Tobias Rausch
@trausch.bsky.social
Genomics, Bioinformatics.
github.com/tobiasrausch
github.com/tobiasrausch
Reposted by Tobias Rausch
I want to spell this out in case the implications aren't clear:
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
November 7, 2025 at 2:41 PM
I want to spell this out in case the implications aren't clear:
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
Reposted by Tobias Rausch
Can an AI tool help us better understand the origins of cancer?
Researchers from EMBL's Korbel Group have developed a new AI method – MAGIC – which, through a game of molecular laser tag, is shedding light on how chromosomal abnormalities form in cells.
www.embl.org/news/science...
Researchers from EMBL's Korbel Group have developed a new AI method – MAGIC – which, through a game of molecular laser tag, is shedding light on how chromosomal abnormalities form in cells.
www.embl.org/news/science...
October 29, 2025 at 4:11 PM
Can an AI tool help us better understand the origins of cancer?
Researchers from EMBL's Korbel Group have developed a new AI method – MAGIC – which, through a game of molecular laser tag, is shedding light on how chromosomal abnormalities form in cells.
www.embl.org/news/science...
Researchers from EMBL's Korbel Group have developed a new AI method – MAGIC – which, through a game of molecular laser tag, is shedding light on how chromosomal abnormalities form in cells.
www.embl.org/news/science...
Reposted by Tobias Rausch
Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Team Leader – Genomics Core Facility and Method Development
Are you ready to lead a cutting-edge Genomics Core facility while developing state of the art genomics methods? Join us at EMBL! We are seeking talented scientists to develop and lead a cutting-edge G...
embl.wd103.myworkdayjobs.com
August 11, 2025 at 9:54 AM
Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Tobias Rausch
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
August 7, 2025 at 8:28 AM
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Reposted by Tobias Rausch
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Group Leader - Genome Biology Unit
Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 1:41 PM
To all post-docs: The Genome Biology dept @embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Very nice summary of our latest paper by @samarendra-pani.bsky.social Thanks for all your hard work and outstanding contributions to this project!
[1/8] *New Open-Access Long Read Resource*. We sequenced 1,019 genomes from the 1000 Genomes Project sample cohort using @nanoporetech.com long-read sequencing (LRS) to median 17x coverage. Publication at go.nature.com/4ffPb8f.
@hhu.de @crg.eu @embl.org @impvienna.bsky.social
@hhu.de @crg.eu @embl.org @impvienna.bsky.social
July 24, 2025 at 9:48 AM
Very nice summary of our latest paper by @samarendra-pani.bsky.social Thanks for all your hard work and outstanding contributions to this project!
Reposted by Tobias Rausch
Two papers in today's issue of @nature.com : 1) we assemble 65 genomes to near completion, including centromeres and the MHC. tinyurl.com/3huhax6w. 2) we sequence 1,019 genomes from the 1kGP with long reads, revealing SVs down to low allele frequencies tinyurl.com/wbx3we9x.
Complex genetic variation in nearly complete human genomes - Nature
Using sequencing and haplotype-resolved assembly of 65 diverse human genomes, complex regions including the major histocompatibility complex and centromeres are analysed.
tinyurl.com
July 23, 2025 at 3:12 PM
Two papers in today's issue of @nature.com : 1) we assemble 65 genomes to near completion, including centromeres and the MHC. tinyurl.com/3huhax6w. 2) we sequence 1,019 genomes from the 1kGP with long reads, revealing SVs down to low allele frequencies tinyurl.com/wbx3we9x.
Reposted by Tobias Rausch
EMBL researchers and their collaborators have provided exciting new insights into human genetic variation by building upon the 1000 Genomes Project dataset.
The two studies constitute what may be the most complete overview of the human genome to date.
www.embl.org/news/science...
The two studies constitute what may be the most complete overview of the human genome to date.
www.embl.org/news/science...
July 23, 2025 at 3:20 PM
EMBL researchers and their collaborators have provided exciting new insights into human genetic variation by building upon the 1000 Genomes Project dataset.
The two studies constitute what may be the most complete overview of the human genome to date.
www.embl.org/news/science...
The two studies constitute what may be the most complete overview of the human genome to date.
www.embl.org/news/science...
Reposted by Tobias Rausch
Sorry guys, I can't come out to play, I have to read the new paper by Gene Meyers, Richard Durbin and Chenxi Zhou!
FastGA: Fast Genome Alignment www.biorxiv.org/content/10.1... 🧬🖥️🧪 www.github.com/thegenemyers...
