Noelle Held
@proteocean.bsky.social
proteomics, cellular decision-making, and biogeochemical cycles. assistant professor of marine & environmental biology @ USC. Also a yoga teacher. Your best is enough.
Reposted by Noelle Held
🌊Curious how multi-nutrient scarcity impacts marine microbes🦠? Excited to announce our #OSM26 session, Glasgow Feb 22-27! Join us in bridging cell biology, modelling & oceanography! tinyurl.com/zzt5s9su @exetermarine.bsky.social @thembauk.bsky.social @proteocean.bsky.social @cmarkmoore.bsky.social
Nutrient Co-limitation of Marine Microbes: Exploring Cellular to Ecosystem-Level Effects
Nutrient availability limits microbial growth in marine ecosystems globally. Accumulating evidence has highlighted the prevalence of nutrient co-limitation, whereby two or more nutrients restrict mari...
tinyurl.com
July 31, 2025 at 8:34 AM
🌊Curious how multi-nutrient scarcity impacts marine microbes🦠? Excited to announce our #OSM26 session, Glasgow Feb 22-27! Join us in bridging cell biology, modelling & oceanography! tinyurl.com/zzt5s9su @exetermarine.bsky.social @thembauk.bsky.social @proteocean.bsky.social @cmarkmoore.bsky.social
I am hiring a research/technical specialist/manager to help us make the most out of new LC-MS instrumentation at USC! Please share the word and write me for more details. usc.wd5.myworkdayjobs.com/en-US/Extern...
Assistant Director of the Center for Proteomics Discovery (Research Program Administrator)
The USC Dana and David Dornsife College of Letters, Arts and Sciences is seeking a Research Program Administrator (non-Clinical) and Assistant Director of the USC Center for Proteomics Discovery. This...
usc.wd5.myworkdayjobs.com
June 5, 2025 at 4:43 PM
I am hiring a research/technical specialist/manager to help us make the most out of new LC-MS instrumentation at USC! Please share the word and write me for more details. usc.wd5.myworkdayjobs.com/en-US/Extern...
Super glad to share two new papers about how nutrient gradients impact alkaline phosphatase in the ocean. This was "that project" which followed from PhD to Postdoc to Assist. Prof, motivated by awesome collaborators! egusphere.copernicus.org/preprints/20... egusphere.copernicus.org/preprints/20...
Part 1: Zonal gradients in phosphorus and nitrogen acquisition and stress revealed by metaproteomes of Prochlorococcus and Synechococcus
Abstract. Ocean warming alongside changes to the natural and anthropogenic supply of key nutrient resources such as nitrogen, phosphorus and trace metals is predicted to alter the magnitude and stoich...
egusphere.copernicus.org
March 4, 2025 at 9:57 PM
Super glad to share two new papers about how nutrient gradients impact alkaline phosphatase in the ocean. This was "that project" which followed from PhD to Postdoc to Assist. Prof, motivated by awesome collaborators! egusphere.copernicus.org/preprints/20... egusphere.copernicus.org/preprints/20...
🔥Thanks, Don Beyer and staff!
The Trump Administration's list of censored scientific terms that get NSF grant proposals flagged contains "women” and “female”, but no mention of “men” or “male.” There is “black” and “indigenous” on this list, but no “white.” The only identity not censored is mine.
youtu.be/dHXbpj1Z3UU
youtu.be/dHXbpj1Z3UU
Don Beyer Speaks About Trump's NSF Censorship on the House Floor
YouTube video by Congressman Don Beyer
youtu.be
February 7, 2025 at 9:13 PM
🔥Thanks, Don Beyer and staff!
Reposted by Noelle Held
🚨 The Trump administration is attempting to seize power beyond what the Constitution allows—giving Elon Musk, an unelected billionaire, unchecked influence.
As a federal scientist, expert, or civil servant, you have rights. Don’t let them bully you.
These resources can help: act.ucsusa.org/4hqSJoz
As a federal scientist, expert, or civil servant, you have rights. Don’t let them bully you.
These resources can help: act.ucsusa.org/4hqSJoz
February 6, 2025 at 4:11 PM
🚨 The Trump administration is attempting to seize power beyond what the Constitution allows—giving Elon Musk, an unelected billionaire, unchecked influence.
As a federal scientist, expert, or civil servant, you have rights. Don’t let them bully you.
These resources can help: act.ucsusa.org/4hqSJoz
As a federal scientist, expert, or civil servant, you have rights. Don’t let them bully you.
These resources can help: act.ucsusa.org/4hqSJoz
We’ve been sampling the Santa Monica bay since Jan for changes in the marine microbiome due to runoff of debris from the fires. Today I brought a sampling buddy along. We should teach him to pull the cart.
February 6, 2025 at 3:23 PM
We’ve been sampling the Santa Monica bay since Jan for changes in the marine microbiome due to runoff of debris from the fires. Today I brought a sampling buddy along. We should teach him to pull the cart.
