#COVID19vaccines
#COVID19vaccines induce antigen-specific circulating Tfh cells, as well as CD4+ T cells with Th1 polarization, which remain detectable for up to 6 months post-boost 💉 .The level of #SARSCoV2 -specific circulating Tfh cells in convalescent patients correlates with neutralizing antibody titers,
December 2, 2025 at 9:25 AM
🧨 Mucosal 💉 Strategies & Their Efficacy
-Mucosal (intranasal, oral, aerosolized) #COVID19vaccines are being developed to improve mucosal IgA responses & block infection at the entry site

www.sciencedirect.com/science/arti...

www.sciencedirect.com/science/arti...
Glycosylated Delta-receptor-binding domain mucosal vaccine elicits broadly neutralizing antibodies with protection against SARS-CoV-2 challenge
Mucosal COVID-19 vaccines are needed to block SARS-CoV-2 infection at the mucosal site. Intranasal delivery of a glycosylated Delta variant receptor-b…
www.sciencedirect.com
December 2, 2025 at 8:28 AM
The true global impact is therefore difficult to gauge, and estimates continue to evolve as more data become available …
As of now, only #COVID19vaccines & other non-pharmaceutical interventions like masks are proven effective in preventing severe #COVID and #LongCOVID.
December 1, 2025 at 6:15 AM
emphasizing the need for equitable #Covid19vaccines access & targeted interventions against the spread of immune-escape variants.

www.sciencedirect.com/science/arti...
Viral traits from deep mutational scanning and socio-demographic context predict SARS-CoV-2 lineage fitness across diverse countries
To assess the joint effects of SARS-CoV-2 viral traits (ACE2 binding, immune escape, and cell entry) and socio-demographic context on viral lineage fi…
www.sciencedirect.com
November 29, 2025 at 7:09 AM
Ive just signed & donated to this petition re #COVID19Vaccines
c.org/QGjxhrxNrV
Sign the Petition
Make COVID-19 Vaccines Universally Available in the UK - Free of Charge
c.org
November 1, 2025 at 4:54 PM
#Medsky🧪 #IDsky #immunosky #publichealth This thorough meta-analysis offers comforting proof of the #COVID19vaccines’ safety for the thyroid, with some protective benefits against Graves’ disease & mostly neutral relationships with other thyroid conditions.

journals.lww.com/annals-of-me...
October 31, 2025 at 8:29 AM
The authors emphasised the importance of preventing infections during pregnancy, especially as public trust in vaccines, including #COVID19vaccines, is eroding. By understanding the risks, parents can appropriately advocate for their children to receive proper evaluation & developmental support.
October 31, 2025 at 3:34 AM
Recap #Medsky🧪 #oncosky These studies showed that the beneficial of vaccines (esp #Covid19vaccines ) in improving the survival rate of Cancer patients with stage III/IV NSCLC & ICI initiations .
@nature.com
www.nature.com/articles/s41...
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
www.nature.com
October 30, 2025 at 5:30 AM
aiming to provide insights into future research directions & clinical management strategies.

www.tandfonline.com/doi/full/10....
Recap: 😷 & up-to-date #COVID19vaccines are most essential to prevent catching #LongCOVID or severe #COVID.
Long COVID: mechanisms of disease, multisystem sequelae, and prospects for treatment
Long COVID has emerged as a significant global health issue, affecting individuals across a wide spectrum of initial disease severity. While its definition and prevalence vary across studies, persi...
www.tandfonline.com
October 24, 2025 at 6:19 PM
Current #COVID19vaccines, remain effective at protecting against severe disease, hospitalization, and death from JN.1 & may help reduce the risk of LC
@jidjournal.bsky.social
academic.oup.com/jid/advance-...
@nature.com
www.nature.com/articles/s41...
Viral Infection and the Blood-Brain Barrier: Molecular Research Insights and Therapies
Viral infections can disrupt the blood-brain barrier via direct and indirect mechanisms and cause neurologic complications. Current treatment is limited to
academic.oup.com
October 22, 2025 at 10:32 PM
#Medsky🧪 #IDsky #immunosky #virosky #Publichealth
The IDSA guidelines suggest timing for #COVID19vaccines for immunocompromised populations.
New from IDSA, thanks to Dr William Werbel, resp virus vax in immunocompromised population:

