banner
simon-renders-md.bsky.social
@simon-renders-md.bsky.social
Pinned
A great ride with amazing @verat-h.bsky.social and @jasperpanten.bsky.social with Andreas Trumpp @dkfz.bsky.social - we hope this leads to more elegant biology and clinical translation in PDAC and beyond. www.nature.com/articles/s41...

Perspective @nature.com
www.nature.com/articles/d41...
Reposted
New research by the @ninacabezas.bsky.social lab & collaborators from @uniklinik-fr.bsky.social.

A vitamin A metabolite may offer a targeted therapeutic strategy for heart attack patients by regulating HSCs to minimize excessive inflammation and preserve long-term heart function.
Healing a broken heart
A vitamin A metabolite, 4-oxo-retinoic acid, can regulate the activity of hematopoietic stem cells and thereby reduce inflammation after a heart attack, ultimately improving heart function in the long...
www.ie-freiburg.mpg.de
April 2, 2025 at 9:50 AM
Reposted
A bit of the backstory to our recent Nature paper. Find out more in the „behind the paper“ with @hi_stem_lab @dkfz.bsky.social
Thanks again to all the co-authors specifically @simon-renders-md.bsky.social and Jasper Panten

communities.springernature.com/posts/chasin...
Chasing Ghosts – The Quest to Capture Neurons in Pancreatic Cancer
Neurons infiltrate pancreatic tumors, yet their molecular identity has remained elusive . How do these nerves shape the tumor microenvironment and influence cancer progression? Using Trace-n-Seq, we m...
communities.springernature.com
February 21, 2025 at 8:50 PM
Reposted
A technology to identify and profile mouse neurons that connect the spinal cord to pancreatic cancer might improve treatment of this disease

https://go.nature.com/40ZoYUK
Pinpointing neurons that hinder cancer treatment
Method to identify neurons associated with pancreatic cancer.
go.nature.com
February 19, 2025 at 2:46 PM
Reposted
oops, actually three cancer neuroscience papers, number three, very cool combination of retrograde tracing and single cell analyses: www.nature.com/articles/s41...
Characterization of single neurons reprogrammed by pancreatic cancer - Nature
Nature - Characterization of single neurons reprogrammed by pancreatic cancer
www.nature.com
February 20, 2025 at 8:31 AM
Also getting highlighted by @erictopol.bsky.social is clearly a bucket list achievement. ☺️☺️☺️
February 18, 2025 at 5:08 PM
A great ride with amazing @verat-h.bsky.social and @jasperpanten.bsky.social with Andreas Trumpp @dkfz.bsky.social - we hope this leads to more elegant biology and clinical translation in PDAC and beyond. www.nature.com/articles/s41...

Perspective @nature.com
www.nature.com/articles/d41...
February 18, 2025 at 5:03 PM
Reposted
Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature.
We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social
www.nature.com/articles/s41...
February 18, 2025 at 9:37 AM
Reposted
Today @nature.com on how pancreatic cancer can hijack our nervous system and how denervation may be therapeutic
www.nature.com/articles/s41...
Characterization of single neurons reprogrammed by pancreatic cancer - Nature
Nature - Characterization of single neurons reprogrammed by pancreatic cancer
www.nature.com
February 18, 2025 at 12:40 AM