Frog Wranglers
@frogwranglers.bsky.social
Giving you your moment of Xen(opus). Currently managed by Helen Willsey #xenopus #devbio #cellbio
Reposted by Frog Wranglers
This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...
July 8, 2025 at 12:41 AM
This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...
Reposted by Frog Wranglers
What Carole said -
This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...
July 8, 2025 at 1:13 AM
What Carole said -
Reposted by Frog Wranglers
Reposted by Frog Wranglers
It is absolutely crazy to think we no longer need model organism research. www.sciencedirect.com/science/arti...
There is no replacement for animal models in medical research
www.sciencedirect.com
July 9, 2025 at 9:02 PM
It is absolutely crazy to think we no longer need model organism research. www.sciencedirect.com/science/arti...
Reposted by Frog Wranglers
It is absolutely crazy to think we no longer need model organism research. - Carole Labonne www.sciencedirect.com/science/arti... #science #devbio #xenopus #frogs
July 10, 2025 at 2:43 PM
It is absolutely crazy to think we no longer need model organism research. - Carole Labonne www.sciencedirect.com/science/arti... #science #devbio #xenopus #frogs
Reposted by Frog Wranglers
here is the link: www.fda.gov/news-events/...
FDA-NIH Workshop: Reducing Animal Testing
The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.
www.fda.gov
July 11, 2025 at 4:34 PM
here is the link: www.fda.gov/news-events/...
This is mission CRITICAL. Please comment.
Dear all, PLEASE add comments on the importance of model organism research at this link:
July 11, 2025 at 4:40 PM
This is mission CRITICAL. Please comment.
Legend!
Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs
May 22, 2025 at 4:54 PM
Legend!
Reposted by Frog Wranglers
Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs
May 14, 2025 at 2:49 PM
Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs
Reposted by Frog Wranglers
Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
May 14, 2025 at 3:34 PM
Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
Reposted by Frog Wranglers
The International Xenopus Board (IXB) Young Investigator Award recognizes an outstanding junior faculty member from any country making significant scientific achievements using Xenopus. Nominations due June 20, 2025. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
May 14, 2025 at 6:14 PM
The International Xenopus Board (IXB) Young Investigator Award recognizes an outstanding junior faculty member from any country making significant scientific achievements using Xenopus. Nominations due June 20, 2025. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
Reposted by Frog Wranglers
Thank you for the opportunity to speak about our work amongst so many cool talks! 🐸✨
Our last short talk of the day was Sarah Bowden @sarahbowden.bsky.social from @uni-freiburg.de on the role of Foxi1 for mucociliary progenitor and ectodermal specification in Xenopus
May 20, 2025 at 6:29 AM
Thank you for the opportunity to speak about our work amongst so many cool talks! 🐸✨
Reposted by Frog Wranglers
Excited for day one of the first @ epilepsyinst.bsky.social conference! If you ever wanted to know how tadpoles can help us understand DEE please come and chat at poster 2
Epilepsy Research Institute (@epilepsyinst.bsky.social)
Radically advancing epilepsy research.
epilepsyinst.bsky.social
May 22, 2025 at 8:41 AM
Excited for day one of the first @ epilepsyinst.bsky.social conference! If you ever wanted to know how tadpoles can help us understand DEE please come and chat at poster 2
Froggers post up!
Hello fellow froggers! Just over a week until the deadline for the Nikon Small World microscopy competition. Submit your images and show off the power of Xenopus! enter.nikonsmallworld.com #science #devbio #nikon #microscopy #xenopus #frogs
April 24, 2025 at 10:33 PM
Froggers post up!
Reposted by Frog Wranglers
So incredibly happy that Ray Keller was elected to the AAAS! He's a pioneer of the cell biology of morphogenesis and of embryo mechanics, and a hero of mine. So grateful for his outstanding work. Even more grateful that he always took me seriously congrats Ray!!!
www.amacad.org/new-members-...
www.amacad.org/new-members-...
New Academy Members
Elected in 2025
www.amacad.org
April 23, 2025 at 7:43 PM
So incredibly happy that Ray Keller was elected to the AAAS! He's a pioneer of the cell biology of morphogenesis and of embryo mechanics, and a hero of mine. So grateful for his outstanding work. Even more grateful that he always took me seriously congrats Ray!!!
www.amacad.org/new-members-...
www.amacad.org/new-members-...