Reposted by Noelle Held
Reiterating my call to fellow federally-funded scientists: Call your reps, tell them how this hurts science and everything good that comes from science
(Also non-scientists, and scientists without federal funding! But the more of us who can directly speak to the impacts of these freezes the better)
(Also non-scientists, and scientists without federal funding! But the more of us who can directly speak to the impacts of these freezes the better)
The National Science Foundation cancelled over 60 grant review panels today, effectively grinding funding of new projects to a halt.
The so-far indefinite pause comes as NSF grapples with the impact Trump's executive orders will have on their grantmaking process.
www.npr.org/sections/sho...
The so-far indefinite pause comes as NSF grapples with the impact Trump's executive orders will have on their grantmaking process.
www.npr.org/sections/sho...
National Science Foundation freezes grant review in response to Trump executive orders
The National Science Foundation has cancelled all grant review panels this week. It's unclear how long the pause could last.
www.npr.org
January 28, 2025 at 12:26 AM
Reiterating my call to fellow federally-funded scientists: Call your reps, tell them how this hurts science and everything good that comes from science
(Also non-scientists, and scientists without federal funding! But the more of us who can directly speak to the impacts of these freezes the better)
(Also non-scientists, and scientists without federal funding! But the more of us who can directly speak to the impacts of these freezes the better)
Reposted by Noelle Held
MICO/Brisbin lab is hosting Making Waves REUs this summer! Please share with your favorite undergrads! Are you an undergrad excited about oceanography? Apply or reach out with questions! #reu #microbialsky
January 16, 2025 at 5:19 PM
MICO/Brisbin lab is hosting Making Waves REUs this summer! Please share with your favorite undergrads! Are you an undergrad excited about oceanography? Apply or reach out with questions! #reu #microbialsky
I really wanted a long distance penpal as a kid - so a fun upside of the transientness of early career academia is that I am now sending new years cards to friends all over the world - just posted to Germany, Australia, Switzerland, the UK, Italy, Russia, France, Canada, and Chile!
January 1, 2025 at 9:36 PM
I really wanted a long distance penpal as a kid - so a fun upside of the transientness of early career academia is that I am now sending new years cards to friends all over the world - just posted to Germany, Australia, Switzerland, the UK, Italy, Russia, France, Canada, and Chile!
Reposted by Noelle Held
We showed that #metaproteomics based "Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo"
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo
Diet has strong impacts on the composition and function of the gut microbiota with implications for host health. Therefore, it is critical to identify the dietary components that support growth of spe...
www.biorxiv.org
December 27, 2024 at 5:18 PM
We showed that #metaproteomics based "Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo"
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
More good news to round out the year, Proteocean Lab PhD student Mia Franks is a Wrigley Institute Graduate Fellow! She joins a very cool, very diverse group of student researchers and will quantify nutrient colimitation in the San Pedro Channel. Yay Mia! dornsife.usc.edu/wrigley/2024...
Meet the 2025 Wrigley Institute Graduate Fellows - Wrigley Institute for Environment and Sustainability
Creating a more sustainable and environmentally just future for our planet and all who live on it
dornsife.usc.edu
December 20, 2024 at 8:41 PM
More good news to round out the year, Proteocean Lab PhD student Mia Franks is a Wrigley Institute Graduate Fellow! She joins a very cool, very diverse group of student researchers and will quantify nutrient colimitation in the San Pedro Channel. Yay Mia! dornsife.usc.edu/wrigley/2024...
What does it really mean to be in nutrient colimitation? We demonstrate a distinct growth phenotype and that (co)limitation can (and should!) be quantified. The result of many late afternoon chats with @michaelmanhart.bsky.social. Let us know what you think! www.pnas.org/doi/10.1073/pnas.2400304121
www.pnas.org
December 18, 2024 at 7:27 PM
What does it really mean to be in nutrient colimitation? We demonstrate a distinct growth phenotype and that (co)limitation can (and should!) be quantified. The result of many late afternoon chats with @michaelmanhart.bsky.social. Let us know what you think! www.pnas.org/doi/10.1073/pnas.2400304121
5 years ago toda I defended my thesis (thanks for the reminder @maksaito.bsky.social!) 1 year ago today was my first day in LA. Time flies! The dog is not impressed.
December 6, 2024 at 8:39 PM
5 years ago toda I defended my thesis (thanks for the reminder @maksaito.bsky.social!) 1 year ago today was my first day in LA. Time flies! The dog is not impressed.
Reposted by Noelle Held
We're still looking for a postdoc in metabolic modeling and culture-based validation. If it sounds like you, reach out to discuss! www.isme-microbes.org/jobs/postdoc...
April 30, 2024 at 6:29 PM
We're still looking for a postdoc in metabolic modeling and culture-based validation. If it sounds like you, reach out to discuss! www.isme-microbes.org/jobs/postdoc...
And it takes me two weeks to install a python library.
