Vicente Pérez-García
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vpglab.bsky.social
Vicente Pérez-García
@vpglab.bsky.social
Group Leader @cbm-csic-uam.bsky.social l NGF @loke-ctr.bsky.social The VPGlab is interested in placenta development, pregnancy disorders and cancer l Trophoblast stem cells, placenta, CRISPR, Sella i tal.
Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction | New England Journal of Medicine www.nejm.org/doi/full/10....
Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction | NEJM
The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction (LVEF) is unclear. We conducted a meta-analysis at the individual-patient le...
www.nejm.org
November 9, 2025 at 9:37 PM
Reposted by Vicente Pérez-García
Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇

- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
October 2, 2025 at 8:15 AM
Reposted by Vicente Pérez-García
2 weeks left to apply! Fully-funded 4-year PhD studentships for home or overseas students, applications open till 4 November. 🔗 Please like and share to spread the word! www.trophoblast.cam.ac.uk/phd-students...

Take a look at projects for 2025/26 www.trophoblast.cam.ac.uk/opportunitie...
October 20, 2025 at 3:43 PM
Reposted by Vicente Pérez-García
Very happy to share I've written a review on placental vascular formation in mice and humans, now published in @dev-journal.bsky.social.

journals.biologists.com/dev/article/...

@idrm.ox.ac.uk Funded by the @thebhf.bsky.social
Feto-placental blood vessel development
Summary: This Review contains an overview of placental vascular development and pathologies in mice and humans and highlights key remaining questions in the field.
journals.biologists.com
June 2, 2025 at 10:24 AM
Reposted by Vicente Pérez-García
✳️ Join us for this week's interesting #CiMUSSeminar with guest speaker @vpglab.bsky.social from @cbm-csic-uam.bsky.social.

Dr. Vicente Pérez explores novel therapies for pregnancy disorders & cancer

Hosted by PI @mobilegenomes.bsky.social mes.bsky.social

#RedeCIGUS #FondosEuropeos @usc.gal
April 2, 2025 at 9:01 AM
Reposted by Vicente Pérez-García
Using #CRISPR/Cas9 to genetically modify cells to produce extracellular matrices with altered compositions.
elifesciences.org/reviewed-pre...
March 23, 2025 at 9:01 PM
Reposted by Vicente Pérez-García
Check out these feather buds on the chicken embryo's wing! Our latest study @plosbiology.org reveals that temporary inhibition of sonic hedgehog signalling transforms feathers into simple, protofeather-like structures—similar to those of their dinosaur ancestors🔬🦖🧪

journals.plos.org/plosbiology/...
March 21, 2025 at 10:06 AM
Reposted by Vicente Pérez-García
A study in Nature Communications shows that Zika virus NS1 induces tunneling nanotubes in placental cells, which facilitate viral spread and transport of mitochondria in placental cells. The findings could be used to develop therapeutic strategies targeted against this transmission mode. 🧪
Zika virus NS1 drives tunneling nanotube formation for mitochondrial transfer and stealth transmission in trophoblasts - Nature Communications
Michita et al. show that Zika virus (ZIKV) NS1 induces tunneling nanotubes (TNTs) in placental cells, which facilitate viral spread and transport of mitochondria in placental cells. Infection with a NS1 mutant ZIKV not inducing TNTs results in a higher interferon response than wild-type ZIKV infection.
go.nature.com
March 1, 2025 at 2:32 PM
Reposted by Vicente Pérez-García
Our new paper linking Tregs, uNK cells & uterine vasculature “Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice” super effort from Alison Care, Shanna Hosking, Lachlan Moldenhauer and all the team! insight.jci.org/articles/vie...
JCI Insight - Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice
insight.jci.org
January 24, 2025 at 11:24 PM
Reposted by Vicente Pérez-García
Applications are open for our Caregiver Travel Grant 2025! Apply now for a chance to receive flexible funding to cover caregiving expenses while attending an in-person scientific conference! Apply: www.mothersinscience.com/caregiver-tr... 📅 Deadline: March 31, 2025 #WomenInSTEM #STEMM #AcademicMama
January 10, 2025 at 10:13 AM
Reposted by Vicente Pérez-García
Excited to share our most recent work in Cell Stem Cell, led by @georgiaplea.bsky.social, characterising determinants of DNA methylation patterning in human trophoblast stem cells! A great collaboration with @vpglab.bsky.social.
tinyurl.com/93mchcd2

@loke-ctr.bsky.social @cam-repro.bsky.social
Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome
The placental DNA methylation landscape is unique, with widespread partially methylated domains (PMDs). The placental “methylome” is conserved across …
tinyurl.com
January 8, 2025 at 4:21 PM