Wallace Marshall
@wallaceucsf.bsky.social
professor at UCSF, engineer turned cell biologist, wants to know how cells solve geometry problems
Lab re-union at #cellbio2025 - great to see everyone again and hear about the interesting new science they are doing!
December 14, 2025 at 3:40 AM
Lab re-union at #cellbio2025 - great to see everyone again and hear about the interesting new science they are doing!
The cell is a crowded place where organelles are packed together . In her talk this afternoon Dec 9 at CellBio2025 in the Quantitative Modeling session room 122, Mary Mirvis will show her work using soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.
December 9, 2025 at 2:43 PM
The cell is a crowded place where organelles are packed together . In her talk this afternoon Dec 9 at CellBio2025 in the Quantitative Modeling session room 122, Mary Mirvis will show her work using soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.
The cell is a crowded place where organelles are packed together . In poster B365 at CellBio2025 Monday Dec 8 in the Quantitative Modeling session room 122, Mary Mirvis uses soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.
December 7, 2025 at 10:27 PM
The cell is a crowded place where organelles are packed together . In poster B365 at CellBio2025 Monday Dec 8 in the Quantitative Modeling session room 122, Mary Mirvis uses soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.
Mitochondria form dynamic networks that can be represented as graphs. But the space of graphs is complex. In poster 376 at CellBio2025 Monday Dec 8, Raphie Mostov presents a mathematical approach to represent mitochondria far more simply.
December 7, 2025 at 10:26 PM
Mitochondria form dynamic networks that can be represented as graphs. But the space of graphs is complex. In poster 376 at CellBio2025 Monday Dec 8, Raphie Mostov presents a mathematical approach to represent mitochondria far more simply.
Stentor is a single cell with a complex cortical pattern showing anterior/posterior polarization In poster 410 at CellBio2025 Monday Dec 8, Yina Hudnall shows a role for posterior-enriched mRNA that encoding DNA binding proteins.
December 7, 2025 at 10:26 PM
Stentor is a single cell with a complex cortical pattern showing anterior/posterior polarization In poster 410 at CellBio2025 Monday Dec 8, Yina Hudnall shows a role for posterior-enriched mRNA that encoding DNA binding proteins.
Stentor is a single cell that can regenerate missing pieces, but how does it know when something is missing? In poster 406 at CellBio2025 Monday Dec 8, Connie Yan shows that conserved cell cycle machinery plays a key role in triggering cellular regeneration.
December 7, 2025 at 10:26 PM
Stentor is a single cell that can regenerate missing pieces, but how does it know when something is missing? In poster 406 at CellBio2025 Monday Dec 8, Connie Yan shows that conserved cell cycle machinery plays a key role in triggering cellular regeneration.
The giant ciliate Stentor has a macronucleus that undergoes a dramatic shape change during cellular regeneration. In poster 038 at CellBio2025 Monday Dec 8, I present work by Isabella Ibalio showing that histone modifications correlate with these dramatic nuclear shape changes.
December 7, 2025 at 10:25 PM
The giant ciliate Stentor has a macronucleus that undergoes a dramatic shape change during cellular regeneration. In poster 038 at CellBio2025 Monday Dec 8, I present work by Isabella Ibalio showing that histone modifications correlate with these dramatic nuclear shape changes.
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 163 at CellBio2025 Sunday Dec 7, I present work by Hiro Ishikawa using a synthetic biology approach to test a length-sensing model based on diffusion of kinesin in flagella
December 7, 2025 at 3:44 AM
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 163 at CellBio2025 Sunday Dec 7, I present work by Hiro Ishikawa using a synthetic biology approach to test a length-sensing model based on diffusion of kinesin in flagella
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 155 at the CellBio2025 meeting Sunday Dec 7, Ximena Garcia Arceo uses Lithium, which increases intraflagellar transport, as a tool to probe how length-altering mutants work.
December 7, 2025 at 3:43 AM
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 155 at the CellBio2025 meeting Sunday Dec 7, Ximena Garcia Arceo uses Lithium, which increases intraflagellar transport, as a tool to probe how length-altering mutants work.
The low Reynolds number of cytoplasmic flow which makes mixing hard. In poster 359 at the CellBio2025 meeting Sunday Dec 7, Ulises Diaz shows how giant cells leverage reversible actin gel assembly to drive rapid mixing of cytoplasm, faster even than "chaotic mixing" schemes.
