Riikka Kivelä
@riikka-k.bsky.social
Associate Professor in Exercise Physiology focusing on vascular biology, heart and skeletal muscle, Endurance sport enthusiastic, mother of 🏃♀️🏃.
Excited to share our new study showing how rhabdomyosarcoma cells respond differently to the inhibition of cholesterol synthesis compared to healthy myoblasts. Great work by a recent PhD Nebeyu Gizaw🎓
#UniHelsinki @wrihelsinki.bsky.social #UniJyvaskyla
#UniHelsinki @wrihelsinki.bsky.social #UniJyvaskyla
Online today! Inhibiting #cholesterol synthesis halts #rhabdomyosarcoma growth via #ERstress and cell cycle arrest
By N.Y. Gisaw, @riikka-k.bsky.social & colleagues @helsinki.fi @wrihelsinki.bsky.social
🗞️ doi.org/10.1038/s443...
By N.Y. Gisaw, @riikka-k.bsky.social & colleagues @helsinki.fi @wrihelsinki.bsky.social
🗞️ doi.org/10.1038/s443...
November 17, 2025 at 8:40 PM
Excited to share our new study showing how rhabdomyosarcoma cells respond differently to the inhibition of cholesterol synthesis compared to healthy myoblasts. Great work by a recent PhD Nebeyu Gizaw🎓
#UniHelsinki @wrihelsinki.bsky.social #UniJyvaskyla
#UniHelsinki @wrihelsinki.bsky.social #UniJyvaskyla
Our new study together with @juhahulmi.bsky.social shows that:
Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles
@wrihelsinki.bsky.social
www.biorxiv.org/content/10.1...
Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles
@wrihelsinki.bsky.social
www.biorxiv.org/content/10.1...
Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles
Skeletal muscles and blood vessels are continuously exposed to mechanical forces, particularly during exercise. We subjected human endothelial and skeletal muscle cells to cyclic mechanical stretch an...
www.biorxiv.org
October 24, 2025 at 10:40 AM
Our new study together with @juhahulmi.bsky.social shows that:
Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles
@wrihelsinki.bsky.social
www.biorxiv.org/content/10.1...
Mechanical loading induces distinct and shared responses in endothelial and muscle cells and reveals exercise-like molecular profiles
@wrihelsinki.bsky.social
www.biorxiv.org/content/10.1...
Our latest article demonstrating how human skeletal muscle use glucose for muscle growth👇
I am pleased to share our new research article (in press version) entitled Glycolytic metabolism and biomass production from glucose in human skeletal muscle growth. Link in the comments. 1/3 #myoblue #SkeletalMuscle
October 12, 2025 at 10:15 AM
Our latest article demonstrating how human skeletal muscle use glucose for muscle growth👇
Check our recent paper on the role of vasculature in skeletal muscle growth @apsphysiology.bsky.social @wrihelsinki.bsky.social
Our study led by @riikka-k.bsky.social demonstrate benefits of the combined gene delivery of Pro-MSTN and VEGF-B on muscle growth & body comp. The scRNAseq results suggest various cell types & their crosstalk in muscle growth.
tinyurl.com/4tnnrh7a
@apsphysiology.bsky.social
tinyurl.com/4tnnrh7a
@apsphysiology.bsky.social
July 8, 2025 at 5:51 AM
Check our recent paper on the role of vasculature in skeletal muscle growth @apsphysiology.bsky.social @wrihelsinki.bsky.social
www.biorxiv.org/content/10.1...
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Mechanical loading reveals cell type-specific responses and role of PHGDH in endothelial cell growth
Skeletal muscle and blood vessels are constantly subjected to mechanical forces, especially during exercise. We subjected human endothelial cells (ECs) and muscle cells (MCs) to cyclic mechanical stre...
www.biorxiv.org
July 3, 2025 at 3:44 PM
www.biorxiv.org/content/10.1...
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Reposted by Riikka Kivelä
Exciting days ahead at the Wihuri Research Institute @wrihelsinki.bsky.social as we host #WRISymposium and #EVBOSummerSchool next week in Helsinki.
Looking forward to inspiring talks and scientific exchange with the #VascularBiology community!
wri.fi/research-act...
evbo.org/index.php/ev...
Looking forward to inspiring talks and scientific exchange with the #VascularBiology community!
wri.fi/research-act...
evbo.org/index.php/ev...
Wihuri Research Institute Symposium 2025 - Wihuri Research Institute
Since 2013, the Wihuri Research Institute (WRI) has been organizing the annual WRI Symposium, providing a platform for researchers and students to share knowledge and insights in cardiovascular resear...
wri.fi
June 8, 2025 at 12:28 PM
Exciting days ahead at the Wihuri Research Institute @wrihelsinki.bsky.social as we host #WRISymposium and #EVBOSummerSchool next week in Helsinki.
Looking forward to inspiring talks and scientific exchange with the #VascularBiology community!
wri.fi/research-act...
evbo.org/index.php/ev...
Looking forward to inspiring talks and scientific exchange with the #VascularBiology community!
wri.fi/research-act...
evbo.org/index.php/ev...