Rushani Wijesuriya
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rush-099.bsky.social
Rushani Wijesuriya
@rush-099.bsky.social
Postdoctoral biostatistician at Murdoch Children's Research Institute and University of Melbourne★Biostatistics research : causal inference and missing data problems in child health, population allergy and social epidemiology ★she/her ★Views my own
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Hot off the press! 📣📣In this tutorial we illustrate available multiple imputation approaches for handling longitudinal data including when they are clustered within higher level clusters. A reproducible example with R and Stata code provided! #OpenAccess

onlinelibrary.wiley.com/doi/10.1002/...
Multiple Imputation for Longitudinal Data: A Tutorial
Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thu....
onlinelibrary.wiley.com
Reposted by Rushani Wijesuriya
#ViCBiostat Summer School 13-20 Feb 2026

#Causal inference
#Estimands in trials
#Cluster randomised trials
Advanced #meta-analysis

In Melbs and online.
More details to come.
www.vicbiostat.org.au
November 12, 2025 at 4:12 AM
Reposted by Rushani Wijesuriya
My own TLDR for the message from this paper:

statsepi.substack.com/p/sorry-what...
October 28, 2025 at 11:34 AM
Reposted by Rushani Wijesuriya
NEW PAPER!!! "Causal Machine Learning Methods and Use of Cross‐Fitting in Settings With High‐Dimensional Confounding"

led by Susie Ellul, with Stijn Vansteelandt & John Carlin
Published in Stats in Med

Check it out 👇
onlinelibrary.wiley.com/doi/10.1002/...

#EpiSky #CausalSky
Causal Machine Learning Methods and Use of Cross‐Fitting in Settings With High‐Dimensional Confounding
Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the p...
onlinelibrary.wiley.com
September 25, 2025 at 2:35 AM
Reposted by Rushani Wijesuriya
Awarded every two years by Australian Academy of Science,
the Moran Medal honours outstanding Australian scientists in statistics & related fields. Huge congratulations to our Co-Director @margaritamb.bsky.social on this well-deserved recognition! 🎉🥳 #WomenInSTEM #ResearchExcellence
A few weeks ago I went to Canberra to receive the Moran Medal at the lovely Shine Dome of the Australian Academy of Science (@science.org.au). It was a huge honour, and wonderful to hear talks from all corners of science and to learn about the Academy's great work supporting science
- pics below!
October 8, 2025 at 4:04 AM
Reposted by Rushani Wijesuriya
NEW PAPER! (in press in EPIDEMIOLOGY)

Have you wondered:
- How to specify a target trial: as an ideal trial or something else?
- What biases do target trial emulations and actual RCTs share?
- How does it all relate to potential outcomes?

Read here! 👉 arxiv.org/abs/2405.10026
#EpiSky #CausalSky
The ideal trial: defining causal estimands that balance relevance and feasibility in target trial emulations and actual randomized trials
Causal inference is the goal of randomized trials and many observational studies. The first step in a formal causal inference framework is to define the causal estimand, and in both types of study thi...
arxiv.org
September 9, 2025 at 11:23 PM
Reposted by Rushani Wijesuriya
🚨New method! So proud to see work led by @cttc101.bsky.social w/ @margaritamb.bsky.social @ghazalehd.bsky.social now available as an R package 📦
A powerful tool for estimating intervention effects via multiple mediators w/real examples to guide you!
Check it out ⬇️
#epitwitter #causaltwitter #rstats
1/ NEW R PACKAGE! For estimating the impact of potential interventions on multiple mediators in countering exposure effects (led by @cttc101.bsky.social)

- Paper👉 tinyurl.com/ye26jsps
- Package👉 tinyurl.com/yuh4kens

Thread shows published examples of how the method can be used! #EpiSky #CausalSky
tinyurl.com
July 10, 2025 at 4:14 AM
Reposted by Rushani Wijesuriya
🚨 A MUST-READ by John Carlin and @margaritamb.bsky.social including 6 commentaries and rejoinder

