Yale Cell Biology
@yalecellbiology.bsky.social
Dr. Phyllis Hanson was recently awarded the Sir Bernard Katz Award for excellence in exocytosis and endocytosis research. Congratulations, @pihanson.bsky.social !
medicine.yale.edu/cellbio/news...
medicine.yale.edu/cellbio/news...
Dr. Phyllis Hanson Honored with Katz Award
We are excited to share that Dr. Phyllis Hanson, a former postdoctoral fellow in Yale’s Cell Biology Department, was recently awarded the 2026 Sir Bernard Katz
medicine.yale.edu
November 5, 2025 at 5:18 PM
Dr. Phyllis Hanson was recently awarded the Sir Bernard Katz Award for excellence in exocytosis and endocytosis research. Congratulations, @pihanson.bsky.social !
medicine.yale.edu/cellbio/news...
medicine.yale.edu/cellbio/news...
Exciting new work from Xiaolei Su’s lab showing how engineering chimeric antigen receptors (CARs) with intrinsically disordered regions (IDRs) increases the efficacy of CAR-T cell cytotoxicity against cancer cells!
The fusion of intrinsically disordered regions to CARs enhances CAR-T signaling by inducing CAR condensation and enhances CAR sensitivity to low-antigen-expressing cancer cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers - Nature Chemical Biology
Low-antigen-expressing cancers are a challenge to existing chimeric antigen receptor (CAR)-T cell-based therapies. Now, it has been shown that fusion of intrinsically disordered regions to CARs induces CAR condensation and enhances antigen sensitivity and killing activity of CAR-T cells.
www.nature.com
October 29, 2025 at 4:02 PM
Exciting new work from Xiaolei Su’s lab showing how engineering chimeric antigen receptors (CARs) with intrinsically disordered regions (IDRs) increases the efficacy of CAR-T cell cytotoxicity against cancer cells!
Reposted by Yale Cell Biology
We're hiring new faculty! Looking for talented scientists that are interested in pushing the boundaries of Cell Biology. Please spread the word!
September 4, 2025 at 2:22 PM
We're hiring new faculty! Looking for talented scientists that are interested in pushing the boundaries of Cell Biology. Please spread the word!
Reposted by Yale Cell Biology
Interested in metabolism? So are we! My lab has been exploring the cell biology of energy metabolism in the nervous system, and we are looking for postdocs. Cool sensors and microscopy, great work environment. Please help me spread the word!
October 2, 2025 at 12:15 AM
Interested in metabolism? So are we! My lab has been exploring the cell biology of energy metabolism in the nervous system, and we are looking for postdocs. Cool sensors and microscopy, great work environment. Please help me spread the word!
Reposted by Yale Cell Biology
We're still accepting submissions for our next special issue:
Cell Biology of the Nucleus
Guest edited by @abbybuch.bsky.social and Megan King @luskinglab.bsky.social.
Submission deadline: 3 November
journals.biologists.com/jcs/pages/nu...
#cellbiology #nucleus #notforprofit #freetopublish
Cell Biology of the Nucleus
Guest edited by @abbybuch.bsky.social and Megan King @luskinglab.bsky.social.
Submission deadline: 3 November
journals.biologists.com/jcs/pages/nu...
#cellbiology #nucleus #notforprofit #freetopublish
September 30, 2025 at 9:26 AM
We're still accepting submissions for our next special issue:
Cell Biology of the Nucleus
Guest edited by @abbybuch.bsky.social and Megan King @luskinglab.bsky.social.
Submission deadline: 3 November
journals.biologists.com/jcs/pages/nu...
#cellbiology #nucleus #notforprofit #freetopublish
Cell Biology of the Nucleus
Guest edited by @abbybuch.bsky.social and Megan King @luskinglab.bsky.social.
Submission deadline: 3 November
journals.biologists.com/jcs/pages/nu...
#cellbiology #nucleus #notforprofit #freetopublish
Interesting synthetic lethality during mouse development of two bridge-like lipid transfer proteins that are thought to localize in distinct compartments...new work from @pdc-lab.bsky.social in collaboration with @dianekrause.bsky.social:
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Impaired hematopoiesis and embryonic lethality at midgestation of mice lacking both lipid transfer proteins VPS13A and VPS13C
VPS13A and VPS13C are bridge-like lipid transport proteins with distinct subcellular localization and function, and their absence is linked with chorea-acanthocytosis and Parkinson's disease, respecti...
journals.plos.org
September 30, 2025 at 9:19 PM
Interesting synthetic lethality during mouse development of two bridge-like lipid transfer proteins that are thought to localize in distinct compartments...new work from @pdc-lab.bsky.social in collaboration with @dianekrause.bsky.social:
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Yale Cell Biology
CRN Team De Camilli reveals a new molecular mechanism that regulates cystine efflux from lysosomes. This work is relevant to #Parkinsons research, as recent studies show JIP4 is downstream of LRRK2.
