Stanisław Dunin-Horkawicz
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staszekdh.bsky.social
Stanisław Dunin-Horkawicz
@staszekdh.bsky.social
Max Planck Institute for Biology, Tübingen & University of Warsaw. Using computational tools to study protein evolution and function.
Reposted by Stanisław Dunin-Horkawicz
"Exclusive: Medical journal rejects Kennedy's call for retraction of vaccine study"
Exclusive: Medical journal rejects Kennedy's call for retraction of vaccine study
An influential U.S. medical journal is rejecting a call from Health Secretary Robert F. Kennedy Jr. to retract a large Danish study that found that aluminum ingredients in vaccines do not increase health risks for children, the journal's editor told Reuters.
www.reuters.com
August 12, 2025 at 11:33 AM
I got followed by exactly the same dog from two different accounts. Are fake accounts becoming a problem on BS?
August 9, 2025 at 12:35 PM
Reposted by Stanisław Dunin-Horkawicz
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August 7, 2025 at 12:00 PM
Reposted by Stanisław Dunin-Horkawicz
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August 2, 2025 at 12:00 PM
Reposted by Stanisław Dunin-Horkawicz
I am #exhilarated to share that our new paper "LIGYSIS-web: a resource for the analysis of protein-ligand binding sites" is now published in @narjournal.bsky.social! After almost two years of development and more than 600 commits, LIGYSIS-web is out!

📜 : tinyurl.com/utges-LIGYSI...
May 19, 2025 at 10:37 AM
Reposted by Stanisław Dunin-Horkawicz
We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!
May 1, 2025 at 7:32 AM
Coiled coils (CCs) are protein domains in which alpha helices assemble into regular supercoiled bundles. In our new paper, we investigate how accurately AlphaFold2 predicts the oligomeric state, topology, and fine structural details of CC domains: onlinelibrary.wiley.com/doi/10.1002/....
December 17, 2024 at 5:24 PM
Reposted by Stanisław Dunin-Horkawicz
Large livestock facilities in states across the country have become epicenters of bird flu, and some researchers say that’s no surprise:

Putting thousands of animals together in confined, cramped barns or corrals creates a petri dish for virus to spread, according to WIRED.
December 15, 2024 at 2:11 PM
Reposted by Stanisław Dunin-Horkawicz
If talent and opportunity were equally distributed, the average #NobelPrize winner would come from a middle income background.

The reality? The average laureate grew up in a household just below the top 10%. More than 50% come from the top 5%.
🧪🎩💰
www.theguardian.com/commentisfre...
The science behind winning a Nobel Prize? Being a man from a wealthy family | Torsten Bell
A lot of talent is wasted in a world where more than half of laureates come from households in the richest 5%
www.theguardian.com
December 8, 2024 at 10:23 AM
Reposted by Stanisław Dunin-Horkawicz
New @science.org
from my Scripps Research colleagues on H5N1
A single mutation can increase the virus's binding to human receptors, highlighting the need for rigorous surveillance
science.org/doi/10.1126/...
December 5, 2024 at 7:02 PM
Reposted by Stanisław Dunin-Horkawicz
I have a PhD position available in my group, to start in March 2025. If you have a keen interest in biochemistry and would like to study an exciting and novel class of copper proteins (aka weird Cu tubes) from bacteria, I'd love to hear from you.
You should apply here: ibb.edu.pl/app/uploads/...
December 3, 2024 at 3:28 PM
Reposted by Stanisław Dunin-Horkawicz
Related to that, there is a fun PPI prediction challenge by @chembiobryan.bsky.social, which I'd like to advertise to everyone developing PPI prediction models. Tests like that are crucial for assessing model generalization capabilities!
www.dickinsonlab.uchicago.edu/ppi-challenge
PPI Challenge 1 | dickinson-group
www.dickinsonlab.uchicago.edu
November 28, 2024 at 9:31 AM
Reposted by Stanisław Dunin-Horkawicz
If you are interested or working in #structuralbiology, as you see any protein (yes, *any*), you should be thinking: is it glycosylated? The answer is likely to be yes! You can predict N-glycosylation sites and rebuild all types of glycans with ReGlyco glycoshape.org 😌
Check out the example ⬇️ 1/2
November 18, 2024 at 8:55 AM
How do you study a family of protein domains whose function depends on their dynamics? Let's model 5000 homologs with AlphaFold2 and see what happens. The case of dimeric HAMP domains of prokaryotic signal transduction proteins: onlinelibrary.wiley.com/doi/full/10....
January 5, 2024 at 4:07 PM
Reposted by Stanisław Dunin-Horkawicz
Our paper looking into the phenomenon of domain mosaicism in phages is now out in Nature Communications. Work led by Bogna Smug together with Krzysztof Szczepaniak, @epcrocha.bsky.social and @staszekdh.bsky.social. See a short thread. 1/7
www.nature.com/articles/s41...
Ongoing shuffling of protein fragments diversifies core viral functions linked to interactions with ...
Proteins are composed of distinct functional domains, each serving a specific role. Here, Smug et al. show that phages are able to shuffle fragments of their proteins and this predominantly occurs in ...
www.nature.com
November 28, 2023 at 1:51 PM