Javier Márquez Ruiz
@translationalbrainstim.com
🧠 Neuroscientist | Brain Stimulation Researcher
🔬 Associate Professor at Universidad Pablo de Olavide (Seville)
⚡ Exploring tACS, tDCS, neuromodulation
🎸 Guitar & Bass player | 🏃 Runner | 📚 Reader | 🚀 Sci-Fi Enthusiast
🌐 Lab: translationalbrainstim.com
🔬 Associate Professor at Universidad Pablo de Olavide (Seville)
⚡ Exploring tACS, tDCS, neuromodulation
🎸 Guitar & Bass player | 🏃 Runner | 📚 Reader | 🚀 Sci-Fi Enthusiast
🌐 Lab: translationalbrainstim.com
Pinned
Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice
The neuromodulatory effects of cerebellar tDCS depend on Purkinje cell somatodendritic orientation relative to the electric field, revealing a key factor for optimizing stimulation protocols and compu...
elifesciences.org
📢 Just published in @elife.bsky.social !
💡 Ever wondered why cerebellar tDCS sometimes works—and sometimes doesn’t? Our new study reveals a key piece of the puzzle. 🧵
elifesciences.org/articles/100...
💡 Ever wondered why cerebellar tDCS sometimes works—and sometimes doesn’t? Our new study reveals a key piece of the puzzle. 🧵
elifesciences.org/articles/100...
Reposted by Javier Márquez Ruiz
Electrical #BrainStimulation can be used to modulate #brain activity but how does it affect the #CorticalLayers? This study shows that only the deeper layers show phase-dependent changes in local field potential components upon electrical stimulation @plosbiology.org 🧪 plos.io/406W3i5
July 9, 2025 at 8:32 AM
Electrical #BrainStimulation can be used to modulate #brain activity but how does it affect the #CorticalLayers? This study shows that only the deeper layers show phase-dependent changes in local field potential components upon electrical stimulation @plosbiology.org 🧪 plos.io/406W3i5
📢 Just published in Frontiers in Neuroscience!
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
Frontiers | Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
The balance between excitatory and inhibitory (E/I) activity is a fundamental property of neural circuits, ensuring precise information processing and preven...
doi.org
July 18, 2025 at 8:42 AM
📢 Just published in Frontiers in Neuroscience!
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
🧠⚡ Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models
🧵1/
🚨 New preprint out!
We investigated how cerebellar transcranial direct current stimulation (Cb-tDCS) modulates sensory processing both locally in Crus I/II and distally in primary somatosensory cortex (S1) in awake mice.
📄 www.biorxiv.org/content/10.1...
🚨 New preprint out!
We investigated how cerebellar transcranial direct current stimulation (Cb-tDCS) modulates sensory processing both locally in Crus I/II and distally in primary somatosensory cortex (S1) in awake mice.
📄 www.biorxiv.org/content/10.1...
Cerebellar tDCS differentially modulates sensory inputs in somatosensory cortex and cerebellum
Cerebellar transcranial direct-current stimulation (Cb-tDCS) is a promising tool for non-invasive modulation of cerebellar activity and has been proposed for the treatment of cerebellum-related disord...
www.biorxiv.org
June 30, 2025 at 9:17 AM
🧵1/
🚨 New preprint out!
We investigated how cerebellar transcranial direct current stimulation (Cb-tDCS) modulates sensory processing both locally in Crus I/II and distally in primary somatosensory cortex (S1) in awake mice.
📄 www.biorxiv.org/content/10.1...
🚨 New preprint out!
We investigated how cerebellar transcranial direct current stimulation (Cb-tDCS) modulates sensory processing both locally in Crus I/II and distally in primary somatosensory cortex (S1) in awake mice.
📄 www.biorxiv.org/content/10.1...
