Santi Priego
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santyy31.bsky.social
Santi Priego
@santyy31.bsky.social
A curious enthusiast of plant genetics, epigenetics and metabolism
Reposted by Santi Priego
Pipeline release! nf-core/methylong v2.0.0 - 3!

Please see the changelog: https://github.com/nf-core/methylong/releases/tag/2.0.0
Release 3 · nf-core/methylong
github.com
November 21, 2025 at 2:26 AM
Reposted by Santi Priego
New paper is online! We used single cell RNA-seq & phylogenetics to identify 2 additional cell type specific TFs that control late-stage vinca alkaloid biosynthesis. The key insights originated from Camptotheca, another species that produces alkaloids. doi.org/10.1111/nph.... #PlantScience #SecMet
November 10, 2025 at 1:29 PM
Reposted by Santi Priego
🌱💡 Did you know nuclear pores do more than let molecules in & out? Our new study shows they also act as control hubs for pri-miRNA transcription & processing!
A surprising twist in how plants fine-tune gene silencing.
academic.oup.com/nar/article/...
Validate User
academic.oup.com
September 18, 2025 at 10:43 AM
Reposted by Santi Priego
🚀 Exciting update: "Cookbook for Plant Genome Sequences" now includes an updated overview figure! 🌱🔬
Check out how to run a plant genome sequencing project:
www.preprints.org/manuscript/2...
#Genomics #LongReads #Bioinformatics
@puckerlab.bsky.social
September 16, 2025 at 4:37 AM
Reposted by Santi Priego
Join us in Málaga in 2026!!!
🌟 𝐅𝐢𝐫𝐬𝐭 𝐰𝐚𝐯𝐞 𝐨𝐟 𝐜𝐨𝐧𝐟𝐢𝐫𝐦𝐞𝐝 𝐤𝐞𝐲𝐧𝐨𝐭𝐞 𝐬𝐩𝐞𝐚𝐤𝐞𝐫𝐬 🗣️

Excited to share the first members of our keynote lineup!
🔹 Federico Ariel
🔹 Brian Gregory
🔹 Polly Hsu @pollyhsulab.bsky.social
🔹 Rosa Lozano-Durán @geminiteamlab.bsky.social
🔹 Hervé Vaucheret

More speakers and more info coming soon!
August 30, 2025 at 12:46 PM
Reposted by Santi Priego
Excited to share some data from my PhD project at #ENFC2025
Join me to discuss about Lotus and Tomato SymRK 🌱
August 28, 2025 at 10:34 AM
Reposted by Santi Priego
Thinking of starting a plant genome sequencing project?

Check out this step-by-step guide:

Cookbook for Plant Genome Sequences
📖 www.preprints.org/manuscript/2...

#Genomics #Bioinformatics #LongReads
@puckerlab.bsky.social
www.preprints.org
August 22, 2025 at 5:08 AM
Reposted by Santi Priego
So excited to be at #ESEB2025 presenting poster 221 today!☀️

Check out our chromosome-level genome of Bostrychia, a red alga from the complex Ceramiales order, revealing massive genome expansion by giant Plavaka DNA transposons, the evolution of expanded gene families and UV sex chromosomes!
August 19, 2025 at 8:31 AM
Reposted by Santi Priego
Extremely happy to see our withanolide biosynthesis paper out in @natcomms.nature.comrdcu.be/evHOF
Fantastic team effort with the Pucker group @bpucker.bsky.social@puckerlab.bsky.social‬ at @unibonn.bsky.social and Heretsch, Herde and Witte groups at @unihannover.bsky.social. Funded by @dfg.de
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
Nature Communications - Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown....
rdcu.be
July 10, 2025 at 5:50 PM
Reposted by Santi Priego
New (English!) episode from the wonderful TRR356 podcast on plant-microbe interactions, and this time I got to join! Have a listen to hear more about the work we do to understand how plants and beneficial microbes interact 👇

podcasts.apple.com/de/podcast/p...

