Sasha Meek
@sasmeek.bsky.social
Big fan of exocytosis, evolutionary cell biology, in situ imaging! Combining yeasts from the snow with really nice microscopes. 🇿🇦🇪🇸 PhD student in the Biophysics in Cell Biology group @gallegolab.bsky.social 🌍 www.gallegolab.org
Reposted by Sasha Meek
Preprint drop! 🚨 Rhobin-tag your proteins and watch Saci glow at high temps! 🔥 Bright, photostable, live-cell imaging made possible with JF dyes. Huge thanks to @samjlord.bsky.social @acharlesorszag.bsky.social @mullinslab.bsky.social and Bo Huang lab at UCSF.😊
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy
De novo protein design has emerged as a powerful strategy with the promise to create new tools. The practical performance of designed fluorophore binders, however, has remained far from meeting fluore...
www.biorxiv.org
June 25, 2025 at 5:57 PM
Preprint drop! 🚨 Rhobin-tag your proteins and watch Saci glow at high temps! 🔥 Bright, photostable, live-cell imaging made possible with JF dyes. Huge thanks to @samjlord.bsky.social @acharlesorszag.bsky.social @mullinslab.bsky.social and Bo Huang lab at UCSF.😊
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Sasha Meek
#membrane seminars are back this THURSDAY for a super session with @dr-downes.bsky.social from the @giuliazanetti.bsky.social lab and Xin Zhou from the Ikonen lab! @felixmendu.bsky.social @ishier.bsky.social
December 3, 2025 at 11:20 AM
#membrane seminars are back this THURSDAY for a super session with @dr-downes.bsky.social from the @giuliazanetti.bsky.social lab and Xin Zhou from the Ikonen lab! @felixmendu.bsky.social @ishier.bsky.social
Reposted by Sasha Meek
Another year in OpenPRBB, always so nice to talk about science and show our lab 🥹🧑🔬 #openprbb2025
October 8, 2025 at 4:53 PM
Another year in OpenPRBB, always so nice to talk about science and show our lab 🥹🧑🔬 #openprbb2025
Reposted by Sasha Meek
Please share🙌🤗
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
www.upf.edu
April 2, 2025 at 12:49 PM
Please share🙌🤗
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
We just opened a PhD position to investigate biophysics in eukaryotes that grow in the cryosphere (glaciers, snow, Mars....)! If you like advanced imaging, evolution and quantitative biology, apply!! we are looking for you! More details here👇
www.upf.edu/documents/28...
Incredible experience working with such a great team of researchers!! Check out our preprint on the continuum architecture of exocytosis.
Interested in imaging protein suprastructures and membranes dynamics in situ? You also happen to be preoccupied by the exocyst? Read our latest preprint where we time-resolved the choreography of a flexible exocyst higher-order structure and the vesicle in exocytosis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Continuum architecture dynamics of vesicle tethering in exocytosis
Essential for eukaryotic organisms, multiple copies of the exocyst complex tether each secretory vesicle to the plasma membrane (PM) in constitutive exocytosis. The exocyst higher-order structure (ExH...
www.biorxiv.org
February 12, 2025 at 11:47 AM
Incredible experience working with such a great team of researchers!! Check out our preprint on the continuum architecture of exocytosis.
Reposted by Sasha Meek
Nice preprint from @gallegolab.bsky.social!
Bridging static structures of exocyst with dynamic function provides really interesting flexible, ring-shaped higher-order exocyst structure (ExHOS).
Continuum architecture dynamics of vesicle tethering in exocytosis
www.biorxiv.org/content/10.1...
Bridging static structures of exocyst with dynamic function provides really interesting flexible, ring-shaped higher-order exocyst structure (ExHOS).
Continuum architecture dynamics of vesicle tethering in exocytosis
www.biorxiv.org/content/10.1...
February 6, 2025 at 1:28 PM
Nice preprint from @gallegolab.bsky.social!
Bridging static structures of exocyst with dynamic function provides really interesting flexible, ring-shaped higher-order exocyst structure (ExHOS).
Continuum architecture dynamics of vesicle tethering in exocytosis
www.biorxiv.org/content/10.1...
Bridging static structures of exocyst with dynamic function provides really interesting flexible, ring-shaped higher-order exocyst structure (ExHOS).
Continuum architecture dynamics of vesicle tethering in exocytosis
www.biorxiv.org/content/10.1...