Victor DeFilippis
vrdef.bsky.social
Victor DeFilippis
@vrdef.bsky.social
Innate immunologist, virologist, #cGAS, #STING, #Vaccines. Harpo Marxist.
Reposted by Victor DeFilippis
“In 1900, 30 percent of all deaths in the United States occurred among children younger than 5, mostly because of preventable infectious diseases. By the end of the century, that number was just 1.4 percent.” #VaccinesWork #VaccinesSaveLives #ACIP
June 11, 2025 at 3:48 AM
www.whitehouse.gov/presidential...
Jeffrey Taubenberger is the new head of NIAID and is literally famous for research that violated this executive order.
Improving the Safety and Security of Biological Research
By the authority vested in me as President by the Constitution and the laws of the United States of America, it is hereby ordered: Section 1.  Purpose.
www.whitehouse.gov
May 7, 2025 at 9:09 PM
Reposted by Victor DeFilippis
Are you a professor or assistant professor level researcher in the US or elsewhere outside of Finland? Looking for new opportunities in an inspiring and well-connected research environment? Finland might be just the place for you.

Reach out to Finnish universities to explore what’s possible.
Finland invests in research excellence – new funding call by Research Council of Finland to support recruitment of international talents
The Research Council of Finland (RCF) has launched a funding call to improve universities’ ability to recruit international experts to Finland. In line with the RCF’s strategy, the call wi...
www.aka.fi
April 16, 2025 at 12:23 PM
I have read these e-mail notifications for many years. Horrifying does not even come close to describing the effect of this latest one.
April 12, 2025 at 2:29 PM
Reposted by Victor DeFilippis
So long, NIH. The place I grew up in and discovered my passion for science communication.

I found a true calling to help take innovative genomics research and make it accessible, interesting and fun for wider audiences.

I'm so devastated that my whole team got laid off today.
April 1, 2025 at 11:01 PM
Reposted by Victor DeFilippis
Studies terminated at NIH:
-On reducing asthma from mold
-On prenatal risks & screening
-On statins influence on dementia
-On the safety/risk of gender-affirming care
-On how Covid vax outcomes & disparities
-On improving HIV care
-Training programs for the next generation of scientists
taggs.hhs.gov
March 19, 2025 at 1:44 PM
Reposted by Victor DeFilippis
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
Reposted by Victor DeFilippis
I have worked with many untenured staff scientists & PIs at NIH. They are incredible colleagues who chose science in public service over more lucrative careers. Devaluing their commitment & professionalism is among the most cruel aspects of the DOGE purge

www.science.org/content/arti...
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
www.science.org
February 28, 2025 at 11:49 AM
Reposted by Victor DeFilippis
Come join us! No excuses!!!
Only 1 week until the Stand Up For Science rally at the OR capitol! We'll be hearing from Rep. Andrea Salinas and at least 4 renowned scientists. Rally with me to defend science from censorship and cuts! Let's make this big! #sciencenotsilence #standupforscience2025 @standupforscience.bsky.social
February 28, 2025 at 3:53 AM
Reposted by Victor DeFilippis
As of today, at least 73 study sections have not met. If they review 50 applications, plus 30 triaged, 10% funding rate = 8 grants per SS.

That's 584 fundable grants on hold. Probably 5000 researchers affected in those teams composed of our best and brightest.

