Zev Gartner
@zevgartner.bsky.social
Building tissues to understand how tissues build themselves
Reposted by Zev Gartner
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:22 AM
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Reposted by Zev Gartner
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology
McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.
www.nature.com
September 29, 2025 at 4:45 PM
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Reposted by Zev Gartner
First, check out my recent bioRxiv preprint w/ @oweinerlab.bsky.social: www.biorxiv.org/content/10.1...
We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!
We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!
A mechanical origin for implantation defects in embryos from aged females
Women over 35 experience a marked reduction in fertility. The origin of these fertility defects appears to reside in the implantation capacity of the embryo itself, but the mechanistic basis of this i...
www.biorxiv.org
October 1, 2025 at 6:21 PM
First, check out my recent bioRxiv preprint w/ @oweinerlab.bsky.social: www.biorxiv.org/content/10.1...
We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!
We find contractility shifts the proportion of implantation-competent embryos from young and aged females. Keep reading this for more info!
Reposted by Zev Gartner
Very excited to be co-organizing this meeting next February. Fellow collective behavior enthusiasts, this one is for you!
✨ How do bird flocks form or diseases emerge?
Join the brand-new EMBO | EMBL Symposium #EESCollectivity and explore how collective behaviours arise from fundamental principles across biological systems 🧬🦠🐒
💻 s.embl.org/ees26-01-bl
✒️ Submit your abstract by 18 Nov
Join the brand-new EMBO | EMBL Symposium #EESCollectivity and explore how collective behaviours arise from fundamental principles across biological systems 🧬🦠🐒
💻 s.embl.org/ees26-01-bl
✒️ Submit your abstract by 18 Nov
August 21, 2025 at 12:04 PM
Very excited to be co-organizing this meeting next February. Fellow collective behavior enthusiasts, this one is for you!
Reposted by Zev Gartner
Aria Huang's @azyhuang.bsky.social paper is out on beautiful embryonic kidney 3D cultures that branch properly and enable live defect analysis. She also finds intriguing effects of adhesion and stiffness on explant size, shape, and nephron formation - boundary conditions matter!
rdcu.be/eBSUK
rdcu.be/eBSUK
August 22, 2025 at 3:46 PM
Aria Huang's @azyhuang.bsky.social paper is out on beautiful embryonic kidney 3D cultures that branch properly and enable live defect analysis. She also finds intriguing effects of adhesion and stiffness on explant size, shape, and nephron formation - boundary conditions matter!
rdcu.be/eBSUK
rdcu.be/eBSUK
Reposted by Zev Gartner
🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨
“A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶
🔗 www.biorxiv.org/content/10.1...
#devbio #biophysics
🧵⤵️
“A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶
🔗 www.biorxiv.org/content/10.1...
#devbio #biophysics
🧵⤵️
June 11, 2025 at 4:47 PM
🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨
“A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶
🔗 www.biorxiv.org/content/10.1...
#devbio #biophysics
🧵⤵️
“A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶
🔗 www.biorxiv.org/content/10.1...
#devbio #biophysics
🧵⤵️
Reposted by Zev Gartner
One month left for ECRs to apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn,
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
April 23, 2025 at 1:34 PM
One month left for ECRs to apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn,
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
Reposted by Zev Gartner
Join us for our next #ForceTalk on "Mechanics of blastocyst morphogenesis" with Dr Jean-Leon Maitre @maitrejl.bsky.social of Institut Curie:
🗓️ 7 May 2025
🕒 15:00 - 16:00 BST
Online and open to all, link to join 👉 www.kcl.ac.uk/events/force...
#mechanobiology @kingsnmes.bsky.social
🗓️ 7 May 2025
🕒 15:00 - 16:00 BST
Online and open to all, link to join 👉 www.kcl.ac.uk/events/force...
