Robert Califf
@robcaliff.bsky.social
Another useful update from YLE. Includes a poll on future update on deep dive on menopause.
open.substack.com/pub/yourloca...
open.substack.com/pub/yourloca...
Infant formula botulism cluster, black box warning for HRT, flu is waking up, new blood pressure guidelines, and more
This is your weekly Dose.
open.substack.com
November 10, 2025 at 2:29 PM
Another useful update from YLE. Includes a poll on future update on deep dive on menopause.
open.substack.com/pub/yourloca...
open.substack.com/pub/yourloca...
YLE calling for action to promote science, public health and evidence based policy.
open.substack.com/pub/yourloca...
open.substack.com/pub/yourloca...
A good defense demands offense
And what it looks like
open.substack.com
November 7, 2025 at 2:03 PM
YLE calling for action to promote science, public health and evidence based policy.
open.substack.com/pub/yourloca...
open.substack.com/pub/yourloca...
Reposted by Robert Califf
The JAMA Summit on Firearm Violence gathered experts from medicine, policy, engineering, and community groups to develop a plan for reducing firearm harms by 2040.
Learn more in this Special Communication: ja.ma/43hclqa
Learn more in this Special Communication: ja.ma/43hclqa
November 5, 2025 at 12:00 PM
The JAMA Summit on Firearm Violence gathered experts from medicine, policy, engineering, and community groups to develop a plan for reducing firearm harms by 2040.
Learn more in this Special Communication: ja.ma/43hclqa
Learn more in this Special Communication: ja.ma/43hclqa
Back to Pasteur. Raw milk is not our largest public health issue, but the purported benefits are hypothetical and not empirically proven and the risks are basic.
open.substack.com/pub/pauloffi...
open.substack.com/pub/pauloffi...
See No Evil
Why did RFK Jr. limit the reporting of certain foodborne illnesses?
open.substack.com
November 4, 2025 at 12:17 PM
Back to Pasteur. Raw milk is not our largest public health issue, but the purported benefits are hypothetical and not empirically proven and the risks are basic.
open.substack.com/pub/pauloffi...
open.substack.com/pub/pauloffi...
What I learned talking to MAHA moms
Was honored to be on the "Why Should I Trust You?" podcast
open.substack.com
November 3, 2025 at 2:17 PM
Reposted by Robert Califf
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word
www.scripps.edu/news-and-eve...
www.scripps.edu/news-and-eve...
Scripps Research scientists launch new digital clinical trial to test repurposed drug for long COVID symptom relief
www.scripps.edu
October 31, 2025 at 5:07 PM
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word
www.scripps.edu/news-and-eve...
www.scripps.edu/news-and-eve...
Reposted by Robert Califf
This weekend, 12% of Americans are set to lose crucial food assistance due to the govt shutdown — the majority of them are children or elderly.
Cc:
@washingtonpost.com
Cc:
@washingtonpost.com
October 31, 2025 at 5:54 PM
This weekend, 12% of Americans are set to lose crucial food assistance due to the govt shutdown — the majority of them are children or elderly.
Cc:
@washingtonpost.com
Cc:
@washingtonpost.com
Reposted by Robert Califf
Nearly a fifth of American households with children rely on SNAP to buy groceries.
cc: @washingtonpost.com
cc: @washingtonpost.com
October 31, 2025 at 5:54 PM
Nearly a fifth of American households with children rely on SNAP to buy groceries.
cc: @washingtonpost.com
cc: @washingtonpost.com
Really sad to see this, knowing how many people were being helped as the foundation is destroyed.
www.statnews.com/2025/10/30/s...
www.statnews.com/2025/10/30/s...
Trump cuts have decimated the federal addiction and mental health agency
The Trump administration has dismantled big chunks of the federal agency focused on mental health and addiction treatment, reducing its staff by more than half
www.statnews.com
October 30, 2025 at 8:08 PM
Really sad to see this, knowing how many people were being helped as the foundation is destroyed.
www.statnews.com/2025/10/30/s...
www.statnews.com/2025/10/30/s...
