Sebastian Hofer
@sebastianhofer.bsky.social
All organisms age. Why?
Always curious, especially about metabolism, autophagy, aging, and the immune system. Postdoc @mdc-berlin.bsky.social
Links and research: https://linktr.ee/sebastianhofer
🇦🇹->🇫🇷->🇩🇪
Always curious, especially about metabolism, autophagy, aging, and the immune system. Postdoc @mdc-berlin.bsky.social
Links and research: https://linktr.ee/sebastianhofer
🇦🇹->🇫🇷->🇩🇪
Reposted by Sebastian Hofer
📢 Interested in #immunology research? Join our “Afternoon for Immunology”! Scientists at all career stages will present their research.
📍 September 4, 15:00-18:00
Robert-Rössle-Str 10
Dendrit 2/3
13125 Berlin
🔗 www.mdc-berlin.de/Afternoonfor...
📍 September 4, 15:00-18:00
Robert-Rössle-Str 10
Dendrit 2/3
13125 Berlin
🔗 www.mdc-berlin.de/Afternoonfor...
August 28, 2025 at 3:56 PM
📢 Interested in #immunology research? Join our “Afternoon for Immunology”! Scientists at all career stages will present their research.
📍 September 4, 15:00-18:00
Robert-Rössle-Str 10
Dendrit 2/3
13125 Berlin
🔗 www.mdc-berlin.de/Afternoonfor...
📍 September 4, 15:00-18:00
Robert-Rössle-Str 10
Dendrit 2/3
13125 Berlin
🔗 www.mdc-berlin.de/Afternoonfor...
🥁 Extremely happy to share that my first review as corresponding author for a major outlet is now out in
@nataging.nature.com: “Understanding and improving vaccine efficacy in older adults”.
👉 nature.com/articles/s43...
(1/5)
@nataging.nature.com: “Understanding and improving vaccine efficacy in older adults”.
👉 nature.com/articles/s43...
(1/5)
August 16, 2025 at 7:08 AM
🥁 Extremely happy to share that my first review as corresponding author for a major outlet is now out in
@nataging.nature.com: “Understanding and improving vaccine efficacy in older adults”.
👉 nature.com/articles/s43...
(1/5)
@nataging.nature.com: “Understanding and improving vaccine efficacy in older adults”.
👉 nature.com/articles/s43...
(1/5)
Reposted by Sebastian Hofer
Can fasting boost vaccine protection as we age?
A trial at #mdcBerlin is testing intermittent fasting before flu & COVID shots to strengthen immunity in adults 60+.
Aging weakens the immune system, but fasting may restore autophagy and improve vaccine responses.
🔗 www.mdc-berlin.de/news/news/bo...
A trial at #mdcBerlin is testing intermittent fasting before flu & COVID shots to strengthen immunity in adults 60+.
Aging weakens the immune system, but fasting may restore autophagy and improve vaccine responses.
🔗 www.mdc-berlin.de/news/news/bo...
August 14, 2025 at 3:54 PM
Can fasting boost vaccine protection as we age?
A trial at #mdcBerlin is testing intermittent fasting before flu & COVID shots to strengthen immunity in adults 60+.
Aging weakens the immune system, but fasting may restore autophagy and improve vaccine responses.
🔗 www.mdc-berlin.de/news/news/bo...
A trial at #mdcBerlin is testing intermittent fasting before flu & COVID shots to strengthen immunity in adults 60+.
Aging weakens the immune system, but fasting may restore autophagy and improve vaccine responses.
🔗 www.mdc-berlin.de/news/news/bo...
Good news: New antibiotic that kills drug-resistant bacteria discovered in technician’s garden www.nature.com/articles/d41...
New antibiotic that kills drug-resistant bacteria discovered in technician’s garden
The molecule targets bacteria in a way that other drugs don’t.
www.nature.com
April 1, 2025 at 2:29 PM
Good news: New antibiotic that kills drug-resistant bacteria discovered in technician’s garden www.nature.com/articles/d41...
Submissions are still open for presenting at the upcoming Gordon Research Seminar (GRS) on Polyamines in July. PhD students and postdocs can submit their abstracts until mid-April. Join this incredible biannual event with the fantastic polyamine research community! 💫
www.grc.org/polyamines-g...
www.grc.org/polyamines-g...
March 31, 2025 at 7:40 PM
Submissions are still open for presenting at the upcoming Gordon Research Seminar (GRS) on Polyamines in July. PhD students and postdocs can submit their abstracts until mid-April. Join this incredible biannual event with the fantastic polyamine research community! 💫
www.grc.org/polyamines-g...
www.grc.org/polyamines-g...
Reposted by Sebastian Hofer
This is how you write editorials: you own what you say, and you put your name, even if it's "by the entire team". Someone needs to take responsibility.
Kudos to Nonia and the journal.
#SignYourEditorials
Kudos to Nonia and the journal.
#SignYourEditorials
March 26, 2025 at 6:55 PM
This is how you write editorials: you own what you say, and you put your name, even if it's "by the entire team". Someone needs to take responsibility.
Kudos to Nonia and the journal.
#SignYourEditorials
Kudos to Nonia and the journal.
#SignYourEditorials
#Hiring: 2 PhD Opportunities in Berlin!
Join the Simon group at MDC Berlin (lnkd.in/dVJsA6RU)! We’re looking for 2 candidates to work on exciting projects exploring autophagy & aging in the immune system. These fully funded 3-year positions start Sept 25 and will be part of the MSCA UNION network.
