Xi-Han Zhang
@xi-hanzhang.bsky.social
PhD student @YalePsychology | @HarvardChanSPH‘19 | @OUC1924 ‘17 computational biology, neuroscience, affective dynamics, mechanisms of change
Reposted by Xi-Han Zhang
🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia"
medrxiv.org/content/10.1...
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
medrxiv.org/content/10.1...
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
March 24, 2025 at 1:28 AM
🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia"
medrxiv.org/content/10.1...
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
medrxiv.org/content/10.1...
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
Reposted by Xi-Han Zhang
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
The molecular and cellular underpinnings of human brain lateralization
Hemispheric specialization is a fundamental characteristic of human brain organization, where most individuals exhibit left-hemisphere dominance for language and right-hemisphere dominance for visuosp...
doi.org
April 12, 2025 at 10:28 AM
🚨 New #preprint: The molecular and cellular underpinnings of human brain lateralization
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
🔗 doi.org/10.1101/2025...
🧠 We identify an acetylcholine-norepinephrine axis underlying functional lateralization, along with mitochondrial and cellular correlates. 🧵1/9👇
#neuroskyence
Excited to share my work revealing that functional organization of human cortex is reflected in the spatial variability of different cell types!
nature.com/articles/s41...
PDF rdcu.be/d0ZAc
nature.com/articles/s41...
PDF rdcu.be/d0ZAc
The cell-type underpinnings of the human functional cortical connectome - Nature Neuroscience
Here Zhang et al. establish multiscale relationships that link postmortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed through functional ...
nature.com
December 3, 2024 at 10:07 PM
Excited to share my work revealing that functional organization of human cortex is reflected in the spatial variability of different cell types!
nature.com/articles/s41...
PDF rdcu.be/d0ZAc
nature.com/articles/s41...
PDF rdcu.be/d0ZAc
Reposted by Xi-Han Zhang
Had a lot of fun writing this news & views article on Converging Cortical Axes with @bogglerapture.bsky.social
shorturl.at/LsB5p
shorturl.at/LsB5p
Converging cortical axes - Nature Neuroscience
The cerebral cortex shows complex organization across diverse biological scales, from regional chemical and cellular specializations to macroscale functional networks. Zhang et al. report that macrosc...
shorturl.at
November 21, 2024 at 6:13 PM
Had a lot of fun writing this news & views article on Converging Cortical Axes with @bogglerapture.bsky.social
shorturl.at/LsB5p
shorturl.at/LsB5p
Reposted by Xi-Han Zhang
Latest work led by Xihan Zhang looking at the cell-type underpinnings of the human functional cortical connectome is out now in Nature Neuro! 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The cell-type underpinnings of the human functional cortical connectome - Nature Neuroscience
Here Zhang et al. establish multiscale relationships that link postmortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed through functional ...
www.nature.com
November 21, 2024 at 6:21 PM
Latest work led by Xihan Zhang looking at the cell-type underpinnings of the human functional cortical connectome is out now in Nature Neuro! 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...