#SciComm 🧪 #PlantScience
#5 Rooted in Symbiosis: How Plants and Microbes Work Together - With Tora Fougner-Økland and Jonathan Jelen
Podcast-Folge · Pflanzen und ihr Mikrokosmos · 03.07.2025 · 21 Min.
podcasts.apple.com
July 3, 2025 at 2:44 PM
Reposted by Santi Priego
Plant specialised metabolites modulate the molecular signatures of host-bacteria and bacteria-bacteria interactions https://www.biorxiv.org/content/10.1101/2025.06.06.658260v1
June 9, 2025 at 6:03 AM
Reposted by Santi Priego
Just back from the #COST Action meeting in Hamburg, where I had the chance to present some of our research on fungal extracellular vesicles and sRNA transport.
Always a pleasure to exchange ideas and reconnect with the #exRNA community!
June 15, 2025 at 4:40 PM
Reposted by Santi Priego
Subfunctionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae

From: www.pnas.org/doi/10.1073/...

#PlantScience #SecMet
Subfunctionalization and epigenetic regulation of a biosynthetic gene cluster in Solanaceae | PNAS
Biosynthetic gene clusters (BGCs) are sets of often heterologous genes that are genetically and functionally linked. Among eukaryotes, BGCs are mos...
www.pnas.org
May 5, 2025 at 11:30 AM
Reposted by Santi Priego
Happy to share our latest publication in the Weiberg Lab: www.pnas.org/doi/10.1073/...

Here we uncovered how fungal argonautes regulate bidirectional cross-kingdom RNAi during infection of plants.

Big thanks to @oberkoflerlorenz.bsky.social and everyone who was involved in the story.
https://pnas.org/doi/10.1073/pn…
April 28, 2025 at 10:27 AM
Reposted by Santi Priego
New study with @petrollromy.bsky.social @borglab.bsky.social traces the evolution of epigenetic silencing in plants. Deep conservation of PRC2-mediated H3K27me3 marks across green algae suggest ancient, conserved networks of gene repression.

🔗 doi.org/10.1093/molb...

#evobio #molevol #plants
The Expansion and Diversification of Epigenetic Regulatory Networks Underpins Major Transitions in the Evolution of Land Plants
Abstract. Epigenetic silencing is essential for regulating gene expression and cellular diversity in eukaryotes. While DNA and H3K9 methylation silence tra
doi.org
April 17, 2025 at 5:32 PM
Reposted by Santi Priego
Plants epigenetically control the production of pharmaceutically relevant active ingredients!🌿 #LMU Researchers led by Claude Becker have discovered a #genecluster that regulates the biosynthesis of withanolides in Physalis grisea - with important implications for alternative pesticides & drugs.
How plants epigenetically regulate their chemical defences
A new study demonstrates how plants of the nightshade family produce pharmaceutically valuable compounds and how this biosynthesis is epigenetically regulated.
www.lmu.de
March 6, 2025 at 12:39 PM
Reposted by Santi Priego
Preprint alert: Here we report MMF1 - "a microbiota receptor” - through which Arabidopsis plants perceive their soil microbiome. Perception optimises root microbiome composition, immune status and ultimately leads to better growth.

Happy reading...
www.biorxiv.org/content/10.1...
A TNL receptor mediates microbiome feedbacks in Arabidopsis
Plant performance depends on the soil microbiome. While microbiome feedbacks are well documented, the mechanisms by which plants perceive and mediate these feedbacks remain unclear. We established a f...
www.biorxiv.org
February 27, 2025 at 7:14 AM
Reposted by Santi Priego
🚨Preprint Alert🚨 I'm really happy to finally share our exploits in red algae and introduce the wider community to Bostrychia, the new model system we have been developing to tackle the molecular biology of red algae. Isn't she a beauty? Thread below 🧵 1/8 www.biorxiv.org/content/10.1...
February 12, 2025 at 8:37 AM
Reposted by Santi Priego
Nuevo episodio desde MÉXICO🎙️Ya podéis escuchar nuestra conversación con el brillante Pau Luque desde la FIL de Guadalajara. Hablamos de la intersección entre filosofía y literatura, de Iris Murdoch, Martha Nussbaum, Barthes y más. ADORAMOS A PAU y vosotras también💘🪡
open.spotify.com/episode/07jy...
Ética y literatura: cruce de caminos, con Pau Luque
Punzadas Sonoras · Episode
open.spotify.com
December 12, 2024 at 11:39 AM
Reposted by Santi Priego
My Tidyverse local synteny visualizer is up on GitHub: github.com/cxli233/Tidy...

GitHub page contains 2 example datasets, as well as step-by-step instruction & explanations on how it works. Details on required input data are discussed in the GitHub page. Let me know if you run into issues.
December 12, 2024 at 2:03 AM