theNiessingLabs
theniessinglabs.bsky.social
theNiessingLabs
@theniessinglabs.bsky.social
We use structural biology, biochemistry, and (stem) cell biology to understand the roles of RNA-binding proteins in neurodevelopmental #PURA Syndrome and neurodegeneration. We are located at @uniulm.bsky.social and at @helmholtzmunich.bsky.social, Germany.
Reposted by theNiessingLabs
Von Bio-inspirierten Technologien über medizinische & gesellschaftliche Herausforderungen bis hin zur Neurochirurgie spannt sich der Bogen der Vortragsreihe der Ulmer Universitätsgesellschaft. Eintritt frei!🆓 t1p.de/uug_33 *stg #uulm
November 6, 2025 at 1:41 PM
We are so grateful! PURA Syndrome Deutschland e.V. makes donation to support our research on #PURA syndrome at @helmholtzmunich.bsky.social, #Rare #puraperfect.
October 29, 2025 at 10:17 AM
Had an exciting visit to the German University in Cairo (www.guc.edu.eg). I was impressed by how much this university contributes to mutual understanding between Europe and the Middle East through academic exchange. Much needed these days! Close collaboration with #UUlm and supported by #DAAD.
October 13, 2025 at 5:34 AM
Today we launched the #PURA Biobank at @www.helmholtz-munich.de for patients with #purasyndrome. Biosamples will support research and development of treatment strategies. Big thanks to PURA Syndrome Foundation USA for your constant support! #Rare #puraperfect www.helmholtz-munich.de/en/pura-biob...
June 28, 2025 at 9:22 PM
Great collaboration of Simone Heber and Anne Ephrussi with our lab on Staufen-dependent RNA localization!
If you are interested in cellular RNA transport, check out Simone Heber's first corresponding author paper: www.cell.com/cell-reports...
Very cool stuff about motor switching to get the transport direction right. Collaboration between the Ephrussi, Niessing. Hennig, Chao and Heber groups.
A direct interaction between the RNA-binding proteins Staufen and Tm1-I/C in the oskar mRNA transport complex
Gaber et al. identify a direct protein-protein interaction between the oskar mRNA transport particle components Staufen and Tropomyosin1-I/C. They map the interaction surface at amino acid resolution ...
www.cell.com
June 28, 2025 at 8:52 PM
We participated in Interact Munich 2025, where we had the opportunity to present our research through posters, connect with fellow young researchers, and attend inspiring talks. A big thank you to the organizing team for making such a fantastic event possible! #interact2025
April 10, 2025 at 9:58 AM
Lab work is important but also consumes lots of energy and resources. We are the first lab at @www.helmholtz-munich.de to be awarded with the Gold level LEAF (Laboratory Efficiency Assessment Framework) certificate of the @ucl.ac.uk for our efforts to become a more sustainable laboratory!
March 31, 2025 at 12:59 PM
Terrified by the global developments and current politics? We took a break from the world by attending a hip-hop dance class. Lots of excitement, confusion, and happiness. We can highly recommend it as a mental therapy...
February 27, 2025 at 8:44 AM
Reposted by theNiessingLabs
I Used to Run the N.I.H. Here’s What Worries Me.
www.nytimes.com/2025/02/14/o...
Opinion | American Science is Under Attack (Gift Article)
The Trump administration hobbles research and endangers the public health.
www.nytimes.com
February 15, 2025 at 5:15 AM
Reposted by theNiessingLabs
🚨 Early Bird Registration Closing Soon for Interact Munich 2025! 🚨

⏳ Don’t miss out! Our Early Bird pricing for Interact Munich 2025 ends on February 17th – secure your spot today and save on registration!
February 14, 2025 at 12:22 PM
Reposted by theNiessingLabs
Check out our recent work on CDS #m6A mediated RNA decay (CMD)! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Thank you @uniwuerzburg.bsky.social , @imbmainz.bsky.social and RMap🥳

www.cell.com/molecular-ce...
January 15, 2025 at 10:00 AM
Now out on bioRxiv: our collaboration with Simone Heber, Anne Ephrussi and Jeff Chao reveals how Staufen interacts with the kinesin adapter aTm1 to localize oskar mRNA in #Drosophila oocytes, modulating kinesin-1 dependent mRNA transport. #RNAsky #RNA doi.org/10.1101/2024...
January 9, 2025 at 9:08 AM
Reposted by theNiessingLabs
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month. We are very grateful for his service.
@jiwasa.bsky.social will continue the series, beginning with January's article on Assembly Line Polyketide Synthases
Details: cdn.rcsb.org/rcsb-pd...
EDUCATION CORNER: Molecule of the Month: Celebrating  25 Years of Storytelling and Announcing New Beginnings
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month series.  Janet Iwasa will be continuing the series for PDB-101.
cdn.rcsb.org
January 6, 2025 at 5:12 PM
Reposted by theNiessingLabs
🌟 Welcome to <interact> 2025 🌟
We’re thrilled to announce the most exciting student-organised scientific conference is back in 2025! 🎉

📅 Mark your calendars:
🗓️ April 3-4, 2025
📍 Venue: Biomedical Center (BMC), LMU Munich
December 5, 2024 at 12:41 PM
Hello Bluesky 🤠
Our very first post is about our recent paper in Nucleic Acids Research: so-called PUN motifs are repetitive elements enabling proteins to catalyze #RNA folding and RNA-dependent #condensate formation ( #LLPS). 15% of human proteins contain 3 or more PUN motifs. See bit.ly/4fZ3f54.
December 12, 2024 at 7:08 AM