Reposted by Javier Márquez Ruiz
Amazing postdoctoral position at Pernaute’s lab
Fully funded for 3 year by European Research Council (#ERC) grant EARLYFATE #ERCCoG
At the #CABD a research center recognized with a national excellence award ‘María de Maeztu’ located in Seville, Spain
Share or apply
#JobOffer
#Postdoctoraljob
Fully funded for 3 year by European Research Council (#ERC) grant EARLYFATE #ERCCoG
At the #CABD a research center recognized with a national excellence award ‘María de Maeztu’ located in Seville, Spain
Share or apply
#JobOffer
#Postdoctoraljob
🚨🚨#Hiring!
3 year #postdoc position open in my lab @cabd-upo-csic.bsky.social to study the interplay between DNA damage responses and #preimplantation embryo development. Fully funded by EARLYFATE #ERCCoG
📆 Apply by 23rd May 2023
🔗Details below
@sebioldev.bsky.social
Please RT!🙏
3 year #postdoc position open in my lab @cabd-upo-csic.bsky.social to study the interplay between DNA damage responses and #preimplantation embryo development. Fully funded by EARLYFATE #ERCCoG
📆 Apply by 23rd May 2023
🔗Details below
@sebioldev.bsky.social
Please RT!🙏
April 23, 2025 at 7:44 PM
Amazing postdoctoral position at Pernaute’s lab
Fully funded for 3 year by European Research Council (#ERC) grant EARLYFATE #ERCCoG
At the #CABD a research center recognized with a national excellence award ‘María de Maeztu’ located in Seville, Spain
Share or apply
#JobOffer
#Postdoctoraljob
Fully funded for 3 year by European Research Council (#ERC) grant EARLYFATE #ERCCoG
At the #CABD a research center recognized with a national excellence award ‘María de Maeztu’ located in Seville, Spain
Share or apply
#JobOffer
#Postdoctoraljob
Reposted by Javier Márquez Ruiz
Finally out! Check my previous thread for a quick look:
bsky.app/profile/carl...
In @elife.bsky.social: Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice doi.org/10.7554/eLif...
bsky.app/profile/carl...
In @elife.bsky.social: Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice doi.org/10.7554/eLif...
April 21, 2025 at 9:07 PM
Finally out! Check my previous thread for a quick look:
bsky.app/profile/carl...
In @elife.bsky.social: Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice doi.org/10.7554/eLif...
bsky.app/profile/carl...
In @elife.bsky.social: Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice doi.org/10.7554/eLif...
📢 Just published in @elife.bsky.social !
💡 Ever wondered why cerebellar tDCS sometimes works—and sometimes doesn’t? Our new study reveals a key piece of the puzzle. 🧵
elifesciences.org/articles/100...
💡 Ever wondered why cerebellar tDCS sometimes works—and sometimes doesn’t? Our new study reveals a key piece of the puzzle. 🧵
elifesciences.org/articles/100...
Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice
The neuromodulatory effects of cerebellar tDCS depend on Purkinje cell somatodendritic orientation relative to the electric field, revealing a key factor for optimizing stimulation protocols and compu...
elifesciences.org
April 21, 2025 at 3:39 PM
📢 Just published in @elife.bsky.social !
💡 Ever wondered why cerebellar tDCS sometimes works—and sometimes doesn’t? Our new study reveals a key piece of the puzzle. 🧵
elifesciences.org/articles/100...
💡 Ever wondered why cerebellar tDCS sometimes works—and sometimes doesn’t? Our new study reveals a key piece of the puzzle. 🧵
elifesciences.org/articles/100...
Reposted by Javier Márquez Ruiz
My lab is hiring a pre-doctoral research assistant to work on the neural computations of foraging, seeking common cross-species algorithms. A BBSRC-funded project in collaboration with Matt Apps (Birmingham) & Nathan Lepora (Bristol)
Closes May 5th
Pls share!
jobs.nottingham.ac.uk/vacancy.aspx...
Closes May 5th
Pls share!
jobs.nottingham.ac.uk/vacancy.aspx...
