Jason Bini, PhD
@sciencedrbini.bsky.social
Assistant Professor, Yale PET Center, Radiology and Biomedical Imaging
Research: diabetes, obesity, metabolism, endocrinology. PET imaging of pancreas, liver, adipose and brain.
(opinions my own)
Family 👪🐶🐶, swimming, cycling, trail running, 🎸
Research: diabetes, obesity, metabolism, endocrinology. PET imaging of pancreas, liver, adipose and brain.
(opinions my own)
Family 👪🐶🐶, swimming, cycling, trail running, 🎸
Pinned
If you have patients or folks you know who have recently been diagnosed with stage 1 or 2 Type 1 Diabetes in the Northeast. Have them contact us! Recruiting for longitudinal PET/MRI studies!
Reposted by Jason Bini, PhD
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice
Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...
www.biorxiv.org
October 31, 2025 at 1:52 PM
Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.
Now, do it all again, longitudinally….
So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻
www.biorxiv.org/content/10.1...
Not entirely convinced reviewers 1 and 2 even read our manuscript...
October 30, 2025 at 4:01 PM
Not entirely convinced reviewers 1 and 2 even read our manuscript...
Imagine my excitement reading this title only to find out it's not *that* IPA 🍺😂
October 28, 2025 at 11:19 AM
Imagine my excitement reading this title only to find out it's not *that* IPA 🍺😂
Hey that's us! First official Bini lab preprint 🎉
Morphological and Functional Alterations in Type 2 Diabetes Pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET https://www.medrxiv.org/content/10.1101/2025.10.13.25337899v1
October 16, 2025 at 3:49 PM
Hey that's us! First official Bini lab preprint 🎉
Reposted by Jason Bini, PhD
A birthday is a good time to reflect! To mark SPM @ 30, this month's issue of Cerebral Cortex features deeply insightful commentaries on neuroimaging analysis from Ed Bullmore, Peter Bandettini, Peter Fox, Pedro Valdes-Sosa, Klaas Enno Stephan, Viktor Jirsa, et al [1/2] academic.oup.com/cercor/issue
Issues | Cerebral Cortex | Oxford Academic
Publishes papers on the development, organization, plasticity, and function of the cerebral cortex, including the hippocampus.
academic.oup.com
September 16, 2025 at 8:16 AM
A birthday is a good time to reflect! To mark SPM @ 30, this month's issue of Cerebral Cortex features deeply insightful commentaries on neuroimaging analysis from Ed Bullmore, Peter Bandettini, Peter Fox, Pedro Valdes-Sosa, Klaas Enno Stephan, Viktor Jirsa, et al [1/2] academic.oup.com/cercor/issue
If you haven't seen it yet, check out our article highlighted Up Front as an editors pick in the @DiabetologiaJnl September issue!
Up front & free to read in our Sept issue #editorspicks: Measurement of brain glucose metabolism in obesity and diabetes link.springer.com/article/10.1...
Measurement of brain glucose metabolism in obesity and diabetes - Diabetologia
The brain consumes a large amount of glucose to fuel its high metabolic demands. Understanding brain glucose metabolism is critical for understanding the brain’s normal physiology and the pathological...
link.springer.com
September 9, 2025 at 4:47 PM
If you haven't seen it yet, check out our article highlighted Up Front as an editors pick in the @DiabetologiaJnl September issue!
Reposted by Jason Bini, PhD
The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.
With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency
Republicans on spending committee push back against proposed reorganization and overhead cuts
scim.ag
July 31, 2025 at 9:37 PM
The National Institutes of Health’s budget, and structure, would be preserved under a Senate bill for the 2026 fiscal year.
Reposted by Jason Bini, PhD
NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com/2025/07/29/n...
www.statnews.com/2025/07/29/n...
NIH is shrinking the number of research projects it funds due to a new Trump policy
NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com
July 29, 2025 at 1:34 PM
NIH plans to shrink the share of grant applications it will award for the remainder of the fiscal year, in some cases by more than half.
www.statnews.com/2025/07/29/n...
www.statnews.com/2025/07/29/n...
