Ratnasekhar CH
ratnasekharlab.bsky.social
Ratnasekhar CH
@ratnasekharlab.bsky.social
Metabolomics Scientist & Assistant Professor. Previous postdoc fellow at University of Cambridge and Queen's University Belfast.

https://www.ratnasekhar-metabolomics-lab.com/
Reposted by Ratnasekhar CH
#Throwback 🧪

COMMENT | ‪ Subcellular quantitative imaging of metabolites at the organelle level

@siuzdak.bsky.social‬
Subcellular quantitative imaging of metabolites at the organelle level - Nature Metabolism
Subcellular quantitative analysis has been a long-standing goal of mass spectrometry imaging, but was originally thought to be unattainable. However, recent advances have made organelle-level absolute quantification through mass spectrometry imaging a reality, thanks to the development of nano secondary ion mass spectrometry.
bit.ly
July 19, 2025 at 3:02 PM
Reposted by Ratnasekhar CH
75% of acute lymphoblastic leukemia (ALL) cases are in kids under 6.

1960s: ALL survival was 10%.

Today: Survival is over 90%.

That’s because of chemotherapy.
Not supplements, “detoxes,” juice, or wellness bullshit.

Chemotherapy saves lives.
Misinformation kills.

Read more in Immunologic ⬇️
Cancer misinformation kills. Chemotherapy saves lives.
Rejecting evidence-based treatment in favor of false hope and wellness industry lies is deadly.
news.immunologic.org
April 30, 2025 at 7:09 PM
Reposted by Ratnasekhar CH
Relationship between exhaled volatile organic compounds and lung function change in idiopathic pulmonary fibrosis #Thorax #MassSpec thorax.bmj.com/content/earl...
Relationship between exhaled volatile organic compounds and lung function change in idiopathic pulmonary fibrosis
Volatile organic compounds (VOCs) in exhaled breath have shown promise as biomarkers in idiopathic pulmonary fibrosis (IPF). We analysed breath from 57 people with IPF using thermal desorption–gas chr...
thorax.bmj.com
May 1, 2025 at 7:50 AM
Insightful lecture by Dr. ‪Natalie Homer (University of Edinburgh) on LC-MS/MS-based profiling of steroidal hormones at the International Conference on Metabolomics & Lipidomics at IIT Bombay. #Metabolomics #Lipidomics #LCMSMS
March 2, 2025 at 12:44 PM
Honoured to deliver talk at the International Conference on Metabolomics & Lipidomics at IIT Bombay. An excellent event bringing together renowned speakers from across the globe, showcasing diversity in metabolomics and lipidomics research. #Metabolomics #Lipidomics
March 2, 2025 at 12:29 PM
"Had a fantastic time at the Metabolomics & Lipidomics symposium organized at DBT-RGCB, Thiruvananthapuram! A great gathering of researchers, insightful discussions, and an opportunity to present our work. Thanks to Prof. Jaleel for hosting this wonderful event! #Metabolomics #Lipidomics"
February 24, 2025 at 1:54 PM
Reposted by Ratnasekhar CH
Great to see paper from Alva Casey out today in Nature Metabolism - from her PhD.
Well done Alva!

doi.org/10.1038/s422...
Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation - Nature Metabolism
Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.
doi.org
February 19, 2025 at 12:06 PM
I am delighted to deliver an invited talk at the International Conference on Metabolomics and Lipidomics (metabolomics.global), taking place from February 25–26, 2025, at IIT Bombay. This conference offers a fantastic platform for faculty, technocrats, students. #metabolomics
February 18, 2025 at 4:11 PM