Sonja Schmid
@scisonja.bsky.social
Assist. Prof. @unibas.ch 🇨🇭 developing single-molecule techniques to explore the nano-dynamics of proteins&Co.
https://schmid.chemie.unibas.ch/en/
https://schmid.chemie.unibas.ch/en/
Pinned
Sonja Schmid
@scisonja.bsky.social
· Jul 31
Home | Research Group Schmid | University of Basel
schmid.chemie.unibas.ch
💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭:
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
Join us for a #postdoc through a #MarieCurie fellowship via the 2026 call. Eligible candidates are invited to reach out with a tentative project idea. Happy to support you! marie-sklodowska-curie-actions.ec.europa.eu/actions/post...?
November 11, 2025 at 9:29 AM
Join us for a #postdoc through a #MarieCurie fellowship via the 2026 call. Eligible candidates are invited to reach out with a tentative project idea. Happy to support you! marie-sklodowska-curie-actions.ec.europa.eu/actions/post...?
I recently wrote a 1page "Highlight" article for the Swiss Journal @chimiajournal.bsky.social about the #single-molecule perspective on biomolecular dynamics and experiments:
Beyond 3D Structures: New Ways to Study Biomolecular Gymnastics
www.chimia.ch/chimia/artic...
Beyond 3D Structures: New Ways to Study Biomolecular Gymnastics
www.chimia.ch/chimia/artic...
November 10, 2025 at 5:13 PM
I recently wrote a 1page "Highlight" article for the Swiss Journal @chimiajournal.bsky.social about the #single-molecule perspective on biomolecular dynamics and experiments:
Beyond 3D Structures: New Ways to Study Biomolecular Gymnastics
www.chimia.ch/chimia/artic...
Beyond 3D Structures: New Ways to Study Biomolecular Gymnastics
www.chimia.ch/chimia/artic...
Early rise for me today (3:45 😱) to get in time to our #Nanopore consortium meeting with #GiovanniMaglia & @ceesdekker.bsky.social groups at Amsterdam airport.
So curious about their newest results! 🤩
We approached in style: ✈️ flying over Dutch (modern) windmills... Beautiful – even for train fans.
So curious about their newest results! 🤩
We approached in style: ✈️ flying over Dutch (modern) windmills... Beautiful – even for train fans.
November 7, 2025 at 9:03 AM
Early rise for me today (3:45 😱) to get in time to our #Nanopore consortium meeting with #GiovanniMaglia & @ceesdekker.bsky.social groups at Amsterdam airport.
So curious about their newest results! 🤩
We approached in style: ✈️ flying over Dutch (modern) windmills... Beautiful – even for train fans.
So curious about their newest results! 🤩
We approached in style: ✈️ flying over Dutch (modern) windmills... Beautiful – even for train fans.
Single-molecule friends!
The prelim. program of next year's sm- #Gordon conference in Switzerland is online: www.grc.org/single-molec...
It'll be 3x fantastic: science, people, place in the alps ⛰️. Kevin & I hope to see you all next June:
Have a look, tell your friends, and register!
The prelim. program of next year's sm- #Gordon conference in Switzerland is online: www.grc.org/single-molec...
It'll be 3x fantastic: science, people, place in the alps ⛰️. Kevin & I hope to see you all next June:
Have a look, tell your friends, and register!
2026 Single Molecule Approaches to Biology Conference GRC
The 2026 Gordon Research Conference on Single Molecule Approaches to Biology will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.
www.grc.org
November 2, 2025 at 7:23 PM
Single-molecule friends!
The prelim. program of next year's sm- #Gordon conference in Switzerland is online: www.grc.org/single-molec...
It'll be 3x fantastic: science, people, place in the alps ⛰️. Kevin & I hope to see you all next June:
Have a look, tell your friends, and register!
The prelim. program of next year's sm- #Gordon conference in Switzerland is online: www.grc.org/single-molec...
It'll be 3x fantastic: science, people, place in the alps ⛰️. Kevin & I hope to see you all next June:
Have a look, tell your friends, and register!
"If it needs to be fast..." says this lift ad... 🤭
Have a good weekend you all!
seen at: www.srf.ch/static/cms/i...
Have a good weekend you all!
seen at: www.srf.ch/static/cms/i...
October 24, 2025 at 3:48 PM
"If it needs to be fast..." says this lift ad... 🤭
Have a good weekend you all!
seen at: www.srf.ch/static/cms/i...
