Is IgG4 related disease really that rare? Don't think so...
December 16, 2025 at 6:43 PM
Is IgG4 related disease really that rare? Don't think so...
Our Jan 2026 issue is live!
Including #RheumatoidArthritis, #IgG4-related disease, and #SystemicSclerosis, plus much more! thelancet.com/journals/lan...
#Medsky #Rheumsky
And introducing our cover artist for 2026, Emma Cheng @emma-cheng.bsky.social
Including #RheumatoidArthritis, #IgG4-related disease, and #SystemicSclerosis, plus much more! thelancet.com/journals/lan...
#Medsky #Rheumsky
And introducing our cover artist for 2026, Emma Cheng @emma-cheng.bsky.social
December 16, 2025 at 10:02 AM
Our Jan 2026 issue is live!
Including #RheumatoidArthritis, #IgG4-related disease, and #SystemicSclerosis, plus much more! thelancet.com/journals/lan...
#Medsky #Rheumsky
And introducing our cover artist for 2026, Emma Cheng @emma-cheng.bsky.social
Including #RheumatoidArthritis, #IgG4-related disease, and #SystemicSclerosis, plus much more! thelancet.com/journals/lan...
#Medsky #Rheumsky
And introducing our cover artist for 2026, Emma Cheng @emma-cheng.bsky.social
IgG4-related Disease Market Insights Highlight Expanding Outlook Till 2034, DelveInsight Evaluates | Zenas BioPharma, Horizon Therapeutics, Amgen, Sanofi, UMC Utrecht
->The Globe and Mail | #disease #health | More from Lil Dr Glen EcoChat at BigEarthData.ai
->The Globe and Mail | #disease #health | More from Lil Dr Glen EcoChat at BigEarthData.ai
IgG4-related Disease Market Insights Highlight Expanding Outlook Till 2034, DelveInsight Evaluates | Zenas BioPharma, Horizon Therapeutics, Amgen, Sanofi, UMC Utrecht
The Key IgG4-related Disease Companies in the market include - Zenas BioPharma, Horizon Therapeutics, Amgen, Sanofi, UMC Utrecht, and others. DelveInsight’s “IgG4-related Disease Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the IgG4-related Disease, historical and...
www.theglobeandmail.com
December 12, 2025 at 5:55 PM
This is not immunobridging. The meaning of the IgG4 class switching is unclear and there are compelling arguments for why it could be a net positive. It is clear both the mRNA vaccines and Novavax's are protective.
December 8, 2025 at 8:07 PM
This is not immunobridging. The meaning of the IgG4 class switching is unclear and there are compelling arguments for why it could be a net positive. It is clear both the mRNA vaccines and Novavax's are protective.
I contend they are using the methodology chosen by the mRNA companies to represent themselves in VRBPAC and ACIP. And it’s not the only data they use or present. Since Novavax doesn’t induce IgG4 switch and induces a different immune response from mRNA; appears comparable but not the whole story
December 8, 2025 at 8:04 PM
I contend they are using the methodology chosen by the mRNA companies to represent themselves in VRBPAC and ACIP. And it’s not the only data they use or present. Since Novavax doesn’t induce IgG4 switch and induces a different immune response from mRNA; appears comparable but not the whole story
Widespread Fab-arm exchange occurs in serum of healthy donors and leads to a massive explosion in the molecular diversity of the IgG4 clonal repertoire
@natcomms.nature.com @uuuips.bsky.social
www.nature.com/articles/s41...
image from 10.3389/fimmu.2024.1272084
@natcomms.nature.com @uuuips.bsky.social
www.nature.com/articles/s41...
image from 10.3389/fimmu.2024.1272084
December 8, 2025 at 4:55 PM
Widespread Fab-arm exchange occurs in serum of healthy donors and leads to a massive explosion in the molecular diversity of the IgG4 clonal repertoire
@natcomms.nature.com @uuuips.bsky.social
www.nature.com/articles/s41...
image from 10.3389/fimmu.2024.1272084
@natcomms.nature.com @uuuips.bsky.social
www.nature.com/articles/s41...
