UGSF-Glycobiology
LightNews LightNews
banner
ugsf-lille.bsky.social
UGSF-Glycobiology
@ugsf-lille.bsky.social
110 followers 140 following 18 posts
Official account of the Institute for Functional and Structural Glycobiology. Doing glycosciences in Lille, France, since 1958.
🔗 https://ugsf.univ-lille.fr/en/
Posts Replies Media Videos
ugsf-lille.bsky.social
🧬 New paper out from our Computational Molecular Systems Biology team at @UGSF-lille !
Proud to have contributed to the CAPRI 8 challenge

🔗 Read it here: onlinelibrary.wiley.com/doi/10.1002/...

#CAPRI8 #AlphaFold #ProteinStructure #StructuralBiology #AIinBiology #Bioinformatics #UGSF
Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation
We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID-related Rounds), which have witnessed the transition to AI-driven predict...
onlinelibrary.wiley.com
October 6, 2025 at 11:47 AM
Reposted by UGSF-Glycobiology
pasteurlille.bsky.social
🔬 Les équipes lilloises d’Isabelle Landrieu et Luc Buée ont montré l’intérêt de nanobodies™ qui lient la protéine tau et empêchent sa pénétration dans les cellules cérébrales, bloquant ainsi sa propagation.
🚀Une avancée pour des thérapies ciblées contre Alzheimer 👉 pasteur-lille.fr/2025/04/30/p...
May 26, 2025 at 1:21 PM
Reposted by UGSF-Glycobiology
thencfg.bsky.social
📢 Our latest work describing a new versatile click chemistry glycan linker which enabled us to create glycan derivatives for use in microarrays, Luminex (bead based arrays) and ELISA assays.

Check it out in @acs.org ACS Central Science doi.org/10.1021/acsc...

#glycotime #clickchemistry #luminex
Novel Click Coupling Chemistry to Explore Glycan Recognition
Specific recognition of glycans by proteins is important in many biological processes and immune responses. Here we present a general approach for derivatizing free glycans with a novel linker MTZ (3-...
doi.org
April 24, 2025 at 5:52 PM
Reposted by UGSF-Glycobiology
cnrs-hautsdefrance.bsky.social
Vous avez toujours rêvé de visiter un laboratoire de biologie ? 🧐

Découvrez l' @ugsf-lille.bsky.social en compagnie de @ylizur.bsky.social, Corentin Spriet et les équipes de l'unité dans ce replay du live du 20 mars !
youtu.be/SqTEuVX8HF0

@cnrsbiologie.bsky.social @univlille.bsky.social
Ô Labo ! 🧪Au cœur du vivant avec l'équipe de l'UGSF !
YouTube video by Ylizur - Journaliste Scientifique
youtu.be
April 23, 2025 at 8:21 AM
Reposted by UGSF-Glycobiology
cnrsbiologie.bsky.social
👋 @lkremer1.bsky.social @cnrs-hautsdefrance.bsky.social @inserm.fr @univlille.bsky.social @ugsf-lille.bsky.social @umontpellier.bsky.social

👉 Lire l'article dans @naturecomms.bsky.social

buff.ly/Z5szsdt
A glycosylated lipooctapeptide promotes uptake and growth of Mycobacterium abscessus in the host - Nature Communications
Leclercq et al report the structure of a glycosylated lipooctapeptide (GL8P) produced by Mycobacterium abscessus. GL8P is shown to induce a strong humoral response in infected patients and to…
www.nature.com
April 15, 2025 at 12:02 PM
Reposted by UGSF-Glycobiology
glyconet.bsky.social
Thank you to the Mizutani Foundation for Glycoscience for partnering with #Glyco27, taking place May 25-30, 2025 in Edmonton!

