#Cells_MDPI
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haoyin.bsky.social
Meningeal vascular remodeling in 2~4 mo ovariectomized🐭
⏬blood vessel length
⏫blood vessel tortuosity
⏫PDPL+ lymphatic vessel area fraction
Ectopic vessel muscularization
Perivascular scattered αSMA+ cells in dura mater

#Cells_MDPI 2025
www.mdpi.com/2073-4409/14...
November 15, 2025 at 11:20 PM
haoyin.bsky.social
#Pericyte #Retina

Pericyte Vegfa KO🐭
👉⏬Vascular radial outgrowth, sprouting tip cells P5
down P5
👉↔️Arterial patterning, fundus integrity, vascular permeability, OIR vessel obliteration/neovascularization, laser-induced CNV
👉Pericyte# ⬇️3 wk ⬆️6 mo

#Cells_MDPI 2025
www.mdpi.com/2073-4409/14...
September 28, 2025 at 6:58 PM
cellclub.bsky.social
Structure of the Secretory Compartments in Goblet Cells in the Colon and Small Intestine www.mdpi.com/3429668 #mdpicells via @Cells_MDPI
www.mdpi.com
August 15, 2025 at 3:03 PM
haoyin.bsky.social
Serial block-face SEM of mouse Heart Capillaries #EndothelialCell #Pericyte #Telocyte

There are direct physical contacts b/w CD34+/CD44+ perivascular mesenchymal cells & abluminal protrusions of EC!

#Cells_MDPI 2025
www.mdpi.com/2073-4409/14...
August 5, 2025 at 11:17 AM
drtanakabluesky.bsky.social
🤔Can we reengineer a #Neuroprotective molecule to treat #Schizophrenia without stumbling?
🧠 #KYNA causes #Ataxia fast—SZR-73?
💥Clean motor profile, delayed action—real #Promise! @MDPIOpenAccess @Cells_MDPI #NeuroTwitter #DrugDiscovery #TranslationalResearch
💊Read + RT🔁 www.mdpi.com/2073-4409/14...
July 14, 2025 at 5:51 AM
drtanakabluesky.bsky.social
#KYNA helps the brain but causes #Ataxia 😵‍💫We made SZR-73: keeps the #Neuroprotection, ditches the #Motor side effects🧠🦾First real shot at safer drugs for #SCZ & #PD!🔥 @MDPIOpenAccess @Cells_MDPI #NeuroScience #Parkinsons #Schizophrenia #DrugDiscovery #KYNA 🧬🧪⚡🤯💥👉 www.mdpi.com/2073-4409/14...
July 2, 2025 at 5:38 AM
drjimenezmoreno.bsky.social
Check out the new Special Issue from @Cells_MDPI: Autophagy in Neurological Disorders. Submit your manuscript before the 20th of October :) #autophagy
www.mdpi.com/journal/cell...
May 1, 2025 at 9:26 AM
greenwoodjohn.bsky.social
LRG1 Alters Pericyte Phenotype and Compromises Vascular Maturation www.mdpi.com/3268630 #mdpicells via @Cells_MDPI
Latest offering from the Greenwood/Moss lab. Fantastic work by Alex Hoeh showing the presence of LRG1 disturbs vessel growth. #LRG1 @UCLeye @MoorfieldsBRC #retina
www.mdpi.com
April 14, 2025 at 11:12 AM
uchicagocancer.bsky.social
Researchers from the University of Chicago published a new study in #Cells_MDPI demonstrating an association between arsenic exposure and small deletions in genes linked to non-melanoma skin cancer.
#UChicagoPHS #Uchicago_IPPH
www.mdpi.com/2073-4409/14...
Gene–Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy
Arsenic (As) is a risk factor for non-melanoma skin cancer (NMSC). From a six-year follow-up study on 7000 adults exposed to As, we reported the associations of single-nucleotide variation in tumor ti...
www.mdpi.com
January 27, 2025 at 7:15 PM
bikakenofficial.bsky.social
【論文発表】
沼津支所 主席研究員 大石智一博士 らの論文が発表されました。

A Cancer-Specific Anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerts Antitumor Activities in Human Tumor Xenograft Models mdpi.com/3030124 #mdpicells
@Cells_MDPI より

#微化研 #微生物化学研究所 #bikaken #IMC #MCRF
A Cancer-Specific Anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerts Antitumor Activities in Human Tumor Xenograft Models
Podoplanin (PDPN) overexpression is associated with poor clinical outcomes in various tumors. PDPN is involved in malignant tumor progression by promoting invasiveness and metastasis. Therefore, PDPN ...
mdpi.com
November 7, 2024 at 4:21 AM
haoyin.bsky.social
#TunnelingNanoTube mediates Pericyte-to-Endothelial Cell Mitochondrial transfer

Retinal Pericyte TNT⏫in diabetic 10-mo Ins2Akita🐭

An impressive LC-MS/MS metabolomics showing how Pericyte coculture rescues TCA cycle defects in Mitochondria-depleted EC

#Cells_MDPI 2024
www.mdpi.com/2073-4409/13...
September 22, 2024 at 6:46 PM
haoyin.bsky.social
#SmoothMuscleCell #RNAEditing ADAR1
Adult SMC Adar1 KO🐭->
1⃣100% mortality
2⃣Arterial rupture/hemorrhage in multi-organs (Brain/Lung/GI, also Aorta?)
3⃣SMC mitochondrial dysfunction + apoptosis
4⃣Extensive elastin thinning & breaks

