Yale Biomedical Imaging Institute
yalebiomedimaging.bsky.social
Yale Biomedical Imaging Institute
@yalebiomedimaging.bsky.social
Yale Biomedical Imaging Institute is an interdisciplinary research institute transforming our understnading of health and disease through biomedical imaging.
Reposted by Yale Biomedical Imaging Institute
Update - the final peer-reviewed version of the manuscript is out!
We examined combined utility of PET/MR pancreas imaging metrics in type 2 diabetes.
@yalebiomedimaging.bsky.social

www.frontiersin.org/journals/end...
Frontiers | Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET
ObjectiveTo determine if combining PET-derived beta-cell mass (BCM) estimates with MRI-based morphology metrics improves the prediction of beta-cell function...
www.frontiersin.org
December 18, 2025 at 3:31 PM
Reposted by Yale Biomedical Imaging Institute
How are advanced PET imaging biomarkers 🔬 enhancing our ability to study neuroimmune dynamics 🧠🛡️ in psychiatric illness 😔 to refine diagnostics 🩺 and discover new therapies ✨?

Find out here 👇
Imaging Neuroimmune Dysfunction: From TSPO to Emerging PET Targets
Dysregulation of the neuroimmune system is increasingly recognized as a key contributor to psychiatric illness, yet its complexity and the limitations of current methodologies have hindered a clear…
www.biologicalpsychiatryjournal.com
November 28, 2025 at 1:01 PM
New article from Dr. Johnson: "Radiologist-Validated Automatic Lumbar T1-Weighted Spinal MRI Segmentation Tool via an Attention U-Net Algorithm" supports consistent measurements and future quantitative spine applications. mdpi.com/3612296 #mdpidiagnostics
mdpi.com
December 4, 2025 at 4:07 PM
We've developed HYDRA-OL phantoms using high-resolution #3Dprinting to enhance brain #PETimaging system performance assessment. These phantoms offer superior spatial resolution for next-gen brain PET systems and improved gray and white matter contrast.
Read more:
ieeexplore.ieee.org/document/112...
December 4, 2025 at 4:06 PM
Director Georges El Fakhri presented on imaging approaches for #NETS Awareness Day 2025. See link for a full video of the Smilow Shares seminar, highlighting the diagnosis, treatment, and awareness of neuroendocrine tumors: m.yale.edu/dctm
NETS Awareness Day 2025
On November 10, 2025, Dr. Pamela Kunz hosted a Smilow Shares in honor of NETS Awareness Day.
m.yale.edu
November 13, 2025 at 5:51 PM
The 3rd annual Nonlinear Parameter Parley and Pub Crawl, held at Seoul National University Hospital on May 30, brought together PET kinetic modeling experts. New topics included time-varying models & spatial drug occupancy #NLPPPC #PETImaging #BrainPET2025
medicine.yale.edu/biomedical-i...
The NLPPPC workshop
The third Nonlinear Parameter Parley (NLPP 3.0) was held on May 30, 2025, at Seoul National University Hospital. Organized by Dr. Su Jin Kim, Prof. Evan Morris,
medicine.yale.edu
November 11, 2025 at 6:36 PM
Reposted by Yale Biomedical Imaging Institute
A brain mapping approach inspired by caricature art, which emphasizes individual differences in neural connections, enhances prediction of traits such as age, IQ, and emotional processing. doi.org/g989wc
Caricature-inspired brain mapping method sharpens forecasts of cognitive and emotional traits
Caricature artists exaggerate distinctive features of an individual, deepening a cleft chin or multiplying freckles. Yale researchers have now applied a similar approach to maps of neural connections, emphasizing individual differences to see if they yield useful information.
medicalxpress.com
November 5, 2025 at 9:09 PM
In a dual-tracer PET study of #PD, we found patterns across disease stages between DAT availability and synaptic density in nigrostriatal regions. Understanding dopaminergic vs. presynaptic degeneration in PD could advance disease insight
movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
Measuring Dopamine Transporter Availability and Synaptic Density in Parkinson's Disease: A Dual‐Tracer Positron Emission Tomography Imaging Study
Background 18F-FE-PE2I is a highly selective dopamine transporter (DAT) positron emission tomography (PET) radioligand, whereas 11C-UCB-J targets synaptic vesicle glycoprotein 2A (SV2A), enabling th...
movementdisorders.onlinelibrary.wiley.com
October 23, 2025 at 6:29 PM
Thanks to the long axial FOV and high resolution of the #NeuroEXPLORER, our team has shown major improvements in image-derived blood time-activity curves for brain PET, reducing the need for arterial sampling and enabling easier kinetic modeling.

jnm.snmjournals.org/content/earl...
Carotid Artery Image-Derived Blood Time–Activity Curves on the NeuroEXPLORER: Initial Multitracer Validation Against Arterial Sampling
Image-derived input functions are noninvasive alternatives to arterial blood sampling for PET kinetic modeling, allowing one to measure the whole-blood time–activity curve (BTAC). However, partial-vol...
jnm.snmjournals.org
October 22, 2025 at 7:37 PM
Dr. Jason Johnson and collaborators developed the world’s first DL model specifically designed to segment ultra-high resolution brain MRI. The new GA-MS-#UNet++ model uses advanced attention mechanisms to unlock the potential to detect subtle brain changes

www.mdpi.com/2306-5354/12...
October 22, 2025 at 7:29 PM
Check out YBII at @miccaisociety.bsky.social

#MICCAI2025:
Geometry-Guided Local Alignment for Multi-View Visual Language Pre-Training in Mammography

Yuexi Du, Lihui Chen, Nicha C. Dvornek
papers.miccai.org/miccai-2025/...
September 25, 2025 at 1:54 PM
Reposted by Yale Biomedical Imaging Institute
This developmental trajectory is consistent across four datasets, with deviations from this trajectory associated with poorer executive function. Girls also peaked earlier than boys. @yalebiomedimaging.bsky.social @yaleschoolofmed.bsky.social

sciencedirect.com/science/arti...
Variation in moment-to-moment brain state engagement follows a consistent trajectory during development
Neural variability, or variation in brain signals, facilitates dynamic brain responses to ongoing demands. This flexibility is important during develo…
sciencedirect.com
September 24, 2025 at 3:45 PM
A new #PET tracer can provide insights into how spinal cord injuries affect not only the spinal cord, but also the brain, according to our new research published in @journalofnucmed.bsky.social

snmmi.org/Web/News/Art...
Novel PET Tracer Detects Synaptic Changes in Spinal Cord and Brain After Spinal Cord Injury
A new PET tracer can provide insights into how spinal cord injuries affect not only the spinal cord, but also the brain, according to new research published in The Journal of Nuclear Medicine
snmmi.org
September 12, 2025 at 4:17 PM
Yale School of Medicine announces the launch of the Yale Biomedical Imaging Institute. The Institute will unite leading experts in imaging technology, clinical translation, and data science.

Discover more about the Institute and learn how to get involved:

m.yale.edu/c7ws
Yale Announces New Biomedical Imaging Institute
The Yale Biomedical Imaging Institute will drive transformative advancements in both basic science and clinical translation.
m.yale.edu
July 10, 2025 at 2:37 PM