Principal Instigators Podcast
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scienceforhaters.bsky.social
Principal Instigators Podcast
@scienceforhaters.bsky.social
34 followers 34 following 110 posts
A science podcast for the haters. Find us on all your favorite podcast apps at https://link.chtbl.com/principalinstigators
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scienceforhaters.bsky.social
Hello everyone! You may have noticed some episodes missing from our feed in addition to the extended radio silence. We at Principal Instigators LLC can neither confirm nor deny any fair-use policy issues with our hosting platform but we are happy to announce that all our episodes are back online!
September 30, 2025 at 3:49 PM
Reposted by Principal Instigators Podcast
lastpositivist.bsky.social
My friend and colleague Remco Heesen once told me study of social epistemology of science made him "less trusting of any particular scientific paper but more impressed by science as a whole." I honestly think that's the right lesson to draw. But I think holding both attitudes doesn't come naturally.
surcomplicated.bsky.social Zoomer Antimillenarian @surcomplicated.bsky.social · Jun 24
The most important thing about science the public needs to remember is that the set of experimental and theoretical methods we refer to as "science" is the best, most reliable way of knowing we currently have.

It's rough around the edges but it works way better than anything else.
convolver.bsky.social Convolver @convolver.bsky.social · Jun 24
Watching people not realize this about his work, and then seeing it weaponized against climate policy, sent poor old Bruno Latour into a full-blown case of abyss gaze.
June 24, 2025 at 5:38 AM
scienceforhaters.bsky.social
Friendly reminder that LLMs are overhyped and can cause tremendous harms, but we shouldn't automatically trust science/tech reporting just like we shouldn't automatically trust AI companies. 🧵
junlper.beer onion person @junlper.beer · Jun 5
it’s time to replace all doctors with ai
June 6, 2025 at 7:56 PM
scienceforhaters.bsky.social
The people who die are still dead
evanurquhart.bsky.social Evan Urquhart @evanurquhart.bsky.social · May 18
Whether we elect a Democrat in 2028 does not currently matter. It could matter, but for it to matter so many things would need to have started changing before 2028.

We no longer have a functioning weather service, air traffic control, or CDC, to name just a few agencies gutted by Trump.
May 19, 2025 at 1:58 AM
scienceforhaters.bsky.social
Also we should note that we recorded this in February and things have only gotten worse since, but everything we said is still true and relevant
scienceforhaters.bsky.social Principal Instigators Podcast @scienceforhaters.bsky.social · May 17
On this quarter's episode of Principal Instigators we discuss the Trump administration's unprecedented attacks on science, which are so wide-ranging and indiscriminate that they threaten our society's basic ability to "do science" in any meaningful sense.

Happy Saturday!

pca.st/episode/5d3c...
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pca.st
May 17, 2025 at 1:51 PM
scienceforhaters.bsky.social
On this quarter's episode of Principal Instigators we discuss the Trump administration's unprecedented attacks on science, which are so wide-ranging and indiscriminate that they threaten our society's basic ability to "do science" in any meaningful sense.

Happy Saturday!

pca.st/episode/5d3c...
Web Player - Pocket Casts
Listen to your favorite podcasts online, in your browser. Discover the world's most powerful podcast player.
pca.st
May 17, 2025 at 1:04 PM
scienceforhaters.bsky.social
A special issue of a prestigious medical journal with "more research" on vaccines & autism would be an excuse for every paper in that special issue to cite all the others - and the papers in that special issue would be well-positioned to gobble up citations from future papers on this topic.
joho.bsky.social Jonathan Howard @joho.bsky.social · Mar 7
According to a former editor of JAMA, we need more studies on whether or not vaccines cause autism.

What mistakes does he make?