Join us to explore the latest in #glycoscience and #biotechnology: www.glyco27.org/en/begin

Want to partner? glyco27.org/en/sponsor

@glycotime.bsky.social
April 9, 2025 at 4:03 PM
ugsf-lille.bsky.social
New study in Nature Communications: We identified a novel surface glycoconjugate essential for Mycobacterium abscessus virulence—a potential diagnostic target. Huge thanks to the amazing collab btw @lkremer1.bsky.social, JL Herrmann & @yguerardel.bsky.social
@cnrsbiologie.bsky.social
April 9, 2025 at 8:10 AM
ugsf-lille.bsky.social
🚴‍♂️ Lille, Glycoscience capital of France ! 🚴‍♂️

95km cycling around Lille by our colleague @yguerardel.bsky.social today, following glucose's path. Rough pavements between C1 and C2 & headwinds between C5 and hemiacetal oxygen.

Next goals: add the C6 and train hard for sialic acid (9 carbons😓)!
April 5, 2025 at 5:17 PM
ugsf-lille.bsky.social
🚀 Ready to boost your glycobiology skills?

Join our INSERM-backed workshops, “Glycobiology: the sweet side of life in heath and disease”, led by top experts!

📍Theory: Bordeaux - Oct 15–17, 2025)

📍Practice: Lille/Nancy Nov 12–14, 2025

Register now until June 27 : tinyurl.com/2mzf5dy3
March 26, 2025 at 4:05 PM
Reposted by UGSF-Glycobiology
nickescott.bsky.social
for my first bluesky post I'm happy to share a fun project from the lab we have been working on for a few years exploring the essentiality of genes involved in o-linked protein glycan biosynthesis in Burkholderia! www.biorxiv.org/content/10.1...
The Late-Stage Steps of Burkholderia cenocepacia Protein O-Linked Glycan Biosynthesis Are Conditionally Essential.
Periplasmic O-linked protein glycosylation is a highly conserved process observed across the Burkholderia genus. Within Burkholderia , protein glycosylation requires the five gene cluster known as the...
www.biorxiv.org
November 23, 2024 at 7:37 AM
ugsf-lille.bsky.social
🌾 Our new research shows that vibrational spectroscopy (FT-IR) effectively monitors flax dew retting, crucial for high-quality fibers. Using multivariate analysis, we identified key spectral changes, revealing more candidates than traditional methods. tinyurl.com/3sjdnb29