Have a good weekend you all!
seen at: www.srf.ch/static/cms/i...
Reposted by Sonja Schmid
🚀 Got cool science to share?
Join the Young Scientists’ Satellite in Zürich 🇨🇭 on Feb 10, 2026 to:
*Talk about your research
*Chat about AI & science comms
*Win prizes & meet mentors
▶️ Find out more → annual-meeting.ls2.ch/2026/special...
Join the Young Scientists’ Satellite in Zürich 🇨🇭 on Feb 10, 2026 to:
*Talk about your research
*Chat about AI & science comms
*Win prizes & meet mentors
▶️ Find out more → annual-meeting.ls2.ch/2026/special...
October 16, 2025 at 12:30 PM
🚀 Got cool science to share?
Join the Young Scientists’ Satellite in Zürich 🇨🇭 on Feb 10, 2026 to:
*Talk about your research
*Chat about AI & science comms
*Win prizes & meet mentors
▶️ Find out more → annual-meeting.ls2.ch/2026/special...
Join the Young Scientists’ Satellite in Zürich 🇨🇭 on Feb 10, 2026 to:
*Talk about your research
*Chat about AI & science comms
*Win prizes & meet mentors
▶️ Find out more → annual-meeting.ls2.ch/2026/special...
Rush! The application deadline for this #PhD or #Postdoc opportunity in my group is TODAY!
#smFRET #DyeCycling #nano-photonics & Co
#smFRET #DyeCycling #nano-photonics & Co
#2: #PhD Position in Single-Molecule Biophysics using Fluorescence & DyeCycling/FRET
➤ Also for #Postdocs!
➤ Biomolecular dynamics, dynamic disorder & more
➤ with nano-photonic & fluorogenic DyeCycling/ #FRET.
⏰: submit by 30/9, 2025.
More info & online application system: tinyurl.com/y9dnb38e
➤ Also for #Postdocs!
➤ Biomolecular dynamics, dynamic disorder & more
➤ with nano-photonic & fluorogenic DyeCycling/ #FRET.
⏰: submit by 30/9, 2025.
More info & online application system: tinyurl.com/y9dnb38e
September 30, 2025 at 12:04 PM
Rush! The application deadline for this #PhD or #Postdoc opportunity in my group is TODAY!
#smFRET #DyeCycling #nano-photonics & Co
#smFRET #DyeCycling #nano-photonics & Co
#1: #PhD Position in Single-Molecule Biophysics using Nanopore Trapping:
➤ solid-state and biological #nanopores
➤ label-free protein fingerprinting, enzyme catalysis & more
⏰: submit by Sept. 20, 2025.
More info & online application system: jobs.unibas.ch/offene-stell...
➤ solid-state and biological #nanopores
➤ label-free protein fingerprinting, enzyme catalysis & more
⏰: submit by Sept. 20, 2025.
More info & online application system: jobs.unibas.ch/offene-stell...
September 16, 2025 at 12:21 PM
Great times at the Annual Event of the @nanoscience.ch:
What a place, what a crowd, what an interdisciplinarity! Fascinating...! 😀
What a place, what a crowd, what an interdisciplinarity! Fascinating...! 😀
September 11, 2025 at 1:34 PM
Great times at the Annual Event of the @nanoscience.ch:
What a place, what a crowd, what an interdisciplinarity! Fascinating...! 😀
What a place, what a crowd, what an interdisciplinarity! Fascinating...! 😀
Wow: 7 ERC-StG for @unibas!
Congrats to all recepients in- & outside #Basel!
Congrats to all recepients in- & outside #Basel!
Seven researchers from the University of Basel receive ERC Starting Grants – an exceptional result for the University of Basel. Over the next five years, they will each receive between EUR 1.5 million and EUR 2.3 million in funding.
Seven researchers from the University of Basel receive ERC Starting Grants
In the competition for highly sought-after research funding from the European Research Council, seven researchers from the University of Basel convinced the jury with their project ideas. Over the nex...
www.unibas.ch
September 4, 2025 at 7:46 PM
Wow: 7 ERC-StG for @unibas!
Congrats to all recepients in- & outside #Basel!
Congrats to all recepients in- & outside #Basel!
Reposted by Sonja Schmid
🎓 New PhD projects in #nanobiology, #nanochemistry & #nanophysics at the SNI PhD School! Apply now to join our #interdisciplinary community. 🧪
📌 Info: nanoscience.unibas.ch/en/forschung...