🧵
Interesting that some Senators criticized @DrJBhattacharya for saying he would fund research at the @NIH to show that vaccines do not cause autism. The critics argued that this was 'settled science.' Yes, there is compelling evidence against the vaccine-autism relationship. However, a large swath of the public do not believe it. Because of public skepticism, it is not settled science. There is a need for further research intentending to convince the public regarding vaccine safety. It is not good enough to say "I am a scientist at a prestigious university, and you should believe what I say because of who I am." That does not work anymore, especially after the pandemic when science's reputation took a big hit...
March 9, 2025 at 6:30 PM
scienceforhaters.bsky.social
tfw ALAB series has a faster release schedule than you
March 9, 2025 at 1:39 PM
scienceforhaters.bsky.social
24

What can you even say
January 2, 2025 at 7:47 PM
Reposted by Principal Instigators Podcast
bwestfall55.bsky.social
This is exactly why we have to keep NIH and NCI publicly funded research. A cancer cure will cost them billions. Why would they do that? Republicans always cut research budgets and years of progress are lost. Many stem cell biologists left the USA when GW Bush severely limited cell access. Morons!
therealjackhopkins.bsky.social Jack Hopkins-The Original @therealjackhopkins.bsky.social · Dec 18
This article highlights why more “crazy motherfuckers”are likely going to kill more extremely wealthy, “heartless, motherfuckers.”

Society has reached the tipping point on inequities. Especially those leaving the masses to suffer and die.

www.cnbc.com/2018/04/11/g...
Goldman Sachs asks in biotech research report: 'Is curing patients a sustainable business model?'
Goldman Sachs warns sales from the most successful disease treatments are difficult to maintain.
www.cnbc.com
December 18, 2024 at 4:56 PM
Reposted by Principal Instigators Podcast
polychromie.didnotaskfor.skin
Listen to the @scienceforhaters.bsky.social podcast for more on this nightmare of a human
junlper.beer onion person @junlper.beer · Dec 10
what can you even say about this
December 11, 2024 at 3:54 AM
scienceforhaters.bsky.social
Scheduling a recording session this week like
Screencapture of the Well There's Your Problem podcast 9/11 episode paused at the exact moment Rocz learns RBG has died
November 4, 2024 at 6:52 PM
scienceforhaters.bsky.social
If we ever end up on one of these lists something has going horribly wrong
www.vulture.com/article/new-...
The Best Podcasts of 2024 (So Far)
Including a look into the checkered history of the New York Police Department and a tech podcast with an alt-weekly bent.
www.vulture.com
October 10, 2024 at 5:57 PM
Reposted by Principal Instigators Podcast
scienceforhaters.bsky.social
On Apple Podcasts:
podcasts.apple.com/us/podcast/i...
Introductory Statistics for Unwashed Rationalists
What happens when you combine internet libertarians’ favorite woman, questionably-supported statistical analyses of human sexuality, and show tunes written by g
podcasts.apple.com
September 28, 2024 at 5:57 AM
Reposted by Principal Instigators Podcast
scienceforhaters.bsky.social
On Pocket Casts:
pca.st/episode/fe27...
Introductory Statistics for Unwashed Rationalists - Principal Instigators
A science podcast for the haters. https://bsky.app/profile/scienceforhaters.bsky.social
pca.st
September 28, 2024 at 5:56 AM
Reposted by Principal Instigators Podcast
scienceforhaters.bsky.social
Today on Principal Instigators we're discussing Mark Andreesen's favorite amateur sexologist and data science enthusiast. Curiosity, statistical understanding, and showers not guaranteed.

CW, topics include sex, sexual assault, and transphobia

Listen on Spotify:
open.spotify.com/episode/4qa7...
Introductory Statistics for Unwashed Rationalists
Episode · Principal Instigators · What happens when you combine internet libertarians’ favorite woman, questionably-supported statistical analyses of human sexuality, and show tunes written by guys fr...
open.spotify.com
September 28, 2024 at 5:55 AM
scienceforhaters.bsky.social
Today on Principal Instigators we're discussing Mark Andreesen's favorite amateur sexologist and data science enthusiast. Curiosity, statistical understanding, and showers not guaranteed.

