Arghya Bhowmick
@arghya93.bsky.social
Postdoc in the Department of Cellular and Molecular Pharmacology @ University of California, San Francisco
Former Graduate student in Department of Biological Sciences
@ Bose institute
Research interest- Cell biology of thermoacidophilc archaeon
Former Graduate student in Department of Biological Sciences
@ Bose institute
Research interest- Cell biology of thermoacidophilc archaeon
Reposted by Arghya Bhowmick
Honored to present our research on archaeal toxin-antitoxin systems at the International Thermophiles Congress 2025—great discussions and inspiring science all around! #Thermophiles2025 #Microbiology @IndiaDST @ANRFIndia @bose_institute
September 12, 2025 at 5:26 AM
Honored to present our research on archaeal toxin-antitoxin systems at the International Thermophiles Congress 2025—great discussions and inspiring science all around! #Thermophiles2025 #Microbiology @IndiaDST @ANRFIndia @bose_institute
Caught in the act! 📸 Negative-stained TEM of the hot and acidic life of Sulfolobus acidocaldarius, snapped mid-division while waving hi with its pilli. 😁
#archaeasky
#microsky
#archaea
#archaeasky
#microsky
#archaea
August 14, 2025 at 6:19 AM
Caught in the act! 📸 Negative-stained TEM of the hot and acidic life of Sulfolobus acidocaldarius, snapped mid-division while waving hi with its pilli. 😁
#archaeasky
#microsky
#archaea
#archaeasky
#microsky
#archaea
Preprint drop! 🚨 Rhobin-tag your proteins and watch Saci glow at high temps! 🔥 Bright, photostable, live-cell imaging made possible with JF dyes. Huge thanks to @samjlord.bsky.social @acharlesorszag.bsky.social @mullinslab.bsky.social and Bo Huang lab at UCSF.😊
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
De novo designed bright, hyperstable rhodamine binders for fluorescence microscopy
De novo protein design has emerged as a powerful strategy with the promise to create new tools. The practical performance of designed fluorophore binders, however, has remained far from meeting fluore...
www.biorxiv.org
June 25, 2025 at 5:57 PM
Preprint drop! 🚨 Rhobin-tag your proteins and watch Saci glow at high temps! 🔥 Bright, photostable, live-cell imaging made possible with JF dyes. Huge thanks to @samjlord.bsky.social @acharlesorszag.bsky.social @mullinslab.bsky.social and Bo Huang lab at UCSF.😊
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Arghya Bhowmick
We are excited to present Jingwei Xu @xujwet.bsky.social from @ethz.ch for #MSS2025 🤩 His work focuses on the evolutionary origins of cytoskeletons, using advanced microscopy techniques to reveal the cell biology of Asgard archaea 🦠 Only one week left to sign up! ➡️ tinyurl.com/yc4jxdvz
May 21, 2025 at 11:22 AM
We are excited to present Jingwei Xu @xujwet.bsky.social from @ethz.ch for #MSS2025 🤩 His work focuses on the evolutionary origins of cytoskeletons, using advanced microscopy techniques to reveal the cell biology of Asgard archaea 🦠 Only one week left to sign up! ➡️ tinyurl.com/yc4jxdvz
Reposted by Arghya Bhowmick
Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation | PNAS https://www.pnas.org/doi/abs/10.1073/pnas.2423648122?af=R
Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation | PNAS
Enhancement of the cyclization of membrane lipids GDGTs (glycerol dialkyl glycerol tetraethers) is a critical strategy for archaea to adapt to vari...
www.pnas.org
May 12, 2025 at 11:25 PM
Cyclization of archaeal membrane lipids impacts membrane protein activity and archaellum formation | PNAS https://www.pnas.org/doi/abs/10.1073/pnas.2423648122?af=R
Reposted by Arghya Bhowmick
Mark in your calendars! The Molecular Biology of Archaea meeting (MBoA) 2026!
Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated to Archaea.
Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated to Archaea.
April 18, 2025 at 2:27 PM
Mark in your calendars! The Molecular Biology of Archaea meeting (MBoA) 2026!
Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated to Archaea.
Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated to Archaea.
