Sebastian Hofer
sebastianhofer.bsky.social
Sebastian Hofer
@sebastianhofer.bsky.social
All organisms age. Why?

Always curious, especially about metabolism, autophagy, aging, and the immune system. Postdoc @mdc-berlin.bsky.social

Links and research: https://linktr.ee/sebastianhofer

🇦🇹->🇫🇷->🇩🇪
For a short news piece about our review and our contributions to this interesting field:
👉 mdc-berlin.de/news/news/bo...

Teaser: We’ve just started recruiting for our trial to explore whether dietary interventions can help improve age-related vaccine inefficacy! More soon. (5/5)
Boosting vaccine efficacy as we age
Can an aging immune system be coaxed into responding to vaccination like its’ younger self? In “Nature Aging,” Sebastian Hofer, Katja Simon and colleagues discuss emerging interventions that may boost...
mdc-berlin.de
August 16, 2025 at 7:08 AM
This was a real team effort with Simon Rapp, Paul Klenerman and Katja Simon from the @mdc-berlin.bsky.social and @ox.ac.uk

The piece appears in a stellar special issue on immune aging, which brings together an excellent lineup of authors and reviews worth exploring: nature.com/articles/s43...
(4/5)
The immune system offers a window into aging - Nature Aging
The immune system permeates and regulates organs and tissues across the body, and has diverse roles beyond pathogen control, including in development, tissue homeostasis and repair. The reshaping of t...
nature.com
August 16, 2025 at 7:08 AM
While putting this together, we were struck by how little is still known in this area! In the review, we thus explore how targeting the biology of aging itself might provide more fundamental solutions to age-related declines in vaccine efficacy than technical fixes alone. (3/5)
August 16, 2025 at 7:08 AM
We outline how age-related changes in the immune system shape vaccine responses, and discuss both traditional and emerging strategies to improve protection in older adults. A key focus is the intersection of geroscience and vaccinology.

(2/5)
August 16, 2025 at 7:08 AM
Please share and spread the word to help us find great candidates! 🌍

#PhD #ScienceJobs #Immunology #Autophagy #AgingResearch #Berlin
March 14, 2025 at 1:46 PM
We seek candidates who are passionate about immunology and aging research, and who thrive in an innovative and dynamic environment at the @mdc-berlin.bsky.social

📌 Location: MDC, Berlin, Germany
📅 Start Date: September 2025
👉 Apply now: www.mdc-berlin.de/career/jobs/...
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March 14, 2025 at 1:46 PM