#mechanobiology @kingsnmes.bsky.social
April 25, 2025 at 11:15 AM
Join us for our next #ForceTalk on "Mechanics of blastocyst morphogenesis" with Dr Jean-Leon Maitre @maitrejl.bsky.social of Institut Curie:
🗓️ 7 May 2025
🕒 15:00 - 16:00 BST
Online and open to all, link to join 👉 www.kcl.ac.uk/events/force...
#mechanobiology @kingsnmes.bsky.social
🗓️ 7 May 2025
🕒 15:00 - 16:00 BST
Online and open to all, link to join 👉 www.kcl.ac.uk/events/force...
#mechanobiology @kingsnmes.bsky.social
Reposted by Zev Gartner
Early-career researchers can apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn,
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
April 11, 2025 at 10:43 AM
Early-career researchers can apply for a funded place at our Workshop 'New Technologies for Studying and Reprogramming Development' organised by Alex Dunn,
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
@zevgartner.bsky.social , @adrianjacobo.bsky.social and Matthew Kutys.
📆Apply by 23 May
biologists.com/workshops/no...
#BiologistsWorkshops
Reposted by Zev Gartner
Many congratulations to @jcornwallscoones.bsky.social on the award of a Schmidt Science Fellowship
Now he just needs to find a lab to host him for his post-doc
www.crick.ac.uk/news/2025-04...
Now he just needs to find a lab to host him for his post-doc
www.crick.ac.uk/news/2025-04...
Crick PhD student awarded Schmidt Science Fellowship
Jake Cornwall Scoones, PhD student in the Developmental Dynamics Laboratory at the Francis Crick Institute, has been awarded a prestigious Schmidt Science Fellowship to support his research into how c...
www.crick.ac.uk
April 2, 2025 at 1:26 PM
Many congratulations to @jcornwallscoones.bsky.social on the award of a Schmidt Science Fellowship
Now he just needs to find a lab to host him for his post-doc
www.crick.ac.uk/news/2025-04...
Now he just needs to find a lab to host him for his post-doc
www.crick.ac.uk/news/2025-04...
Reposted by Zev Gartner
Since I started my PhD in 2013, I have been tantalised by a question: can we measure or evaluate the transcriptional and mechanical states of cells in a tissue at the same time? I pursued this question as a postdoc and then as a PI! A🧵on the answer we have found 👇:
March 17, 2025 at 12:53 PM
Since I started my PhD in 2013, I have been tantalised by a question: can we measure or evaluate the transcriptional and mechanical states of cells in a tissue at the same time? I pursued this question as a postdoc and then as a PI! A🧵on the answer we have found 👇:
1. Struggling to integrate single-cell datasets? Finding it hard to resolve clear differentiation trajectories? Reveal the underlying structure in your data with CONCORD.
March 20, 2025 at 6:08 PM
1. Struggling to integrate single-cell datasets? Finding it hard to resolve clear differentiation trajectories? Reveal the underlying structure in your data with CONCORD.
Reposted by Zev Gartner
Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org
March 10, 2025 at 1:28 PM
Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Predictable Engineering of Signal-Dependent Cis-Regulatory Elements
www.biorxiv.org/content/10.1...
1/11
Reposted by Zev Gartner
Congratulations Laura Avinyo! @lauavinyo.bsky.social and Heura Cardona! First paper of your PhD 🎉. doi.org/10.1242/dev.... Beautiful quantified trajectory of how the skeletal pattern of the gene Sox9 emerges during limb development. @embl.org @barcelonacollaboratorium.com
February 24, 2025 at 1:12 PM
Congratulations Laura Avinyo! @lauavinyo.bsky.social and Heura Cardona! First paper of your PhD 🎉. doi.org/10.1242/dev.... Beautiful quantified trajectory of how the skeletal pattern of the gene Sox9 emerges during limb development. @embl.org @barcelonacollaboratorium.com
Reposted by Zev Gartner
Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀
▶️ www.science.org/doi/10.1126/...