Reposted by Arghya Bhowmick
Preprint alert! I’m publishing my last paper from my postdoc work on archaeal cell biology, with @mullinslab.bsky.social, @archaellum.bsky.social, @samjlord.bsky.social, @marleenvw.bsky.social, @arghya93.bsky.social, and more great folks (thread below with more details)
April 16, 2025 at 6:55 PM
Preprint alert! I’m publishing my last paper from my postdoc work on archaeal cell biology, with @mullinslab.bsky.social, @archaellum.bsky.social, @samjlord.bsky.social, @marleenvw.bsky.social, @arghya93.bsky.social, and more great folks (thread below with more details)
🚨 Preprint alert!
Our new work is out now 🤩
Turns out even spherical archaeal cells have a clever way of organizing and segregating their chromosomes - using a bipolar SegAB structure!
Deeply grateful to have worked with @acharlesorszag.bsky.social @samjlord.bsky.social @mullinslab.bsky.social
Our new work is out now 🤩
Turns out even spherical archaeal cells have a clever way of organizing and segregating their chromosomes - using a bipolar SegAB structure!
Deeply grateful to have worked with @acharlesorszag.bsky.social @samjlord.bsky.social @mullinslab.bsky.social
Preprint alert! I’m publishing my last paper from my postdoc work on archaeal cell biology, with @mullinslab.bsky.social, @archaellum.bsky.social, @samjlord.bsky.social, @marleenvw.bsky.social, @arghya93.bsky.social, and more great folks (thread below with more details)
April 16, 2025 at 7:45 PM
🚨 Preprint alert!
Our new work is out now 🤩
Turns out even spherical archaeal cells have a clever way of organizing and segregating their chromosomes - using a bipolar SegAB structure!
Deeply grateful to have worked with @acharlesorszag.bsky.social @samjlord.bsky.social @mullinslab.bsky.social
Our new work is out now 🤩
Turns out even spherical archaeal cells have a clever way of organizing and segregating their chromosomes - using a bipolar SegAB structure!
Deeply grateful to have worked with @acharlesorszag.bsky.social @samjlord.bsky.social @mullinslab.bsky.social
Reposted by Arghya Bhowmick
"Advancing archaeal research through FAIR resource and data sharing, and inclusive community building" by Solenne Ithurbide, Nicole Buan & Stefan Schulze.
rdcu.be/efZTL
@nbuan.bsky.social @archaeapowerhour.bsky.social @archaeabio.bsky.social #ArchaeaSky #MicroSky
rdcu.be/efZTL
@nbuan.bsky.social @archaeapowerhour.bsky.social @archaeabio.bsky.social #ArchaeaSky #MicroSky
Advancing archaeal research through FAIR resource and data sharing, and inclusive community building
Communications Biology - Archaeal research and its growing importance have benefited from a community that is engaged in various collaborative efforts, which are highlighted here with examples for...
rdcu.be
April 1, 2025 at 2:58 PM
"Advancing archaeal research through FAIR resource and data sharing, and inclusive community building" by Solenne Ithurbide, Nicole Buan & Stefan Schulze.
rdcu.be/efZTL
@nbuan.bsky.social @archaeapowerhour.bsky.social @archaeabio.bsky.social #ArchaeaSky #MicroSky
rdcu.be/efZTL
@nbuan.bsky.social @archaeapowerhour.bsky.social @archaeabio.bsky.social #ArchaeaSky #MicroSky
Reposted by Arghya Bhowmick
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6
March 21, 2025 at 3:16 PM
Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6
Sulfo-buddies going splitsville! 😆
March 27, 2025 at 7:02 AM
Sulfo-buddies going splitsville! 😆
Reposted by Arghya Bhowmick
New results from the lab!!!
Our recent study analyzes the archaeal SRP system, focusing on the FtsY protein's N-terminal domain. This work highlights the key role of the A domain and N-terminal alpha helices in generating the functional TC in archaea.
www.sciencedirect.com/science/arti...
Our recent study analyzes the archaeal SRP system, focusing on the FtsY protein's N-terminal domain. This work highlights the key role of the A domain and N-terminal alpha helices in generating the functional TC in archaea.
www.sciencedirect.com/science/arti...