@unibas.ch @biozentrum.unibas.ch @eth-bsse.bsky.social
@psich.bsky.social @scisonja.bsky.social #nanoscience
📌 Info: nanoscience.unibas.ch/en/forschung...
@unibas.ch @biozentrum.unibas.ch @eth-bsse.bsky.social
@psich.bsky.social @scisonja.bsky.social #nanoscience
August 5, 2025 at 2:05 PM
🎓 New PhD projects in #nanobiology, #nanochemistry & #nanophysics at the SNI PhD School! Apply now to join our #interdisciplinary community. 🧪
📌 Info: nanoscience.unibas.ch/en/forschung...
@unibas.ch @biozentrum.unibas.ch @eth-bsse.bsky.social
@psich.bsky.social @scisonja.bsky.social #nanoscience
📌 Info: nanoscience.unibas.ch/en/forschung...
@unibas.ch @biozentrum.unibas.ch @eth-bsse.bsky.social
@psich.bsky.social @scisonja.bsky.social #nanoscience
Reposted by Sonja Schmid
A new one to me: a protein structure board game.
You can download a PDF, and print out the parts, or play online ⬇️ (Age 10+)
You can download a PDF, and print out the parts, or play online ⬇️ (Age 10+)
Play the PDB board game that explores the process of structure discovery and deposition. Then, move on to the next project...but keep an eye on the competition and try not to get scooped! #GenCon
pdb101.rcsb.org/lear...
pdb101.rcsb.org/lear...
PDB101: Learn: Other Resources: PDB50 the Game
A PDB “worker placement” board game that explores the process of structure discovery
pdb101.rcsb.org
August 2, 2025 at 6:16 PM
A new one to me: a protein structure board game.
You can download a PDF, and print out the parts, or play online ⬇️ (Age 10+)
You can download a PDF, and print out the parts, or play online ⬇️ (Age 10+)
Happy Swiss National Day! 🇨🇭 with phenomenal fireworks above the Rhine in Basel.
A day to be thankful for the unearned privilege of freedom, safety, welfare, and the stable democracy. 🤝🤝🤝
A day to be thankful for the unearned privilege of freedom, safety, welfare, and the stable democracy. 🤝🤝🤝
August 1, 2025 at 10:18 AM
Happy Swiss National Day! 🇨🇭 with phenomenal fireworks above the Rhine in Basel.
A day to be thankful for the unearned privilege of freedom, safety, welfare, and the stable democracy. 🤝🤝🤝
A day to be thankful for the unearned privilege of freedom, safety, welfare, and the stable democracy. 🤝🤝🤝
💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭:
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
Home | Research Group Schmid | University of Basel
schmid.chemie.unibas.ch
July 31, 2025 at 2:34 PM
💥 We have 3 positions open in my lab in Basel, Switzerland🇨🇭:
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
#nanopores #smFRET #biomolecular #dynamics #singleMolecules
We’re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.
Please share broadly, thank you!🤝
schmid.chemie.unibas.ch
#smFRET for the win! What can be more convincing than seeing proteins in action. (Here through DNA-labelling.)
A λ exonuclease system exhibits protospacer-adjacent motif-independent DNA-binding specificity, enabling diagnostic and imaging applications go.nature.com/3TwgkKk
rdcu.be/eynve
rdcu.be/eynve
Bacteriophage λ exonuclease and a 5′-phosphorylated DNA guide allow PAM-independent targeting of double-stranded nucleic acids - Nature Biotechnology
A λ exonuclease system exhibits protospacer-adjacent motif-independent DNA-binding specificity, enabling diagnostic and imaging applications.
go.nature.com
July 30, 2025 at 6:57 AM
#smFRET for the win! What can be more convincing than seeing proteins in action. (Here through DNA-labelling.)
