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y-ng.bsky.social
@y-ng.bsky.social
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pawelburkhardt.bsky.social
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience

Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E

@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
Reposted
jkohl.bsky.social
Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice.
www.nature.com/articles/s41...
Integration of hunger and hormonal state gates infant-directed aggression - Nature
Combined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups...
www.nature.com
October 22, 2025 at 3:30 PM
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thetransmitter.bsky.social
A cross-species study captured an emotional brain state characterized by lingering brain activity in higher-order areas. “It’s one of those moments where you’re getting a first glimpse at a vast and complex landscape,” says @deisseroth.bsky.social.

By @callimcflurry.bsky.social

bit.ly/3U33raF
Eye puffs prompt separable sensory, affective brain responses in mice, people
Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.
bit.ly
July 29, 2025 at 2:13 PM
Reposted
nature.com
Nature research paper: A brain-wide map of neural activity during complex behaviour

go.nature.com/4gdKcp8
A brain-wide map of neural activity during complex behaviour - Nature
The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task in mice.
go.nature.com
September 10, 2025 at 2:12 PM
Reposted
gozziale.bsky.social
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f

Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience

➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?

Check out what we found!
🧵1/n
September 10, 2025 at 3:08 PM
Reposted
thetransmitter.bsky.social
In the latest episode of @braininspired.bsky.social, @drbreaky.bsky.social and @macshine.bsky.social describe a scale-free property of brain activity conserved across diverse species, suggesting a universal principle of activity underlying cognition.

www.thetransmitter.org/brain-inspir...
Michael Breakspear and Mac Shine explain how brain processing changes across neural population scales
Breakspear and Shine find a scale-free property of brain activity that is conserved across diverse species, suggesting that a universal principle of brain activity underlies cognition.
www.thetransmitter.org
September 10, 2025 at 2:13 PM
Reposted
yulonglilab.bsky.social
1/ Excited to share a new preprint!
Our latest study uncovers how serotonin precisely controls the “time window” for fear learning, ensuring that our brains link cues (CS) & threats (US) only when it’s adaptive.
#Neuroscience #FearLearning
www.biorxiv.org/content/10.1...
Serotonin shapes the temporal window for associative fear learning
Fear learning is a critical adaptive mechanism that enables the association of an environmental cue (the conditioned stimulus, CS) with a potential threat (the unconditioned stimulus, US), even when t...
www.biorxiv.org
August 8, 2025 at 4:05 PM
Reposted
bertogliolab.bsky.social
Translational cross-species evidence of heart-related dynamics in threat learning
www.sciencedirect.com/science/arti...
Translational cross-species evidence of heart-related dynamics in threat learning
Fear engenders a vast array of autonomic responses in organisms, which are elicited by the presence of threat. Among these responses, heart rate is in…
www.sciencedirect.com
June 30, 2025 at 9:47 AM
Reposted
vincentcostaphd.bsky.social
Why do we go downstairs when we hear a scary noise at night?

New #preprint by postdoc Kati Rothenhoefer shows how novelty seeking & explore-exploit decision making in #macaques resolves curiosity about whether choices will lead to appetitive or aversive outcomes.

www.biorxiv.org/content/10.1...
Dissociable effects of curiosity and hedonic valence on reinforcement learning
Curiosity and exploration support learning and adaptive decision-making in uncertain environments. While these processes are sensitive to motivational context, it remains unclear how outcome valence s...
www.biorxiv.org
June 27, 2025 at 11:52 AM
Reposted
annaschroeder.bsky.social
Heading to EBBS? (ebbs2025.azuleon.org) Don’t miss our session (co-chaired with Suzanne Dickson) on how physiological states shape behavior. We have a fantastic lineup of speakers (Linda Engström-Ruud, @amdouglass.bsky.social, @neuronico.bsky.social, @neuroadept.bsky.social). See you in Bordeaux! 🍷
June 24, 2025 at 8:49 AM
Reposted
bertogliolab.bsky.social
GABAergic neurons of central amygdala mediate anxiety-like behavior induced by social isolation in adolescent mice
www.sciencedirect.com/science/arti...
Gabaergic neurons of central amygdala mediate anxiety-like behavior induced by social isolation in adolescent mice
Exposure to social isolation stress during critical developmental stages escalates vulnerability to psychiatric disorders and may provoke abnormal act…
www.sciencedirect.com
June 16, 2025 at 11:07 AM
Reposted
laklab.bsky.social
Our work, out at Cell, shows that the brain’s dopamine signals teach each individual a unique learning trajectory. Collaborative experiment-theory effort, led by Sam Liebana in the lab. The first experiment my lab started just shy of 6y ago & v excited to see it out: www.cell.com/cell/fulltex...
June 11, 2025 at 3:18 PM
Reposted
bertogliolab.bsky.social
A large-scale multimodal investigation of the interplay between the serotonergic system and emotion processing
www.nature.com/articles/s41...
A large-scale multimodal investigation of the interplay between the serotonergic system and emotion processing - Translational Psychiatry
Translational Psychiatry - A large-scale multimodal investigation of the interplay between the serotonergic system and emotion processing
www.nature.com
June 12, 2025 at 9:52 AM
Reposted
malu-murugan.bsky.social
A ventral hippocampal-lateral septum pathway regulates social novelty preference. Version of record - now available on @elife.bsky.social check it out doi.org/10.7554/eLif...
A ventral hippocampal-lateral septum pathway regulates social novelty preference
Projection-specific optogenetic and chemogenetic experiments reveal a hippocampal-lateral septal pathway that potentially acts via the ventral tegmental area to regulate social novelty preference beha...
doi.org
June 5, 2025 at 5:57 PM
Reposted
nadinedijkstra.bsky.social
I am beyond excited to share our new preprint ‘A neural basis for distinguishing between imagination and reality’ with Thomas von Rein, @peterkok.bsky.social and @smfleming.bsky.social! osf.io/preprints/ps... a thread 🧵
OSF
osf.io
November 15, 2024 at 8:07 AM
Reposted
gozziale.bsky.social
Two years after a fun and inspiring retreat at our institute in #Rovereto, our position paper on the future of rodent functional neuroimaging is finally out 🐭🧠👇