Unravelling the role of the A domain and N-terminal alpha-helices of FtsY in archaeal signal recognition particle
Signal recognition particle (SRP) system is critical for protein translocation across membranes in all domains of life. In archaea, this pathway relie…
www.sciencedirect.com
March 5, 2025 at 4:31 PM
Reposted by Arghya Bhowmick
Great to see that Department of Science and Technology, Government of India showcased our work on VapBC4 toxin-antitoxin system of Sulfolobus.
pib.gov.in/PressRelease...
pib.gov.in/PressRelease...
December 25, 2024 at 9:59 AM
Great to see that Department of Science and Technology, Government of India showcased our work on VapBC4 toxin-antitoxin system of Sulfolobus.
pib.gov.in/PressRelease...
pib.gov.in/PressRelease...
Reposted by Arghya Bhowmick
"Ants solving a geometric problem and it's amazing."
This is a great example of 'emergent phenomenon':
- None of the ants understand the problem they're solving.
- None of them can see the whole shape.
- A series of small decisions or rules add up to something with a new layer of complexity.
This is a great example of 'emergent phenomenon':
- None of the ants understand the problem they're solving.
- None of them can see the whole shape.
- A series of small decisions or rules add up to something with a new layer of complexity.
Son hormigas resolviendo un problema geométrico y es para flipar en colores.
December 25, 2024 at 5:54 PM
"Ants solving a geometric problem and it's amazing."
This is a great example of 'emergent phenomenon':
- None of the ants understand the problem they're solving.
- None of them can see the whole shape.
- A series of small decisions or rules add up to something with a new layer of complexity.
This is a great example of 'emergent phenomenon':
- None of the ants understand the problem they're solving.
- None of them can see the whole shape.
- A series of small decisions or rules add up to something with a new layer of complexity.
Last day at the @aglab-2024.bsky.social , Bose Institute, and its an emotional one- feeling sad to leave as well as excited for what lies ahead. Grateful for all the memories here and looking forward to joining the Mullins Lab at UCSF to do wonderful science with his team..
#bittersweet_moment
#bittersweet_moment
November 22, 2024 at 10:17 AM
Last day at the @aglab-2024.bsky.social , Bose Institute, and its an emotional one- feeling sad to leave as well as excited for what lies ahead. Grateful for all the memories here and looking forward to joining the Mullins Lab at UCSF to do wonderful science with his team..
#bittersweet_moment
#bittersweet_moment
Hard work pays off. 😌
Huge thanks to
@aglab-2024.bsky.social members @bose_institute
and special mention to
@archaellum.bsky.social lab members
for their invaluable collaboration and insights that made this work possible. 😃 Also grateful to
@EMBO
for funding and making this work possible.
Huge thanks to
@aglab-2024.bsky.social members @bose_institute
and special mention to
@archaellum.bsky.social lab members
for their invaluable collaboration and insights that made this work possible. 😃 Also grateful to
@EMBO
for funding and making this work possible.
The story is finally out!!! Here, we showed multiple functions of the VapBC4 toxin-antitoxin of Sulfolobus acidocaldarius under stress. Thanks to @archaellum.bsky.social for an excellent collaboration.
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Role of VapBC4 toxin-antitoxin system of Sulfolobus acidocaldarius in heat stress adaptation | mBio
This research enhances our knowledge of toxin-antitoxin (TA) systems in archaea, specifically in the thermoacidophilic archaeon Sulfolobus acidocaldarius. TA systems are widespread in both bacterial and archaeal genomes, indicating their evolutionary ...
journals.asm.org
November 13, 2024 at 7:22 PM
Hard work pays off. 😌
Huge thanks to
@aglab-2024.bsky.social members @bose_institute
and special mention to
@archaellum.bsky.social lab members
for their invaluable collaboration and insights that made this work possible. 😃 Also grateful to
@EMBO
for funding and making this work possible.
Huge thanks to
@aglab-2024.bsky.social members @bose_institute
and special mention to
@archaellum.bsky.social lab members
for their invaluable collaboration and insights that made this work possible. 😃 Also grateful to
@EMBO
for funding and making this work possible.