Tara Fischer
@tarafisch.bsky.social
Molecular Cell Biologist. Organelles + immunity 🔬🧫🦠 Science + Labor 🤝 UAW Local 2750
Pinned
Tara Fischer
@tarafisch.bsky.social
· Dec 1
https://www.embopress.org/doi/full/10.1038/s44318-024-00291-2
t.co
Apropos *first* post! We’ve discovered a central mechanism for how activation of STING induces NFkB related immune signaling - M1-linked/linear ubiquitin chains! I’m so excited to share it with you all, out now in t.co/zCIf2E4h2z a thread 1/X:
Reposted by Tara Fischer
We are in the midst of an all-out attempt to exclude the global majority from science. Watson was clear about where he fell on that. I would trade every single dinner, meeting, seminar, fancy campus, and prestigious donor for my incredible friends to be safer. Their science is worth far more.
November 8, 2025 at 5:24 PM
We are in the midst of an all-out attempt to exclude the global majority from science. Watson was clear about where he fell on that. I would trade every single dinner, meeting, seminar, fancy campus, and prestigious donor for my incredible friends to be safer. Their science is worth far more.
Reposted by Tara Fischer
Jeremy, I have followed your science advocacy on this platform with respect, but I find this thread deeply hurtful and sad and I am going to tell you why. While my wife did her postdoc at CSHL, she and our many dear friends had to endure the racist rhetoric of this man, which did constant harm
On one evening, the speakers were divided up and went to dinner parties hosted by some of the wealthy folks who lived around Cold Spring Harbor on Long Island. My dinner was delightful, with good conversation with our host (the mayor of a nearby village), his friends, and some other speakers.
34/41
34/41
November 8, 2025 at 5:15 PM
Jeremy, I have followed your science advocacy on this platform with respect, but I find this thread deeply hurtful and sad and I am going to tell you why. While my wife did her postdoc at CSHL, she and our many dear friends had to endure the racist rhetoric of this man, which did constant harm
Reposted by Tara Fischer
A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
October 27, 2025 at 9:43 PM
A new, nerdy paper. We figured out (some) of the rules underlying cell-permeability of probes and designed ligands that light up, grab, and move proteins around. Awesome @hhmijanelia.bsky.social x @uwmadison.bsky.social x @stjuderesearch.bsky.social collaboration! www.pnas.org/doi/10.1073/...
Reposted by Tara Fischer
The cut rate labor business of grant funded academic science revealed in one tweet.
What I don’t understand here is how laboratories will continue to run without grad student labor- lab techs are paid similarly without the ability to get fellowships/training grants to defray costs. Postdocs are more expensive.
Wow. Harvard nuking its PhD programs
- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero
- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero
October 21, 2025 at 6:32 PM
The cut rate labor business of grant funded academic science revealed in one tweet.
Reposted by Tara Fischer
Dear all, A scientist from UNC Chapel Hill, Paul Maddox, is running for congress in NC for a seat currently held by a republican. If you care about science (and democracy) please consider donating to his campaign #Standupforscience secure.actblue.com/donate/paul-...
Donate to Paul Maddox for Congress in NC 11
Paul is running for Congress because there’s a sickness in Washington, and no one is working to cure it.
secure.actblue.com
October 20, 2025 at 5:51 PM
Dear all, A scientist from UNC Chapel Hill, Paul Maddox, is running for congress in NC for a seat currently held by a republican. If you care about science (and democracy) please consider donating to his campaign #Standupforscience secure.actblue.com/donate/paul-...
Reposted by Tara Fischer
Collaborative. Creative. Impactful. Come join us in Ann Arbor! For more information and application link see jobs.sciencecareers.org/job/675674/f...
October 19, 2025 at 5:53 PM
Collaborative. Creative. Impactful. Come join us in Ann Arbor! For more information and application link see jobs.sciencecareers.org/job/675674/f...
Reposted by Tara Fischer
IT'S ALMOST HERE!!
#NoKingsDay is around the corner. Gonna be a BIG event at @nihvigils.bsky.social and @27unihted.bsky.social We're going to play TWO SETS - one at the beginning and one at the end.
#fucktrump #punk #punkrock #resist #FightFascism #AntiAuthoritarian #FuckICE #FightTheNazis
#NoKingsDay is around the corner. Gonna be a BIG event at @nihvigils.bsky.social and @27unihted.bsky.social We're going to play TWO SETS - one at the beginning and one at the end.
#fucktrump #punk #punkrock #resist #FightFascism #AntiAuthoritarian #FuckICE #FightTheNazis
October 16, 2025 at 3:15 PM
IT'S ALMOST HERE!!
#NoKingsDay is around the corner. Gonna be a BIG event at @nihvigils.bsky.social and @27unihted.bsky.social We're going to play TWO SETS - one at the beginning and one at the end.
#fucktrump #punk #punkrock #resist #FightFascism #AntiAuthoritarian #FuckICE #FightTheNazis
#NoKingsDay is around the corner. Gonna be a BIG event at @nihvigils.bsky.social and @27unihted.bsky.social We're going to play TWO SETS - one at the beginning and one at the end.
