Richard Goodman
@richard-goodman.bsky.social
| 📍Postdoctoral researcher at LSTM
| 🧬 Researching the evolution of antimicrobial resistance
| 🦠 Microbiology, Genomics, Bioinformatics
| 🧬 Researching the evolution of antimicrobial resistance
| 🦠 Microbiology, Genomics, Bioinformatics
I'm pleased to share our latest paper out in Communications Biology.
We used comparative genomics to determine the relatedness of E. coli and K. pneumoniae isolates from faeces and blood of the same neonates with bloodstream infections.
doi.org/10.1038/s420...
We used comparative genomics to determine the relatedness of E. coli and K. pneumoniae isolates from faeces and blood of the same neonates with bloodstream infections.
doi.org/10.1038/s420...
Comparative genomics of blood and faecal E. coli and K. pneumoniae isolates from neonates with bloodstream infections in Tanzania - Communications Biology
Genomic comparison of E. coli and K. pneumoniae isolated from faeces and blood of the same neonatal patients revealed highly related pairs, suggesting translocation between the gastrointestinal tract ...
doi.org
November 19, 2025 at 9:55 AM
I'm pleased to share our latest paper out in Communications Biology.
We used comparative genomics to determine the relatedness of E. coli and K. pneumoniae isolates from faeces and blood of the same neonates with bloodstream infections.
doi.org/10.1038/s420...
We used comparative genomics to determine the relatedness of E. coli and K. pneumoniae isolates from faeces and blood of the same neonates with bloodstream infections.
doi.org/10.1038/s420...
Reposted by Richard Goodman
Really happy to see this published, fab international collabotation and excellent analysis led by Richard Goodman
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Comparative genomics of blood and faecal E. coli and K. pneumoniae isolates from neonates with bloodstream infections in Tanzania - Communications Biology
Genomic comparison of E. coli and K. pneumoniae isolated from faeces and blood of the same neonatal patients revealed highly related pairs, suggesting translocation between the gastrointestinal tract ...
www.nature.com
November 18, 2025 at 3:02 PM
Really happy to see this published, fab international collabotation and excellent analysis led by Richard Goodman
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Pleased to share our new preprint! We used comparative genomics to determine the relatedness of E. coli and K. pneumoniae isolates from faeces and blood of the same children. We wanted to know if the bloodstream infection started in the gut; are the strains the same?
Genomic comparison of highly related pairs of E. coli and K. pneumoniae isolated from faeces and blood of the same neonatal patients hospitalized with fever in Dar es Salaam, Tanzania
Blood stream infections (BSIs) are a major cause of hospitalisation and death for children under the age of five in sub-Saharan Africa with members of the Gram-negative bacteria Enterobacterales such ...
www.biorxiv.org
April 30, 2025 at 1:44 PM
Pleased to share our new preprint! We used comparative genomics to determine the relatedness of E. coli and K. pneumoniae isolates from faeces and blood of the same children. We wanted to know if the bloodstream infection started in the gut; are the strains the same?
Reposted by Richard Goodman
Our latest preprint is out describing amr.watch - a platform for monitoring AMR trends from global genomics data: www.biorxiv.org/content/10.1... (1/6)
April 22, 2025 at 9:54 AM
Our latest preprint is out describing amr.watch - a platform for monitoring AMR trends from global genomics data: www.biorxiv.org/content/10.1... (1/6)
Reposted by Richard Goodman
Pleased to share our new preprint... We took a look into freshwater snail faecal metagenomes in four countries and found environmental #AMR reservoirs
@lstmnews.bsky.social @gcagatgcaatg.bsky.social @russstothard.bsky.social
www.biorxiv.org/content/10.1...
@lstmnews.bsky.social @gcagatgcaatg.bsky.social @russstothard.bsky.social
www.biorxiv.org/content/10.1...
Freshwater snail faecal metagenomes reveal environmental reservoirs of antimicrobial resistance genes across two continents
The transfer of antimicrobial resistance genes (ARGs) from environmental microbes to pathogens is a critical but underexplored One Health driver of antimicrobial resistance (AMR). Here, we evaluate fr...
www.biorxiv.org
February 27, 2025 at 10:33 AM
Pleased to share our new preprint... We took a look into freshwater snail faecal metagenomes in four countries and found environmental #AMR reservoirs
@lstmnews.bsky.social @gcagatgcaatg.bsky.social @russstothard.bsky.social
www.biorxiv.org/content/10.1...
