Always, ALWAYS go back to the source. A thread for #AcademicSky and #MedSky 🧵.
I was surprised to see Black women excluded from a treatment that provides relief from menopausal side effects. I won't cite the paper, as my intent isn't to embarrass anyone.
1/5
I was surprised to see Black women excluded from a treatment that provides relief from menopausal side effects. I won't cite the paper, as my intent isn't to embarrass anyone.
1/5
![Screenshot of section of article text:
cervical cancer, but ET should be used with caution after adenocarcinomas. ET/HT can be used after International Federation of Obstetrics and Gynecology (FIGO) stage 1-ll estrogen-dependent endometrial cancers, [except in Black women] (last phrase underlined in red by me]
Text continues:
and can probably be used after estrogen-independent endometrial cancers. ET/HT cannot be administered or
should be used with great caution after most uterine](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:yoqbdkzhkjqz3vt4v4obfdqb/bafkreialjbwmf4yoc2tdjfwlokkldlvh35egbjzimkreopcqhi3u2zra7a@jpeg)
October 18, 2025 at 8:35 AM
Always, ALWAYS go back to the source. A thread for #AcademicSky and #MedSky 🧵.
I was surprised to see Black women excluded from a treatment that provides relief from menopausal side effects. I won't cite the paper, as my intent isn't to embarrass anyone.
1/5
I was surprised to see Black women excluded from a treatment that provides relief from menopausal side effects. I won't cite the paper, as my intent isn't to embarrass anyone.
1/5
Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework
➡️ buff.ly/1f4BUiT
#Epigenetics #GIcancers #DNAmethylation
➡️ buff.ly/1f4BUiT
#Epigenetics #GIcancers #DNAmethylation
May 6, 2025 at 10:45 AM
Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework
➡️ buff.ly/1f4BUiT
#Epigenetics #GIcancers #DNAmethylation
➡️ buff.ly/1f4BUiT
#Epigenetics #GIcancers #DNAmethylation
Un 25 % de los adenocarcinomas portan mutaciones en el gen KRAS y son considerados históricamente no tratables.
El investigador Matthias Drosten lidera un proyecto con el potencial de cambiar el paradigma terapéutico en el cáncer de pulmón con mutaciones en KRAS.
El investigador Matthias Drosten lidera un proyecto con el potencial de cambiar el paradigma terapéutico en el cáncer de pulmón con mutaciones en KRAS.
June 18, 2025 at 2:27 PM
Un 25 % de los adenocarcinomas portan mutaciones en el gen KRAS y son considerados históricamente no tratables.
El investigador Matthias Drosten lidera un proyecto con el potencial de cambiar el paradigma terapéutico en el cáncer de pulmón con mutaciones en KRAS.
El investigador Matthias Drosten lidera un proyecto con el potencial de cambiar el paradigma terapéutico en el cáncer de pulmón con mutaciones en KRAS.
In this article, the authors present a spatial multi-omics atlas of TLS-positive pancreatic ductal adenocarcinomas from patients treated with neoadjuvant immunotherapy, revealing that pathologic responses are associated with intratumoral TLS that support local maturation of IgG-secreting B cells.
November 26, 2025 at 5:05 PM
In this article, the authors present a spatial multi-omics atlas of TLS-positive pancreatic ductal adenocarcinomas from patients treated with neoadjuvant immunotherapy, revealing that pathologic responses are associated with intratumoral TLS that support local maturation of IgG-secreting B cells.
Most cases are pancreatic ductal adenocarcinomas (PDAC), which frequently develop from precursor lesions called PanINs (pancreatic intraepithelial neoplasias). Unfortunately, detecting PanINs noninvasively has been historically challenging.
