Stephen Vaughan
@tropicalmed.bsky.social
Tropical Infection and HIV Specialist, Fellowship Program Director, Researcher
Reposted by Stephen Vaughan
🧵 Essential ID Papers for 2025: A Clinician’s Guide
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
December 22, 2025 at 3:22 PM
🧵 Essential ID Papers for 2025: A Clinician’s Guide
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Each year brings a flood of amazing ID literature.
Here are candidates for some of the most important ID papers of 2025, spanning guidelines, trials, antimicrobials, and vaccines.
👇
Reposted by Stephen Vaughan
Single dose Butantan-DV is a live, attenuated vaccine for Dengue.
In late-stage human trials, the vaccine showed 74.7 per cent overall efficacy, 91.6 per cent efficacy against more severe forms of the disease and 100% against hospitalizations. #IDSky
www.news-medical.net/news/2025120...
In late-stage human trials, the vaccine showed 74.7 per cent overall efficacy, 91.6 per cent efficacy against more severe forms of the disease and 100% against hospitalizations. #IDSky
www.news-medical.net/news/2025120...
Single-dose dengue vaccine will benefit populations in hard-to-reach regions
A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially benefit populations in hard-to-reach regions of the country such as the Amazon,...
www.news-medical.net
December 4, 2025 at 2:17 PM
Single dose Butantan-DV is a live, attenuated vaccine for Dengue.
In late-stage human trials, the vaccine showed 74.7 per cent overall efficacy, 91.6 per cent efficacy against more severe forms of the disease and 100% against hospitalizations. #IDSky
www.news-medical.net/news/2025120...
In late-stage human trials, the vaccine showed 74.7 per cent overall efficacy, 91.6 per cent efficacy against more severe forms of the disease and 100% against hospitalizations. #IDSky
www.news-medical.net/news/2025120...
Reposted by Stephen Vaughan
France reports MERS in 2 travelers who had been to Middle East
No secondary transmission chains have been identified in France.
www.cidrap.umn.edu/f...
Photo: NIAID
No secondary transmission chains have been identified in France.
www.cidrap.umn.edu/f...
Photo: NIAID
December 4, 2025 at 9:00 PM
France reports MERS in 2 travelers who had been to Middle East
No secondary transmission chains have been identified in France.
www.cidrap.umn.edu/f...
Photo: NIAID
No secondary transmission chains have been identified in France.
www.cidrap.umn.edu/f...
Photo: NIAID
😳 Tick Borne Encephalitis 🧠 and European Lyme in a returned traveler from Czechia 🇨🇿
Ixodes ricinus (Tick) - you bad bug!
beaconbio.org/en/report/?r...
Ixodes ricinus (Tick) - you bad bug!
beaconbio.org/en/report/?r...
BEACON
Track biological threats, share vital information, and collaborate on solutions for community protection and preparedness.
beaconbio.org
December 4, 2025 at 8:20 PM
😳 Tick Borne Encephalitis 🧠 and European Lyme in a returned traveler from Czechia 🇨🇿
Ixodes ricinus (Tick) - you bad bug!
beaconbio.org/en/report/?r...
Ixodes ricinus (Tick) - you bad bug!
beaconbio.org/en/report/?r...
🪱Where parasites hide
🥗 Foods, water, and environments to avoid
🪰 How to stay safe abroad
Travel Unravelled Podcast!
YouTube: m.youtube.com/watch?v=ZMyL...
Dr. Aisha Khatib, ISTM president Dr. Anne McCarthy, Dr. Henry Wu with tropical medicine experts Dr. Carlos Seas and Dr. Stephen Vaughan.
🥗 Foods, water, and environments to avoid
🪰 How to stay safe abroad
Travel Unravelled Podcast!
YouTube: m.youtube.com/watch?v=ZMyL...
Dr. Aisha Khatib, ISTM president Dr. Anne McCarthy, Dr. Henry Wu with tropical medicine experts Dr. Carlos Seas and Dr. Stephen Vaughan.
Unwanted Souvenirs: Top Five Parasites in Travellers
YouTube video by The International Society of Travel Medicine
m.youtube.com
December 3, 2025 at 10:20 PM
🪱Where parasites hide
🥗 Foods, water, and environments to avoid
🪰 How to stay safe abroad
Travel Unravelled Podcast!
YouTube: m.youtube.com/watch?v=ZMyL...
Dr. Aisha Khatib, ISTM president Dr. Anne McCarthy, Dr. Henry Wu with tropical medicine experts Dr. Carlos Seas and Dr. Stephen Vaughan.
🥗 Foods, water, and environments to avoid
🪰 How to stay safe abroad
Travel Unravelled Podcast!
YouTube: m.youtube.com/watch?v=ZMyL...
Dr. Aisha Khatib, ISTM president Dr. Anne McCarthy, Dr. Henry Wu with tropical medicine experts Dr. Carlos Seas and Dr. Stephen Vaughan.
