Sezin Aday Aydin, Ph.D.
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sezinaday.bsky.social
Sezin Aday Aydin, Ph.D.
@sezinaday.bsky.social
Bioengineer, tech transfer enthusiast. 👩‍🔬🔬
PM @Penn | Former postdoc @harvardmed @MIT | PhD @MITPortugal ♀️🏳️‍🌈✊🏿✊🏾✊🏽✊🏼✊🏻
Reposted by Sezin Aday Aydin, Ph.D.
A study in Nature Neuroscience shows that brain inflammation in COVID-19 correlates with viral load, systemic inflammation and virus-sensing pattern recognition receptors. Microglial dysfunction occurs at sites of vascular inflammation with myelin injury and synapse loss. 🧪
Microglia dysfunction, neurovascular inflammation and focal neuropathologies are linked to IL-1- and IL-6-related systemic inflammation in COVID-19 - Nature Neuroscience
The authors show that brain inflammation in COVID-19 correlates with viral load, systemic inflammation and virus-sensing pattern recognition receptors. Microglial dysfunction occurs at sites of vascular inflammation with myelin injury and synapse loss.
go.nature.com
March 22, 2025 at 1:26 AM
Reposted by Sezin Aday Aydin, Ph.D.
Rust et al. examine the structure of the blood–brain barrier, highlighting changes with aging, neurodegeneration, and injury. They discuss how BBB disruption can accelerate disease progression, and review emerging drug delivery strategies. tinyurl.com/ykrwr7wn
March 16, 2025 at 12:19 PM
Reposted by Sezin Aday Aydin, Ph.D.
Research links TDP-43 loss in blood vessels to neurodegeneration
New #research finds that endothelial TDP-43 loss disrupts the blood-brain barrier, linking vascular dysfunction to #Alzheimers, ALS and FTD.
#Longevity #AgingResearch #Neurodegeneration #BrainHealth
Research links TDP-43 loss in blood vessels to neurodegeneration
New research finds that endothelial TDP-43 loss disrupts the blood-brain barrier, linking vascular dysfunction to Alzheimer’s, ALS and FTD.
longevity.technology
March 17, 2025 at 8:12 PM