#PenicillinAllergy
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trubianojason.bsky.social
The largest adult #penicillinallergy study ever undertaken - The iNAAN study @thedohertyinst.bsky.social @unimelb.bsky.social - 52 hospitals, 8 countries and over 5000 patients….Real world proof of the safety and effectiveness of inpatient DOC! Stay tuned #AMS folks 👀Results soon!
November 21, 2025 at 11:50 PM
trubianojason.bsky.social
Is one dose ever enough? The PROSPECTOR 🪓 Trial will answer - A international double blind placebo controlled trial of 1 dose vs 5 day for #penicillinallergy. This week we recruited our 100th patient! 🎉 @thedohertyinst.bsky.social
November 21, 2025 at 11:04 AM
aaaaiorg.bsky.social
Members of the AAAAI Board of Directors met with key Capitol Hill offices today to advocate on issues critical to members and patients. These discussions are vital to strengthening the specialty and improving patient care.

https://www.aaaai.org/about/advocacy/sustainability

#PenicillinAllergy
November 20, 2025 at 10:26 PM
trubianojason.bsky.social
My Top 5 Antibiotic Allergy Papers - #5
▶️Gadde et al. JAMA 1993; 270 (20)
▶️ A paper before its time. Skin testing for #penicillinallergy in patients with ID indication!
▶️ 7.1% + ; PPL & MDM utilisation; safety (1/128+ required adrenaline); Allergy LOSS WITH TIME.
jamanetwork.com/journals/jam...
Clinical Experience With Penicillin Skin Testing in a Large Inner-City STD Clinic
Objective.  —To establish (1) the prevalence of positive penicillin skin tests among outpatients with well-defined but variable history of penicillin allergy and (2) the reproducibility, safety, a...
jamanetwork.com
November 12, 2024 at 3:52 AM
pharmaj.bsky.social
Almost 90% of people whose medical records labelled them as allergic to penicillin were not truly allergic, a study funded by the National Institute for Health and Care Research has suggested
#ukpharmacy #penicillinallergy
Almost nine in ten patients labelled allergic to penicillin had no allergy, study finds
Almost 90% of people whose medical records labelled them as allergic to penicillin were not truly allergic, a study funded by the National Institute for Health and Care Research has suggested.…
buff.ly
July 16, 2025 at 1:56 PM
trubianojason.bsky.social
Thought worth a share on #WAAW @ncas.bsky.social day today. A practical guide to #penicillinallergy into inpatient #AMS programs. A partner to implementation! #IDSky #MedSky
pubmed.ncbi.nlm.nih.gov/39444148/
Adult penicillin allergy programmes in Australian hospitals: a practical guide from the National Antibiotic Allergy Network - PubMed
Penicillin allergy is a significant burden on patient, prescribing and hospital outcomes. There has been increasing interest in the incorporation of penicillin allergy testing (i.e. delabelling) into ...
pubmed.ncbi.nlm.nih.gov
November 22, 2024 at 12:04 AM
drknowledgeplus.bsky.social
PenicillinG
#Post20