Job Vacancy at the University of Nottingham: Research Assistant (Fixed Term)
We seek a predoctoral research assistant to join the Humphries’ group at the University of Nottingham on a BBSRC-funded project to study the neural basis of foraging, in collaboration with the groups ...
jobs.nottingham.ac.uk
April 8, 2025 at 9:18 AM
My lab is hiring a pre-doctoral research assistant to work on the neural computations of foraging, seeking common cross-species algorithms. A BBSRC-funded project in collaboration with Matt Apps (Birmingham) & Nathan Lepora (Bristol)
Closes May 5th
Pls share!
jobs.nottingham.ac.uk/vacancy.aspx...
Closes May 5th
Pls share!
jobs.nottingham.ac.uk/vacancy.aspx...
🧠✨ New publication!
Can we harness gamma oscillations to treat neurodegeneration?
#Neurostimulation #Neuroscience #Neurodegeneration #BrainOscillations #tACS
📖 Read the full open-access article:
Can we harness gamma oscillations to treat neurodegeneration?
#Neurostimulation #Neuroscience #Neurodegeneration #BrainOscillations #tACS
📖 Read the full open-access article:
Frontiers | Preclinical insights into gamma-tACS: foundations for clinical translation in neurodegenerative diseases
www.frontiersin.org
April 4, 2025 at 3:21 PM
🧠✨ New publication!
Can we harness gamma oscillations to treat neurodegeneration?
#Neurostimulation #Neuroscience #Neurodegeneration #BrainOscillations #tACS
📖 Read the full open-access article:
Can we harness gamma oscillations to treat neurodegeneration?
#Neurostimulation #Neuroscience #Neurodegeneration #BrainOscillations #tACS
📖 Read the full open-access article:
Reposted by Javier Márquez Ruiz
It's been some years...
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
doi.org/10.3389/fnci...
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
doi.org/10.3389/fnci...
Frontiers | Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
Astrocytes elicit transient Ca2+ elevations induced by G protein-coupled receptors (GPCRs), yet their role in vivo remains unknown. To address this, transgen...
doi.org
April 3, 2025 at 3:35 PM
It's been some years...
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
doi.org/10.3389/fnci...
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
doi.org/10.3389/fnci...
Reposted by Javier Márquez Ruiz
Congratulations to the artists/scientists, winners of #NeuroArt2025!
www.senc.es/concurso-neu...
@unisevilla.bsky.social @institutocajal.bsky.social @ibis-investigacion.bsky.social
@bellamoraromero.bsky.social @jsromero.bsky.social @navarrete-llinas.bsky.social
www.senc.es/concurso-neu...
@unisevilla.bsky.social @institutocajal.bsky.social @ibis-investigacion.bsky.social
@bellamoraromero.bsky.social @jsromero.bsky.social @navarrete-llinas.bsky.social
March 25, 2025 at 10:46 AM
Congratulations to the artists/scientists, winners of #NeuroArt2025!
www.senc.es/concurso-neu...
@unisevilla.bsky.social @institutocajal.bsky.social @ibis-investigacion.bsky.social
@bellamoraromero.bsky.social @jsromero.bsky.social @navarrete-llinas.bsky.social
www.senc.es/concurso-neu...
@unisevilla.bsky.social @institutocajal.bsky.social @ibis-investigacion.bsky.social
@bellamoraromero.bsky.social @jsromero.bsky.social @navarrete-llinas.bsky.social
Reposted by Javier Márquez Ruiz
Human cortical pyramidal neurons are larger, with more elaborate branching, and distinct nonlinear biophysical properties compared to rat cortical pyramidal neurons.
Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)
Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)
December 26, 2024 at 5:31 PM
Human cortical pyramidal neurons are larger, with more elaborate branching, and distinct nonlinear biophysical properties compared to rat cortical pyramidal neurons.
Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)
Are they more functionally complex? Could that boost the human brain’s computational power? and is that what makes us human? (1/11)
Reposted by Javier Márquez Ruiz
🤖📚 ¿Puede la #IA transformar la #universidad?
Hablaremos sobre datos, ética, regulación y futuro en la Gestión Pública Universitaria.