image from 10.3389/fimmu.2024.1272084
The CXCL12‐CXCR4 Axis Mediates Lymphocyte Immune Overactivation in IgG4‐Related Chronic #Rhinosinusitis. First author: Jing Ding; corresponding authors: Luo Zhang, Yingshi Piao. Read the article here: doi.org/10.1111/all.70124
December 8, 2025 at 4:36 PM
The CXCL12‐CXCR4 Axis Mediates Lymphocyte Immune Overactivation in IgG4‐Related Chronic #Rhinosinusitis. First author: Jing Ding; corresponding authors: Luo Zhang, Yingshi Piao. Read the article here: doi.org/10.1111/all.70124
Widespread Fab-arm exchange affects all endogenous serum IgG4 #nature #MassSpecRSS
Widespread Fab-arm exchange affects all endogenous serum IgG4 - Nature Communications
Among the antibody subclasses, IgG4 is unique in its capability to fragment-antigen-binding (Fab)-arm exchange, a process that renders IgG4 bispecific for antigen binding. Here authors analyse serum IgG4 clonal repertoires of healthy human donors to show that Fab-arm exchange is widespread and affects all IgG4 clones.
dlvr.it
December 8, 2025 at 7:01 AM
Widespread Fab-arm exchange affects all endogenous serum IgG4 #nature #MassSpecRSS
Dr. Ying Wang presents updated Ph1b/2 study data w/ MK-1045 (humanized bispecific IgG4 CD19xCD3 T-cell engager) in R/R B-ALL. Long-half life allows weekly IV admin (not IVCI). 75 pts treated, 10 dose levels; 73 efficacy-evaluable. CR/CRi/CRh in 55% (83% w/ dose ≥60mg). 9 w/ (1/2) #ASH25 prior blina
December 7, 2025 at 10:34 PM
Dr. Ying Wang presents updated Ph1b/2 study data w/ MK-1045 (humanized bispecific IgG4 CD19xCD3 T-cell engager) in R/R B-ALL. Long-half life allows weekly IV admin (not IVCI). 75 pts treated, 10 dose levels; 73 efficacy-evaluable. CR/CRi/CRh in 55% (83% w/ dose ≥60mg). 9 w/ (1/2) #ASH25 prior blina
Chinese researchers have identified overlapping but distinct clinicopathologic features of immunoglobulin 4-related ophthalmic disease (#IgG4ROD), a form of IgG4-related disease (#IgG4RD), and #CastlemanDisease (CD). Report in the Indian Journal of Ophthalmology
Read more: https://bit.ly/48NGDDX
Read more: https://bit.ly/48NGDDX
Differences Observed in Clinical Features of IgG4-ROD and Castleman Disease
Both IgG4-ROD and Castleman disease may present as orbital masses or lacrimal gland enlargement, but they differ in imaging and histologic markers.
bit.ly
December 4, 2025 at 5:50 PM
Chinese researchers have identified overlapping but distinct clinicopathologic features of immunoglobulin 4-related ophthalmic disease (#IgG4ROD), a form of IgG4-related disease (#IgG4RD), and #CastlemanDisease (CD). Report in the Indian Journal of Ophthalmology
Read more: https://bit.ly/48NGDDX
Read more: https://bit.ly/48NGDDX
This Saturday at the W Los Angeles - West Beverly Hills: "Rheum Forum: Advances in Immunotherapy for IgG4-RD, ANCA-Associated Vasculitis, and Beyond."
Register today to save your seat: events.vindicocme.com/en/15kYU86/g...
#Rheumatology #CME #AAPA
Register today to save your seat: events.vindicocme.com/en/15kYU86/g...
#Rheumatology #CME #AAPA
December 1, 2025 at 2:38 PM
This Saturday at the W Los Angeles - West Beverly Hills: "Rheum Forum: Advances in Immunotherapy for IgG4-RD, ANCA-Associated Vasculitis, and Beyond."
Register today to save your seat: events.vindicocme.com/en/15kYU86/g...
#Rheumatology #CME #AAPA
Register today to save your seat: events.vindicocme.com/en/15kYU86/g...
#Rheumatology #CME #AAPA
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
November 29, 2025 at 8:21 AM
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
November 29, 2025 at 2:46 AM
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
November 29, 2025 at 2:44 AM
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
November 29, 2025 at 1:45 AM
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
November 29, 2025 at 1:15 AM
Global Indication Lead, Rilzabrutnib IgG4, Rheumatology TA, Immunology Franchise - Cambridge Job educativ.net/jobs/job/49297...
