Tom Caniels
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tomcaniels.bsky.social
Tom Caniels
@tomcaniels.bsky.social
🧬 likes vaccines, viruses and antibodies at Amsterdam UMC
🎓 PhD cum laude in vaccinology, University of Amsterdam
Pinned
A little overdue, but in August we shared work on our HIV vaccine candidate in Science Immunology!

This vaccine is now in clinical trials... more on that (hopefully) soon 🤞 😄 What did we do...? ⬇️

https://buff.ly/4gxyqVi
Reposted by Tom Caniels
Phase 1 trial: a recombinant, SOSIP-stable germline-targeting HIV Env trimer adjuvanted with AS01B, induced VRC01-class bnAb precursors at high frequency that had undergone characteristic SHM @science.org @tomcaniels.bsky.social
www.science.org/doi/10.1126/...
May 15, 2025 at 8:27 PM
Reposted by Tom Caniels
If you're a grad student or an undergrad interested in research I need to you listen to me very carefully.

You cannot learn to write good research papers if you do not read good research papers.

Stop asking LLMs to summarize papers for you.
May 3, 2025 at 8:25 PM
Reposted by Tom Caniels
Cool germinal center acrobatics from Juhee Pae et al, check it out!

www.nature.com/articles/s41...
www.nature.com
March 19, 2025 at 5:08 PM
Reposted by Tom Caniels
Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes www.nature.com/articles/s41...
Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes - Nature Communications
Structurally convergent antibodies targeting the conserved influenza HA anchor epitope have provided a template for next-generation vaccine development. The authors identified four anchor antibodies e...
www.nature.com
February 7, 2025 at 12:18 PM
A little overdue, but in August we shared work on our HIV vaccine candidate in Science Immunology!

This vaccine is now in clinical trials... more on that (hopefully) soon 🤞 😄 What did we do...? ⬇️

https://buff.ly/4gxyqVi
February 3, 2025 at 11:10 AM
Reposted by Tom Caniels
Dont think I actually imagined it getting this bad so fast. Feeling completely lost and devastated for my NIH colleagues, trainees and all of us who rely on NIH for funding, guidance and scientific leadership. This will set the US back decades and lead to brain drain www.science.org/content/arti...
Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring
Researchers facing
www.science.org
January 23, 2025 at 1:53 AM