▶️ www.science.org/doi/10.1126/...
Material-like robotic collectives with spatiotemporal control of strength and shape
The vision of robotic materials—cohesive collectives of robotic units that can arrange into virtually any form with any physical properties—has long intrigued both science and fiction. Yet, this visio...
www.science.org
February 24, 2025 at 6:44 PM
Really excited to present the results of a great collaboration between our group @poldresden.bsky.social and Elliot Hawkes at @ucsantabarbara.bsky.social, which were just published in @science.org. A mix of physics, biology and robotics! 🤖 😀
▶️ www.science.org/doi/10.1126/...
▶️ www.science.org/doi/10.1126/...
Reposted by Zev Gartner
Excited that our new lab website is starting to come together - thanks to the team, particularly Pauline Marangoni and Zhulin Dixon, for assembling this, and stay tuned for additional updates ophirkleinlab.org
Home - Klein Lab
We are interested in understanding how organs form in the embryo and how they renew and regenerate in the adult. We research how development and regeneration
ophirkleinlab.org
January 26, 2025 at 7:07 PM
Excited that our new lab website is starting to come together - thanks to the team, particularly Pauline Marangoni and Zhulin Dixon, for assembling this, and stay tuned for additional updates ophirkleinlab.org
Reposted by Zev Gartner
Aria Huang's @azyhuang.bsky.social pre-print just came out on effects of adhesion and stiffness on global kidney explant size, shape and nephron forming efficiency. Along the way, she achieves beautiful 3D cultures that retain proper branching geometry, check it out!
biorxiv.org/cgi/content/...
biorxiv.org/cgi/content/...
Engineering kidney developmental trajectory using culture boundary conditions
Kidney explant cultures are traditionally carried out at air-liquid interfaces, which disrupts 3D tissue structure and limits the interpretation of developmental data. To overcome this limitation, we ...
biorxiv.org
December 17, 2024 at 7:27 PM
Aria Huang's @azyhuang.bsky.social pre-print just came out on effects of adhesion and stiffness on global kidney explant size, shape and nephron forming efficiency. Along the way, she achieves beautiful 3D cultures that retain proper branching geometry, check it out!
biorxiv.org/cgi/content/...
biorxiv.org/cgi/content/...
Reposted by Zev Gartner
Co-organizing the GRC Mammary Gland Biology and Neoplasia meeting this coming spring in Maine with Traci Lyons. Submit your abstracts for short talk consideration!
www.grc.org/mammary-glan...
www.grc.org/mammary-glan...
2025 Mammary Gland Biology Conference GRC
The 2025 Gordon Research Conference on Mammary Gland Biology will be held in Newry, Maine. Apply today to reserve your spot.
www.grc.org
November 11, 2024 at 4:37 PM
Co-organizing the GRC Mammary Gland Biology and Neoplasia meeting this coming spring in Maine with Traci Lyons. Submit your abstracts for short talk consideration!
www.grc.org/mammary-glan...
www.grc.org/mammary-glan...
Reposted by Zev Gartner
Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...
www.embl.org/about/info/c...
Mechanobiology across the tree of life
www.embl.org
November 20, 2024 at 4:49 PM
Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...
www.embl.org/about/info/c...
Reposted by Zev Gartner
My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social
doi.org/10.1242/dev....
Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....
doi.org/10.1242/dev....
Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....
November 19, 2024 at 6:09 PM
My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social
doi.org/10.1242/dev....
Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....
doi.org/10.1242/dev....
Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....
Right on the $$$
A stimulating workshop on the subject of Waddington Landscapes in Lyon last week, prompted me to compose some thoughts on dynamical landscapes, gene regulatory networks, and single cell transcriptomics
briscoelab.org/morphogenalia/
briscoelab.org/morphogenalia/
Briscoe Lab
Developmental Dynamics of Tissue Formation
briscoelab.org
November 13, 2024 at 2:14 PM
Right on the $$$