NOW PUBLISHED:
“On the Uses and Abuses of Regression Models: A Call for Reform of Statistical Practice and Teaching”
July 2, 2025 at 8:52 AM
Reposted by Rushani Wijesuriya
1/ NEW R PACKAGE! For estimating the impact of potential interventions on multiple mediators in countering exposure effects (led by @cttc101.bsky.social)

- Paper👉 tinyurl.com/ye26jsps
- Package👉 tinyurl.com/yuh4kens

Thread shows published examples of how the method can be used! #EpiSky #CausalSky
tinyurl.com
July 10, 2025 at 1:30 AM
Reposted by Rushani Wijesuriya
📣 📣NEW PAPER providing guidance on best practice for using multiple imputation when estimating interventional mediation effects, considering missingness mechanism, multiple imputation model specification, & variance estimation
#CausalSky #EpiSky

Read more 👇🏽
journals.lww.com/epidem/abstr...
Handling multivariable missing data in causal mediation... : Epidemiology
miologic studies. However, guidance is lacking on best practice for using multiple imputation when estimating interventional mediation effects, specifically regarding the role of missingness mechanism...
journals.lww.com
April 2, 2025 at 6:39 AM
Reposted by Rushani Wijesuriya
Over the moon to have received the Moran Medal from the Australian Academy of Science!🥳

Amazing recognition, hopefully highlighting the key role of biostats & causal inference in high-quality research vimeo.com/1065735362
tinyurl.com/2m3dx2ms
@cebu-melbourne.bsky.social @vicbiostat.bsky.social
Professor Margarita Moreno-Betancur - Moran Medal 2025
This is "Professor Margarita Moreno-Betancur - Moran Medal 2025" by Australian Academy of Science on Vimeo, the home for high quality videos and the people…
vimeo.com
April 8, 2025 at 5:05 AM
Reposted by Rushani Wijesuriya
Thrilled to share our new preprint on causal ML for mediation analysis! We introduce causal ML estimators for interventional effects explicitly mapped to target trials assessing hypothetical interventions inducing distinct shifts in joint mediator distributions📊 📈🧪
#CausalSky #EpiSky
link 📈🤖
Causal machine learning for high-dimensional mediation analysis using interventional effects mapped to a target trial (Chen, Vansteelandt, Burgner et al) Causal mediation analysis examines causal pathways linking exposures to disease. The estimation of interventional effects, which are me
April 24, 2025 at 2:51 AM
Reposted by Rushani Wijesuriya
Recording of my talk @causalab.bsky.social on using m-DAGs to guide the treatment of missing data now available 👇 #EpiSky #CausalSky
Check out the last Methods Series talk now on YouTube:
youtu.be/QuQnZ4don54?...
2 weeks away!

@margaritamb.bsky.social (Murdoch Children's Research Institute, University of Melbourne) continues the 2025 Methods Series @ki.se.

📆 April 22, 2025
⏰ 13.00 CEST/7.00 ET
📍 All Methods Series talks virtual

Register now 👇
stats.sender.net/forms/e7JD1d...
#publichealth #causalinference
April 23, 2025 at 6:48 AM
Reposted by Rushani Wijesuriya
"Using missingness directed acyclic graphs (m-DAGs) to guide the treatment of multivariable missing data in epidemiological studies"

Don't miss the next #CIIG seminar with @margaritamb.bsky.social on 7th April 2025 at *9am* BST!

Register at: turing-uk.zoom.us/meeting/regi...