#Cells_MDPI 2024
www.mdpi.com/2073-4409/13...
August 10, 2024 at 11:24 PM
haoyin.bsky.social
FASN/#FattyAcidSynthase #SmoothMuscleCell - #FoamCell transition

Cholesterol->⏫FASN->⏫KLF4->
⏬ABCA1 (cholesterol efflux)
⏫SOAT1 (cholesterol esterification)

Alejandra San Martin lab #Cells_MDPI 2024
www.mdpi.com/2073-4409/13...
July 19, 2024 at 7:43 PM
haoyin.bsky.social
Direct effects of Cannabidiol (up to 6 μM) on cultured👤coronary arterial #SmoothMuscleCell

⏫PDGF-induced metabolism (WST-1), proliferation
⏬PDGF-induced migration, LPS/IL1β-induced VCAM1 (not ICAM1) (Independent of CB1/CB2/TRPV1)

#Cells_MDPI 2023
www.mdpi.com/2073-4409/12...
July 8, 2024 at 7:12 PM
haoyin.bsky.social
#FGF9 physically interacts with Integrin αvβ3

FGF9 R108E acts as dominant-negative mutant - ⏬mitogenic+migratory effects of FGF9 (20:1)

Does FGF9 modify integrin signals?
How integrin blockade affect FGF9 signals?😁

Yoshikazu Takada lab Cells_MDPI 2024
www.mdpi.com/2073-4409/13...
March 18, 2024 at 7:15 PM
haoyin.bsky.social
Interesting evidence on #Lymphatic #EndMT in #Skin of #SystemicSclerosis

Human Dermal Lymphatic Microvascular #EndothelialCell
TGFβ1 10 ng/ml 48~72 h

Dr. Mirko Manetti lab Cells_MDPI 2023
www.mdpi.com/2073-4409/12...
October 4, 2023 at 12:11 PM
thebinderlab.bsky.social
And lastly– yes, I know, I’ve been guest editing this special issue @Cells_MDPI (together with @dittmannlab). And no, I had absolutely no control (or even insight) into the handling of my own manuscript, neither did Meike! This was handled very professionally.
February 1, 2025 at 11:16 PM
thebinderlab.bsky.social
Note there will be *no* further extension of the deadline! If you have a nice story on antiviral signaling, consider submitting it to @dittmannlab and myself for consideration in our Special Issue @Cells_MDPI ⬇️
February 1, 2025 at 11:11 PM
thebinderlab.bsky.social
This article is part of our special issue on antiviral signaling @Cells_MDPI, co-hosted by @dittmannlab and myself. Know what? You can still submit your own exciting work, too!
February 1, 2025 at 11:16 PM
thebinderlab.bsky.social
Kudos to Maximilian Hirschenberger, Victoria Hunszinger and Konstantin @SparrerLab for their amazing effort putting together all these facts about the role of innate immunity in post-acute sequelae!

This article has been selected as a „Featured Article“ in @Cells_MDPI!
February 1, 2025 at 11:11 PM
thebinderlab.bsky.social
This article is part of our special issue on antiviral signaling @Cells_MDPI, co-hosted by @dittmannlab and myself. Know what? You can still submit your own exciting work, too!
February 1, 2025 at 11:11 PM
thebinderlab.bsky.social
Fantastic comprehensive review on #innateimmunity in herpesvirus infection by Christine O’Connor and Ganes Sen! Alpha (HSV), Beta (HCMV) and Gamma (KSHV) #herpesvirus|es covered!

Check it out in our special issue in @Cells_MDPI!

https://www.mdpi.com/2073-4409/10/8/2122
February 1, 2025 at 11:01 PM
thebinderlab.bsky.social
@Cells_MDPI is #PubMed and @Scopus listed at a current IF of 6.6 and fully #openaccess!

It is a partner journal of @SignalSociety! Special issue may also be interesting for @CytokineSociety, @AmerSocVirol or @GesVirologie members!
February 1, 2025 at 11:11 PM
thebinderlab.bsky.social
Working on cell-intrinsic antiviral responses? RLRs, TLRs, NLRs, #interferon, #cytokines… If you have an exciting story, consider submitting to this ⬇️ special issue of @Cells_MDPI, edited by @dittmannlab and myself!

@CytokineSociety @GesVirologie @ASVPresident @SignalSociety
thebinderlab.bsky.social The Binder Lab (DKFZ Heidelberg) @thebinderlab.bsky.social · Dec 18
Interested in cellular responses to #virus #infection, the induction, regulation and (importantly!) termination of antiviral #signaling? Then Meike @dittmannlab and myself would love to receive your manuscripts for this special issue @Cells_MDPI ⬇️
http://mdpi.com/si/70283
February 2, 2025 at 1:26 AM
thebinderlab.bsky.social
Everybody working on cell-intrinsic antiviral responses (*all* viruses, not just „the current one“)– send us your manuscripts! 😀

The first manuscripts that get recommended for publishing by all three reviewers GET 50% OFF the publishing fee!! Open Access included!
@Cells_MDPI
thebinderlab.bsky.social The Binder Lab (DKFZ Heidelberg) @thebinderlab.bsky.social · Dec 18
Interested in cellular responses to #virus #infection, the induction, regulation and (importantly!) termination of antiviral #signaling? Then Meike @dittmannlab and myself would love to receive your manuscripts for this special issue @Cells_MDPI ⬇️
http://mdpi.com/si/70283
February 2, 2025 at 1:26 AM