Liu et al. from Central South University and Hangzhou Normal University.
Read it for free here: doi.org/10.1039/D5SC...
“Unveiling hydrogen-source-dominated CO2 electroreduction activity on nitrogen-doped carbon nanotubes” by Liu Deng, Shanyong Chen and You-Nian Liu et al. from Central South University and Hangzhou Normal University.
Read it for free here: doi.org/10.1039/D5SC...
January 8, 2026 at 1:00 PM
🔥 New and HOT in Chemical Science!
“Unveiling hydrogen-source-dominated CO2 electroreduction activity on nitrogen-doped carbon nanotubes” by Liu Deng, Shanyong Chen and You-Nian Liu et al. from Central South University and Hangzhou Normal University.
Read it for free here: doi.org/10.1039/D5SC...
“Unveiling hydrogen-source-dominated CO2 electroreduction activity on nitrogen-doped carbon nanotubes” by Liu Deng, Shanyong Chen and You-Nian Liu et al. from Central South University and Hangzhou Normal University.
Read it for free here: doi.org/10.1039/D5SC...
🔥 New and HOT in Chemical Science!
“Interfacial polarization enables dual pathways for electrosynthesis of propyl acetate” by Yansong Zhou and Shuangyin Wang et al. from Hunan University.
Read it for free here: doi.org/10.1039/D5SC...
“Interfacial polarization enables dual pathways for electrosynthesis of propyl acetate” by Yansong Zhou and Shuangyin Wang et al. from Hunan University.
Read it for free here: doi.org/10.1039/D5SC...
January 7, 2026 at 1:00 PM
🔥 New and HOT in Chemical Science!
“Interfacial polarization enables dual pathways for electrosynthesis of propyl acetate” by Yansong Zhou and Shuangyin Wang et al. from Hunan University.
Read it for free here: doi.org/10.1039/D5SC...
“Interfacial polarization enables dual pathways for electrosynthesis of propyl acetate” by Yansong Zhou and Shuangyin Wang et al. from Hunan University.
Read it for free here: doi.org/10.1039/D5SC...
Reposted by Chemical Science
Have a look at the last work of @duncanbrownsey.bsky.social and Alexandre Schoepfer combining small rings and Pd catalysis for the stereoselective synthesis of spirocyclic cyclopropane-oxazolines just published @chemicalscience.rsc.org !
pubs.rsc.org/en/Content/A...
pubs.rsc.org/en/Content/A...
January 7, 2026 at 11:24 AM
Have a look at the last work of @duncanbrownsey.bsky.social and Alexandre Schoepfer combining small rings and Pd catalysis for the stereoselective synthesis of spirocyclic cyclopropane-oxazolines just published @chemicalscience.rsc.org !
pubs.rsc.org/en/Content/A...
pubs.rsc.org/en/Content/A...
Our Chemical Science Pick of the Week for this week is "High-yield Synthesis of Graphene Quantum Dots from Spent Graphite and Application in Hydrogel Zn Batteries" by Hongshuai Hou et al. from Central South University.
Read it for free here: doi.org/10.1039/D5SC...
Read it for free here: doi.org/10.1039/D5SC...
January 7, 2026 at 10:01 AM
Our Chemical Science Pick of the Week for this week is "High-yield Synthesis of Graphene Quantum Dots from Spent Graphite and Application in Hydrogel Zn Batteries" by Hongshuai Hou et al. from Central South University.
Read it for free here: doi.org/10.1039/D5SC...
Read it for free here: doi.org/10.1039/D5SC...
🔥 New and HOT in Chemical Science!
“Ultrafast spectroscopic signatures for off-to-on photoswitchable species in a green-to-red photoconvertible fluorescent protein” by Chong Fang et al. from Oregon State University.
Read it for free here: pubs.rsc.org/doi/D5S...
“Ultrafast spectroscopic signatures for off-to-on photoswitchable species in a green-to-red photoconvertible fluorescent protein” by Chong Fang et al. from Oregon State University.