Reposted by Jason Bini, PhD
"Concerns are rising that President Donald Trump’s administration is finding new ways to shrink the U.S. biomedical research enterprise [right now]"
Great article from @jocelynkaiser.bsky.social at @science.org
🧪
Great article from @jocelynkaiser.bsky.social at @science.org
🧪
Odds of winning NIH grants plummet as new funding policy and spending delays bite
Funding multiyear grants up front will sharply cut number of investigators receiving awards
www.science.org
July 29, 2025 at 1:22 AM
"Concerns are rising that President Donald Trump’s administration is finding new ways to shrink the U.S. biomedical research enterprise [right now]"
Great article from @jocelynkaiser.bsky.social at @science.org
🧪
Great article from @jocelynkaiser.bsky.social at @science.org
🧪
Reposted by Jason Bini, PhD
🚨 Required reading for every scientist, academic admin, and member of Congress 🚨
The shift to multi-year funding is a Trojan Horse designed to cannibalize NIH funding with zero congressional oversight
The effects will be immediate. paylines will crater, labs will shutter, Americans will suffer. 🧪
The shift to multi-year funding is a Trojan Horse designed to cannibalize NIH funding with zero congressional oversight
The effects will be immediate. paylines will crater, labs will shutter, Americans will suffer. 🧪
July 29, 2025 at 12:34 AM
🚨 Required reading for every scientist, academic admin, and member of Congress 🚨
The shift to multi-year funding is a Trojan Horse designed to cannibalize NIH funding with zero congressional oversight
The effects will be immediate. paylines will crater, labs will shutter, Americans will suffer. 🧪
The shift to multi-year funding is a Trojan Horse designed to cannibalize NIH funding with zero congressional oversight
The effects will be immediate. paylines will crater, labs will shutter, Americans will suffer. 🧪
Very excited for this review to be out! A dive into PET/MRS techniques for measuring brain glucose concentrations and cerebral metabolic rate of glucose in the context of diabetes and obesity. #neuroimaging #obesity #diabetes #metabolism #neuroendocrinology
link.springer.com/article/10.1...
link.springer.com/article/10.1...
July 28, 2025 at 5:01 PM
Very excited for this review to be out! A dive into PET/MRS techniques for measuring brain glucose concentrations and cerebral metabolic rate of glucose in the context of diabetes and obesity. #neuroimaging #obesity #diabetes #metabolism #neuroendocrinology
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Jason Bini, PhD
DOGE is now reviewing every NIH grant that goes out, I reported last week.
That review is AI-driven and is screening for DEI, trans health, China, vaccine hesitancy, and the institutions to whom Trump has blocked funding, @hannahnatanson.bsky.social reports.
Gift link: wapo.st/3HhnPSt
That review is AI-driven and is screening for DEI, trans health, China, vaccine hesitancy, and the institutions to whom Trump has blocked funding, @hannahnatanson.bsky.social reports.
Gift link: wapo.st/3HhnPSt
June 2, 2025 at 6:17 PM
DOGE is now reviewing every NIH grant that goes out, I reported last week.
That review is AI-driven and is screening for DEI, trans health, China, vaccine hesitancy, and the institutions to whom Trump has blocked funding, @hannahnatanson.bsky.social reports.
Gift link: wapo.st/3HhnPSt
That review is AI-driven and is screening for DEI, trans health, China, vaccine hesitancy, and the institutions to whom Trump has blocked funding, @hannahnatanson.bsky.social reports.
Gift link: wapo.st/3HhnPSt
Reposted by Jason Bini, PhD
Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post.
www.washingtonpost.com/opinions/202...
www.washingtonpost.com/opinions/202...
Opinion | Universities and the government: Which needs the other more?
From public health to high-tech innovation, universities are the workhorses of national progress.
www.washingtonpost.com
June 3, 2025 at 12:01 PM
Universities are not passive beneficiaries of government largesse. It is the federal government that depends on universities to conduct the research that keeps our nation healthy, safe and economically competitive.I discuss in the Washington Post.
www.washingtonpost.com/opinions/202...
www.washingtonpost.com/opinions/202...
Reposted by Jason Bini, PhD
The university endowment tax in the Republican/Trump economic plan sets a dangerous precedent of the government slapping excessive taxes on institutions it disagrees with ideologically. It also will cause cuts in jobs, financial aid and research funding. wapo.st/3HiYtDv
May 29, 2025 at 4:27 PM
The university endowment tax in the Republican/Trump economic plan sets a dangerous precedent of the government slapping excessive taxes on institutions it disagrees with ideologically. It also will cause cuts in jobs, financial aid and research funding. wapo.st/3HiYtDv
Reposted by Jason Bini, PhD
The "Make America Health Again" Report has the word "obesity" in it 51 times and yet the primary US institute that researches the impact and new treatments for obesity (NIDDK) would be sure to have their budget cut under the current spending bill or the White House recs (40% cut to the NIH budget).