June 20, 2025 at 12:18 PM
Sorry guys, I can't come out to play, I have to read the new paper by Gene Meyers, Richard Durbin and Chenxi Zhou!
Reposted by Tobias Rausch
Now published! Note that since Vikram's original post (quoted here), he's made it easy to dynamically update a set of multi-MUMs (e.g. when more genomes are added to a pangenome) and to find multi-MUMs for huge collections like HPRCv2 genomebiology.biomedcentral.com/articles/10....
June 17, 2025 at 2:02 PM
Now published! Note that since Vikram's original post (quoted here), he's made it easy to dynamically update a set of multi-MUMs (e.g. when more genomes are added to a pangenome) and to find multi-MUMs for huge collections like HPRCv2 genomebiology.biomedcentral.com/articles/10....
Reposted by Tobias Rausch
The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
📢 HPRC Release 2 is here!
Now with phased genomes from 200+ individuals, a 5x increase from Release 1.
Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:
humanpangenome.org/hprc-data-re...
Now with phased genomes from 200+ individuals, a 5x increase from Release 1.
Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:
humanpangenome.org/hprc-data-re...
May 12, 2025 at 1:52 PM
The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
Reposted by Tobias Rausch
SPECIAL ISSUE Part 2! This month @genomeresearch.bsky.social publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches.
tinyurl.com/Genome-Res-3...
tinyurl.com/Genome-Res-3...
April 14, 2025 at 7:54 PM
SPECIAL ISSUE Part 2! This month @genomeresearch.bsky.social publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches.
tinyurl.com/Genome-Res-3...
tinyurl.com/Genome-Res-3...
Reposted by Tobias Rausch
If you’re a #cancer researcher looking to use high throughput sequencing and single-cell technologies, then this course is for you! Make sure you've applied by 9 Feb:
www.ebi.ac.uk/training/eve...
Some financial assistance is available. See the course page for more info.
#OncSky #GeneSky 🧪🖥️🧬
www.ebi.ac.uk/training/eve...
Some financial assistance is available. See the course page for more info.
#OncSky #GeneSky 🧪🖥️🧬
January 30, 2025 at 9:29 AM
If you’re a #cancer researcher looking to use high throughput sequencing and single-cell technologies, then this course is for you! Make sure you've applied by 9 Feb:
www.ebi.ac.uk/training/eve...
Some financial assistance is available. See the course page for more info.
#OncSky #GeneSky 🧪🖥️🧬
www.ebi.ac.uk/training/eve...
Some financial assistance is available. See the course page for more info.
#OncSky #GeneSky 🧪🖥️🧬
Reposted by Tobias Rausch
On #WorldCancerDay, we feature how EMBL’s research & services are aiding the fight against cancer.
From prediction methods to studying cancer mechanisms – every discovery advances our collective knowledge about this global health challenge.
👇 Learn more:
www.embl.org/news/tag/can...
🧪 #cansky
From prediction methods to studying cancer mechanisms – every discovery advances our collective knowledge about this global health challenge.
👇 Learn more:
www.embl.org/news/tag/can...
🧪 #cansky
February 4, 2025 at 1:12 PM
On #WorldCancerDay, we feature how EMBL’s research & services are aiding the fight against cancer.
From prediction methods to studying cancer mechanisms – every discovery advances our collective knowledge about this global health challenge.
👇 Learn more:
www.embl.org/news/tag/can...
🧪 #cansky
From prediction methods to studying cancer mechanisms – every discovery advances our collective knowledge about this global health challenge.
👇 Learn more:
www.embl.org/news/tag/can...
🧪 #cansky
Reposted by Tobias Rausch
Recruitment for the EMBL International PhD Programme is officially open! 🔊
At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry & other sectors. Start your career in the life sciences with us!
www.embl.org/about/info/e...
🧪 #AcademicSky #careers
At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry & other sectors. Start your career in the life sciences with us!
www.embl.org/about/info/e...
🧪 #AcademicSky #careers
January 27, 2025 at 8:38 AM
Recruitment for the EMBL International PhD Programme is officially open! 🔊
At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry & other sectors. Start your career in the life sciences with us!
www.embl.org/about/info/e...
🧪 #AcademicSky #careers
At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry & other sectors. Start your career in the life sciences with us!
www.embl.org/about/info/e...
🧪 #AcademicSky #careers
Reposted by Tobias Rausch
"Fakten sind das Rückgrat unserer Demokratie."
Hier ein Aufruf, der gerne geteilt werden darf:
www.openpetition.de/petition/onl...