CW, topics include sex, sexual assault, and transphobia

Listen on Spotify:
open.spotify.com/episode/4qa7...
Introductory Statistics for Unwashed Rationalists
Episode · Principal Instigators · What happens when you combine internet libertarians’ favorite woman, questionably-supported statistical analyses of human sexuality, and show tunes written by guys fr...
open.spotify.com
September 28, 2024 at 5:55 AM
scienceforhaters.bsky.social
Great news for all you nerdy, horny gremlins: our next episode (filename: statistexxx.mp3) is coming out soon & it's >2 hours long 🍆🔢🍑💻🌭📊🌮
September 27, 2024 at 8:30 PM
scienceforhaters.bsky.social
If/when Well There's Your Problem does a climate change episode they should have us as guests
July 26, 2024 at 6:35 PM
Reposted by Principal Instigators Podcast
edburmila.bsky.social
It was a real mistake to release the word “priors” into general circulation. It created an entirely new Guy and made several extant classes of Guy worse.
July 12, 2024 at 1:26 PM
scienceforhaters.bsky.social
Congratulations to @linden.bsky.social, our grand prize winner who gets all four prints!!
scienceforhaters.bsky.social Principal Instigators Podcast @scienceforhaters.bsky.social · Jun 19
We’re thrilled to announce our first-ever giveaway - for a series of lino prints with our podcast logo, designed / drawn / carved / printed by hand by one of the cohosts of Principal Instigators.
Lino cut #1: Our podcast logo (a chemistry flask containing a burning coffin, emblazoned with the word “science”) sitting on a table. The opening of the flask is giving off a golden yellow halo of light. The image is printed with black ink on off-white paper, with the exception of the flames, in red ink. Lino cut #2: The chemistry flask from our podcast logo, inverted, flying through the black sky as a hot air balloon. It is powered by the flames from a coffin that is on fire, emblazoned with the word “science.” The image is printed with black ink on off-white paper, with the exception of the flames, in red ink. Lino cut #3: The chemistry flask from our podcast logo, descending into the flames of hell, powered by its wings which are a mix of an angel’s bird wings (feathers) and a demon’s bat wings (anatomical structure). The image is printed with black ink on off-white paper, with the exception of the flames, in red ink. Lino cut #4: Our podcast logo (a chemistry flask containing a burning coffin) reimagined as Baba Yaga’s house, complete with chicken legs. The logo is wandering away from dark woods full of pine trees. The image is printed with black ink on off-white paper, with the exception of the flames, in red ink.
June 27, 2024 at 6:13 PM
Reposted by Principal Instigators Podcast
polychromie.didnotaskfor.skin
I know what this is about and I am ready to inflict psychic damage on so many of my friends when it's released!!!
scienceforhaters.bsky.social Principal Instigators Podcast @scienceforhaters.bsky.social · Jun 22
Our next episode is gonna be even more Principal Instigators than all previous episodes. I hope you sickos are ready to learn the difference between confidence intervals vs. prediction intervals in the context of sex positions other than missionary.
June 22, 2024 at 2:28 PM
scienceforhaters.bsky.social
*googling "hangover cure for 4 hour podcast recording session"
June 22, 2024 at 2:32 PM
scienceforhaters.bsky.social
Our next episode is gonna be even more Principal Instigators than all previous episodes. I hope you sickos are ready to learn the difference between confidence intervals vs. prediction intervals in the context of sex positions other than missionary.
June 22, 2024 at 5:19 AM
Reposted by Principal Instigators Podcast
polychromie.didnotaskfor.skin
If you're not listening to PI it's time to start!
scienceforhaters.bsky.social Principal Instigators Podcast @scienceforhaters.bsky.social · Jun 19
We’re thrilled to announce our first-ever giveaway - for a series of lino prints with our podcast logo, designed / drawn / carved / printed by hand by one of the cohosts of Principal Instigators.
Lino cut #1: Our podcast logo (a chemistry flask containing a burning coffin, emblazoned with the word “science”) sitting on a table. The opening of the flask is giving off a golden yellow halo of light. The image is printed with black ink on off-white paper, with the exception of the flames, in red ink. Lino cut #2: The chemistry flask from our podcast logo, inverted, flying through the black sky as a hot air balloon. It is powered by the flames from a coffin that is on fire, emblazoned with the word “science.” The image is printed with black ink on off-white paper, with the exception of the flames, in red ink. Lino cut #3: The chemistry flask from our podcast logo, descending into the flames of hell, powered by its wings which are a mix of an angel’s bird wings (feathers) and a demon’s bat wings (anatomical structure). The image is printed with black ink on off-white paper, with the exception of the flames, in red ink. Lino cut #4: Our podcast logo (a chemistry flask containing a burning coffin) reimagined as Baba Yaga’s house, complete with chicken legs. The logo is wandering away from dark woods full of pine trees. The image is printed with black ink on off-white paper, with the exception of the flames, in red ink.
June 19, 2024 at 5:43 PM