January 2, 2025 at 8:35 AM
Most cases are pancreatic ductal adenocarcinomas (PDAC), which frequently develop from precursor lesions called PanINs (pancreatic intraepithelial neoplasias). Unfortunately, detecting PanINs noninvasively has been historically challenging.
like breast cancer, there is more than one type of prostate cancer, too -
Adenocarcinomas are the common type of prostate cancer- not typically an aggressive cancer
Anaplastic prostate carcinoma is an aggressive prostate cancer
Adenocarcinomas are the common type of prostate cancer- not typically an aggressive cancer
Anaplastic prostate carcinoma is an aggressive prostate cancer
May 19, 2025 at 6:44 PM
like breast cancer, there is more than one type of prostate cancer, too -
Adenocarcinomas are the common type of prostate cancer- not typically an aggressive cancer
Anaplastic prostate carcinoma is an aggressive prostate cancer
Adenocarcinomas are the common type of prostate cancer- not typically an aggressive cancer
Anaplastic prostate carcinoma is an aggressive prostate cancer
This retrospective study analyzed 568 gastric cancer cases, including 216 signet ring cell carcinomas (SRCC) and 352 adenocarcinomas (ADC), from 2020 to 2024.
October 3, 2025 at 7:47 PM
This retrospective study analyzed 568 gastric cancer cases, including 216 signet ring cell carcinomas (SRCC) and 352 adenocarcinomas (ADC), from 2020 to 2024.
Interestingly, when we analyzed published scRNA-seq datasets of other CIACs: esophageal and gastric adenocarcinomas, we found similar CAF archetypes and autocrine ligands, suggesting the ❄️cold fibrosis program as a shared, targetable circuit across CIACs
September 22, 2025 at 3:09 PM
Interestingly, when we analyzed published scRNA-seq datasets of other CIACs: esophageal and gastric adenocarcinomas, we found similar CAF archetypes and autocrine ligands, suggesting the ❄️cold fibrosis program as a shared, targetable circuit across CIACs
fuck adenocarcinomas
October 29, 2024 at 3:00 AM
fuck adenocarcinomas
🧑🏻🔬🧑🏿🔬👩🔬 Always wonderful to work with new/old collaborators and friends, including Drs Vokes, Schoenfeld (@adamjschoenfeld.bsky.social), Arbour (@kcarbourmd.bsky.social), Awad, Heist, Ardizzoni and Sholl
And thank you to the many co-authors for their hard work and wisdom on this journey. 🙏
/End
And thank you to the many co-authors for their hard work and wisdom on this journey. 🙏
/End
January 14, 2025 at 3:27 PM
🧑🏻🔬🧑🏿🔬👩🔬 Always wonderful to work with new/old collaborators and friends, including Drs Vokes, Schoenfeld (@adamjschoenfeld.bsky.social), Arbour (@kcarbourmd.bsky.social), Awad, Heist, Ardizzoni and Sholl
And thank you to the many co-authors for their hard work and wisdom on this journey. 🙏
/End
And thank you to the many co-authors for their hard work and wisdom on this journey. 🙏
/End
Meaning of #adenocarcinomas adenocarcinomas-belonging to malignant untumor originating in glandular, forming acinar structures epithelium - the word adenocarcinomas is used within the medicine-.. adenocarcinomas
December 25, 2024 at 11:40 PM
Meaning of #adenocarcinomas adenocarcinomas-belonging to malignant untumor originating in glandular, forming acinar structures epithelium - the word adenocarcinomas is used within the medicine-.. adenocarcinomas
Loan Vulliard, et al.: Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomas https://arxiv.org/abs/2510.05083 https://arxiv.org/pdf/2510.05083 https://arxiv.org/html/2510.05083
October 7, 2025 at 6:52 AM
Loan Vulliard, et al.: Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomas https://arxiv.org/abs/2510.05083 https://arxiv.org/pdf/2510.05083 https://arxiv.org/html/2510.05083
SCI members Dean Felsher, George Fisher & others found that 3 gastrointestinal #adenocarcinomas possess substantially different OS that appears differentially associated with HER2 status, mutp53, mutKRAS and MYC amplification. bit.ly/3CBLniU #GI25
Prognostic and biological divergence of upper gastrointestinal adenocarcinomas.
350Background: Esophageal (EAC), gastroesophageal junction (GEJ) or gastric (GAC) adenocarcinoma
share similar etiologies and treatment approaches. However, it is not clear if they
possess similar or ...
bit.ly
February 11, 2025 at 5:55 AM
SCI members Dean Felsher, George Fisher & others found that 3 gastrointestinal #adenocarcinomas possess substantially different OS that appears differentially associated with HER2 status, mutp53, mutKRAS and MYC amplification. bit.ly/3CBLniU #GI25
Ugh…Mom was still damaged but definitely nicer when we were kids. Dad’s protracted Alzheimer’s & her round robin with various, unrelated adenocarcinomas, surgery, and chemo really changed her into a different, very bitter and angry person. Understandable, I guess, but mostly miserable to be around.