Immunoglobulin G4-related disease (#IgG4RD) is associated with distinct allergen-specific IgE and IgG4 signatures, with certain environmental antigens linked to organ-specific involvement. Study in @allergy-eaaci.bsky.social
Read here: https://bit.ly/43SpXbH
#RareDisease #MedSky
Read here: https://bit.ly/43SpXbH
#RareDisease #MedSky
Distinct Allergen-Specific IgE, IgG4 Signatures Define Organ Involvement in IgG4-RD
New research showed that IgG4-RD features distinct allergen-specific IgE and IgG4 signatures, with some environmental antigens tied to organ involvement.
bit.ly
November 25, 2025 at 6:53 PM
Immunoglobulin G4-related disease (#IgG4RD) is associated with distinct allergen-specific IgE and IgG4 signatures, with certain environmental antigens linked to organ-specific involvement. Study in @allergy-eaaci.bsky.social
Read here: https://bit.ly/43SpXbH
#RareDisease #MedSky
Read here: https://bit.ly/43SpXbH
#RareDisease #MedSky
Mahsa Pazokifard shares her powerful story of spending years searching for answers before finally being diagnosed with IgG4-Related Disease — and how self-advocacy became her lifeline.
Listen to the full episode: ghlf.org/the-health-a...
#RareDisease #IgG4RD #PatientAdvocacy
Listen to the full episode: ghlf.org/the-health-a...
#RareDisease #IgG4RD #PatientAdvocacy
November 23, 2025 at 9:49 PM
Mahsa Pazokifard shares her powerful story of spending years searching for answers before finally being diagnosed with IgG4-Related Disease — and how self-advocacy became her lifeline.
Listen to the full episode: ghlf.org/the-health-a...
#RareDisease #IgG4RD #PatientAdvocacy
Listen to the full episode: ghlf.org/the-health-a...
#RareDisease #IgG4RD #PatientAdvocacy
Do you know if the IgG4 class switching has been studied in sa-mRNA vaccines?
November 14, 2025 at 9:27 PM
Do you know if the IgG4 class switching has been studied in sa-mRNA vaccines?
Earn #CME or #AAPA credits at the Rheum Forum in Los Angeles! Register today to learn about advances in immunotherapy for IgG4-RD and AAV: events.vindicocme.com/en/15kYU86/g...
#Rheumatology
#Rheumatology
November 14, 2025 at 8:42 PM
Earn #CME or #AAPA credits at the Rheum Forum in Los Angeles! Register today to learn about advances in immunotherapy for IgG4-RD and AAV: events.vindicocme.com/en/15kYU86/g...
#Rheumatology
#Rheumatology
IGG4-Related Disease Market Size, Growth Drivers and Global www.openpr.com/news/4179484...
IGG4-Related Disease Market Size, Growth Drivers and Global Forecast 2034 | At a Thriving CAGR of 7.78%
Introduction Rising Focus on Autoimmune Disorders The IGG4 Related Disease market is witnessing remarkable momentum as research continues to uncover new therapeutic options and diagnostic advancements...
www.openpr.com
November 14, 2025 at 5:33 AM
IGG4-Related Disease Market Size, Growth Drivers and Global www.openpr.com/news/4179484...
IGG4-Related Disease Market Projected to Hit USD 6.08 Billion by 2035, at a Exceptional CAGR 7.78% - Industry Today industrytoday.co.uk/health_and_s...
IGG4-Related Disease Market Projected to Hit USD 6.08 Billion by 2035, at a Exceptional CAGR 7.78% - Industry Today
IGG4-Related Disease market is projected to experience substantial growth from 2.67 USD billion in 2024 to 6.08 USD billion by 2035.
industrytoday.co.uk
November 14, 2025 at 5:29 AM
IGG4-Related Disease Market Projected to Hit USD 6.08 Billion by 2035, at a Exceptional CAGR 7.78% - Industry Today industrytoday.co.uk/health_and_s...
Our next science bite from Carissa Aurelia @carissaaurelia.bsky.social from @thedohertyinst.bsky.social
presenting on the bispecific role of IgG4 antibodies to SARS-CoV-2
#YoungVIIN2025 #VIINYIS
presenting on the bispecific role of IgG4 antibodies to SARS-CoV-2
#YoungVIIN2025 #VIINYIS
November 14, 2025 at 5:22 AM
Our next science bite from Carissa Aurelia @carissaaurelia.bsky.social from @thedohertyinst.bsky.social
presenting on the bispecific role of IgG4 antibodies to SARS-CoV-2
#YoungVIIN2025 #VIINYIS
presenting on the bispecific role of IgG4 antibodies to SARS-CoV-2
#YoungVIIN2025 #VIINYIS