Join the Simon group at MDC Berlin (lnkd.in/dVJsA6RU)! We’re looking for 2 candidates to work on exciting projects exploring autophagy & aging in the immune system. These fully funded 3-year positions start Sept 25 and will be part of the MSCA UNION network.
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
March 14, 2025 at 1:46 PM
#Hiring: 2 PhD Opportunities in Berlin!
Join the Simon group at MDC Berlin (lnkd.in/dVJsA6RU)! We’re looking for 2 candidates to work on exciting projects exploring autophagy & aging in the immune system. These fully funded 3-year positions start Sept 25 and will be part of the MSCA UNION network.
Join the Simon group at MDC Berlin (lnkd.in/dVJsA6RU)! We’re looking for 2 candidates to work on exciting projects exploring autophagy & aging in the immune system. These fully funded 3-year positions start Sept 25 and will be part of the MSCA UNION network.
Reposted by Sebastian Hofer
I am overjoyed to present our latest paper on Autophagy in CD8 Tcells!
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.
I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.
I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells - Nature Immunology
Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in ...
www.nature.com
March 1, 2025 at 11:18 AM
I am overjoyed to present our latest paper on Autophagy in CD8 Tcells!
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.
I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
www.nature.com/articles/s41...
It was, as all ‘sciencing’ is, a huge team effort.
I will try to do it some justice in the following thread 😊 1/n
@cantrell-lab.bsky.social @immpres.bsky.social @ajmhowden.bsky.social
Super cool story about macrophages distinguishing dead and live bacteria based on metabolic cues and how they are utilised differently to shape immunomeabolism
Spectacular work by the Johan Garaude Lab @Inserm.fr on the recycling of metabolites from phagocytosed bacteria by macrophages, and its impact on tuning the immune response by digesting live vs. dead bacteria.
presse.inserm.fr/en/les-macro...
presse.inserm.fr/en/les-macro...
Macrophages: The immune system foodies - Inserm Newsroom
Macrophages, key cells of the immune system, play a central role in cleaning the body by ingesting and destroying pathogens (bacteria, viruses, etc.) and damaged cells. Scientists from Inserm, CNRS an...
presse.inserm.fr
February 26, 2025 at 5:33 PM
Super cool story about macrophages distinguishing dead and live bacteria based on metabolic cues and how they are utilised differently to shape immunomeabolism
Reposted by Sebastian Hofer
Phase separation of p62: roles and regulations in autophagy
Phase separation of p62: roles and regulations in autophagy
The phase separation of the cargo receptor sequestome-1/p62 (SQSTM1/p62) is a critical mechanism for assembling signaling complexes in autophagy. During this process, p62 undergoes phase separation upon binding to polyubiquitin chains, concentrating…
dlvr.it
February 26, 2025 at 4:44 PM
Phase separation of p62: roles and regulations in autophagy
Reposted by Sebastian Hofer
Nature research paper: IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control
https://go.nature.com/4guUvnp
https://go.nature.com/4guUvnp
IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control - Nature
IL-27 promotes tumour control by preventing dysfunction and enhancing cytotoxicity of tumour-specific CD8+ T cells.
go.nature.com
February 5, 2025 at 8:47 PM
Nature research paper: IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control
https://go.nature.com/4guUvnp
https://go.nature.com/4guUvnp
Reposted by Sebastian Hofer
Exciting news! 🌱 With march I will join the BOKU University in Vienna as a tenure-track assistant!
My group will investigate how plants integrate complex environmental stresses to induce #autophagy.
www.thegrosslab.com
@bokuvienna.bsky.social
#plantscience #biochemistry #cellbiology #academicsky
My group will investigate how plants integrate complex environmental stresses to induce #autophagy.
www.thegrosslab.com
@bokuvienna.bsky.social
#plantscience #biochemistry #cellbiology #academicsky
Gross Autophagy Lab
www.thegrosslab.com
February 4, 2025 at 8:48 AM
Exciting news! 🌱 With march I will join the BOKU University in Vienna as a tenure-track assistant!
My group will investigate how plants integrate complex environmental stresses to induce #autophagy.
www.thegrosslab.com
@bokuvienna.bsky.social
#plantscience #biochemistry #cellbiology #academicsky
My group will investigate how plants integrate complex environmental stresses to induce #autophagy.
www.thegrosslab.com
@bokuvienna.bsky.social
#plantscience #biochemistry #cellbiology #academicsky
Reposted by Sebastian Hofer
We’re Hiring: 18 PhD Positions Available!
👉MENTOR is a cutting-edge multi-disciplinary training network focused on mTOR signaling
👉We aim to recruit talented doctoral candidates to contribute to groundbreaking research on mTORopathies and their therapeutic potential.
#PhDPositions #mTORResearch
👉MENTOR is a cutting-edge multi-disciplinary training network focused on mTOR signaling
👉We aim to recruit talented doctoral candidates to contribute to groundbreaking research on mTORopathies and their therapeutic potential.
#PhDPositions #mTORResearch
February 3, 2025 at 10:07 PM
We’re Hiring: 18 PhD Positions Available!
👉MENTOR is a cutting-edge multi-disciplinary training network focused on mTOR signaling
👉We aim to recruit talented doctoral candidates to contribute to groundbreaking research on mTORopathies and their therapeutic potential.
#PhDPositions #mTORResearch
👉MENTOR is a cutting-edge multi-disciplinary training network focused on mTOR signaling
👉We aim to recruit talented doctoral candidates to contribute to groundbreaking research on mTORopathies and their therapeutic potential.
#PhDPositions #mTORResearch