#fucktrump #punk #punkrock #resist #FightFascism #AntiAuthoritarian #FuckICE #FightTheNazis
Reposted by Tara Fischer
I don’t know who needs to hear this but the CDC is being eviscerated right now. America is not going to have any kind of outbreak response capacity after tonight. Americans’ health data is no longer secure. Say goodbye to federal public health in any capacity. It’s a disaster. We won’t recover.
October 11, 2025 at 3:05 AM
I don’t know who needs to hear this but the CDC is being eviscerated right now. America is not going to have any kind of outbreak response capacity after tonight. Americans’ health data is no longer secure. Say goodbye to federal public health in any capacity. It’s a disaster. We won’t recover.
Reposted by Tara Fischer
NO TO ILLEGAL RIFS
TRUMP AND VOUGHT ARE HURTING AMERICA
Gather at the Office of Management and Budget (near WH, exact location to come)
Monday, October 13, 2pm
DM us if you were RIFed (or had coworkers who were RIFed) and would like to speak
TRUMP AND VOUGHT ARE HURTING AMERICA
Gather at the Office of Management and Budget (near WH, exact location to come)
Monday, October 13, 2pm
DM us if you were RIFed (or had coworkers who were RIFed) and would like to speak
October 11, 2025 at 2:50 PM
NO TO ILLEGAL RIFS
TRUMP AND VOUGHT ARE HURTING AMERICA
Gather at the Office of Management and Budget (near WH, exact location to come)
Monday, October 13, 2pm
DM us if you were RIFed (or had coworkers who were RIFed) and would like to speak
TRUMP AND VOUGHT ARE HURTING AMERICA
Gather at the Office of Management and Budget (near WH, exact location to come)
Monday, October 13, 2pm
DM us if you were RIFed (or had coworkers who were RIFed) and would like to speak
Amazing
October 9, 2025 at 2:36 AM
Amazing
Reposted by Tara Fischer
Some federal workers support the government shutdown, even as President Trump threatens to use this moment to lay off employees and cut funding to programs.
Why some federal workers aren't scared by the threat of shutdown layoffs
Some federal workers support the government shutdown, even as President Trump threatens to use this moment to lay off employees and cut funding to programs.
n.pr
October 7, 2025 at 11:57 AM
Some federal workers support the government shutdown, even as President Trump threatens to use this moment to lay off employees and cut funding to programs.
I signed @uthealthhouston.bsky.social alum!
Are you an alum outraged by Trump's attacks on universities? Defend your school now by signing this alumni petition in support of these 9 universities as well as campus communities across America. alumni.controlshift.app/petitions/tr...
Are you an alum outraged by Trump's attacks on universities? Defend your school now by signing this alumni petition in support of these 9 universities as well as campus communities across America. alumni.controlshift.app/petitions/tr...
Trump attacks 9 universities: Sign the alumni petition to defend your school now
Are you an alum outraged by Trump's attacks on universities? Defend your school now by signing this alumni petition in support of these 9 universities as well as campus communities across America.
alumni.controlshift.app
October 3, 2025 at 8:07 PM
I signed @uthealthhouston.bsky.social alum!
Are you an alum outraged by Trump's attacks on universities? Defend your school now by signing this alumni petition in support of these 9 universities as well as campus communities across America. alumni.controlshift.app/petitions/tr...
Are you an alum outraged by Trump's attacks on universities? Defend your school now by signing this alumni petition in support of these 9 universities as well as campus communities across America. alumni.controlshift.app/petitions/tr...
Reposted by Tara Fischer
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
October 2, 2025 at 5:11 PM
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
Reposted by Tara Fischer
That’s a lot of science we left on the table.
Here is NIDDK
61% as many new R01s in FY25 as in FY24.
17/n
61% as many new R01s in FY25 as in FY24.
17/n
October 3, 2025 at 4:33 AM
That’s a lot of science we left on the table.
Reposted by Tara Fischer
Being Ready to Lose Well, Perseverance and How Not to Be Lost talkingpointsmemo.com/edblog/being...
Being Ready to Lose Well, Perseverance and How Not to Be Lost
On Monday I saw a bunch of people on Bluesky mentioning and...
talkingpointsmemo.com
October 2, 2025 at 5:55 PM
Being Ready to Lose Well, Perseverance and How Not to Be Lost talkingpointsmemo.com/edblog/being...
Reposted by Tara Fischer
Reposted by Tara Fischer
This is sort of a classic prisoners' dilemma: If nobody defects, nobody has "priority". Which makes it essential that universities coordinate a united front.
Trump's higher ed ransom note is here - everyone would have to acquiesce to their unprecedented demands or not be "given priority for grants," plus they can demand "reimbursement" for "violations" www.wsj.com/us-news/educ...
A mechanism to enforce fealty. An attack on academic freedom and democracy
A mechanism to enforce fealty. An attack on academic freedom and democracy
October 2, 2025 at 5:35 PM
This is sort of a classic prisoners' dilemma: If nobody defects, nobody has "priority". Which makes it essential that universities coordinate a united front.