Reposted by Sonja Schmid
#smFRET-lovers! Imagine, you got nice burst data with freely diffusing molecules 🙌🔬
BUT
1) Immobilization does not work🧲🤬
2) Transitions are longer than diffusion time, but shorter than frametime of your TIRF⏱️
Solution: try ABEL-trap!💕
📜bioRxiv:
doi.org/10.1101/2025.07.22.666123
BUT
1) Immobilization does not work🧲🤬
2) Transitions are longer than diffusion time, but shorter than frametime of your TIRF⏱️
Solution: try ABEL-trap!💕
📜bioRxiv:
doi.org/10.1101/2025.07.22.666123
ABEL-FRET bridges the timescale gap in single-molecule measurements of the structural dynamics in the A2A adenosine receptor
The functional complexity of G protein-coupled receptors (GPCRs) arises from their structural dynamics, which span timescales from nanoseconds to minutes. Single-molecule Förster Resonance Energy Tran...
doi.org
July 28, 2025 at 1:27 PM
#smFRET-lovers! Imagine, you got nice burst data with freely diffusing molecules 🙌🔬
BUT
1) Immobilization does not work🧲🤬
2) Transitions are longer than diffusion time, but shorter than frametime of your TIRF⏱️
Solution: try ABEL-trap!💕
📜bioRxiv:
doi.org/10.1101/2025.07.22.666123
BUT
1) Immobilization does not work🧲🤬
2) Transitions are longer than diffusion time, but shorter than frametime of your TIRF⏱️
Solution: try ABEL-trap!💕
📜bioRxiv:
doi.org/10.1101/2025.07.22.666123
Fantastic to see: 657'291 ppl saw the #EURO2025 in one of the 8 stadiums in Switzerland. #newRECORD
History made, again! Another record-breaking attendance wraps up #WEURO2025 in style 🏆🫶
#SummitOfEmotions
#SummitOfEmotions
July 27, 2025 at 7:07 PM
Fantastic to see: 657'291 ppl saw the #EURO2025 in one of the 8 stadiums in Switzerland. #newRECORD
July 27, 2025 at 6:53 PM
July 27, 2025 at 4:36 PM
Reposted by Sonja Schmid
July 27, 2025 at 1:06 PM
Reposted by Sonja Schmid
July 26, 2025 at 3:24 PM
Quick! 💣💥
Dont miss to sign up for the "Spreng-Vorlesung"
@unibas.ch
– the explosive lecture for all ages! #TheMagicOfChemistry
🌐: St. Johanns-Ring 19, 4056 #Basel
⏰: Fri or Sat Sept 12 or 13, at 11am and 2pm each (=4 shows!)
RSVP: chemie.unibas.ch/en/sprengvor...
Dont miss to sign up for the "Spreng-Vorlesung"
@unibas.ch
– the explosive lecture for all ages! #TheMagicOfChemistry
🌐: St. Johanns-Ring 19, 4056 #Basel
⏰: Fri or Sat Sept 12 or 13, at 11am and 2pm each (=4 shows!)
RSVP: chemie.unibas.ch/en/sprengvor...
July 24, 2025 at 4:39 PM
Quick! 💣💥
Dont miss to sign up for the "Spreng-Vorlesung"
@unibas.ch
– the explosive lecture for all ages! #TheMagicOfChemistry
🌐: St. Johanns-Ring 19, 4056 #Basel
⏰: Fri or Sat Sept 12 or 13, at 11am and 2pm each (=4 shows!)
RSVP: chemie.unibas.ch/en/sprengvor...
Dont miss to sign up for the "Spreng-Vorlesung"
@unibas.ch
– the explosive lecture for all ages! #TheMagicOfChemistry
🌐: St. Johanns-Ring 19, 4056 #Basel
⏰: Fri or Sat Sept 12 or 13, at 11am and 2pm each (=4 shows!)
RSVP: chemie.unibas.ch/en/sprengvor...
Good morning, with impressions from our Dept white board:
ex-cell-ent vibes, I'd say...: 🙃😅
...and we have 1-2-3 openings coming up!
ex-cell-ent vibes, I'd say...: 🙃😅
...and we have 1-2-3 openings coming up!
July 22, 2025 at 7:40 AM
Good morning, with impressions from our Dept white board:
ex-cell-ent vibes, I'd say...: 🙃😅
...and we have 1-2-3 openings coming up!
ex-cell-ent vibes, I'd say...: 🙃😅
...and we have 1-2-3 openings coming up!
Reposted by Sonja Schmid
As a man who moves around this host-city every day and lives close to the stadium, I highly recommend handing over this entire sport to women. Then it's back to the love of the game and it's fun to watch
July 20, 2025 at 5:45 PM
As a man who moves around this host-city every day and lives close to the stadium, I highly recommend handing over this entire sport to women. Then it's back to the love of the game and it's fun to watch