Kate McCluskey
@pieceofkate.bsky.social
she/her | UCSF Neuroscience PhD in Helen Willsey's Lab 🐸
Pinned
Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility - Nature Communications
Gastrointestinal distress is common among individuals with autism. Here, authors show that autism gene variants disrupt enteric neuron migration and cause gut dysmotility. They identify a common SSRI ...
www.nature.com
Excited to share my paper now published at @naturecomms.bsky.social ! We provide evidence that autism gene variants affect enteric neuron migration and cause gastrointestinal dysmotilty. Check it out ! www.nature.com/articles/s41...
Reposted by Kate McCluskey
McCluskey et al. publish in Nature Communications how expression of autism genes is enriched in migratory embryonic gut progenitors causing GI dismotility. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
April 22, 2025 at 9:56 PM
McCluskey et al. publish in Nature Communications how expression of autism genes is enriched in migratory embryonic gut progenitors causing GI dismotility. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
Excited to share my paper now published at @naturecomms.bsky.social ! We provide evidence that autism gene variants affect enteric neuron migration and cause gastrointestinal dysmotilty. Check it out ! www.nature.com/articles/s41...
Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility - Nature Communications
Gastrointestinal distress is common among individuals with autism. Here, authors show that autism gene variants disrupt enteric neuron migration and cause gut dysmotility. They identify a common SSRI ...
www.nature.com
March 7, 2025 at 4:15 AM
Excited to share my paper now published at @naturecomms.bsky.social ! We provide evidence that autism gene variants affect enteric neuron migration and cause gastrointestinal dysmotilty. Check it out ! www.nature.com/articles/s41...
Reposted by Kate McCluskey
Join us for the fantastic annual @cshlnews.bsky.social #Xenopus cell & developmental Biology course.
Deadline for application is Jan 31st.
meetings.cshl.edu/courses.aspx...
Deadline for application is Jan 31st.
meetings.cshl.edu/courses.aspx...
January 22, 2025 at 11:22 AM
Join us for the fantastic annual @cshlnews.bsky.social #Xenopus cell & developmental Biology course.
Deadline for application is Jan 31st.
meetings.cshl.edu/courses.aspx...
Deadline for application is Jan 31st.
meetings.cshl.edu/courses.aspx...
Reposted by Kate McCluskey
Congratulations to newly PhD'ed
@pieceofkate.bsky.social Dr. McCluskey!! She gave a fantastic thesis seminar to cap it off 👏🎓🐸✨
@pieceofkate.bsky.social Dr. McCluskey!! She gave a fantastic thesis seminar to cap it off 👏🎓🐸✨
January 21, 2025 at 6:49 PM
Congratulations to newly PhD'ed
@pieceofkate.bsky.social Dr. McCluskey!! She gave a fantastic thesis seminar to cap it off 👏🎓🐸✨
@pieceofkate.bsky.social Dr. McCluskey!! She gave a fantastic thesis seminar to cap it off 👏🎓🐸✨
Reposted by Kate McCluskey
🎉 Congrats to the wonderful and talented @elinakosty.bsky.social !! Check out her exciting new preprint where she shows that autism proteins (chromatin regulators and synaptic proteins ! ) converge to localize on cilia
Plus she'll be at ASCB @ascbiology.bsky.social to talk more about it!
Plus she'll be at ASCB @ascbiology.bsky.social to talk more about it!
Check out our new ✨preprint ✨📝 describing extraordinary convergence of autism proteins at the cilium, a 🧵
www.biorxiv.org/content/10.1... (1/ )
www.biorxiv.org/content/10.1... (1/ )
Convergence of autism proteins at the cilium
Hundreds of high confidence autism genes have been identified, yet the relevant etiological mechanisms remain unclear. Gene ontology analyses have repeatedly identified enrichment of proteins with ann...
www.biorxiv.org
December 10, 2024 at 2:54 AM
🎉 Congrats to the wonderful and talented @elinakosty.bsky.social !! Check out her exciting new preprint where she shows that autism proteins (chromatin regulators and synaptic proteins ! ) converge to localize on cilia
Plus she'll be at ASCB @ascbiology.bsky.social to talk more about it!
Plus she'll be at ASCB @ascbiology.bsky.social to talk more about it!
Xenopus is an awesome model for ENS development !
Happy #FluorescenceFriday from this #Xenopus tadpole gut stained for acetylated tubulin (magenta) and calretinin (green). By @pieceofkate.bsky.social who has been studying the development of enteric neurons in frog! (Zeiss Zoom widefield scope with apotome)
November 22, 2024 at 5:56 PM
Xenopus is an awesome model for ENS development !
Check out James’ cool new paper! Using cilia in frogs 🐸 to study KANSL1 and translating those findings to humans !
Check out our new ✨preprint✨ led by James Schmidt! Here we identified a new role for the gene KANSL1 in ciliary biology using Xenopus, with validations in patients with associated Koolen-de Vries Syndrome, which is characterized by hypersociability. www.biorxiv.org/content/10.1...
November 15, 2024 at 3:56 PM
Check out James’ cool new paper! Using cilia in frogs 🐸 to study KANSL1 and translating those findings to humans !