Reposted by Stephen Vaughan
Fascinating CID Brief Report #HIVsky #IDsky
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice
Abstract. The potential for hepatitis B reactivation must be considered when switching people with HIV and prior hepatitis B exposure away from tenofovir-c
academic.oup.com
November 23, 2025 at 1:40 AM
Fascinating CID Brief Report #HIVsky #IDsky
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
« Hepatitis B reactivation following switch away from tenofovir-containing antiretroviral therapy in people living with HIV: A case series & lessons for practice»
(Thank you @josephmarcusid.medsky.social for flagging it)
academic.oup.com/cid/article/...
Reposted by Stephen Vaughan
A mosquito-borne arbovirus, O’nyong’nong virus (ONNV) is an acute febrile illness w/HA, large joint pains, +/- rash & LAD.
It was identified in 1959 but remains relatively rare, partially due to limited diagnostics. These are the 1st reported Nigerian cases… #IDSky
academic.oup.com/cid/article/...
It was identified in 1959 but remains relatively rare, partially due to limited diagnostics. These are the 1st reported Nigerian cases… #IDSky
academic.oup.com/cid/article/...
O’nyong’nyong Virus Infections in Nigeria: A Case Series
Abstract. We report seven patients with detected o’nyong’nong virus infection, presenting with acute febrile illness at two tertiary hospitals in Nigeria.
academic.oup.com
November 21, 2025 at 1:48 PM
A mosquito-borne arbovirus, O’nyong’nong virus (ONNV) is an acute febrile illness w/HA, large joint pains, +/- rash & LAD.
It was identified in 1959 but remains relatively rare, partially due to limited diagnostics. These are the 1st reported Nigerian cases… #IDSky
academic.oup.com/cid/article/...
It was identified in 1959 but remains relatively rare, partially due to limited diagnostics. These are the 1st reported Nigerian cases… #IDSky
academic.oup.com/cid/article/...
Reposted by Stephen Vaughan
Another #Marburg vaccine💉candidate originated in Canada's National Microbiology Lab 20yrs ago (alongside the 1st #Ebola vaccine).
It's only now approaching clinical trials c/o IAVI w/ US BARDA funding.
Will the new HERC agency, described as Canada's BARDA, better support Cdn innovation end-to-end?
It's only now approaching clinical trials c/o IAVI w/ US BARDA funding.
Will the new HERC agency, described as Canada's BARDA, better support Cdn innovation end-to-end?
November 15, 2025 at 8:36 AM
Reposted by Stephen Vaughan
A 37-year-old man in Chad presented with a fever and a headache. An extensive evaluation identified a mammarenavirus, close to Lassa virus, in samples of cerebrospinal fluid. Read the full report: nej.md/47Uh3eM
#MedSky #IDSky
#MedSky #IDSky
November 15, 2025 at 2:01 PM
A 37-year-old man in Chad presented with a fever and a headache. An extensive evaluation identified a mammarenavirus, close to Lassa virus, in samples of cerebrospinal fluid. Read the full report: nej.md/47Uh3eM
#MedSky #IDSky
#MedSky #IDSky
Reposted by Stephen Vaughan
Performance of Diagnostic Tests for Histoplasmosis Across Clinical Syndromes and Immune Statuses
Nico Barros et al @ MiraVista
academic.oup.com/ofid/advance...
Nico Barros et al @ MiraVista
academic.oup.com/ofid/advance...
November 13, 2025 at 10:43 PM
Performance of Diagnostic Tests for Histoplasmosis Across Clinical Syndromes and Immune Statuses
Nico Barros et al @ MiraVista
academic.oup.com/ofid/advance...
Nico Barros et al @ MiraVista
academic.oup.com/ofid/advance...
Reposted by Stephen Vaughan
I’ve been in Toronto at the #astmh meeting these past few days and last night some very good news was presented here: A new malaria drug has proven efficacious in a large trial and could soon be approved.🧪
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
‘A sigh of relief’: New malaria drug succeeds in large clinical trial
As existing drugs falter because of resistance, the world gets a backup—but hard choices loom on how to use it
www.science.org
November 13, 2025 at 1:27 PM
I’ve been in Toronto at the #astmh meeting these past few days and last night some very good news was presented here: A new malaria drug has proven efficacious in a large trial and could soon be approved.🧪
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
My story in @science.org (and 🧵on why it's important to come):
www.science.org/content/arti...
Reposted by Stephen Vaughan
NY (Long Island) just confirmed local chikungunya transmission. One case is one case - not a growing outbreak - ongoing vector control and colder temps should keep it that way. Still: the illness is painful: terrible joint pain and when it spreads it spreads fast 1/n www.nytimes.com/2025/10/14/n...
New York Confirms State’s First Locally Acquired Case of Chikungunya
www.nytimes.com
October 15, 2025 at 1:20 PM
NY (Long Island) just confirmed local chikungunya transmission. One case is one case - not a growing outbreak - ongoing vector control and colder temps should keep it that way. Still: the illness is painful: terrible joint pain and when it spreads it spreads fast 1/n www.nytimes.com/2025/10/14/n...