Minimizing the nonfatal toll of Covid 19 infection would be a big mistake.
www.nature.com/articles/s44...
www.nature.com/articles/s44...
COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years - npj Dementia
npj Dementia - COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years
www.nature.com
October 30, 2025 at 3:10 PM
Minimizing the nonfatal toll of Covid 19 infection would be a big mistake.
www.nature.com/articles/s44...
www.nature.com/articles/s44...
The Food Additive Wars
Why a Patchwork of State Bans Creates More Problems Than It Solves
open.substack.com
October 29, 2025 at 12:25 AM
"We should be building on its extraordinary life-saving pandemic success, not turning our back on it!"
open.substack.com/pub/erictopo...
open.substack.com/pub/erictopo...
How mRNA Vaccines Can Help Fight Cancer
Turning "cold" tumors "hot"
open.substack.com
October 23, 2025 at 4:10 PM
"We should be building on its extraordinary life-saving pandemic success, not turning our back on it!"
open.substack.com/pub/erictopo...
open.substack.com/pub/erictopo...
For those who thought RFK Jr would "clean up" industry connections, this is worth a read and reflection.
www.foodpolitics.com/2025/10/http...
www.foodpolitics.com/2025/10/http...
Trump food officials with ties to industry: Civil Eats has a list. - Food Politics by Marion Nestle
Many of the president’s top officials at the USDA, EPA, HHS, and FDA have connections to chemical, agribusiness, or fossil fuel interests.
www.foodpolitics.com
October 23, 2025 at 2:44 PM
For those who thought RFK Jr would "clean up" industry connections, this is worth a read and reflection.
www.foodpolitics.com/2025/10/http...
www.foodpolitics.com/2025/10/http...
This is fascinating. Hard to prove, but the protean effects of "GLP1's" points out how surprised we are when we perturb the human system with an intervention.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial
The cardioprotective effects of semaglutide were independent of baseline adiposity
and weight loss and had only a small association with waist circumference, suggesting
some mechanisms for benefit bey...
www.thelancet.com
October 23, 2025 at 10:47 AM
This is fascinating. Hard to prove, but the protean effects of "GLP1's" points out how surprised we are when we perturb the human system with an intervention.
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
This seems so obvious but is said so seldom. Good to see these experts put it out there in plain English.
www.statnews.com/2025/10/21/h...
www.statnews.com/2025/10/21/h...
The U.S. experiment with profit-driven health care has failed
“The market competition, managed care, and ‘corporate efficiency’ that economists prescribed as the cure for health care inflation instead accelerated it.”
www.statnews.com
October 22, 2025 at 3:09 PM
This seems so obvious but is said so seldom. Good to see these experts put it out there in plain English.
www.statnews.com/2025/10/21/h...
www.statnews.com/2025/10/21/h...
This will be a test of whether key federal agencies (USDA, HHS, etc.) can work with academic communities, especially those with strong vet, med and public health schools, and with states and counties to solve this problem.
www.nytimes.com/2025/10/22/h...
www.nytimes.com/2025/10/22/h...
Bird Flu Is Back
www.nytimes.com
October 22, 2025 at 2:35 PM
This will be a test of whether key federal agencies (USDA, HHS, etc.) can work with academic communities, especially those with strong vet, med and public health schools, and with states and counties to solve this problem.
www.nytimes.com/2025/10/22/h...
www.nytimes.com/2025/10/22/h...
Useful stuff from YLE. At a minimum I hope there will be popular demand for registering supplements and putting their ingredients in the label.
open.substack.com/pub/yourloca...
open.substack.com/pub/yourloca...
Lead in protein powders, governors unite, and mammograms targeted.
In this week's Dose: what's going on with lead in protein powders, 15 governors unite for public health, and the falsehoods swirling around mammograms.
open.substack.com
October 20, 2025 at 2:17 PM
Useful stuff from YLE. At a minimum I hope there will be popular demand for registering supplements and putting their ingredients in the label.
open.substack.com/pub/yourloca...
open.substack.com/pub/yourloca...