Just incredible news on reviving Voyager I.
Think of it: a computer chip 15 billion(!) miles away is broken. The solution is to repackage & move key software, w/ code sent via radio signal that takes 22+ hrs to reach that little 46yr old machine.
AND IT IS WORKING.
blogs.nasa.gov/voyager/2024...
Think of it: a computer chip 15 billion(!) miles away is broken. The solution is to repackage & move key software, w/ code sent via radio signal that takes 22+ hrs to reach that little 46yr old machine.
AND IT IS WORKING.
blogs.nasa.gov/voyager/2024...
NASA’s Voyager 1 Resumes Sending Engineering Updates to Earth – Voyager
blogs.nasa.gov
April 23, 2024 at 3:20 AM
And it takes me two weeks to install a python library.
Starting my rejections garden. Adding a plant for every no. Going strong at 4 months in - I’ll have an epic office garden in no time. Anyway, even though it feels crummy, there can be growth. 🌿
April 17, 2024 at 11:58 PM
Starting my rejections garden. Adding a plant for every no. Going strong at 4 months in - I’ll have an epic office garden in no time. Anyway, even though it feels crummy, there can be growth. 🌿
Has anyone had experience with a preprint being published, along with a bunch of AI text and a fake image, on one of those NFT sites? It grosses me out, not sure of legality??
April 9, 2024 at 3:44 PM
Has anyone had experience with a preprint being published, along with a bunch of AI text and a fake image, on one of those NFT sites? It grosses me out, not sure of legality??
Reposted by Noelle Held
Microbes need many different resources, but do some of these resources simultaneously COLIMIT growth? @proteocean.bsky.social and I provide a new review of this concept, a summary of evidence that colimitation occurs in natural environments, and its causes/consequences. doi.org/10.32942/X2S... 1/6
Are microbes colimited by multiple resources?
doi.org
March 5, 2024 at 4:52 AM
Microbes need many different resources, but do some of these resources simultaneously COLIMIT growth? @proteocean.bsky.social and I provide a new review of this concept, a summary of evidence that colimitation occurs in natural environments, and its causes/consequences. doi.org/10.32942/X2S... 1/6
Time for another new lab poll - What ultra pure water system does your lab have and do you like it?
March 1, 2024 at 2:46 AM
Time for another new lab poll - What ultra pure water system does your lab have and do you like it?
Second growth on HEPES and basically all buffers.
Whenever we do nutrient limitation experiments (usually N and P, less often S) we *always* test if the organism can extract nutrients from the buffer. Pretty sure HEPES can be broken down too.
February 9, 2024 at 2:10 AM
Second growth on HEPES and basically all buffers.
Cool opportunity if you’d like to postdoc at USC and work across departments in sustainability! Awesomely, the fellowship includes targeted career development! We’re ramping up relevant themes in the proteocean lab, contact me! www.ssf.usc.edu
January 9, 2024 at 7:58 PM
Cool opportunity if you’d like to postdoc at USC and work across departments in sustainability! Awesomely, the fellowship includes targeted career development! We’re ramping up relevant themes in the proteocean lab, contact me! www.ssf.usc.edu
In times like these the Oceanography training really pays off - I basically got a PhD in shipping weird stuff halfway across the world.
November 25, 2023 at 1:17 PM
In times like these the Oceanography training really pays off - I basically got a PhD in shipping weird stuff halfway across the world.
First instance of helpless panic waiting for a grant to route through approvals, minutes before agency deadline: ✅ Also, first instance of grant manager angel saving the day: ✅ What right of passage is next?
November 16, 2023 at 9:04 AM
First instance of helpless panic waiting for a grant to route through approvals, minutes before agency deadline: ✅ Also, first instance of grant manager angel saving the day: ✅ What right of passage is next?
Reposted by Noelle Held
Our lab is recruiting a Ph.D. student for fall 2024! If you are interested in the ecology, evolution, and systems biology of microbial communities (especially using theory and modeling), please apply by November 1 according to the attached ad and link
qevomicrolab.org/wp-content/u...
qevomicrolab.org/wp-content/u...
October 3, 2023 at 11:57 PM
Our lab is recruiting a Ph.D. student for fall 2024! If you are interested in the ecology, evolution, and systems biology of microbial communities (especially using theory and modeling), please apply by November 1 according to the attached ad and link
qevomicrolab.org/wp-content/u...
qevomicrolab.org/wp-content/u...
Let’s talk about nutrient (co)limitation as a quantitative property of microbial populations and communities! Plus, we show that colimitation for two essential nutrients is accessible in laboratory conditions. Preprint here: www.biorxiv.org/content/10.1...
September 28, 2023 at 7:06 AM
Let’s talk about nutrient (co)limitation as a quantitative property of microbial populations and communities! Plus, we show that colimitation for two essential nutrients is accessible in laboratory conditions. Preprint here: www.biorxiv.org/content/10.1...