December 7, 2025 at 3:43 AM
The low Reynolds number of cytoplasmic flow which makes mixing hard. In poster 359 at the CellBio2025 meeting Sunday Dec 7, Ulises Diaz shows how giant cells leverage reversible actin gel assembly to drive rapid mixing of cytoplasm, faster even than "chaotic mixing" schemes.
Cells can hunt prey, solve mazes, and learn from past experience. Does this mean they can think, at some level? Find out more at our upcoming session on "Cell Behavior and Cognition" at the ASCB/EMBO #cellbio2025 meeting, Saturday 1-3 pm rm 115.
December 5, 2025 at 2:36 PM
Cells can hunt prey, solve mazes, and learn from past experience. Does this mean they can think, at some level? Find out more at our upcoming session on "Cell Behavior and Cognition" at the ASCB/EMBO #cellbio2025 meeting, Saturday 1-3 pm rm 115.
Reposted by Wallace Marshall
Reach out and touch somebody’s future organelle?
Make this place a better world, if you can.
Make this place a better world, if you can.
An Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms
December 5, 2025 at 2:25 AM
Reach out and touch somebody’s future organelle?
Make this place a better world, if you can.
Make this place a better world, if you can.
My first ever time doing a podcast - part of “that’s absurd, please elaborate”, recorded live at the Bay Area Science Festival.
thatsabsurdshow.com
Discussing two topics- does saturable transport mean you can eat as much as you want? and what would happen if tardigrades were a lot bigger?
thatsabsurdshow.com
Discussing two topics- does saturable transport mean you can eat as much as you want? and what would happen if tardigrades were a lot bigger?
That's Absurd Please Elaborate
thatsabsurdshow.com
December 5, 2025 at 12:25 AM
My first ever time doing a podcast - part of “that’s absurd, please elaborate”, recorded live at the Bay Area Science Festival.
thatsabsurdshow.com
Discussing two topics- does saturable transport mean you can eat as much as you want? and what would happen if tardigrades were a lot bigger?
thatsabsurdshow.com
Discussing two topics- does saturable transport mean you can eat as much as you want? and what would happen if tardigrades were a lot bigger?
Reposted by Wallace Marshall
Check out that spindle 🤩🔥
At 63C, most eukaryotic cells would be busy exploding noisily, forget even trying to divide.
The microbial universe never ceases to astound 😍
Thanks for letting us be a tiny part of this! #ExpandThemAll
At 63C, most eukaryotic cells would be busy exploding noisily, forget even trying to divide.
The microbial universe never ceases to astound 😍
Thanks for letting us be a tiny part of this! #ExpandThemAll
While 𝘝. 𝘷𝘦𝘳𝘮𝘪𝘧𝘰𝘳𝘮𝘪𝘴 max temp is around 45°C, we found 𝘐. 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴 grows up to 63°C with optimal growth at 55-57°C🥵. We showed cellular replication via Ultrastructure Expansion Microscopy at 63°C. The previous limit for euks is 60°C!
November 25, 2025 at 8:30 PM
Check out that spindle 🤩🔥
At 63C, most eukaryotic cells would be busy exploding noisily, forget even trying to divide.
The microbial universe never ceases to astound 😍
Thanks for letting us be a tiny part of this! #ExpandThemAll
At 63C, most eukaryotic cells would be busy exploding noisily, forget even trying to divide.
The microbial universe never ceases to astound 😍
Thanks for letting us be a tiny part of this! #ExpandThemAll
Reposted by Wallace Marshall
“You’re a stupid person” — Trump lashes out at a reporter who presses him on the fact that the suspected DC shooter was actually thoroughly vetted before he was let in the US from Afghanistan
November 28, 2025 at 12:24 AM
“You’re a stupid person” — Trump lashes out at a reporter who presses him on the fact that the suspected DC shooter was actually thoroughly vetted before he was let in the US from Afghanistan
Reposted by Wallace Marshall
Some cells are just in it for the drama!
The bottom 5 microns of cells videoed through a microscope by @EmmaKoory. The middle cell rounds up (for fun?) and subsequently rounds up to divide. We missed so much of the action by just sampling the bottom. @CellBiology
The bottom 5 microns of cells videoed through a microscope by @EmmaKoory. The middle cell rounds up (for fun?) and subsequently rounds up to divide. We missed so much of the action by just sampling the bottom. @CellBiology
November 24, 2025 at 9:19 PM
Some cells are just in it for the drama!