May 29, 2025 at 3:34 PM
The "Make America Health Again" Report has the word "obesity" in it 51 times and yet the primary US institute that researches the impact and new treatments for obesity (NIDDK) would be sure to have their budget cut under the current spending bill or the White House recs (40% cut to the NIH budget).
It's not a fully formed thought but someone needs to connect the collapse of universities/colleges all across the country with the collapse of the sports (scholarships) industrial complex. I would guess a HUGE economy is kids sports in hopes of playing big time college sports.
May 29, 2025 at 12:49 PM
It's not a fully formed thought but someone needs to connect the collapse of universities/colleges all across the country with the collapse of the sports (scholarships) industrial complex. I would guess a HUGE economy is kids sports in hopes of playing big time college sports.
Reposted by Jason Bini, PhD
Could be huge. Especially for those terminated in the anti-DEI purge.
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
NOT-OD-25-115: Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibility for Mentored Career Development Award When an Award Ended Ear...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibi...
grants.nih.gov
May 28, 2025 at 10:56 PM
Could be huge. Especially for those terminated in the anti-DEI purge.
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
Reposted by Jason Bini, PhD
Sworn testimony of NIH officials and internal emails reveal just how much DOGE is calling the shots in killing peer-reviewed biomedical research grants. More bombshell reporting from @maxkozlov.bsky.social in @nature.com:
NIH killed grants on orders from Elon Musk’s DOGE
Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.
www.nature.com
May 21, 2025 at 10:01 PM
Sworn testimony of NIH officials and internal emails reveal just how much DOGE is calling the shots in killing peer-reviewed biomedical research grants. More bombshell reporting from @maxkozlov.bsky.social in @nature.com:
Reposted by Jason Bini, PhD
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Another scoop from Jeff Mervis (@policyhound.bsky.social): NSF's ~1400 grant terminations have disproportionately affected PIs from groups underrepresented in science: women, racial & ethnic minorities, & those with disabilities. 1/3
www.science.org/content/arti...
www.science.org/content/arti...
Trump officials take steps toward a radically different NSF
Efforts to shrink staff, budget, and focus have alarmed members of Congress
www.science.org
May 13, 2025 at 10:09 PM
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
Reposted by Jason Bini, PhD
University leaders need to understand: they are holding INCREDIBLY good cards.
It is so rare in today's polarized era to have the support of 70+ percent of the public against the Trump admiministration on anything. Universities have that—AND winning legal arguments.
It is so rare in today's polarized era to have the support of 70+ percent of the public against the Trump admiministration on anything. Universities have that—AND winning legal arguments.
April 27, 2025 at 5:29 AM
University leaders need to understand: they are holding INCREDIBLY good cards.
It is so rare in today's polarized era to have the support of 70+ percent of the public against the Trump admiministration on anything. Universities have that—AND winning legal arguments.
It is so rare in today's polarized era to have the support of 70+ percent of the public against the Trump admiministration on anything. Universities have that—AND winning legal arguments.
Opthalmology Chic. Keeping that eye health in check!
April 24, 2025 at 6:41 PM
Opthalmology Chic. Keeping that eye health in check!
Thanks to The Grey Matter Project, Sreya and Prof Sara Schaefer for the invite and organizing! Really fun to talk to the HS students who are the next generation of Drs and researchers about neuroendocrinology.
medicine.yale.edu/neurology/ed...
medicine.yale.edu/neurology/ed...
April 23, 2025 at 12:31 AM
Thanks to The Grey Matter Project, Sreya and Prof Sara Schaefer for the invite and organizing! Really fun to talk to the HS students who are the next generation of Drs and researchers about neuroendocrinology.
medicine.yale.edu/neurology/ed...
medicine.yale.edu/neurology/ed...
Reposted by Jason Bini, PhD
My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...
Leading Nutrition Scientist Departs N.I.H., Citing Censorship (Gift Article)
Kevin Hall said his work on ultraprocessed foods has been “hobbled” under the Trump administration. Scientists have been raising such concerns for months.
www.nytimes.com
April 16, 2025 at 10:27 PM
My story about @kevinh-phd.bsky.social, nutrition and metabolism scientist at N.I.H., who felt compelled to take early retirement after experiencing censorship of his work under the new administration. www.nytimes.com/2025/04/16/w...
Reposted by Jason Bini, PhD
After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.
April 16, 2025 at 9:00 PM
After 21 years at my dream job, I’m very sad to announce my early retirement from the National Institutes of Health. My life’s work has been to scientifically study how our food environment affects what we eat, and how what we eat affects our physiology.