Somdeb Paul
somdebpaul.com
Somdeb Paul
@somdebpaul.com
Avid Reader and Biotechnologist by profession. Nucleic acid research scientist🧑‍🔬🧬 passionate about using directed evolution to solve problems in science.
@nature.com I heard the song "Hard the Hydrogel is Stuck" on this year's Nature Podcast festive spectacular 2025. I was wondering if I can find it on Apple Music so that I can add it to my Christmas playlist?
December 17, 2025 at 11:34 PM
Reposted by Somdeb Paul
Download our large database of postdoc fellowships in all fields of research.

Database freely available to all; 281 fellowships.

Download here: research.jhu.edu/rdt/funding-...
December 13, 2025 at 1:38 PM
@davidimel.com What does it take to be a tech journalist? What was your journey to becoming a host on the Waveform podcast? How do you see yourself in this field?
December 13, 2025 at 10:15 AM
Reposted by Somdeb Paul
Artificial intelligence and machine learning are being embedded in every aspect of the drug discovery and development process. Despite AI’s use at each step, the billion-dollar question is whether it can bring a larger number of novel drugs to market. cen.acs.org/physical-che... #chemsky 🧪
How AI is taking over every step of drug discovery
Academic scientists and pharmaceutical companies alike are embracing artificial intelligence, even as questions linger about its value
cen.acs.org
October 14, 2025 at 1:37 PM
Reposted by Somdeb Paul
@davidimel.com What is your opinion of the Ladybird browser? They are building an open sourced, independent browser. Is that something which is worthy of the Waveform podcast?
October 7, 2025 at 2:13 PM
Reposted by Somdeb Paul
Nature research paper: One-shot design of functional protein binders with BindCraft

go.nature.com/46bhOAv
One-shot design of functional protein binders with BindCraft - Nature
BindCraft, an open-source, automated pipeline for de novo protein binder design with experimental success rates of 10–100%, leverages AlphaFold2 weights to generate binders with nanomolar affinity without the need for high-throughput screening.
go.nature.com
September 1, 2025 at 5:37 PM
Reposted by Somdeb Paul
Over time, I, like many people, entrusted my email address to companies that gave away, sold, or lost my personal information in data breaches, which led to criminals posting my email address (and millions more) on the dark web.
I Found My Email Address on the Dark Web. Here’s How I Figured Out Who Leaked It
I loved email. It was the perfect kinda-personal-but-boundary-affirming way to keep in touch. However, over time, I, like many people, entrusted my email address to companies that gave away, sold, or lost my personal information in data breaches, which led to criminals posting my email address (and millions more) on the dark web.
bit.ly
June 14, 2025 at 1:10 AM
Reposted by Somdeb Paul
At Apple's 2024 Worldwide Developer Conference, I sat in the baking sun outside the company's glass spaceship-like headquarters in Cupertino while Craig Federighi described the marvelous capabilities of Apple Intelligence.
WWDC 2025: Apple Is Years Behind Google and Microsoft in AI. How Much Does It Matter?
At Apple's 2024 Worldwide Developer Conference, I sat in the baking sun outside the company's glass spaceship-like headquarters in Cupertino while Craig Federighi described the marvelous capabilities of Apple Intelligence. He promised that your iPhone would be able to synthesize your interactions with public data to deliver practical answers to questions like “What time should I leave to pick up Julian?” Your phone would know that Julian is your nephew who is visiting you in Albuquerque on the 6:10 Delta flight, and how the current traffic affects when you should depart for the airport. These examples excited the crowd.
bit.ly
June 9, 2025 at 3:19 PM
Reposted by Somdeb Paul
Here's how to do more useful searches in Bluesky, like finding posts to or from a specific user: bsky.social/about/blog/0...
Tips and Tricks for Bluesky Search - Bluesky
Let’s dive into all the tips and tricks for advanced Bluesky search!
bsky.social
June 2, 2025 at 1:17 PM
The 3 eyed owl icon for Duolingo is gross 🤮 it gives me a weird feeling internally and makes me want to hide the app from view. Please change the app icon ASAP!!!!!!