The bottom 5 microns of cells videoed through a microscope by @EmmaKoory. The middle cell rounds up (for fun?) and subsequently rounds up to divide. We missed so much of the action by just sampling the bottom. @CellBiology
The bottom 5 microns of cells videoed through a microscope by @EmmaKoory. The middle cell rounds up (for fun?) and subsequently rounds up to divide. We missed so much of the action by just sampling the bottom. @CellBiology
Reposted by Wallace Marshall
Reposted by Wallace Marshall
SEN. KELLY : “They informed me of this in a tweet because this is not about the law. This is about the media cycle, and intimidation… We basically repeated the uniform code of military justice, and they're saying that's in violation of it. It's absurd. Comical.”
November 25, 2025 at 3:15 AM
SEN. KELLY : “They informed me of this in a tweet because this is not about the law. This is about the media cycle, and intimidation… We basically repeated the uniform code of military justice, and they're saying that's in violation of it. It's absurd. Comical.”
Reposted by Wallace Marshall
Weird word of the day: "kleptosquamy." The testate amoeba Awerintzewia cyclostoma steals scales from other amoeboid organisms to build its own shell. This one has robbed Quadrulella, Netzelia, various euglyphids, and even an Acanthocystis. Kleptosquamy! #amoebae #ProtistsOnSky #biology #nature
November 21, 2025 at 12:00 AM
Weird word of the day: "kleptosquamy." The testate amoeba Awerintzewia cyclostoma steals scales from other amoeboid organisms to build its own shell. This one has robbed Quadrulella, Netzelia, various euglyphids, and even an Acanthocystis. Kleptosquamy! #amoebae #ProtistsOnSky #biology #nature
Reposted by Wallace Marshall
now i've seen everything... 😱
don't care what anybody says but #protists are cognitive
don't care what anybody says but #protists are cognitive
Cellular structure self-organizes through an interplay between internal mechanisms and external cues. The single-celled suctorian P. collini builds a trap structure to capture large prey using microtubule feeding tentacles, creating feedback between cell morphology and prey availability.
November 19, 2025 at 1:46 PM
now i've seen everything... 😱
don't care what anybody says but #protists are cognitive
don't care what anybody says but #protists are cognitive
Reposted by Wallace Marshall
Students attending the departmental seminar just for the refreshments
November 11, 2025 at 5:29 PM
Students attending the departmental seminar just for the refreshments
Reposted by Wallace Marshall
Good morning to all those people who wasted the last decade saying, "there's no point tackling climate change in the UK, because China."
www.theguardian.com/world/2025/n...
www.theguardian.com/world/2025/n...
China’s CO2 emissions have been flat or falling for past 18 months, analysis finds
World’s biggest polluter on track to hit peak emissions target early but miss goal for cutting carbon intensity
www.theguardian.com
November 11, 2025 at 7:08 AM
Good morning to all those people who wasted the last decade saying, "there's no point tackling climate change in the UK, because China."
www.theguardian.com/world/2025/n...
www.theguardian.com/world/2025/n...
Wound healing is a hallmark feature of all life, including single cells. In a new preprint, Ambika Nadkarni @biochembika.bsky.social investigates a new dimension in cellular wound healing: how cells recover AFTER the wound has been closed
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 10, 2025 at 5:47 PM
Wound healing is a hallmark feature of all life, including single cells. In a new preprint, Ambika Nadkarni @biochembika.bsky.social investigates a new dimension in cellular wound healing: how cells recover AFTER the wound has been closed
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Wallace Marshall
Garfield is the guy, actually he's called Garfield's monster
November 8, 2025 at 4:03 AM
Garfield is the guy, actually he's called Garfield's monster
Reposted by Wallace Marshall
Same - solutions?
Several of our students have run into an issue where their "official transcript" is password protected/encrypted which prevents them from being able to upload. If they un-encrypt the document, it removes the "official transcript" watermark.
Complete Catch-22 here, does anyone have a work around?
Complete Catch-22 here, does anyone have a work around?
Warning. ⚠️ If you are writing an NSF GRFP, new this year, you need official transcripts to apply. Beware. They will not review applications without official transcripts. ‼️
November 7, 2025 at 2:13 AM
Same - solutions?