#EpiSky #CausalSky
March 26, 2025 at 7:44 PM
Reposted by Rushani Wijesuriya
🎉 Our VERY FIRST newsletter is here! 📬Use the link to access it and learn more about our group and the work/activities we do: shorturl.at/bzmio
@vicbiostat.bsky.social
March 12, 2025 at 4:29 AM
Reposted by Rushani Wijesuriya
Thrilled to have received this funding for my causal inference research program - with my amazing team we shall continue to advance methods and provide expertise in this key area for another 5 years!!! 🥳☺️ #CausalSky #EpiSky
Exciting Monday news with two of our brilliant researchers awarded NHMRC Investigator Grants 🎊

Congratulations Margarita Moreno-Betancur @margaritamb.bsky.social and Julie Simpson @julieasimpson50.bsky.social

More:
www.vicbiostat.org.au/news

@mischhub.bsky.social @cebu-melbourne.bsky.social
News
www.vicbiostat.org.au
February 24, 2025 at 6:44 AM
Reposted by Rushani Wijesuriya
Really happy with how this went! Our first missing data workshop completely grounded on the use of missingness DAGs (m-DAGs) to specify missingness assumptions 😀 #EpiSky #CausalSky
Another successful workshop from our missing data methods research group ✔️Led by Margarita Moreno-Betancur @margaritamb.bsky.social, with presenters Kate Lee, Ghazaleh Dashti @ghazalehd.bsky.social, Jiaxin Zhang, Cattram Nguyen, Melissa Middleton and Jessica Xu.

Thank you to all who came along!
February 12, 2025 at 11:22 PM
Reposted by Rushani Wijesuriya
Our research methods and software training course timetable for 2025 is out! check it out here 👇 www.mcri.edu.au/research/res...
CEBU course timetable - Murdoch Children's Research Institute
2025 CEBU course timetable at MCRI. Enhance your research skills with our short courses in clinical research methods, data management, and statistical analysis.
www.mcri.edu.au
February 11, 2025 at 5:56 AM
Reposted by Rushani Wijesuriya
NEW COMMENTARY in Epidemiology on causal estimands in studies of pre-diagnostic exposures and cancer survival

#EpiSkye #CausalSky

journals.lww.com/epidem/citat...
Pre-diagnostic exposures and cancer survival: Can a... : Epidemiology
An abstract is unavailable. This article is available as a PDF only.
journals.lww.com
January 30, 2025 at 7:29 AM
Reposted by Rushani Wijesuriya
New paper!! We find that prevalent exposure designs are very common in dementia research, explain why they are ill-suited for causal inference, and show how the target trial framework helps us move beyond them.

Read here👇 www.thelancet.com/journals/lan...
Moving beyond the prevalent exposure design for causal inference in dementia research
As randomised trials are not always feasible or practical, observational studies remain crucial for addressing many causal questions in the dementia prevention field. Through a systematic search, we f...
www.thelancet.com
February 2, 2025 at 11:52 PM
Reposted by Rushani Wijesuriya
NOW PUBLISHED! Correction to: “Canonical causal diagrams to guide the treatment of missing data in epidemiologic studies" doi.org/10.1093/aje/...

Grateful to have had the opportunity to correct our paper translating missingness DAGs (m-DAGs) into epidemiological practice #CausalSky #EpiSky
Correction to: “Canonical causal diagrams to guide the treatment of missing data in epidemiologic studies”
Moreno-Betancur et al.1 report and correct here errors in their article “Canonical causal diagrams to guide the treatment of missing data in epidemiologic
doi.org
January 28, 2025 at 2:19 AM
Reposted by Rushani Wijesuriya
WORKSHOPS! On causal inference, missing data and SMARTs, part of the ViCBiostat Summer School (10-14 Feb, hybrid). For more details & registration visit: www.vicbiostat.org.au/short-courses

#CausalSky #EpiSky
January 22, 2025 at 5:08 AM
Hot off the press! 📣📣In this tutorial we illustrate available multiple imputation approaches for handling longitudinal data including when they are clustered within higher level clusters. A reproducible example with R and Stata code provided! #OpenAccess

onlinelibrary.wiley.com/doi/10.1002/...
Multiple Imputation for Longitudinal Data: A Tutorial
Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thu....
onlinelibrary.wiley.com
January 27, 2025 at 4:14 AM