Eran Andrechek
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eranandrechek.bsky.social
Eran Andrechek
@eranandrechek.bsky.social
Mammary Development and Breast Cancer Lab at Michigan State University
Astrophotography, nature and Triathlon posts too.
https://lab.andrechek.com/ #bcsm #oncsky
Third preprint from the lab in as many weeks... this time, the loss of transcriptional control of early pregnancy by E2F5 results in alveolar defects. www.biorxiv.org/content/10.1...
Mammary Alveolar Proliferation and Differentiation During Early Pregnancy is Regulated by E2F5
The E2F transcription factors are well-established cell cycle regulators, but their roles in coordinating proliferation and differentiation remain poorly understood. Here, we investigated the function...
www.biorxiv.org
December 15, 2025 at 9:48 PM
So it got cold and clear with good seeing conditions for a few hours last night. The light of the full moon meant I had to shoot with a narrowband filter, and just a quick process shows that 4 hours on the horsehead is coming along nicely. The bright star is the bottom one on Orion’s Belt.
December 5, 2025 at 3:06 PM
Another preprint from the lab, this time using proximity labeling (BioID) to identify targets of the phosphatase PTPRH.

www.biorxiv.org/content/10.1...
Unraveling the role of receptor-like protein tyrosine phosphatase PTPRH in cell signaling regulation and biological processes of non-small cell lung cancer
The delicate balance of protein phosphorylation is often disrupted in cancers, with hyperactivity of kinases and inactivation of phosphatases driving cell proliferation and survival pathways. PTPRH, a...
www.biorxiv.org
December 4, 2025 at 2:01 PM
New preprint from the lab: www.biorxiv.org/content/10.1...

Publication will wait until the Oudin lab @madeleineoudin.bsky.social publishes theirs... invited them to talk at GRC Mammary and realized they'd scooped us! Their preprint is much more complete, already online and referenced in ours.
Neuronal innervation of breast cancer promotes metastatic dissemination
Metastasis is a leading cause of mortality in breast cancer patients, yet the signaling promoting metastatic dissemination is not completely understood. Prior literature implicates neuronal innervatio...
www.biorxiv.org
December 1, 2025 at 6:45 PM
Yes I’m listening to the ass Dean talking now… but I’m also processing my capture of the Triangulum Galaxy M33. #astrophotography
November 25, 2025 at 8:45 PM
Reposted by Eran Andrechek
It was a great pleasure to learn about a recent discovery in ecDNA biology that answers the most critical question on ecDNA maintenance! @nature.com Are you a non-scientist? No worries! My team wrote a lay-audience-friendly summary about this exciting research finding! Check it out! rdcu.be/eQMvM
November 20, 2025 at 5:57 PM
Reposted by Eran Andrechek
Multiple tenure-track faculty positions at the UNC Lineberger Comprehensive Cancer Center in Chapel Hill!
We seek creative scientists working in fundamental molecular, cellular, and computational areas. Basic and translational cancer research, all ranks.
unc.peopleadmin.com/postings/309...
Open Rank
The UNC Lineberger Comprehensive Cancer Center, in collaboration with departments in the School of Medicine and across the entire University of North Carolina at Chapel Hill, is seeking outstanding ca...
unc.peopleadmin.com
November 14, 2025 at 1:05 PM
Aurora quick pictures, really bright by eye! #astrophotography #aurora
November 13, 2025 at 3:36 AM
Aurora Timelapse in lower Michigan! #astrophotography #aurora
November 13, 2025 at 3:35 AM
Physiology experiments on my bike for fun… white is power, red is heart rate. Wonder if there is a wearable constant blood pressure monitor to integrate as well?
November 7, 2025 at 12:24 PM
It was my privilege today to host Peter Siegel from McGill to talk about his work on bone metastasis. Unpublished so won’t spoil it, but exciting work!
November 6, 2025 at 10:00 PM
The best part of useless university admin meetings is sitting at the back and processing telescope data from a few nights ago. Quick processing of 6.5 hours of Heart Nebula data… need to nod sagely to make the ass Dean feel important, but happy to see what my redcat51 did here.
November 5, 2025 at 4:55 PM
Reposted by Eran Andrechek
Victoria’s Secret Global Fund for Women’s Cancers Career Development Award 2025: Advancing Research in Breast and Gynecologic Cancers

oncodaily.com/insight/vict...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #GynOnc
Victoria’s Secret Global Fund for Women’s Cancers Career Development Award 2025: Advancing Research in Breast and Gynecologic Cancers - OncoDaily
Victoria’s Secret Global Fund for Women’s Cancers Career Development Award 2025: Advancing Research in Breast and Gynecologic Cancers / Breast Cancer
oncodaily.com
November 4, 2025 at 8:35 PM
At first I thought my camera had a glitch, but after reviewing individual frames, it seems like there was a whole train of satellites that messed up my Comet Lemmon shot! #astrophotography #A6Lemmon
October 27, 2025 at 4:13 PM
Best part of having a meeting on the other side of campus is the shortcut through the gardens this time of year.
October 21, 2025 at 6:53 PM
Chances of getting Blue Jay tix for World Series seem rather low!
October 21, 2025 at 2:05 PM
Knew it would be coming, but the cancellation of study section is rough. Less than 24 hours notice that we're cancelled. Hard as a reviewer when you prepped for the grants and hard knowing we have two submissions of our own that were scheduled for review that are now just waiting.
October 20, 2025 at 8:24 PM
In this tough grant climate, I'm incredibly proud that we've now got 4 students in the lab supported by various fellowships! Very grateful to @michiganstateu.bsky.social and the Jenison Fund for picking up the students that had fellowships terminated .
October 20, 2025 at 5:14 PM
A few days in Switzerland before the Basel Breast Cancer meeting. Just love the Alps!
October 13, 2025 at 2:54 PM
Most scenic bike ride ever… from Interlaken to Stechelberg, locked bikes and took the tram to Murren, then back.
October 10, 2025 at 8:06 PM
Early yesterday morning I caught Comet Lemmon going past the Little Pinwheel Galaxy. At mag 6.2 it is rapidly getting brighter. 15 x 5 min images on Redcat51 with ASI533. #comet #Lemmon #astrophotography #cometlemmon
October 6, 2025 at 4:42 PM
A once every 15 years thing… Titan is transiting in front of Saturn. In a few minutes I’m hoping to catch the shadow as well. #astrophotography #saturn
October 6, 2025 at 4:11 AM
Happy International Observe the Moon Night!
October 5, 2025 at 2:35 AM
Always get more nervous for my student talks instead of my own… but sitting at the back I can see a lot of heads nodding in agreement for Anthony’s talk about our BioID data.
September 25, 2025 at 3:39 PM
Live view on the telescope while sitting on the couch… still amazes me how many advances in the past few years for backyard telescopes! M31 with a 5 min exposure.
September 18, 2025 at 2:33 AM