Read it for free here: pubs.rsc.org/doi/D5S...
January 6, 2026 at 5:13 PM
🔥 New and HOT in Chemical Science!
“Ultrafast spectroscopic signatures for off-to-on photoswitchable species in a green-to-red photoconvertible fluorescent protein” by Chong Fang et al. from Oregon State University.
Read it for free here: pubs.rsc.org/doi/D5S...
“Ultrafast spectroscopic signatures for off-to-on photoswitchable species in a green-to-red photoconvertible fluorescent protein” by Chong Fang et al. from Oregon State University.
Read it for free here: pubs.rsc.org/doi/D5S...
🎄On the 12th day of Christmas, Nicholas Chilton and David Mills et al. gave to us, a paper on magnets!
“A fluorobenzene-bound dysprosium half-sandwich dication single-molecule magnet”
Read it for free here: doi.org/10.1039/D4SC...
“A fluorobenzene-bound dysprosium half-sandwich dication single-molecule magnet”
Read it for free here: doi.org/10.1039/D4SC...
January 5, 2026 at 1:00 PM
🎄On the 12th day of Christmas, Nicholas Chilton and David Mills et al. gave to us, a paper on magnets!
“A fluorobenzene-bound dysprosium half-sandwich dication single-molecule magnet”
Read it for free here: doi.org/10.1039/D4SC...
“A fluorobenzene-bound dysprosium half-sandwich dication single-molecule magnet”
Read it for free here: doi.org/10.1039/D4SC...
Reposted by Chemical Science
A researcher in the US has successfully modelled the complex crystal structures of axitinib, an anti-cancer drug whose multiple crystalline forms complicated its development path to FDA approval.
Crystal structure prediction reaches new heights with axitinib
Computational strategy predicts complex polymorphs and distinguishes salts from co-crystals
www.chemistryworld.com
December 9, 2025 at 12:00 PM
A researcher in the US has successfully modelled the complex crystal structures of axitinib, an anti-cancer drug whose multiple crystalline forms complicated its development path to FDA approval.
🎄On the 11th day of Christmas, Hai-Yan Hu, Yan-Fang Zhu, and Yao Zhao et al. gave to us, a paper on sodium!
“Periodic Law-Guided Design of Highly Stable O3-Type Layered Oxide Cathodes for Practical Sodium-Ion Batteries”
Read it for free here: doi.org/10.1039/D4SC...
“Periodic Law-Guided Design of Highly Stable O3-Type Layered Oxide Cathodes for Practical Sodium-Ion Batteries”
Read it for free here: doi.org/10.1039/D4SC...
January 4, 2026 at 1:00 PM
🎄On the 11th day of Christmas, Hai-Yan Hu, Yan-Fang Zhu, and Yao Zhao et al. gave to us, a paper on sodium!
“Periodic Law-Guided Design of Highly Stable O3-Type Layered Oxide Cathodes for Practical Sodium-Ion Batteries”
Read it for free here: doi.org/10.1039/D4SC...
“Periodic Law-Guided Design of Highly Stable O3-Type Layered Oxide Cathodes for Practical Sodium-Ion Batteries”
Read it for free here: doi.org/10.1039/D4SC...
🎄On the 10th day of Christmas, Erwin Reisner et al. gave to us, a paper on gases and light!
“Adapting gas fermenting bacteria for light-driven domino valorization of CO2”
Read it for free here: doi.org/10.1039/D5SC...
“Adapting gas fermenting bacteria for light-driven domino valorization of CO2”
Read it for free here: doi.org/10.1039/D5SC...
January 3, 2026 at 1:00 PM
🎄On the 10th day of Christmas, Erwin Reisner et al. gave to us, a paper on gases and light!
“Adapting gas fermenting bacteria for light-driven domino valorization of CO2”
Read it for free here: doi.org/10.1039/D5SC...