📄https://tinyurl.com/42spkbft

Here we outline key challenges & a roadmap to advance the field! Proud of this collaborative effort 🥳🎉
May 26, 2025 at 2:49 PM
Reposted
bertogliolab.bsky.social
Endocannabinoids disinhibit the ventral tegmental nucleus of Gudden to dorsal premammillary nucleus pathway to enhance escape behavior following learned threat experience
www.nature.com/articles/s41...
Endocannabinoids disinhibit the ventral tegmental nucleus of Gudden to dorsal premammillary nucleus pathway to enhance escape behavior following learned threat experience - Nature Communications
Neural mechanisms underlying strengthening of escape behaviors are not fully understood. Here authors show that mPFC (medial prefrontal cortex)/VTg (ventral tegmental nucleus of gudden) to cholecystok...
www.nature.com
May 27, 2025 at 11:19 AM
Reposted
bertogliolab.bsky.social
Conserved brain-wide emergence of emotional response from sensory experience in humans and mice
www.science.org/doi/10.1126/...
Conserved brain-wide emergence of emotional response from sensory experience in humans and mice
Emotional responses to sensory experience are central to the human condition in health and disease. We hypothesized that principles governing the emergence of emotion from sensation might be discovera...
www.science.org
May 29, 2025 at 7:38 PM
Reposted
benjaminkay.bsky.social
My med school textbook says stimulants like Ritalin treat hyperactivity by “stimulating” the brain’s attention and cognitive control systems. We studied children taking stimulants in the ABCD Study, and the largest differences were actually in arousal and reward networks! Check out our preprint!
May 22, 2025 at 9:33 PM
Reposted
bertogliolab.bsky.social
A midbrain circuit mechanism for noise-induced negative valence coding
www.nature.com/articles/s41...
A midbrain circuit mechanism for noise-induced negative valence coding - Nature Communications
How do sounds affect emotions? The authors reveal that noise can suppress the rewarding-dopamine system through a non-canonical auditory pathway, leading to negative emotions like aversion and anxiety...
www.nature.com
May 18, 2025 at 12:20 PM
Reposted
bertogliolab.bsky.social
Integrating reproductive states and social cues in the control of sociosexual behaviors
www.cell.com/cell/fulltex...
Integrating reproductive states and social cues in the control of sociosexual behaviors
A subset of neurons in the medial prefrontal cortex is shown to exert top-down regulation of adaptive innate reproductive behaviors by integrating social cues with estrous states to orchestrate socios...
www.cell.com
May 21, 2025 at 10:22 AM
Reposted
carolinejia.bsky.social
🧵 1\New Preprint! Social pain, the emotional pain caused by aversive experiences with other individuals, is an umbrella term that includes experiences such as social isolation, social exclusion, social rejection, and social loss and can be used as a signal to drive a need state
May 15, 2025 at 1:46 AM
Reposted
merylneuro.bsky.social
If you're attending #NeuroFrance2025 in beautiful Montpellier and you're interested in sensory processing and emotions, don't miss out our symposium tomorrow (Thursday) morning! Organized together with @mariocarta.bsky.social
@socneuro.bsky.social
May 14, 2025 at 1:14 PM
Reposted
bertogliolab.bsky.social
Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours
www.nature.com/articles/s41...
Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours - Nature
A set of neurons in the peri-locus coeruleus region controls arousal and avoidance states, providing an understanding of the neurobiological basis of arousal and exploratory behaviours.
www.nature.com
May 7, 2025 at 5:30 PM
Reposted
carlosbrody.bsky.social
we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team.

publicusaresearchbenefits.com

please share and re-share so we get more great stories in there!
Searchable database of tangible benefits that federally-funded research gave us.
A crowd-sourced site. Health and Well-being. National Security. Prosperity.
publicusaresearchbenefits.com
May 7, 2025 at 11:28 PM