#PenicillinG #Antibiotics #BacterialInfections #SyphilisTreatment #RheumaticFeverPrevention #InjectionTherapy #HowItWorks #AntibioticMechanism #DrugSideEffects #AllergicReactions #PenicillinAllergy #MedicationGuide #CompleteTheCourse #AntibioticResistance #SafeMedicationUse
PenicillinG #Post20 ☆ Uses ● Penicillin G is used to treat bacterial infections. ● It is effective in treating syphilis. ● It is also used for the prevention of rheumatic fever. ● Additionally, it helps prevent recurrence of rheumatic fever. ● How Penicillin G Works ● Penicillin G is an antibiotic. ● It kills bacteria by preventing the formation of their protective cell wall, which is essential for their survival. ● Without this wall, bacteria are unable to live and multiply, helping clear the infection. ☆ Common Side Effects of Penicillin G ● Pain, swelling, or redness at the injection site ● Nausea or vomiting ● Diarrhea ● Rash or skin irritation ● Itching ● Headache ● Fever ● Allergic reactions (mild forms like rash or itching) ☆ Advice for Penicillin G ● You have been prescribed Penicillin G for the treatment of bacterial infections. ● It is administered by injection into a vein or muscle, or through a drip into a vein. ● Complete the full course of treatment, even if you start feeling better. ● Stopping the medicine early may cause the infection to return and become harder to treat. ● Diarrhea may occur as a side effect, but it usually stops when the course is finished. ● Inform your doctor if diarrhea persists or if you notice blood in your stools. ● Seek medical attention immediately if you experience: • Itchy rash • Swelling of the face, throat, or tongue • Breathing difficulties ☆ What important things should I tell my doctor before starting Penicillin G? ● Tell your doctor if you have ever had an allergic reaction to Penicillin G or any similar medicine. ● Inform your doctor if you have any type of allergy, including drug, food, or environmental allergies. ● Mention if you have asthma or any breathing problems. ● Let your doctor know if you have a history of heart disease. ● Inform your doctor if you have kidney disease or any kidney-related issues. ● Share a list of all medications you are currently taking, including prescription, over-the-counter, an…
June 3, 2025 at 1:17 PM
arxivlens.bsky.social
The cost-effectiveness of penicillin allergy testing: Evidence and gaps from a systematic review.
Ahmed, Shadia et al.
Paper
Details
#PenicillinAllergy #CostEffectiveness #SystematicReview
December 20, 2025 at 9:01 AM
trubianojason.bsky.social
1000 direct oral #penicillinallergy challenges in the prospective iNAAN study 🎉- 39 hospitals and 7 countries 😳. The largest adult penicillin challenge study! Well done @elisemitri.bsky.social 👏👏 and all collaborators! @escmid.bsky.social data coming hopefully to #ESCMIDglobal 2025!
November 23, 2024 at 4:25 AM
jamanetworkopen.com
Discrepancies between allergist assessments and #EHR documentation of #PenicillinAllergy persist, with nearly half of cases in a recent study showing disagreement, especially in risk classification. ja.ma/48YLuRC
JAMA Network Open article: "Disagreement Between Allergist and Electronic Health Record Documentation of Penicillin Allergies" by Theresa B. Dunham and Kimberly G. Blumenthal, published online December 19, 2025.
December 20, 2025 at 5:30 PM
trubianojason.bsky.social
We randomised our first patients yesterday into the #PROSPECTOR2 ⛏️ study - international superioty trail of 1 dose versus day challenge for #penicillinallergy. “Is one dose ever enough….”
March 26, 2025 at 8:50 PM
cea01.bsky.social
PEN-FAST rule validated for penicillin allergy in Asia—supports safe antibiotic use and better patient care. #PenicillinAllergy #ClinicalTools

doi.org/10.1111/cea....
Validation of the PEN‐FAST Penicillin Allergy Clinical Decision Rule in an Asian Cohort
PEN-FAST ≤ 2 shows high NPV, validating it as a reliable screening tool in Asians. Direct drug provocation is safe for low-risk patients identified by PEN-FAST ≤ 2. PEN-FAST shows modest discriminati...
doi.org
November 5, 2025 at 12:22 PM
trubianojason.bsky.social
Is one dose enough?! Great talk from Dr Rose for the #PROSPECTOR #penicillinallergy #RCT at #EAACI HK Summer School. 6.7% increase in immune mediated reactions with prolonged oral challenge. Looking forward to #PROSPECTOR2 definitive phase III study to change practice!
August 28, 2025 at 1:54 PM
aaaaiorg.bsky.social
Drug allergy expert David Khan, MD, FAAAAI, discusses the importance of evaluating patients with reported penicillin allergy and how allergists can partner with other healthcare providers to make sure all the patients with this label are evaluated. www.aaaai.org/professional...

