Noam Shemesh
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shemesh-lab.bsky.social
Noam Shemesh
@shemesh-lab.bsky.social
Reposted by Noam Shemesh
Great coverage by @thetransmissions.bsky.social of our latest preprint: adding new evidence (and a hint of controversy 🙂) to the E/I imbalance debate in autism
👇👇
www.thetransmitter.org/spectrum/ram...
Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.
www.thetransmitter.org
November 4, 2025 at 10:59 AM
Reposted by Noam Shemesh
Unlike the heart attack of getting a “Decision” email, it’s such a good feeling to get a “Your review is ready” email from qed :)
October 21, 2025 at 4:40 PM
Reposted by Noam Shemesh
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
Reposted by Noam Shemesh
Tried this on a very technical fMRI manuscript with neuroscience applications. It warned me that neuroses outside its core expertise, but then proceeded to present an amazing analysis of the claims in the paper. Vastly superior to ChatGPT for example. I am impressed!
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 20, 2025 at 9:25 PM
Reposted by Noam Shemesh
The things we can do @westernu.ca thanks to platform support grant funding from @braincanada.bsky.social And #NFRF
#fluorescencefriday special. Half marmoset 🧠 cleared and stained using SHIELD and imaged by lightsheet microscopy. Courtesy of Jesleen Saini @shahrzadbahrampour.bsky.social and @stefan-everling.bsky.social
October 3, 2025 at 10:13 PM
Reposted by Noam Shemesh
Even though the controversial DIANA method didn’t pan out, neuroimaging researchers still hold out hope to one day measure neuronal activity using fMRI.

By @callimcflurry.bsky.social

www.thetransmitter.org/retraction/a...
Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
www.thetransmitter.org
September 26, 2025 at 8:05 PM
Reposted by Noam Shemesh
New paper in Imaging Neuroscience by Roza G. Bayrak, Catie Chang, et al:

DeepPhysioRecon: Tracing peripheral physiology in low frequency fMRI dynamics

doi.org/10.1162/IMAG...
September 26, 2025 at 8:40 AM
Reposted by Noam Shemesh
A new open source nonsurgical head restraint for awake mouse fMRI from our lab led by Sam Laxer. TL;DR Scanning about 25% longer than with a surgically implanted head post, combined with some training gives good results. Happy mice = happy rsfmri networks. direct.mit.edu/imag/article...
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
Abstract. Mouse functional magnetic resonance imaging (fMRI) studies contribute significantly to basic fundamental and translational neuroscience research. Performing fMRI in awake mice could facilita...
direct.mit.edu
September 22, 2025 at 9:13 PM
Reposted by Noam Shemesh
Science is self correcting. Finally!
Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
www.thetransmitter.org
September 25, 2025 at 6:51 PM
Reposted by Noam Shemesh
A method for capturing neuronal activity using fMRI excited the neuroimaging field but couldn’t be replicated. Today, the authors of the original paper retracted their work.

By @callimcflurry.bsky.social

#neuroskyence

www.thetransmitter.org/retraction/a...
Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
www.thetransmitter.org
September 25, 2025 at 6:10 PM
An important retraction of the DIANA paper. Scientific progress is often made by correcting prior efforts, and here the community played its part efficiently. While this particular form of mapping neural activity was unsuccessful, the search continues!

www.thetransmitter.org/retraction/a...
Authors retract Science paper on controversial fMRI method
Several MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted this month.
www.thetransmitter.org
September 25, 2025 at 7:52 PM
Reposted by Noam Shemesh
New paper in Imaging Neuroscience by Marie E. Galteau, Joanes Grandjean, et al:

Activation mapping in multi-center retrospective rat sensory-evoked functional MRI datasets using a unified pipeline

doi.org/10.1162/IMAG...
September 24, 2025 at 8:19 AM
direct.mit.edu/imag/article...

NEW PAPER!
After many years in the making... we present evidence that BOLD-fMRI can detect push-pull interactions in subcortical areas. Congrats to Frederico Severo and Mafalda Valente!
Functional MRI reveals subcortical auditory push-pull interactions requiring intercollicular integrity
Abstract. The role of subcortical structures in binaural integration is of great interest for auditory processing. The inferior colliculus (IC) is the main auditory midbrain center where ascending and...
direct.mit.edu
September 6, 2025 at 5:25 PM
Reposted by Noam Shemesh
More fields need to do this.
On this day 2y ago we announced our move away from the huge profits that NeuroImage makes for Elsevier.

