Pilhofer Lab 🦠❄️🔬
banner
pilhoferlab.bsky.social
Pilhofer Lab 🦠❄️🔬
@pilhoferlab.bsky.social
Microbial cell-cell interactions | contractile injection systems | cytoskeleton | evolution | multiscale imaging | ETH Zürich
- run by lab members -
Reposted by Pilhofer Lab 🦠❄️🔬
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
November 7, 2025 at 11:02 AM
Florian also adapted expansion microscopy to archaeal cells, which will most certainly leverage future exciting insights into Asgards. Florian - we're looking forward to reading🤓 your future papers 📜
Soo glad that we all could be a part of your journey 🙏
-Martin
November 1, 2025 at 12:41 PM
Florian found that their peculiar cellular architecture🦠 was scaffolded by an actin cytoskeleton🦴. In a follow-up, Florian et al. also discovered microtubules comprising eukaryote-like tubulins, which brought this line of research back to my own roots!-- microtubules in bacteria
November 1, 2025 at 12:41 PM
Here is one of the first images Florian recorded in 2021 after many hours of hunting Asgards in the microscope. My advice at the time: "Keep going- just don't tell your structural biology colleagues that you're burning days of Krios time in pursuit of weird cells in a poorly characterized sample ;)"
November 1, 2025 at 12:41 PM