“Adapting gas fermenting bacteria for light-driven domino valorization of CO2”
Read it for free here: doi.org/10.1039/D5SC...
Our ChemSci Pick of the Week for this week is "Directing robust built-in electric fields via imine linkage orientation in COFs for efficient dehydrogenative organic transformation coupled with H2O2 photosynthesis" by Enwei Zhu, Yongfa Zhu and Chen Chen
Read it for free here: doi.org/10.1039/D5SC...
Read it for free here: doi.org/10.1039/D5SC...
January 3, 2026 at 10:00 AM
Our ChemSci Pick of the Week for this week is "Directing robust built-in electric fields via imine linkage orientation in COFs for efficient dehydrogenative organic transformation coupled with H2O2 photosynthesis" by Enwei Zhu, Yongfa Zhu and Chen Chen
Read it for free here: doi.org/10.1039/D5SC...
Read it for free here: doi.org/10.1039/D5SC...
🎄On the 9th day of Christmas, Yoichi Kobayashi et al. gave to us, a paper on fluorine!
“Photocatalytic defluorination of perfluoroalkyl substances by surface-engineered ZnO nanocrystals”
Read it for free here: doi.org/10.1039/D5SC...
“Photocatalytic defluorination of perfluoroalkyl substances by surface-engineered ZnO nanocrystals”
Read it for free here: doi.org/10.1039/D5SC...
January 2, 2026 at 1:57 PM
🎄On the 9th day of Christmas, Yoichi Kobayashi et al. gave to us, a paper on fluorine!
“Photocatalytic defluorination of perfluoroalkyl substances by surface-engineered ZnO nanocrystals”
Read it for free here: doi.org/10.1039/D5SC...
“Photocatalytic defluorination of perfluoroalkyl substances by surface-engineered ZnO nanocrystals”
Read it for free here: doi.org/10.1039/D5SC...
HNY from Chemical Science! We wish you all a successful and peaceful 2026!
Thank you to all of our readers, authors, and reviewers for making 2025 a huge success! We were delighted by the excellent papers in our 15th anniversary collections and we're excited for 2026!
#ChemSky #HNY #2026
Thank you to all of our readers, authors, and reviewers for making 2025 a huge success! We were delighted by the excellent papers in our 15th anniversary collections and we're excited for 2026!
#ChemSky #HNY #2026
January 2, 2026 at 11:00 AM
Reposted by Chemical Science
Unimolecular stimuli-responsive nanomaterials
Stable, biocompatible, & optically self-reporting nanomaterials printed in microstructures using a Nanoscribe two-photon system.
Kudos to the @sydney.edu.au & @uniheidelberg.bsky.social teams!
More: pubs.rsc.org/en/content/a...
Stable, biocompatible, & optically self-reporting nanomaterials printed in microstructures using a Nanoscribe two-photon system.
Kudos to the @sydney.edu.au & @uniheidelberg.bsky.social teams!
More: pubs.rsc.org/en/content/a...
A printable, unimolecular, core–shell polymer bottlebrush-based signal transducer using solvatochromatic reporting - Chemical Science (RSC Publishing) DOI:10.1039/D5SC07029E
Chenyou Zhang a, Samantha O. Catt b, Tom Hawtrey cde, Ping Zeng a, Haoxiang Zeng a, Simran D. Kerai a, Yen Theng Cheng a, Moritz P. Hopp b, Qinqin Yang a, Elizabeth J. New cde, Eva Blasco *b and…
pubs.rsc.org
December 29, 2025 at 12:01 PM
Unimolecular stimuli-responsive nanomaterials
Stable, biocompatible, & optically self-reporting nanomaterials printed in microstructures using a Nanoscribe two-photon system.
Kudos to the @sydney.edu.au & @uniheidelberg.bsky.social teams!
More: pubs.rsc.org/en/content/a...
Stable, biocompatible, & optically self-reporting nanomaterials printed in microstructures using a Nanoscribe two-photon system.