Things at Imaging Neuroscience have progressed fantastically thanks to the support for this move by the brain imaging community and @mitpress.bsky.social. 565 papers published already!
June 7, 2025 at 11:51 AM
Another new paper from the Lab, with a multimodal fMRI / CBF / cFOS approach in an animal model of Parkinson's Disease!

Congrats @ruxandalungu.bsky.social @ciscaff.bsky.social, Sara Monteiro and our great collaborator Tiago Monteiro!

journals.sagepub.com/doi/10.1177/...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
May 8, 2025 at 3:26 PM
Reposted by Noam Shemesh
🧠👁️A SC push-pull interaction during the dynamic vision mode, revealed with fMRI and brain lesions, challenges the notion that intertectal connections solely serve as reciprocal inhibitory mechanisms for avoiding visual blur during saccades. @shemesh-lab.bsky.social

doi.org/10.1038/s420...
Evidence for a push-pull interaction between superior colliculi in monocular dynamic vision mode - Communications Biology
A SC push-pull interaction during the dynamic vision mode, revealed with functional MRI and brain lesions, challenges the notion that intertectal connections solely serve as reciprocal inhibitory mech...
doi.org
May 1, 2025 at 6:11 PM
new paper from the Lab, harnessing fMRI and lesions to reveal some interesting "push-pull" interactions in Superior Colliculus! Check it out here
www.nature.com/articles/s42...
Evidence for a push-pull interaction between superior colliculi in monocular dynamic vision mode - Communications Biology
A SC push-pull interaction during the dynamic vision mode, revealed with functional MRI and brain lesions, challenges the notion that intertectal connections solely serve as reciprocal inhibitory mech...
www.nature.com
April 24, 2025 at 10:33 AM
Reposted by Noam Shemesh
1/ Six years in the making! Our preprint on SORDINO fMRI is out. We're sharing the raw data and sequence to facilitate brain-wide mapping in awake, behaving rodents. If this could be useful to your colleagues and friends, please help spread the word!
www.biorxiv.org/content/10.1...
March 17, 2025 at 3:46 PM
AMAZING opportunity, don't miss it!
If you would like to postdoc in ultra high field MRI (3T+7T human, 9.4T+15.2T marmoset and mouse) in a well funded lab with tons of great neuroscience collaborations, drop me a DM soon.
Western Postdoctoral Fellowship Program
Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.
uwo.ca
March 6, 2025 at 6:38 PM
Reposted by Noam Shemesh
It’s the honour of a lifetime to be elected as ESMI's President-elect. Thank you for your faith in me. I will work hard to promote the values of the Society to a broad audience and be a strong advocate for the discoveries you have made in molecular imaging. 🙏🏻

www.kcl.ac.uk/news/profess...
Professor Tim Witney elected Vice President of ESMI
Professor Tim Witney, Wellcome Trust Senior Research Fellow and Professor of Molecular Imaging at the School of Biomedical Engineering & Imaging Sciences, has been elected the Vice President of the Eu...
www.kcl.ac.uk
March 5, 2025 at 12:28 PM
check out our new preprint! Together with Joana Carvalho and Koen Hak (and co-authors) we developed an ultrafast fMRI with layer resolution, and show how feedback/feedforward signals can be mapped from a layer connective field model
www.biorxiv.org/content/10.1...

MORE in a few weeks!
Layer connective fields from ultrafast resting-state fMRI differentiate feedforward from feedback signaling
Deciphering the directionality of information flow in cortical circuits is essential for understanding brain dynamics, learning, and neuroplasticity after injury. However, current non-invasive methods...
www.biorxiv.org
March 1, 2025 at 11:55 AM
Reposted by Noam Shemesh
🔍 New must-see resource! 🧠
--> Reproducible Brain Charts – an open-data tool for mapping brain development & mental health

www.biorxiv.org/content/10.1...

👏 Kudos to @ted-satterthwaite.bsky.social and Michael Milham @childmindinstitute.bsky.social for leading this effort!
February 27, 2025 at 1:30 PM