- vax 2 weeks before or 3-6 months after immunocompromise expected
- expect blunted response if given within that window
- defer during acute rejection, illness
- adjust for viral circulation
#IDSky #IDWeek
October 20, 2025 at 7:53 PM
Ref onlinelibrary.wiley.com/toc/10969071...
#pedsky
www.frontiersin.org/journals/cel...
Studies comparing intranasal and orally aerosolized #COVID19vaccines reveal distinct IgA subtype kinetics in the respiratory tract .
Frontiers | SARS-CoV-2–specific mucosal immune response in vaccinated versus infected children
The anti-COVID-19 intramuscular vaccination induces a strong systemic but a weak mucosal immune response in adults. Little is known about the mucosal immune ...
www.frontiersin.org
October 20, 2025 at 5:21 AM
#Medsky🧪 #IDsky #Immunosky #episky #publichealth
Why are #COVID19vaccines & booster shots necessary? Based on multiple longitudinal studies involving vaccinated employees, #SARSCoV2 #antibody levels decline significantly within months of vaccination but a protective,
SARS-CoV-2-infection- and vaccine-induced antibody responses are long lasting with an initial waning phase followed by a stabilization phase
SARS-CoV-2 mRNA-based vaccine-induced immunity is thought to wane quickly based on short-term studies. Using longitudinal data, Srivastava et al. find that participants with hybrid immunity show faste...
www.cell.com
October 20, 2025 at 3:53 AM
#Medsky🧪 #oncosky #immunosky #IDsky #publichealth For patients with solid tumors, existing inflammation caused by the cancer can negatively affect their immune system's response to #COVID19vaccines.
Our paper exploring the effects of solid tumor malignancy-associated inflammation upon COVID-19 vaccine-induced antibodies is finally live!
We show that while dysregulated inflammation impairs neutralization, variant cross-reactive Fc effector functions remain robust.

www.nature.com/articles/s41...
Dysregulated inflammation in solid tumor malignancy patients shapes polyfunctional antibody responses to COVID-19 vaccination - npj Vaccines
npj Vaccines - Dysregulated inflammation in solid tumor malignancy patients shapes polyfunctional antibody responses to COVID-19 vaccination
www.nature.com
October 15, 2025 at 10:27 PM
Should we say all : N-95 m😷 , #COVID19vaccines, yearly vaccinations for children & pregnant women, biannual vaccinations for older & immunocompromised individuals
October 14, 2025 at 10:17 PM
#Medsky🧪#episky #publichealth @thelancet.com #COVID19vaccines reduced deaths by 59% overall (CAT range 17–82%), representing approximately 1·6 mil lives saved (range 1·5–1·7 mil) in those aged 25 years or older: 96% of lives saved were aged 60 years or older & 52% were aged 80 years or older;
October 13, 2025 at 7:06 AM
pmc.ncbi.nlm.nih.gov/articles/PMC...
www.researchgate.net/publication/...
While some types of #COVID19vaccines have been linked to rare blood clots, multiple large-scale studies
@bmj.com
heart.bmj.com/content/110/...
October 10, 2025 at 3:06 PM
Direct link to the quote in the article, just to complete the circle.

Oh to be a fly on the wall to see the panic, entitled ranting, and bruised egos among the "Urgency of Brunch" crowd today! 😁
October 7, 2025 at 2:28 AM
🙌🏼 #COVID19Vaccines #CovidIsNotOver #LongCovid CDC signs off,6 months & older can get an updated booster without prescription.Georgia, Louisiana,&Missouri pharmacy boards had blocked access,&nationwide many have faced coverage barriers.CVS Louisiana confirms,scripts no longer needed tomorrow!
October 6, 2025 at 10:07 PM
#Medsky🧪 #IDSky #episky #publichealth I’m feeling a bit groggy at the moment, but my mRNA vaccine is working. Here’s how mRNA #COVID19vaccines work.
From Pre dawn RFK CDC Sept 3, 2024

www.cdc.gov/covid/vaccin...
COVID-19 Vaccine Basics
Learn how COVID-19 vaccines help our bodies develop immunity to the virus that causes COVID-19.
www.cdc.gov
October 3, 2025 at 6:24 AM