CRISPRi in frogs! cellandbioscience.biomedcentral.com/articles/10....
CRISPR/Cas-mediated mRNA knockdown in the embryos of Xenopus tropicalis - Cell & Bioscience
The Xenopus tropicalis (Western clawed frog) is an important amphibian model for genetics, developmental and regenerative biology, due to its diploid genetic background and short generation time. CRIS...
cellandbioscience.biomedcentral.com
April 24, 2025 at 10:30 PM
CRISPRi in frogs! cellandbioscience.biomedcentral.com/articles/10....
Cool new work on metabolic activity in embryonic cell migration using #xenopus! journals.biologists.com/jcs/article/...
April 14, 2025 at 5:14 PM
Cool new work on metabolic activity in embryonic cell migration using #xenopus! journals.biologists.com/jcs/article/...
#xenopus and chickens coming together to parse Six1 targets and deafness risk genes! journals.biologists.com/dev/article/...
April 14, 2025 at 5:12 PM
#xenopus and chickens coming together to parse Six1 targets and deafness risk genes! journals.biologists.com/dev/article/...
Check it out! #xenopus 🐸
REPOSTING this here just to officially leave "the other place"
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Stretch-induced endogenous electric fields drive directed collective cell migration in vivo - Nature Materials
Electric fields guide collective cell migration in developing embryos of Xenopus laevis via a voltage-sensitive phosphatase.
nature.com
April 8, 2025 at 2:11 AM
Check it out! #xenopus 🐸
Reposted by Frog Wranglers
“We want to do something more interactive,” my graduate cell biology students said. “Like what?” I replied.
April 7, 2025 at 4:11 PM
“We want to do something more interactive,” my graduate cell biology students said. “Like what?” I replied.
Cool new #xenopus paper on the contribution of sperm epigenetic marks on development! www.nature.com/articles/s41...
April 8, 2025 at 2:08 AM
Cool new #xenopus paper on the contribution of sperm epigenetic marks on development! www.nature.com/articles/s41...
Reposted by Frog Wranglers
Does anyone know why Ensembl no longer have genome sequence of Xenopus laevis anymore??? Or am I missing something? Has this always been the case? @ensembl.bsky.social
March 31, 2025 at 2:50 PM
Does anyone know why Ensembl no longer have genome sequence of Xenopus laevis anymore??? Or am I missing something? Has this always been the case? @ensembl.bsky.social
Check it out! #xenopus to the rescue for functional genetics! 🧬 🐸
So stoked to have a small part in this awesome paper @nature.com on human spina bifida with Jiny Ha, Sangwoo Kim, Joe Gleeson and others. Chanjae Lee did ALL the heavy lifting for the in vivo validations in my lab. this great work was ONLY possible thanks to the NIH!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The contribution of de novo coding mutations to meningomyelocele - Nature
Exome sequencing of 851 trios from more than 2,500 individuals finds 187 genes with de novo mutations that contribute to meningomyelocele (spina bifida) and highlights critical pathways required for n...
www.nature.com
April 2, 2025 at 2:16 PM
Check it out! #xenopus to the rescue for functional genetics! 🧬 🐸
Check it out! 🤩🐸✨
Do you work with reprogrammed cells? Then look at our new paper!
We asked: How well do reprogrammed cells differentiate into complete&functional tissues?
We found that
- some cell types form perfectly but others fail
- reducing levels of one specific TF of the previous lineage can fix problems⬇️
We asked: How well do reprogrammed cells differentiate into complete&functional tissues?
We found that
- some cell types form perfectly but others fail
- reducing levels of one specific TF of the previous lineage can fix problems⬇️
Differentiation success of reprogrammed cells is heterogeneous in vivo and modulated by somatic cell identity memory
This study investigates how reprogramming success in vivo varies across cell types,
revealing that gene expression of the previous somatic cell identity hinders proper
differentiation. By following si...
www.cell.com
March 15, 2025 at 12:51 AM
Check it out! 🤩🐸✨
Think you’re stressed? Check out this new work on inducing tissue strain coupled to live imaging 🐸✨ pubmed.ncbi.nlm.nih.gov/40059484/
March 11, 2025 at 1:39 PM
Think you’re stressed? Check out this new work on inducing tissue strain coupled to live imaging 🐸✨ pubmed.ncbi.nlm.nih.gov/40059484/