@cnrsbiologie.bsky.social
March 24, 2025 at 5:35 PM
Reposted by UGSF-Glycobiology
ugsf-lille.bsky.social
If, like us, you love getting lost in the Tree of Life, check out the updated version of 🌳🔍 lifemap.cnrs.fr — developed by @damdevienne.bsky.social at @cnrsbiologie.bsky.social. It's more amazing than ever! 🌟 #TreeOfLife #Science #Biodiversity
March 13, 2025 at 10:51 AM
ugsf-lille.bsky.social
If, like us, you love getting lost in the Tree of Life, check out the updated version of 🌳🔍 lifemap.cnrs.fr — developed by @damdevienne.bsky.social at @cnrsbiologie.bsky.social. It's more amazing than ever! 🌟 #TreeOfLife #Science #Biodiversity
March 13, 2025 at 10:51 AM
Reposted by UGSF-Glycobiology
cnrs.fr
#CNRSnews 📰 As the world celebrates International Women’s Day, CNRS News looks at the scientific achievements of Hollywood actress Hedy Lamarr and the little consideration her findings were given, like those of other female scientists throughout history
When beauty overshadows scientific genius
news.cnrs.fr
March 12, 2025 at 5:22 PM
ugsf-lille.bsky.social
New paper out! 🚀 Our latest publication from the ANR project DYPROSOME is now published in *Scientific Reports*. Check it out: www.nature.com/articles/s41...
Project link: anr.fr/Project-ANR-...
The ‘very moment’ when UDG recognizes a flipped-out uracil base in dsDNA - Scientific Reports
Scientific Reports - The ‘very moment’ when UDG recognizes a flipped-out uracil base in dsDNA
www.nature.com
March 12, 2025 at 7:44 AM
Reposted by UGSF-Glycobiology
ugsf-lille.bsky.social
How are calcium and glycosylation linked? Dr. Foulquier’s team reveals SLC10A7’s role in balancing calcium in the ER & Golgi, essential for proper glycosylation. SLC10A7 regulates COSMC/C1GALT1, impacting mucin-type glycosylation. More coming soon!
Full story here link.springer.com/article/10.1...
March 11, 2025 at 3:09 PM
ugsf-lille.bsky.social
How are calcium and glycosylation linked? Dr. Foulquier’s team reveals SLC10A7’s role in balancing calcium in the ER & Golgi, essential for proper glycosylation. SLC10A7 regulates COSMC/C1GALT1, impacting mucin-type glycosylation. More coming soon!
Full story here link.springer.com/article/10.1...
March 11, 2025 at 3:09 PM
ugsf-lille.bsky.social
UGSF is excited to announce our paper in RSC Chemical Biology on developing multimodal molecular probes for glycosylation bioimaging. This work, with LASIRe (Lille) & ESRF (Grenoble), is featured on the March 2025 cover! Read more: doi.org/10.1039/D4CB...
March 11, 2025 at 9:49 AM
ugsf-lille.bsky.social
SUGARS, again
phys.org/news/2025-02...
Research taps into sugary secrets of plant nectar to bite back against mosquito-spread disease
In a study published in Scientific Reports, researchers from the Royal Botanic Gardens, Kew, working with partners in Africa and the UK, present a novel plant-host identification method that could hel...
phys.org
March 2, 2025 at 1:31 PM
Reposted by UGSF-Glycobiology
ben-ezraty.bsky.social
Poste d’ingénieur(e) de recherche CNRS – 18 mois – Marseille
Rejoignez notre équipe sur un projet de prématuration du CNRS ! Nous recherchons un(e) ingénieur(e) de recherche spécialisé(e) en microbiologie, biologie moléculaire et en microscopie.
🫵 🔬👨‍🔬👩‍🔬

emploi.cnrs.fr/Offres/CDD/U...
February 27, 2025 at 4:20 PM
Reposted by UGSF-Glycobiology
cnrsbiologie.bsky.social
🐠✨ Comment le poisson-clown échappe-t-il aux toxines de son anémone protectrice ? Grâce à… son mucus ! 🧐

Un nouvel épisode passionnant du podcast Avec Sciences sur @franceculture.fr explore cette incroyable adaptation. 🌊🔬

🎧 À écouter ici 👉 buff.ly/3XoPQwj
February 28, 2025 at 8:27 AM
ugsf-lille.bsky.social
New MassiveFold release 1.4.0: it is now possible to model ligands and glycosylations with AlphaFold3!

MassiveFold is a software for molecular structure prediction with AlphaFold2, ColabFold and AlphaFold3.

More details : github.com/GBLille/Mass...

Publication : www.nature.com/articles/s43...
February 28, 2025 at 8:14 AM
Reposted by UGSF-Glycobiology
cnrsbiologie.bsky.social
#ResultatScientifique 🔎| Découvrez la dernière publication de Sébastien Léon et de ses collaborateurs ⤵️

🤝 @cnrs-idf-villejuif.bsky.social @upcite.bsky.social @ijmonod.bsky.social
📕 Biology of the Cell | https://buff.ly/41pMQ5m
February 22, 2025 at 8:00 AM
Reposted by UGSF-Glycobiology
cashwood.proteaglyco.com
A POGase is a huge advance in the glycomics field, which has typically relied on chemical or incomplete enzymatic releases (no Sia).
Expect a lot of multi-omic studies enabled by this (N-glycomics, O-glycomics, and proteomics) since the peptide backbone is left intact.
www.nature.com/articles/s41...
February 25, 2025 at 11:49 PM
ugsf-lille.bsky.social
Happy to share a new publication from our UGSF collaborator David Dauvillée @chlamyd0.bsky.social
February 26, 2025 at 12:42 PM