📅 24 de abril
📍 Paraninfo UPO (presencial y online)
🔗 eventos.upo.es/e/164170
#SeminarioUPO #IAEnLaGestión #innovaciónuniversitaria
Hablaremos sobre datos, ética, regulación y futuro en la Gestión Pública Universitaria.
📅 24 de abril
📍 Paraninfo UPO (presencial y online)
🔗 eventos.upo.es/e/164170
#SeminarioUPO #IAEnLaGestión #innovaciónuniversitaria
March 28, 2025 at 1:14 PM
🤖📚 ¿Puede la #IA transformar la #universidad?
Hablaremos sobre datos, ética, regulación y futuro en la Gestión Pública Universitaria.
📅 24 de abril
📍 Paraninfo UPO (presencial y online)
🔗 eventos.upo.es/e/164170
#SeminarioUPO #IAEnLaGestión #innovaciónuniversitaria
Hablaremos sobre datos, ética, regulación y futuro en la Gestión Pública Universitaria.
📅 24 de abril
📍 Paraninfo UPO (presencial y online)
🔗 eventos.upo.es/e/164170
#SeminarioUPO #IAEnLaGestión #innovaciónuniversitaria
Reposted by Javier Márquez Ruiz
FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!
Albert Einstein College of Medicine | Medical Education | Biomedical Research
faculty-einstein.icims.com
March 26, 2025 at 5:52 PM
FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!
🧠 La @pablodeolavide.upo.es acogerá las Jornadas de Estimulación Cerebral 2025 los días 26-27 de mayo.
Más de 100 expertos en neurociencia debatirán sobre el futuro de la estimulación cerebral no invasiva.
📍 Paraninfo UPO | 📨 2022aedes@gmail.com
#BrainStimulation #tDCS #TMS #NIBS #Neuroscience
Más de 100 expertos en neurociencia debatirán sobre el futuro de la estimulación cerebral no invasiva.
📍 Paraninfo UPO | 📨 2022aedes@gmail.com
#BrainStimulation #tDCS #TMS #NIBS #Neuroscience
March 26, 2025 at 10:14 AM
🧠 La @pablodeolavide.upo.es acogerá las Jornadas de Estimulación Cerebral 2025 los días 26-27 de mayo.
Más de 100 expertos en neurociencia debatirán sobre el futuro de la estimulación cerebral no invasiva.
📍 Paraninfo UPO | 📨 2022aedes@gmail.com
#BrainStimulation #tDCS #TMS #NIBS #Neuroscience
Más de 100 expertos en neurociencia debatirán sobre el futuro de la estimulación cerebral no invasiva.
📍 Paraninfo UPO | 📨 2022aedes@gmail.com
#BrainStimulation #tDCS #TMS #NIBS #Neuroscience
🚨 Our revised paper is now available in eLife! 🚨
We show that Purkinje cell orientation determines the polarity-dependent modulation of their firing rate during cerebellar tDCS in awake mice.
🧠✨ Check it out!
@elife.bsky.social
#tDCS #Cerebellum #PurkinjeCells #BrainStimulation #Neuroscience
We show that Purkinje cell orientation determines the polarity-dependent modulation of their firing rate during cerebellar tDCS in awake mice.
🧠✨ Check it out!
@elife.bsky.social
#tDCS #Cerebellum #PurkinjeCells #BrainStimulation #Neuroscience
Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice
doi.org
March 26, 2025 at 9:07 AM
🚨 Our revised paper is now available in eLife! 🚨
We show that Purkinje cell orientation determines the polarity-dependent modulation of their firing rate during cerebellar tDCS in awake mice.
🧠✨ Check it out!
@elife.bsky.social
#tDCS #Cerebellum #PurkinjeCells #BrainStimulation #Neuroscience
We show that Purkinje cell orientation determines the polarity-dependent modulation of their firing rate during cerebellar tDCS in awake mice.
🧠✨ Check it out!
@elife.bsky.social
#tDCS #Cerebellum #PurkinjeCells #BrainStimulation #Neuroscience