Reposted by Tara Fischer
This is extortion. Faculty, students, staff, alumni across the country need to get to their Presidents & Trustees today. Just say no. This blackmail only works if most everyone folds. Capitulation now means the end of American higher education for a generation. www.nytimes.com/2025/10/02/u...
Trump Administration Asks Colleges to Sign ‘Compact’ to Get Funding Preference
www.nytimes.com
October 2, 2025 at 9:55 AM
This is extortion. Faculty, students, staff, alumni across the country need to get to their Presidents & Trustees today. Just say no. This blackmail only works if most everyone folds. Capitulation now means the end of American higher education for a generation. www.nytimes.com/2025/10/02/u...
Reposted by Tara Fischer
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
October 1, 2025 at 6:21 PM
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
Reposted by Tara Fischer
BREAKING: WE WON!!!
💥 💥 💥
Federal Judge William G. Young ruled today in our lawsuit against the Trump administration that the policy of arresting, detaining, & deporting noncitizen students & faculty members for their pro-Palestinian advocacy violates the 1st Amendment.
Full ruling here:
💥 💥 💥
Federal Judge William G. Young ruled today in our lawsuit against the Trump administration that the policy of arresting, detaining, & deporting noncitizen students & faculty members for their pro-Palestinian advocacy violates the 1st Amendment.
Full ruling here:
Findings of Fact & Conclusions of Law – #261 in American Association of University Professors v. Rubio (D. Mass., 1:25-cv-10685) – CourtListener.com
Judge William G. Young: ORDER entered. FINDINGS OF FACT AND RULINGS OF LAW, PURSUANT TO FED. R. CIV. P. 52(A)(Sonnenberg, Elizabeth) (Additional attachment(s) added on 9/30/2025: # 1 Main Document) (J...
www.courtlistener.com
September 30, 2025 at 5:43 PM
BREAKING: WE WON!!!
💥 💥 💥
Federal Judge William G. Young ruled today in our lawsuit against the Trump administration that the policy of arresting, detaining, & deporting noncitizen students & faculty members for their pro-Palestinian advocacy violates the 1st Amendment.
Full ruling here:
💥 💥 💥
Federal Judge William G. Young ruled today in our lawsuit against the Trump administration that the policy of arresting, detaining, & deporting noncitizen students & faculty members for their pro-Palestinian advocacy violates the 1st Amendment.
Full ruling here:
Reposted by Tara Fischer
More than 5,000 federal workers (current and former) have now signed this letter urging "Congress to pass nothing less than a continuing resolution (CR) that reasserts Congress's constitutional powers, upholds our democracy and protects the American people."
Civil Servants Demand an End to Executive Overreach
Join federal workers from across the federal government as we urge Congress to pass nothing less than a continuing resolution (CR) that reasserts Congress's constitutional powers, upholds our democrac...
actionnetwork.org
September 29, 2025 at 5:11 PM
More than 5,000 federal workers (current and former) have now signed this letter urging "Congress to pass nothing less than a continuing resolution (CR) that reasserts Congress's constitutional powers, upholds our democracy and protects the American people."
Reposted by Tara Fischer
This is absolutely ridiculous, would devastate numerous academic fields, and would destroy the lives of people I love very much. Please, please join me in sending a comment in on this telling them so
DHS is proposing a rule that would end "duration of status" for J, F and other visa holders. This would decimate the international graduate student and postdoc population, which are a crucial part of the United States biomedical workforce. There's still time for you to comment on the proposed rule.
Establishing a Fixed Time Period of Admission and an Extension of Stay Procedure for Nonimmigrant Academic Students, Exchange Visitors, and Representatives of Foreign Information Media
Unlike most nonimmigrant classifications, which are admitted for a fixed time period, aliens in the F (academic student), J (exchange visitor), and most I (representatives of foreign information media...
www.federalregister.gov
September 29, 2025 at 2:55 PM
This is absolutely ridiculous, would devastate numerous academic fields, and would destroy the lives of people I love very much. Please, please join me in sending a comment in on this telling them so
Reposted by Tara Fischer
FUN (@fedworkersunited.bsky.social) is calling out the OMB memo threatening mass layoffs as a pressure tactic to get Congress to keep the federal government open.
Read the release: www.federalunionists.net/press/statem...
Read the release: www.federalunionists.net/press/statem...
September 25, 2025 at 7:28 PM
FUN (@fedworkersunited.bsky.social) is calling out the OMB memo threatening mass layoffs as a pressure tactic to get Congress to keep the federal government open.
Read the release: www.federalunionists.net/press/statem...
Read the release: www.federalunionists.net/press/statem...
Reposted by Tara Fischer
In @jcb.org, @lysoluis.bsky.social, @markrcookson.bsky.social et al. show how two distinct pRAB effectors and RHD members, JIP4 and RILPL1, provide antagonistic motor force to regulate #lysosome tubulation. rupress.org/jcb/article/...
September 24, 2025 at 5:10 PM
In @jcb.org, @lysoluis.bsky.social, @markrcookson.bsky.social et al. show how two distinct pRAB effectors and RHD members, JIP4 and RILPL1, provide antagonistic motor force to regulate #lysosome tubulation. rupress.org/jcb/article/...