#cancerimmunotherapy
This review highlights how endo/exonucleases regulate #DNADamage repair, #genome stability, and #cGASSTING signaling, with controlled activity preventing #autoimmunity while excessive cleavage enhances #CancerImmunotherapy. #AutoimmuneDiseases

#OpenAccess: doi.org/10.1016/j.ge...
December 26, 2025 at 4:34 PM
IL-27 emerges as a powerful amplifier of cytotoxic T cell activity, offering a blueprint for next-gen cancer immunotherapies.
#IL27 #CTLs #CancerImmunotherapy #TCellActivation #Immunoregulation
www.nature.com/articles/s41...
December 9, 2025 at 4:19 PM
#Medsky🧪 #IDSky #immunosky #Oncosky #publichealth The study explores the long-term implications of #COVID19pandemic on #cancerimmunotherapy.
🔑
-Persistent 🦠 spike protein exposure can sustain inflammatory pathways, disrupting the tumor microenvironment & compromising #immunotherapy efficacy.
Post COVID-19 pandemic Inflammatory Insights into Cancer: Consequences for immunotherapy
The COVID-19 pandemic has reshaped the landscape of global health, revealing novel interactions between infectious diseases and chronic conditions suc…
www.sciencedirect.com
December 7, 2025 at 7:48 AM
A #court in Munich has granted a preliminary #injunction that will prevent #MSD from distributing the #subcutaneous version of its #cancerimmunotherapy Keytruda in the #Germanmarket.

pharmaphorum.com/news/setback...
Setback for MSD as German court blocks Keytruda SC launch
A court in Germany has granted an injunction that will prevent MSD from distributing the new, subcutaneous version of its cancer drug Keytruda.
pharmaphorum.com
December 5, 2025 at 11:20 AM
🔬 PhD THESIS DEFENCE

🔹Student: Noelia Hernández from the Nanomedicine Lab
🔹Directors: ICREA Prof. Kostas Kostarelos & Dr Neus Lozano

📆 11/12/2025
⏰ 3:30 PM
📍 ICN2 Seminar Room
📝 Register at 👉 https://f.mtr.cool/cdmbbfcdcn

🍀 Good luck, Noelia!

#CancerImmunotherapy #PhDthesis
December 5, 2025 at 9:45 AM
#Highlight in #MedComm
PPP2R1A Mutation: A Critical Amplifier for Immune Checkpoint Blockade Therapy Efficacy doi.org/10.1002/mco2...

The highlighted article in @nature.com : doi.org/10.1038/s415...

#CancerImmunotherapy #OvarianCancer #Tumour #biomarker
December 5, 2025 at 8:10 AM
#Neutrophil-targeted #STAT3 inhibition reshapes #neutrophils into #antitumor effectors, suppresses tumor growth, and boosts cytotoxic CD8⁺ T-cell activity, highlighting STAT3 blockade as a promising #CancerImmunotherapy strategy. @unidue.bsky.social

#STTT: doi.org/10.1038/s413...
December 4, 2025 at 9:12 AM
Lunai Bioworks has secured a licensing LOI for our DCCT platform after seeing complete regression of pancreatic tumors in humanized models. #cancerimmunotherapy #pancreaticcancer #celltherapy
November 25, 2025 at 7:50 PM
First-in-human phase 1b/2 trial shows allogeneic NK cell therapy with gemcitabine and S-1 is safe and effective in advanced #PancreaticCancer, identifying NK and T-cell subsets that affect outcomes. #CancerImmunotherapy #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...
Dynamic transcriptional immune landscape in response to NK-cell therapy combined with gemcitabine plus S-1 in advanced pancreatic cancer: a phase 1b/2 trial - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Dynamic transcriptional immune landscape in response to NK-cell therapy combined with gemcitabine plus S-1 in advanced pancreatic cancer: a phase 1b/2 trial
doi.org
November 25, 2025 at 12:30 PM
If you’re at #SITC2025 this week, stop by the AAI Booth 639! Learn about our #Immunology journals (The Journal of Immunology and ImmunoHorizons), our annual meeting #IMMUNOLOGY2026, and AAI membership. We can't wait to connect in person! #CancerImmunotherapy
November 6, 2025 at 9:30 PM
🩺 HOW THIS STUDY MIGHT AFFECT RESEARCH,
PRACTICE OR POLICY
Systemic effects of long-term UVR exposure lead to systemic #immunosuppression, which impacts #melanoma & non-melanoma #CancerImmunotherapy

These findings suggest that patients may benefit
from avoiding ☀️sun exposure during #Immunotherapy
Systemic immunosuppression from ultraviolet radiation exposure inhibits cancer immunotherapy
Background Ultraviolet radiation (UVR) affects local cutaneous and systemic immunity acutely. The wavelength, pattern and intensity of UVR exposure, individual skin phototype and immune state of indiv...
jitc.bmj.com
November 3, 2025 at 10:14 AM
October 15, 2025 at 4:24 AM
Unlocking Immune Secrets: The medicine nobel prize 2025 Revolution
The scientific community has been galvanized by the announcement of the medicine nobel prize 2025, honoring three scientists whose work fundamentally redefined our understanding of the human immune system. Mary E. Brunkow, Fred Ramsdell (both USA), and Shimon Sakaguchi (Japan) were jointly awarded the prestigious prize for their “discoveries concerning peripheral immune tolerance.” ​This groundbreaking research unveiled the crucial mechanisms that prevent our powerful immune defenses from mistakenly attacking the body’s own tissues—a condition known as autoimmunity. Their collective work identified the immune system’s ultimate “security guards”: Regulatory T-cells (Tregs), establishing a new pillar in the field of modern immunology. […]
www.jeedailynews.online
October 8, 2025 at 2:47 PM
Preserving lymph nodes during cancer surgery may boost checkpoint blockade and CAR‑T therapy effectiveness, according to two Nature Immunology papers (15 Sep 2025, 29 Jul 2025). https://getnews.me/preserving-lymph-nodes-may-boost-cancer-immunotherapy-outcomes/ #cancerimmunotherapy #lymphnodes
September 30, 2025 at 10:27 AM
Biomimetic polypeptide nano-immunomodulator tunes macrophage polarization, boosting antitumor immunity with high biocompatibility. #CancerImmunotherapy #Nanomedicine
Details: doi.org/10.34133/bdr.0006
September 27, 2025 at 2:56 AM
Last week, our team had the privilege of attending CICON 2025 in Utrecht!
We’re putting together a digest of highlights from selected talks dropping on September 24.
Stay tuned for key takeaways you won’t want to miss.
#CICON25 #CancerImmunotherapy
September 20, 2025 at 1:05 PM
'Armored and Cold Tumors: A Refractory Subset of Solid Cancer' - a new #BIOIntegration published commentary on #ScienceOpen 📄🔓🖇️ #ArmoredAndColdTumors #TumorMicroenvironment #CancerImmunotherapy #OncologyResearch
Armored and Cold Tumors: A Refractory Subset of Solid Cancer
Solid tumors are characterized by extensive extracellular matrix (ECM) remodeling prominently featuring massive collagen deposition.
www.scienceopen.com
September 18, 2025 at 3:18 PM
Breaking News in Cancer Immunotherapy!​​

Highlights from ​​FIT Cancer 11​​ (Madrid, 2025) — Spain’s premier #ImmunoOncology meeting organized by GETICA_Spain
www.mdpi.com/2673-9992/36...

Dive into the abstracts shaping the future of #CancerImmunotherapy

#CellTherapy #Biomarkers
September 15, 2025 at 2:46 PM