November 11, 2023 at 9:18 PM
Ugh…Mom was still damaged but definitely nicer when we were kids. Dad’s protracted Alzheimer’s & her round robin with various, unrelated adenocarcinomas, surgery, and chemo really changed her into a different, very bitter and angry person. Understandable, I guess, but mostly miserable to be around.
NSAIDs drug use reduces risk of adenocarcinomas (40% in daily use ≥10 yr) of the esophagus in a pooled analysis http://awe.sm/5ovCv
Home - Awe.some
awe.sm
November 17, 2024 at 1:56 PM
NSAIDs drug use reduces risk of adenocarcinomas (40% in daily use ≥10 yr) of the esophagus in a pooled analysis http://awe.sm/5ovCv
Our analyses point to the importance of mutagenic context: KRAS G12C is enriched for the tobacco-associated SBS4 mutational signature, which is strongly correlated with tumor mutation burden across lung adenocarcinomas.
authors.elsevier.com/a/1ls3ocYZOi...
authors.elsevier.com/a/1ls3ocYZOi...
October 14, 2025 at 1:07 PM
Our analyses point to the importance of mutagenic context: KRAS G12C is enriched for the tobacco-associated SBS4 mutational signature, which is strongly correlated with tumor mutation burden across lung adenocarcinomas.
authors.elsevier.com/a/1ls3ocYZOi...
authors.elsevier.com/a/1ls3ocYZOi...
For adenocarcinomas, ESOPEC dethroned these results. Giving aggressive chemotherapy (FLOT) resulted in outcomes numerically comparable to the chemoradiation + immunotherapy from the CheckMate 577 study, but with the benefit of statistical significance.
(www.nejm.org/doi/full/10....)
(www.nejm.org/doi/full/10....)
June 1, 2025 at 7:30 PM
For adenocarcinomas, ESOPEC dethroned these results. Giving aggressive chemotherapy (FLOT) resulted in outcomes numerically comparable to the chemoradiation + immunotherapy from the CheckMate 577 study, but with the benefit of statistical significance.
(www.nejm.org/doi/full/10....)
(www.nejm.org/doi/full/10....)
The OncoAlert 🚨Newsletter NOW OUT Covering September November 28-Dec 5, 2024
REGISTER AT www.OncoAlert360.com OR https://buff.ly/48Xpgz0
✅FDA Approves Duvalumab in #SCLC 🫁🇺🇸
✅FDA ACCELERATED APPROVAL TO
ZENOCUTUZUMAB-ZBCO IN #NSCLC 🫁
✅Lung adenocarcinomas with mucinous & more
REGISTER AT www.OncoAlert360.com OR https://buff.ly/48Xpgz0
✅FDA Approves Duvalumab in #SCLC 🫁🇺🇸
✅FDA ACCELERATED APPROVAL TO
ZENOCUTUZUMAB-ZBCO IN #NSCLC 🫁
✅Lung adenocarcinomas with mucinous & more
December 5, 2024 at 2:40 PM
The OncoAlert 🚨Newsletter NOW OUT Covering September November 28-Dec 5, 2024
REGISTER AT www.OncoAlert360.com OR https://buff.ly/48Xpgz0
✅FDA Approves Duvalumab in #SCLC 🫁🇺🇸
✅FDA ACCELERATED APPROVAL TO
ZENOCUTUZUMAB-ZBCO IN #NSCLC 🫁
✅Lung adenocarcinomas with mucinous & more
REGISTER AT www.OncoAlert360.com OR https://buff.ly/48Xpgz0
✅FDA Approves Duvalumab in #SCLC 🫁🇺🇸
✅FDA ACCELERATED APPROVAL TO
ZENOCUTUZUMAB-ZBCO IN #NSCLC 🫁
✅Lung adenocarcinomas with mucinous & more
my happy place is visualizing Cheryl Hines being ravaged by cervical adenocarcinomas while a grisly goblin offers her alkaline water and contempt
February 27, 2025 at 6:37 AM
my happy place is visualizing Cheryl Hines being ravaged by cervical adenocarcinomas while a grisly goblin offers her alkaline water and contempt
(BioRxiv All) New proteomic signature in circulating extracellular vesicles from tumor-draining vein of lung adenocarcinomas patients: Identification of noninvasive prognostic biomarkers, allowing monitoring of frequently developed relapse in patients… http://dlvr.it/TFtV6z #BioRxiv #MassSpecRSS
October 30, 2024 at 2:07 PM
(BioRxiv All) New proteomic signature in circulating extracellular vesicles from tumor-draining vein of lung adenocarcinomas patients: Identification of noninvasive prognostic biomarkers, allowing monitoring of frequently developed relapse in patients… http://dlvr.it/TFtV6z #BioRxiv #MassSpecRSS
Do you know what is the role of #radiotherapy in #gastroesophageal adenocarcinomas?