@lstmnews.bsky.social @gcagatgcaatg.bsky.social @russstothard.bsky.social
www.biorxiv.org/content/10.1...
Reposted by Richard Goodman
Volume 2 of the #AMR Starter Pack is here!
go.bsky.app/EUY2FUJ
Follow these amazing people along with those in Vol. 1
go.bsky.app/KkZfvrh
And don't forget to pin the Antimicrobial Resistance feed to get all the AMR posts in one place
bsky.app/profile/did:...
go.bsky.app/EUY2FUJ
Follow these amazing people along with those in Vol. 1
go.bsky.app/KkZfvrh
And don't forget to pin the Antimicrobial Resistance feed to get all the AMR posts in one place
bsky.app/profile/did:...
December 2, 2024 at 6:52 AM
Volume 2 of the #AMR Starter Pack is here!
go.bsky.app/EUY2FUJ
Follow these amazing people along with those in Vol. 1
go.bsky.app/KkZfvrh
And don't forget to pin the Antimicrobial Resistance feed to get all the AMR posts in one place
bsky.app/profile/did:...
go.bsky.app/EUY2FUJ
Follow these amazing people along with those in Vol. 1
go.bsky.app/KkZfvrh
And don't forget to pin the Antimicrobial Resistance feed to get all the AMR posts in one place
bsky.app/profile/did:...
Reposted by Richard Goodman
New year, new assemblies!
I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes!
It's the successor to Trycycler, designed to be faster and less reliant on user intervention.
Check it out: github.com/rrwick/Autoc...
(1/5)
I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes!
It's the successor to Trycycler, designed to be faster and less reliant on user intervention.
Check it out: github.com/rrwick/Autoc...
(1/5)
Home
A tool for generating consensus long-read assemblies for bacterial genomes - rrwick/Autocycler
github.com
December 31, 2024 at 11:43 PM
New year, new assemblies!
I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes!
It's the successor to Trycycler, designed to be faster and less reliant on user intervention.
Check it out: github.com/rrwick/Autoc...
(1/5)
I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes!
It's the successor to Trycycler, designed to be faster and less reliant on user intervention.
Check it out: github.com/rrwick/Autoc...
(1/5)
Reposted by Richard Goodman
🚨 New preprint!! How can antibiotic-resistant bacteria increase in abundance in the human gut microbiome, even without antibiotics? 🧐 We show that strain-specific ecological interactions are key to understanding resistance dynamics in microbial communities. 🧵👇 1/5
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
December 11, 2024 at 12:30 PM
🚨 New preprint!! How can antibiotic-resistant bacteria increase in abundance in the human gut microbiome, even without antibiotics? 🧐 We show that strain-specific ecological interactions are key to understanding resistance dynamics in microbial communities. 🧵👇 1/5
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
As my first post on bsky post, I thought I'd share a recent paper of ours published in
@naturecomms.bsky.social
.
Here we use various techniques to determine the molecular mechanisms for an observed rise in chloramphenicol susceptibility at the same time as an increase in ESBL resistance.
@naturecomms.bsky.social
.
Here we use various techniques to determine the molecular mechanisms for an observed rise in chloramphenicol susceptibility at the same time as an increase in ESBL resistance.
Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase-producing Enterobacterales - Nature Communications
In this work, authors probe the molecular mechanism of re-emerging CHL susceptibility in Malawian Enterobacterales isolates, where they identify a stable truncation of resistance genes by insertion se...
www.nature.com
December 6, 2024 at 2:55 PM
As my first post on bsky post, I thought I'd share a recent paper of ours published in
@naturecomms.bsky.social
.
Here we use various techniques to determine the molecular mechanisms for an observed rise in chloramphenicol susceptibility at the same time as an increase in ESBL resistance.
@naturecomms.bsky.social
.
Here we use various techniques to determine the molecular mechanisms for an observed rise in chloramphenicol susceptibility at the same time as an increase in ESBL resistance.