SABOTAGE.
Wondering if your study section cancelled? I update this sheet daily. As of today, 56/124 study sections that should have met since Jan 2, 2025 have "not met as scheduled." docs.google.com/spreadsheets...
2025 Study section tracking
docs.google.com
February 26, 2025 at 6:04 PM
Reposted by Victor DeFilippis
OpEd by @scripps.edu Pres. Pete Shultz: "the consequences would extend beyond Scripps Research, threatening the broader San Diego life sciences ecosystem, which contributes over $27 billion to the regional economy and supports tens of thousands of jobs."
www.sandiegouniontribune.com/2025/02/25/o...
Opinion: Science funding cuts are based on flawed logic. Here’s the truth.
Earlier this month, the National Institutes of Health issued supplemental guidance indicating it would immediately impose a 15% cap on indirect costs for research grants, an unprecedented and abrup…
www.sandiegouniontribune.com
February 25, 2025 at 7:57 PM
Reposted by Victor DeFilippis
I created a brief spreadsheet of reductions I've heard of so far. Any additions you know of (especially if you have the links/receipts) would be great: docs.google.com/spreadsheets...
Graduate Reductions Across Biomedical Sciences (2025)
docs.google.com
February 22, 2025 at 1:23 PM
Reposted by Victor DeFilippis
“Many grad programs are pausing and reducing admissions in response to NIH funding pauses and pending EO’s on indirect cost reductions. These workforce reductions have the potential to imminently and irreversibly harm research labs & grad programs”
I created a brief spreadsheet of reductions I've heard of so far. Any additions you know of (especially if you have the links/receipts) would be great: docs.google.com/spreadsheets...
Graduate Reductions Across Biomedical Sciences (2025)
docs.google.com
February 22, 2025 at 1:54 PM
Reposted by Victor DeFilippis
Excited to announce our next speaker Dr William de Souza who will be presenting work on virus transmission dynamics of #emerging #arboviruses NEXT THURSDAY.
Will be great to get some perspective from an up-and-coming investigator. PLEASE help with a repost for this community driven seminar series.
February 12, 2025 at 1:38 PM
Reposted by Victor DeFilippis
www.nytimes.com/2025/01/30/h...

Yet another amazing story of many strands of basic investigation emerging out of our science ecosystem, yielding a new therapeutic class of non opiate analgesics.
FDA Approves Journavx Drug to Treat Pain Without Addiction Risk
The drug, Journavx by Vertex Pharmaceuticals, blocks pain signals to the brain, making it nonaddictive.
www.nytimes.com
February 1, 2025 at 2:09 PM
Reposted by Victor DeFilippis
I participated in a faculty panel a few weeks ago in which senior (ahem) faculty gave advice on careers in academia by pretending luck had very little to do with our success. One piece of advice riled me up, in which it was argued that a reason for their success was their ability to say no. 1/
December 9, 2024 at 3:16 AM
Reposted by Victor DeFilippis
The generation of disinformation is easy. You make a graph, type something, and you are done.

Showing how wrong it is takes more time. This is an easy example. The graph is made up, but for some, it will not be clear why this is wrong and is dangerous disinformation.
1/7
December 29, 2024 at 12:16 PM
Reposted by Victor DeFilippis
40 years ago all of Genbank was published in print form by NAR. The same format today would require over 4 light seconds of shelf space. To a year of progress in 2025.
December 29, 2024 at 9:50 AM
Reposted by Victor DeFilippis
NIH funded research made important breakthroughs in 2024. Another reminder of why sustained funding for science and research is so vital. Of note 3 NIH funded scientists were recognized with the nobel prize. 5 top health related research highlights here
👇🏾
www.nih.gov/news-events/...
2024 NIH Research Highlights - Promising Medical Findings
NIH findings with potential for enhancing human health include insights into the mechanisms of ME/CFS, a skin test to detect Parkinson’s disease and related disorders, and a promising target for catar...
www.nih.gov
December 26, 2024 at 10:59 PM
Reposted by Victor DeFilippis
This week in #Science #Immunology: Glen Barber & colleagues report that #cGas#STING signaling in phagocytosed DNA-damaged cells facilitates #APC activation via formation of STING-inducible endosomal vesicles (SIEVES) containing immune-activating proteins and cytosolic DNA!
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells
Both cytosolic DNA species and innate immune STING signaling are required for stressed cells to activate phagocytes.
www.science.org
December 20, 2024 at 9:11 PM