Kudos to the @sydney.edu.au & @uniheidelberg.bsky.social teams!
More: pubs.rsc.org/en/content/a...
Reposted by Chemical Science
📣Very nice Christmas present! Just published in @chemicalscience.rsc.org the result of a collaboration with J.J. Weigand in Dresden. we report the synthesis and mechanistic study of Cationic Phospha-Wittig reaction! 👇👏@dquimicauib.bsky.social @uib.cat
pubs.rsc.org/en/Content/A...
pubs.rsc.org/en/Content/A...
December 26, 2025 at 4:53 PM
📣Very nice Christmas present! Just published in @chemicalscience.rsc.org the result of a collaboration with J.J. Weigand in Dresden. we report the synthesis and mechanistic study of Cationic Phospha-Wittig reaction! 👇👏@dquimicauib.bsky.social @uib.cat
pubs.rsc.org/en/Content/A...
pubs.rsc.org/en/Content/A...
Reposted by Chemical Science
Happy to share that our research on rare 1D organometallic lanthanide chain compounds got highlighted on the Outside Back Cover 😎🥳😊! Thanks Chemical Science! Happy Holidays from the Demir Group 💚🤍!
Cover: pubs.rsc.org/en/content/a...
Paper: pubs.rsc.org/en/content/a...
@chemicalscience.rsc.org
Cover: pubs.rsc.org/en/content/a...
Paper: pubs.rsc.org/en/content/a...
@chemicalscience.rsc.org
December 28, 2025 at 8:17 AM
Happy to share that our research on rare 1D organometallic lanthanide chain compounds got highlighted on the Outside Back Cover 😎🥳😊! Thanks Chemical Science! Happy Holidays from the Demir Group 💚🤍!
Cover: pubs.rsc.org/en/content/a...
Paper: pubs.rsc.org/en/content/a...
@chemicalscience.rsc.org
Cover: pubs.rsc.org/en/content/a...
Paper: pubs.rsc.org/en/content/a...
@chemicalscience.rsc.org
Reposted by Chemical Science
Structural & electronic modulations of copper enzyme lytic polysaccharide monooxygenase upon chitin binding (via @chemicalscience.rsc.org)
doi.org/10.1039/D5SC...
doi.org/10.1039/D5SC...
Structural and electronic modulations of lytic polysaccharide monooxygenase (LPMO) upon chitin binding: insights from X-ray spectroscopy
Lytic polysaccharide monooxygenases (LPMOs) play a critical role in the depolymerization of recalcitrant polysaccharides, such as chitin, making them of interest in biotechnological applications. Thes...
doi.org
December 30, 2025 at 8:58 AM
Structural & electronic modulations of copper enzyme lytic polysaccharide monooxygenase upon chitin binding (via @chemicalscience.rsc.org)
doi.org/10.1039/D5SC...
doi.org/10.1039/D5SC...
Dr Sami Lakhdar (Centre National de la Recherche Scientifique, France) is highlighted in our Reviewer Spotlight! Find out more here: blogs.rsc.org/sc/202...
January 2, 2026 at 9:21 AM
Dr Sami Lakhdar (Centre National de la Recherche Scientifique, France) is highlighted in our Reviewer Spotlight! Find out more here: blogs.rsc.org/sc/202...
🎄On the 8th day of Christmas, Kazunari Domen et al. gave to us, a paper on oxygen!
“Z-scheme overall water splitting on photocatalyst sheet mediated by carbon nanotubes using oxysulfide photocatalyst responsive to long wavelengths”
Read it here: doi.org/10.1039/D5SC...
“Z-scheme overall water splitting on photocatalyst sheet mediated by carbon nanotubes using oxysulfide photocatalyst responsive to long wavelengths”
Read it here: doi.org/10.1039/D5SC...
January 1, 2026 at 1:00 PM
🎄On the 8th day of Christmas, Kazunari Domen et al. gave to us, a paper on oxygen!
