Rose Bagot
rcbagot.bsky.social
Rose Bagot
@rcbagot.bsky.social
Neuroscientist in Montréal
Had a great time visiting USyd! Thanks for hosting me @nataliematosin.bsky.social
Wonderful visits, highlighted the need for face-to-face interactions. Cant wait for all our upcoming collabs 🙌 thanks for carving time out to come see us @drcricru.bsky.social @nikosdaskalakis.bsky.social @rcbagot.bsky.social
Grateful to host @drcricru.bsky.social, @nikosdaskalakis.bsky.social & @rcbagot.bsky.social at USYD over the last few months. Your talks highlighted the importance of our field and understanding stress in mental illness. Lots of new ideas for future collaborations. Thanks for coming!
August 20, 2025 at 8:11 PM
Reposted by Rose Bagot
Happy to announce our new paper in Nature Communications: rdcu.be/eBpGY
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep

Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social
Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus
Nature Communications - Corticotropin-releasing hormone (CRH), known for activating the HPA axis during stress, also acts centrally in the brain. Here, the authors show that CRH modulates thalamic...
rdcu.be
August 20, 2025 at 7:16 AM
Reposted by Rose Bagot
Important 'Matters Arising' from @neurome.bsky.social and Zhaoxia Yu discussing false positives due to multiple comparisons in large-scale gene expression data. I applaud Eran and others who consistently raise these issues for discussion in the community.

www.nature.com/articles/s41...
False positives in study of memory-related gene expression - Nature
Nature - False positives in study of memory-related gene expression
www.nature.com
June 5, 2025 at 12:53 PM
Sam Weiss speaking #unfiltered at the CAN-ACN EDI session. Make more jobs for Canadians! @canacn.bsky.social
May 23, 2025 at 10:57 PM
Reposted by Rose Bagot
To all those descending onto Toronto for the @canacn.bsky.social annual meeting, as program chair I hope you have an exciting meeting and enjoy our featured speakers @franklandlab.bsky.social
@yulonglilab.bsky.social @neurovoice.bsky.social @turrigiano.bsky.social and Kerry Ressler #CAN2025
May 20, 2025 at 5:39 PM
Reposted by Rose Bagot
#resilience2025 fantastic speaker line-up: Andrew Holmes, Moh Milad, Dominique de Quervain @dequervain.bsky.social, Birgit Kleim, Rose Bagot @rcbagot.bsky.social, Floris Klumpers, Patricia Molina @pmolinamolina.bsky.social, Marianne Müller, Penny Lewis, Niels Niethard @nniethard.bsky.social, ...
Symposium 2025 | LIR Mainz - Leibniz-Institut für Resilienzforschung
lir-mainz.de
May 14, 2025 at 8:06 AM
Reposted by Rose Bagot
Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation.

rdcu.be/el18q

A short thread follows for those interested.

1/n
Systems consolidation reorganizes hippocampal engram circuitry
Nature - A study shows that loss of memory precision associated with systems consolidation can be explained by neurogenesis-dependent reorganization of engram circuitry within the hippocampus over...
rdcu.be
May 14, 2025 at 4:32 PM
Reposted by Rose Bagot
If you are in Toronto on Tuesday next week, please consider coming to see a FREE public lecture on memory, delivered by the amazing @sjo09.bsky.social and @barense.bsky.social . Tix at this link can-acn.org/meeting-2025... Please repost and hope to see you there!
CAN 2025 Public Lectures: Neuroscience of memory and tools for making our memories stronger – Canadian Association for Neuroscience
can-acn.org
May 14, 2025 at 7:15 PM
Reposted by Rose Bagot
Really excited to share this new preprint led by senior PhD student Liz Herrera Portillo who is co-supervised by
@rcbagot.bsky.social
!!

We use longitudinal MRI to show that mice exposed stress undergo sex-specific neuroanatomical reorganization.

www.biorxiv.org/content/10.1...
Whole brain dimensional approach identifies shared and sex-specific networks of stress susceptibility in male and female mice.
Background: Stress is a significant risk factor for depression and anxiety, two highly comorbid disorders with sex differences in symptom presentation and prevalence. The Chronic Variable Stress (CVS)...
www.biorxiv.org
May 12, 2025 at 3:27 PM
Looking forward to exploring exciting new directions together!
Excited to share that I’ll be starting as a postdoc in @rcbagot.bsky.social’s lab at @mcgilluniversity.bsky.social, studying the neural mechanisms of psychedelics ✨🐁🌀 Grateful for this new adventure into the unknown.
April 18, 2025 at 1:04 AM
Reposted by Rose Bagot
Our latest work led by @claraliao.bsky.social is a collaboration with the other Kwan lab @kwanlab.bsky.social

We used single-nucleus RNA sequencing to measure transcriptional responses in the mouse medial frontal cortex following a single dose of psilocybin. 🍄 🧠 🧬

www.biorxiv.org/content/10.1...
January 6, 2025 at 12:49 PM
New lab preprint ! There is a lot of excitement about the therapeutic potential of psilocybin but what is the mechanism? A beautiful body of work from @alexkwan.bsky.social shows that PFC plasticity is important. But how does this unfold and in which cell types?

www.biorxiv.org/content/10.1...
January 9, 2025 at 1:42 AM