#PenicillinAllergy
September 23, 2025 at 7:23 PM
trubianojason.bsky.social
#PROSPECTOR1 ⛏️double blind pilot feasibility RCT of single dose vs. multi dose challenge for #penicillinallergy fully recruited! Can’t wait for the results… and PROSPECTOR2 to commence internationally in 2025! Stay tuned… #IDSky #MedSky #AISky
November 15, 2024 at 10:18 PM
trubianojason.bsky.social
My Top 5 Antibiotic Allergy Papers.... #IDSky #MedSky #Penicillinallergy #Antibioticallergy.
trubianojason.bsky.social Jason Trubiano @trubianojason.bsky.social · Nov 12
My Top 5 Antibiotic Allergy Papers - #5
▶️Gadde et al. JAMA 1993; 270 (20)
▶️ A paper before its time. Skin testing for #penicillinallergy in patients with ID indication!
▶️ 7.1% + ; PPL & MDM utilisation; safety (1/128+ required adrenaline); Allergy LOSS WITH TIME.
jamanetwork.com/journals/jam...
Clinical Experience With Penicillin Skin Testing in a Large Inner-City STD Clinic
Objective.  —To establish (1) the prevalence of positive penicillin skin tests among outpatients with well-defined but variable history of penicillin allergy and (2) the reproducibility, safety, a...
jamanetwork.com
November 12, 2024 at 8:01 AM
trubianojason.bsky.social
Excited to be at EAACI Hong Kong School 2025 Hosted by Prof Li. Can’t wait for Elise Mitri from The Peter Doherty Institute to present the #iNAAN Results - #PenicillinAllergy #delabing Global Implementation! Dr Rose will present #PROSPECTOR1 - is one dose enough to delabel penicillin allergy?!? ‼️👀
August 27, 2025 at 2:02 AM
stephenhughes.bsky.social
Our local Prescribing in Penicillin Allergy guide has been updated after much work.
This will help us safely identify those who can tolerate penicillin, ensuring they receive the best possible treatment. #PenicillinAllergy #AntibioticStewardship #PatientSafety
February 19, 2025 at 10:46 PM
trubianojason.bsky.social
Congratulations Elise Mitri from NACE, Austin Health & The Peter Doherty Institute presenting the iNAAN Trial results - > 5000 pts & 1500 inpatient #penicillinallergy DOC performed. Safe irrespective of stakeholder with significant prescribing gains. Largest inpatient penicillin allergy study 👏🎉
August 29, 2025 at 8:17 AM
auscandoc.bsky.social
www.cbc.ca/news/canada/...

“..tool for health-care professionals to assess and identify if patients who think they have a #penicillinallergy… about 10 per cent of people report having an allergy to penicillin — but fewer than one per cent actually have a true allergy. “
B.C. allergist working to combat false penicillin allergy diagnoses | CBC News
Dr. Tiffany Wong, co-lead of a penicillin de-labelling project, has developed a tool for health-care professionals to assess and identify if patients who think they have a penicillin allergy are actually at low risk of having one.
www.cbc.ca
November 10, 2025 at 8:18 PM
purescience.news
Up to 1 in 5 Americans Think They're Allergic to Penicillin. Most Aren't. #Science #HealthandMedicine #InfectiousDiseases #PenicillinAllergy #HealthAwareness #MedicalMyths
Up to 1 in 5 Americans Think They're Allergic to Penicillin. Most Aren't.
A pharmacist explains.
purescience.news
August 4, 2025 at 3:32 AM
auscandoc.med-mastodon.com.ap.brid.gy
https://www.cbc.ca/news/canada/british-columbia/penicilin-diagnoses-fake-bc-9.6971679

“..tool for health-care professionals to assess and identify if patients who think they have a #penicillinallergy… about 10 per cent of people report having an allergy to penicillin — but fewer than one per […]
Original post on med-mastodon.com
med-mastodon.com
November 10, 2025 at 8:20 PM
aaaaiorg.bsky.social
Approximately 10% of patients report an allergy to penicillin. However, the majority of patients (greater than 90%) may not truly be allergic. Most people lose their penicillin allergy over time, even those with a history of anaphylaxis. #NWHW #PenicillinAllergy
www.youtube.com/watch?v=TZWc...
May 13, 2025 at 7:37 PM