@duolingoverde.bsky.social @duolingobrasil.com.br #duolingo
#duolingoindia
#duolingoglobal
May 30, 2025 at 4:56 PM
Reposted by Somdeb Paul
Really scary stuff. the US NSF is following the lead of Ted Cruz cancelling "questionable projects that pushed onto science neo-Marxist perspectives about enduring class struggle". I've worked with NSF for 32 years. Something is wrong. This is not what they do.🧪

www.science.org/content/arti...
In killing grants, NSF appears to follow Ted Cruz’s blueprint
Senator’s report targeted up to $2 billion for diversity, climate change, and misinformation research
www.science.org
April 25, 2025 at 12:57 AM
Reposted by Somdeb Paul
Telltale signs of chatbot use are scattered through the scholarly literature

https://go.nature.com/3YJAvqS
Science sleuths flag hundreds of papers that use AI without disclosing it
Telltale signs of chatbot use are scattered through the scholarly literature — and, in some cases, have disappeared without a trace.
go.nature.com
April 24, 2025 at 1:39 PM
Reposted by Somdeb Paul
Larger models can pull off a wider variety of feats, but the reduced footprint of smaller models makes them attractive tools. www.wired.com/story/why-re...
Small Language Models Are the New Rage, Researchers Say
Larger models can pull off a wider variety of feats, but the reduced footprint of smaller models makes them attractive tools.
www.wired.com
April 13, 2025 at 6:05 AM
Reposted by Somdeb Paul
We’re starting to be able to see larger-scale multimers of mRNA species, and it’s a whole new world to explore:
RNA Motifs Coming Into Focus
www.science.org
April 10, 2025 at 5:50 PM
Reposted by Somdeb Paul
My thoughts on the “pharmaceutical tariffs” issue, and an explanation of just what a morass it is.
Pharmaceutical Tariffs: The What and the How
www.science.org
April 9, 2025 at 4:22 PM
Reposted by Somdeb Paul
A poor working relationship with a supervisor or manager can result in lost opportunities, creating an unexplained gap in an early-career researcher’s publication record

https://go.nature.com/3EigMHP
How do I explain the publication gap I ended up with after a hostile manager?
A poor working relationship with a supervisor or manager can result in lost opportunities, creating an unexplained gap in an early-career researcher’s publication record.
go.nature.com
April 9, 2025 at 3:04 PM
Reposted by Somdeb Paul
Our current situation
April 6, 2025 at 9:36 PM
Reposted by Somdeb Paul
Let’s walk through how to recognize a seizure in a bystander or loved one, and what to do in those crucial moments after a seizure begins, with guidance from a neurologist:
Recognizing when someone is having a seizure – and how you can help during those first critical moments
What you don’t do: Don’t shout at them, don’t put things in their mouth and don’t let them get near things that are sharp or hard in case of a fall.
buff.ly
April 6, 2025 at 4:35 AM
How the wealthy can squeeze their way out of the environmental crisis!
wired.com WIRED @wired.com · Apr 5
The elective medical industry is cashing in on plastic pollution fears with a new treatment to clean blood of microplastics. But it’s an expensive service, and the evidence of harm from microplastics is still deeply uncertain.
This Startup Says It Can Clean Your Blood of Microplastics
The elective medical industry is cashing in on plastic pollution fears, but the evidence of harm from microplastics is still deeply uncertain.
www.wired.com
April 6, 2025 at 3:00 AM
Reposted by Somdeb Paul
Reposted by Somdeb Paul
Our democratically elected #paperofthemonth is an impressive work on polymer circularity. Han and coworkers designed a Polyester with Complementary Mechanical and Chemical Recyclability under Mild Conditions. #chemsky
doi.org/10.1002/anie...
Molecular Design for Dual Circularity: Polyester with Complementary Mechanical and Chemical Recyclability under Mild Conditions
A dual circularity concept was demonstrated to prevent plastic waste accumulation, where rational design paved the way. Apart from fully recovery of mechanical and thermal properties after as many as...
doi.org
February 7, 2025 at 4:40 PM
Reposted by Somdeb Paul
Strengthening our scientific community is more important than ever.

The 2025 Molecular Switches & Motors GRC brings together scientists in the areas of molecular switches & motors, DNA nanotech, emergent materials, haptics, biological motors, and more. Apply today!

www.grc.org/artificial-m...
January 30, 2025 at 11:46 PM
Reposted by Somdeb Paul
Rock and dust samples brought back from the near-Earth asteroid Bennu contain organic matter, including amino acids and all five DNA and RNA nucleobases, according to two papers in Nature Astronomy and Nature.
https://go.nature.com/40SlwfF
https://go.nature.com/3CC6ZLO
🔭 🧪
January 30, 2025 at 5:53 PM
Reposted by Somdeb Paul
Together with the MAGA anti-immigration messaging this going to have worse consequences on the level of recruiting international talent for science and research in the USA than we've already seen during Trump's 1st term 🧪🎓
January 23, 2025 at 8:33 AM