“Z-scheme overall water splitting on photocatalyst sheet mediated by carbon nanotubes using oxysulfide photocatalyst responsive to long wavelengths”
Read it here: doi.org/10.1039/D5SC...
“Z-scheme overall water splitting on photocatalyst sheet mediated by carbon nanotubes using oxysulfide photocatalyst responsive to long wavelengths”
Read it here: doi.org/10.1039/D5SC...
🎄On the 7th day of Christmas, Anindita Das et al. gave to us, a paper on N!
“Crystallization-driven 2D assemblies from a phenothiazine-conjugated poly(l-lactide): redox-responsive tunable emission, white-light harvesting and surface-enabled NP decoration”
Read it here: doi.org/10.1039/D5SC...
“Crystallization-driven 2D assemblies from a phenothiazine-conjugated poly(l-lactide): redox-responsive tunable emission, white-light harvesting and surface-enabled NP decoration”
Read it here: doi.org/10.1039/D5SC...
December 31, 2025 at 1:00 PM
🎄On the 7th day of Christmas, Anindita Das et al. gave to us, a paper on N!
“Crystallization-driven 2D assemblies from a phenothiazine-conjugated poly(l-lactide): redox-responsive tunable emission, white-light harvesting and surface-enabled NP decoration”
Read it here: doi.org/10.1039/D5SC...
“Crystallization-driven 2D assemblies from a phenothiazine-conjugated poly(l-lactide): redox-responsive tunable emission, white-light harvesting and surface-enabled NP decoration”
Read it here: doi.org/10.1039/D5SC...
🎄On the 6th day of Christmas, Vivek Polshettiwar et al. gave to us, a paper on carbon!
“Synthesis of Synergistic Catalysts: Integrating Defects, SMSI, and Plasmonic Effects for Enhanced Photocatalytic CO2 Reduction”
Read it here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
“Synthesis of Synergistic Catalysts: Integrating Defects, SMSI, and Plasmonic Effects for Enhanced Photocatalytic CO2 Reduction”
Read it here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
December 30, 2025 at 1:00 PM
🎄On the 6th day of Christmas, Vivek Polshettiwar et al. gave to us, a paper on carbon!
“Synthesis of Synergistic Catalysts: Integrating Defects, SMSI, and Plasmonic Effects for Enhanced Photocatalytic CO2 Reduction”
Read it here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
“Synthesis of Synergistic Catalysts: Integrating Defects, SMSI, and Plasmonic Effects for Enhanced Photocatalytic CO2 Reduction”
Read it here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
🎄On the 5th day of Christmas, R. Graham Cooks et al. gave to us, a paper on boron!
“Accelerated Click Reactions using Boronic Acids for Heterocyclic Synthesis in Microdroplets”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
“Accelerated Click Reactions using Boronic Acids for Heterocyclic Synthesis in Microdroplets”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
December 29, 2025 at 1:00 PM
🎄On the 5th day of Christmas, R. Graham Cooks et al. gave to us, a paper on boron!
“Accelerated Click Reactions using Boronic Acids for Heterocyclic Synthesis in Microdroplets”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
“Accelerated Click Reactions using Boronic Acids for Heterocyclic Synthesis in Microdroplets”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
🎄On the 4th day of Christmas, Andrès Reyes et al. gave to us, a paper on beryllium!
“Watch out electrons!: Positron Binding Redefines Chemical Bonding in Be2”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
“Watch out electrons!: Positron Binding Redefines Chemical Bonding in Be2”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
December 28, 2025 at 1:00 PM
🎄On the 4th day of Christmas, Andrès Reyes et al. gave to us, a paper on beryllium!
“Watch out electrons!: Positron Binding Redefines Chemical Bonding in Be2”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...
“Watch out electrons!: Positron Binding Redefines Chemical Bonding in Be2”
Read it for free here: doi.org/10.1039/D5SC...
Featured in: rsc.li/chemsci-commu...