▶️ this @myesmo.bsky.social GI oncology #podcast and discover more about that
open.spotify.com/episode/4vek...
▶️ this @myesmo.bsky.social GI oncology #podcast and discover more about that
open.spotify.com/episode/4vek...
Controversies in upper GI oncology: The role of radiotherapy in treatment of gastroesphageal adenocarcinoma
ESMO Podcasts · Episode
open.spotify.com
May 2, 2025 at 1:14 PM
Do you know what is the role of #radiotherapy in #gastroesophageal adenocarcinomas?
▶️ this @myesmo.bsky.social GI oncology #podcast and discover more about that
open.spotify.com/episode/4vek...
▶️ this @myesmo.bsky.social GI oncology #podcast and discover more about that
open.spotify.com/episode/4vek...
minha mãe tem 68 anos. 69, em novembro. e ela tá com câncer.
descobrimos recentemente que ela tem 2 adenocarcinomas no intestino. era caso de cirurgia urgente, o que ñ rolou pq ela tem problemas cardíacos, incluindo uma arritmia de longa data e má circulação de sangue no lado esquerdo do coração
+
descobrimos recentemente que ela tem 2 adenocarcinomas no intestino. era caso de cirurgia urgente, o que ñ rolou pq ela tem problemas cardíacos, incluindo uma arritmia de longa data e má circulação de sangue no lado esquerdo do coração
+
September 9, 2025 at 12:40 AM
minha mãe tem 68 anos. 69, em novembro. e ela tá com câncer.
descobrimos recentemente que ela tem 2 adenocarcinomas no intestino. era caso de cirurgia urgente, o que ñ rolou pq ela tem problemas cardíacos, incluindo uma arritmia de longa data e má circulação de sangue no lado esquerdo do coração
+
descobrimos recentemente que ela tem 2 adenocarcinomas no intestino. era caso de cirurgia urgente, o que ñ rolou pq ela tem problemas cardíacos, incluindo uma arritmia de longa data e má circulação de sangue no lado esquerdo do coração
+
Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomas #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2510.05083
https://arxiv.org/abs/2510.05083
October 7, 2025 at 7:01 AM
Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomas #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2510.05083
https://arxiv.org/abs/2510.05083
GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas https://www.biorxiv.org/content/10.1101/2024.12.03.626548v1
December 6, 2024 at 6:48 PM
GJB3, a gap junction gene, supports cell growth by mediating cystine uptake and regulating cellular stress pathways in SLC7A11 low adenocarcinomas https://www.biorxiv.org/content/10.1101/2024.12.03.626548v1
In-depth proteomic profiling of the extracellular matrix of pancreatic ductal adenocarcinomas identifies signatures correlating with lymphocyte infiltration 🧪 #PancreaticCancer www.biorxiv.org/content/10.1...
In-depth proteomic profiling of the extracellular matrix of pancreatic ductal adenocarcinomas identifies signatures correlating with lymphocyte infiltration
The extracellular matrix (ECM) is a complex assembly of proteins surrounding cells. It is a critical component of the tumor microenvironment that plays an active role in tumor progression and modulati...
www.biorxiv.org
September 4, 2025 at 1:59 PM
In-depth proteomic profiling of the extracellular matrix of pancreatic ductal adenocarcinomas identifies signatures correlating with lymphocyte infiltration 🧪 #PancreaticCancer www.biorxiv.org/content/10.1...