🔗 Read their #preprint: bit.ly/4l8zCkf
✏️ @shawnferguson.bsky.social @laylanassar.bsky.social
🔗 Read their #preprint: bit.ly/4l8zCkf
✏️ @shawnferguson.bsky.social @laylanassar.bsky.social
August 12, 2025 at 5:09 PM
CRN Team De Camilli reveals a new molecular mechanism that regulates cystine efflux from lysosomes. This work is relevant to #Parkinsons research, as recent studies show JIP4 is downstream of LRRK2.
🔗 Read their #preprint: bit.ly/4l8zCkf
✏️ @shawnferguson.bsky.social @laylanassar.bsky.social
🔗 Read their #preprint: bit.ly/4l8zCkf
✏️ @shawnferguson.bsky.social @laylanassar.bsky.social
Reposted by Yale Cell Biology
Join us this Thursday for our mini-symposium with the membrane trafficking webinar series
Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
focalplane.biologists.com/2025/09/16/f...
Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
focalplane.biologists.com/2025/09/16/f...
FocalPlane features... membrane trafficking - FocalPlane
FocalPlane features... membrane trafficking - News
focalplane.biologists.com
September 22, 2025 at 12:17 PM
Join us this Thursday for our mini-symposium with the membrane trafficking webinar series
Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
focalplane.biologists.com/2025/09/16/f...
Featuring talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and a keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
focalplane.biologists.com/2025/09/16/f...
Reposted by Yale Cell Biology
Thanks to Min Wu from Yale Cell Bio for a great talk today about information processing at the immune cell surface in the second edition of our new PEB / QBio seminar series. Yale friends, we hope you join us at future talks in this series, happening on Fridays at 11AM!
September 19, 2025 at 3:48 PM
Thanks to Min Wu from Yale Cell Bio for a great talk today about information processing at the immune cell surface in the second edition of our new PEB / QBio seminar series. Yale friends, we hope you join us at future talks in this series, happening on Fridays at 11AM!
Did you know that all nuclear pore complexes (NPCs) are not the same? @luskinglab.bsky.social propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Nuclear mechanics as a determinant of nuclear pore complex plasticity - Nature Cell Biology
In this Review, Lusk et al. discuss emerging insights into nuclear pore complex variability with regard to composition and dilation state, and propose nuclear mechanics as a key determinant of driving...
www.nature.com
September 19, 2025 at 3:50 PM
Did you know that all nuclear pore complexes (NPCs) are not the same? @luskinglab.bsky.social propose a new hypothesis for how nuclear mechanics may impact the compositional plasticity of NPCs with implications for tissue-specific diseases caused by NPC dysfunction.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Happy Post Doc Appreciation Week! We are so grateful to all our post docs for the research expertise, leadership, and mentorship they bring to our department! #NPAW2025 #postdocappreciationweek
September 19, 2025 at 1:13 PM
Happy Post Doc Appreciation Week! We are so grateful to all our post docs for the research expertise, leadership, and mentorship they bring to our department! #NPAW2025 #postdocappreciationweek
Reposted by Yale Cell Biology
Next Thursday Sept 25 (4-6pm CET) we have our first #FocalPlaneFeatures together with our #membranetrafficking community! Thanks to all who submitted such exciting abstracts. The final program is out, featuring a keynote by Gillian Griffiths. Register here: focalplane.biologists.com/2025/09/16/f...
September 16, 2025 at 4:03 PM
Next Thursday Sept 25 (4-6pm CET) we have our first #FocalPlaneFeatures together with our #membranetrafficking community! Thanks to all who submitted such exciting abstracts. The final program is out, featuring a keynote by Gillian Griffiths. Register here: focalplane.biologists.com/2025/09/16/f...
@pdc-lab.bsky.social lab does it again - new insight into bridge-like transport proteins - this time as part of the curious CASM pathway.
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM | The EMBO Journal www.embopress.org/doi/full/10....
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM | The EMBO Journal www.embopress.org/doi/full/10....
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM | The EMBO Journal
imageimageLysosomes can be damaged by diverse cellular stresses, triggering cellular responses
that repair or remove them. This manuscript shows that BLTP3A, a Rab7 effector, is
first shed from lysoso...
www.embopress.org
September 15, 2025 at 8:33 PM
@pdc-lab.bsky.social lab does it again - new insight into bridge-like transport proteins - this time as part of the curious CASM pathway.
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM | The EMBO Journal www.embopress.org/doi/full/10....
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM | The EMBO Journal www.embopress.org/doi/full/10....
Reposted by Yale Cell Biology
Registration is open for our Imaging Cell Dynamics meeting.
Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging.
For more info: www.biologists.com/meetings/jcs...
Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging.
For more info: www.biologists.com/meetings/jcs...
September 15, 2025 at 1:21 PM
Registration is open for our Imaging Cell Dynamics meeting.
Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging.
For more info: www.biologists.com/meetings/jcs...
Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social & Giulia Zanetti, the meeting will focus on the interface between cell biology and imaging.
For more info: www.biologists.com/meetings/jcs...
Reposted by Yale Cell Biology
Learn more about all the 2025 #LaskerAward winners—Dirk Görlich & Steven L. McKnight; Michael J. Welsh, Jesús (Tito) González, & Paul A. Negulescu; Lucy Shapiro 🧪
#Lasker2025
📖: laskerfoundation.org/winners/2025...
👀: laskerfoundation.org/the-2025-las...
#Lasker2025
📖: laskerfoundation.org/winners/2025...
👀: laskerfoundation.org/the-2025-las...
2025 Winners - Lasker Foundation
winners
laskerfoundation.org
September 11, 2025 at 7:34 PM
Learn more about all the 2025 #LaskerAward winners—Dirk Görlich & Steven L. McKnight; Michael J. Welsh, Jesús (Tito) González, & Paul A. Negulescu; Lucy Shapiro 🧪
#Lasker2025
📖: laskerfoundation.org/winners/2025...
👀: laskerfoundation.org/the-2025-las...
#Lasker2025
📖: laskerfoundation.org/winners/2025...
👀: laskerfoundation.org/the-2025-las...
Reposted by Yale Cell Biology
ICE and DHS have proposed capping F and J visas at 4 years, threatening international students and postdocs who drive U.S. research. Share your comments to oppose this harmful policy: www.ascb.org/science-poli...
White House Proposes Shorter F and J Visa Terms - ASCB
U.S. Immigration and Customs Enforcement (ICE) and the Department of Homeland Security (DHS) have published a notice in the Federal Register proposing changes to regulations that would significantly s...
www.ascb.org
September 10, 2025 at 3:52 PM
ICE and DHS have proposed capping F and J visas at 4 years, threatening international students and postdocs who drive U.S. research. Share your comments to oppose this harmful policy: www.ascb.org/science-poli...
More insight into the ever expanding roles of bridge-like lipid transfer proteins from @pdc-lab.bsky.social !
Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics url: rupress.org/jcb/article/...
Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics url: rupress.org/jcb/article/...
Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics | Journal of Cell Biology | Rockefeller University Press
Dai et al. report the localization of BLTP2 in different human cell types and reveal binding partners that mediate its tethering to the PM and to PM-connec
rupress.org
September 5, 2025 at 2:12 PM
More insight into the ever expanding roles of bridge-like lipid transfer proteins from @pdc-lab.bsky.social !
Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics url: rupress.org/jcb/article/...
Multiple interactions recruit BLTP2 to ER-PM contacts to control plasma membrane dynamics url: rupress.org/jcb/article/...
Who knew the ER was under tension? Innovative work from @schliekerlab.bsky.social with help from @berrolab.bsky.social
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation url: rupress.org/jcb/article/...
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation url: rupress.org/jcb/article/...
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation | Journal of Cell Biology | Rockefeller University Press
Naughton et al. establish that the ER experiences forces in the piconewton range across the ER lumen and identify NOMO as a force-bearing transmembrane pro
rupress.org
September 4, 2025 at 5:28 PM
Who knew the ER was under tension? Innovative work from @schliekerlab.bsky.social with help from @berrolab.bsky.social
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation url: rupress.org/jcb/article/...
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation url: rupress.org/jcb/article/...
Check out the latest issue of JCB for new work from @luskinglab.bsky.social - a powerful microscopy tool developed here by the Bewersdorf lab that is providing new views of NPCs.
Visualizing nuclear pore complex plasticity with pan-expansion microscopy url: rupress.org/jcb/article-...
Visualizing nuclear pore complex plasticity with pan-expansion microscopy url: rupress.org/jcb/article-...
September 4, 2025 at 2:26 PM
Check out the latest issue of JCB for new work from @luskinglab.bsky.social - a powerful microscopy tool developed here by the Bewersdorf lab that is providing new views of NPCs.
Visualizing nuclear pore complex plasticity with pan-expansion microscopy url: rupress.org/jcb/article-...
Visualizing nuclear pore complex plasticity with pan-expansion microscopy url: rupress.org/jcb/article-...
We're hiring new faculty! Looking for talented scientists that are interested in pushing the boundaries of Cell Biology. Please spread the word!
September 4, 2025 at 2:22 PM
We're hiring new faculty! Looking for talented scientists that are interested in pushing the boundaries of Cell Biology. Please spread the word!