Hier ein Aufruf, der gerne geteilt werden darf:
www.openpetition.de/petition/onl...
Fakten sind das Rückgrat unserer Demokratie - Online-Petition
Liebe Mitbürgerinnen und Mitbürger, als Wissenschaftlerinnen und Wissenschaftler arbeiten wir täglich daran, die Grundlagen für fundierte Entscheidungen und Innovationen zu schaffen – basierend auf üb...
www.openpetition.de
January 20, 2025 at 2:07 PM
"Fakten sind das Rückgrat unserer Demokratie."
Hier ein Aufruf, der gerne geteilt werden darf:
www.openpetition.de/petition/onl...
Hier ein Aufruf, der gerne geteilt werden darf:
www.openpetition.de/petition/onl...
Reposted by Tobias Rausch
Around genomics, I am looking forward to large scale long read datasets - both Oxford Nanopore and PacBio (COI: I am long established consultant to Oxford Nanopore) where we can get "full" genome representation both for germline and somatic cases. This will transform repeat+structural variant calls
January 3, 2025 at 6:46 PM
Around genomics, I am looking forward to large scale long read datasets - both Oxford Nanopore and PacBio (COI: I am long established consultant to Oxford Nanopore) where we can get "full" genome representation both for germline and somatic cases. This will transform repeat+structural variant calls
I also deactivated mine.
January 11, 2025 at 11:53 AM
I also deactivated mine.
Reposted by Tobias Rausch
Athenaeum Dietrich Götze Stiftung has generously supported EMBL’s childhood leukaemia research. 🧪
Scientists hope that cell markers they discovered help to understand disease relapse better and lead to more effective treatment. #EMBL50 #MolBiol #Leukemia
www.embl.org/news/connect...
Scientists hope that cell markers they discovered help to understand disease relapse better and lead to more effective treatment. #EMBL50 #MolBiol #Leukemia
www.embl.org/news/connect...
12 moments of philanthropy: #12 New frontiers in childhood cancer research | EMBL
The Athenaeum Dietrich Götze Stiftung fuels impactful EMBL research that aims to better understand treatment-resistant childhood leukaemia.
www.embl.org
January 8, 2025 at 10:52 AM
Athenaeum Dietrich Götze Stiftung has generously supported EMBL’s childhood leukaemia research. 🧪
Scientists hope that cell markers they discovered help to understand disease relapse better and lead to more effective treatment. #EMBL50 #MolBiol #Leukemia
www.embl.org/news/connect...
Scientists hope that cell markers they discovered help to understand disease relapse better and lead to more effective treatment. #EMBL50 #MolBiol #Leukemia
www.embl.org/news/connect...
Reposted by Tobias Rausch
Before Christmas I did threads on the application areas of genomics in rare disease (bsky.app/profile/ewan...) and in common disease (bsky.app/profile/ewan...) - now I am going to focus on Cancer genomics
I want to provide an overview and perspective of rare disease genomic testing, which is a real success story of science impacting health - a science which goes back over 100 years and yet is still striding forward and much more to come.
January 4, 2025 at 2:07 PM
Before Christmas I did threads on the application areas of genomics in rare disease (bsky.app/profile/ewan...) and in common disease (bsky.app/profile/ewan...) - now I am going to focus on Cancer genomics
Reposted by Tobias Rausch
Sometimes you just have to persevere through negative reviews. Reviewers, please be kind :) #methodsmatter bit.ly/gs2-scholar
November 25, 2024 at 3:05 AM
Sometimes you just have to persevere through negative reviews. Reviewers, please be kind :) #methodsmatter bit.ly/gs2-scholar
Reposted by Tobias Rausch
The preliminary #eshg25 program is online. Stellar line-up of invited speakers - full breadth of our amazing field. Grateful to a wonderful SPC @eshg that made this possible. See you all in Milan next year!
2025.eshg.org/programme-at...
2025.eshg.org/programme-at...
Programme at a Glance
Pre-conference courses
Thursday, May 22, 2025 & Friday, May 23, 2025 - TBA
Conference programme
Saturday, May 24, 2025
08:30 - 10:00
Educational Sessions E01
E01 Single cell genomics and diseases
W...
2025.eshg.org
November 18, 2024 at 9:15 PM
The preliminary #eshg25 program is online. Stellar line-up of invited speakers - full breadth of our amazing field. Grateful to a wonderful SPC @eshg that made this possible. See you all in Milan next year!
2025.eshg.org/programme-at...
2025.eshg.org/programme-at...